design and synthesis of gd3 based mri contrast agents

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Lothar Helm The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging Lothar Helm The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging
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Lothar Helm The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging


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17023.2 руб.

Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement. This completely revised and extended second edition: Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations. Is written for all of those involved in the development and application of contrast agents in MRI. Presented in colour, it provides readers with true representation and easy interpretation of the images. A word from the Authors: Twelve years after the first edition published, we are convinced that the chemistry of MRI agents has a bright future. By assembling all important information on the design principles and functioning of magnetic resonance imaging probes, this book intends to be a useful tool for both experts and newcomers in the field. We hope that it helps inspire further work in order to create more efficient and specific imaging probes that will allow materializing the dream of seeing even deeper and better inside the living organisms. Reviews of the First Edition: «…attempts, for the first time, to review the whole spectrum of involved chemical disciplines in this technique…»—Journal of the American Chemical Society «…well balanced in its scope and attention to detail…a valuable addition to the library of MR scientists…»—NMR in Biomedicine

Rosaleen Anderson Antibacterial Agents. Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications Rosaleen Anderson Antibacterial Agents. Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications
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Rosaleen Anderson Antibacterial Agents. Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications


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13648.01 руб.

Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA – quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes – sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis – aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis – β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.

Tim Storr Ligand Design in Medicinal Inorganic Chemistry Tim Storr Ligand Design in Medicinal Inorganic Chemistry
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Tim Storr Ligand Design in Medicinal Inorganic Chemistry


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14623.43 руб.

Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.

Jonathan McConnell Index of Medical Imaging Jonathan McConnell Index of Medical Imaging
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Jonathan McConnell Index of Medical Imaging


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3966.7 руб.

The ‘Index of Medical Imaging' is the must-have companion for diagnostic radiography students and newly qualified imaging practitioners, designed to allow easy access to descriptions and discussions of many aspects of medical imaging such as radiographic projections, positioning, procedures and clinical examinations. The Index consists of multiple lists, tables and discussions linked to (amongst others) radiography, CT, MRI and components such as radiological contrast agents, responses to contrast reactions, MRI safety. There is a glossary of terms and definitions plus a list of abbreviations that may be encountered within radiology. Tables are given that suggest the order and type of examination that should be performed as defined by the UK Royal College of Radiologists. FEATURES • Supports clinical decision-making • Glossary of key terms and abbreviations • Unique format that consists of multiple lists, tables and discussions

Xing Wei Boolean Circuit Rewiring. Bridging Logical and Physical Designs Xing Wei Boolean Circuit Rewiring. Bridging Logical and Physical Designs
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Xing Wei Boolean Circuit Rewiring. Bridging Logical and Physical Designs


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10498.36 руб.

Demonstrates techniques which will allow rewiring rates of over 95%, enabling adoption of deep sub-micron chips for industrial applications Logic synthesis is an essential part of the modern digital IC design process in semi-conductor industry. This book discusses a logic synthesis technique called “rewiring” and its latest technical advancement in term of rewirability. Rewiring technique has surfaced in academic research since 1993 and there is currently no book available on the market which systematically and comprehensively discusses this rewiring technology. The authors cover logic transformation techniques with concentration on rewiring. For many decades, the effect of wiring on logic structures has been ignored due to an ideal view of wires and their negligible role in the circuit performance. However in today’s semiconductor technology wiring is the major player in circuit performance degeneration and logic synthesis engines can be improved to deal with this through wire-based transformations. This book introduces the automatic test pattern generation (ATPG)-based rewiring techniques, which are recently active in the realm of logic synthesis/verification of VLSI/SOC designs. Unique comprehensive coverage of semiconductor rewiring techniques written by leading researchers in the field Provides complete coverage of rewiring from an introductory to intermediate level Rewiring is explained as a flexible technique for Boolean logic synthesis, introducing the concept of Boolean circuit transformation and testing, with examples Readers can directly apply the described techniques to real-world VLSI design issues Focuses on the automatic test pattern generation (ATPG) based rewiring methods although some non-ATPG based rewiring methods such as graph based alternative wiring (GBAW), and “set of pairs of functions to be distinguished” (SPFD) based rewiring are also discussed A valuable resource for researchers and postgraduate students in VLSI and SoC design, as well as digital design engineers, EDA software developers, and design automation experts that specialize in the synthesis and optimization of logical circuits.

Vikas Mittal High Performance Polymers and Engineering Plastics Vikas Mittal High Performance Polymers and Engineering Plastics
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Vikas Mittal High Performance Polymers and Engineering Plastics


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15169.26 руб.

This book describes advances in synthesis, processing, and technology of environmentally friendly polymers generated from renewable resources. With contents based on a wide range of functional monomers and contributions from eminent researchers, this volume demonstrates the design, synthesis, properties and applications of plant oil based polymers, presenting an elaborate review of acid mediated polymerization techniques for the generation of green polymers. Chemical engineers are provided with state-of-the-art information that acts to further progress research in this direction.

Mark Peters Membrane Process Design Using Residue Curve Maps Mark Peters Membrane Process Design Using Residue Curve Maps
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Mark Peters Membrane Process Design Using Residue Curve Maps


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11697.89 руб.

Design and Synthesis of Membrane Separation Processes provides a novel method of design and synthesis for membrane separation. While the main focus of the book is given to gas separation and pervaporation membranes, the theory has been developed in such a way that it is general and valid for any type of membrane. The method, which uses a graphical technique, allows one to calculate and visualize the change in composition of the retentate (non-permeate) phase. This graphical approach is based on Membrane Residue Curve Maps. One of the strengths of this approach is that it is exactly analogous to the method of Residue Curve Maps that has proved so successful in distillation system synthesis and design.

John Tebby C. Alkynes in Cycloadditions John Tebby C. Alkynes in Cycloadditions
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John Tebby C. Alkynes in Cycloadditions


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14698.13 руб.

Acetylene systems present a new route to cyclic compounds as an alternative to more traditional methods employed in classical organic chemistry. The synthesis of cyclic structures based on acetylene systems has important applications in the formation of nanostructures, naturally occurring compounds and chemosensory materials for the design of nonlinear optics, electronic and photonic devices. Alkynes in Cycloadditions presents a modern review of regioselective synthesis of aromatic and non-aromatic carbocyclic and heterocyclic ring systems based primarily on [2+2+2] and [4+2] cycloadditions, and other reactions of acetylenic units including enediynes and enyne-allenes. Topics covered include: New strategies for the formation of aromatic and polynuclear hydrocarbons based on (Z)-hex-3-en-1,5-diyne and (Z)-hepta-1,2,4-triene-6-yne blocks. One-step synthesis of benzene derivatives, β-substituted naphthalenes and acenes by the cycloaromatization of enediynes and enyne-allenes by Bergman, Myers-Saito and Shmittel. Mechanisms of cycloaromatization resulting in the formation of fulvene and indene systems. Heterocyclization involving enyne-carbodiimides. New achievements in classical cycloaddition reactions such as the Diels-Alder condensation with acetylenic dienophiles and [2+2] cycloadditions with acetylene components Alkynes in Cycloadditions presents a comprehensive summary of the literature on methods for the synthesis of ring systems from acetylenes for academic researchers working in the fields of organic synthesis, physical organic chemistry, organometallic chemistry, catalysis, materials science, nanomaterials and biochemistry.

Vikas Mittal Renewable Polymers. Synthesis, Processing, and Technology Vikas Mittal Renewable Polymers. Synthesis, Processing, and Technology
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Vikas Mittal Renewable Polymers. Synthesis, Processing, and Technology


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15169.26 руб.

Presents the synthesis, technology and processing details of a large range of polymers derived from renewable resources It has been a long-term desire to replace polymers from fossil fuels with the more environmentally friendly polymers generated from renewable resources. Now, with the recent advancements in synthesis technologies and the finding of new functional monomers, research in this field has shown strong potential in generating better property polymers from renewable resources. A text describing these advances in synthesis, processing, and technology of such polymers not only provides the state-of-the-art information to researchers, but also acts to stimulate research in this direction. The contents are based on a wide range of functional monomers and the contributions are written by eminent researchers. Specifically Renewable Polymers: Demonstrates the design, synthesis, properties and applications of plant oil-based polymers Presents an elaborate review of acid mediated polymerization techniques for the generation of green polymers Details the production of polyhydroxyalkanoates (PHA) from olive oil based wastewater Describes the use of atom transfer radical polymerization (ATRP) techniques Reviews the renewable polymers derived from transgenic crop plants Provides an overview of a range of biomass-based polymers Concludes with the recent efforts and approaches exploiting the natural materials in developing drug delivery systems.

Ernesto Tomei Text-Atlas of Skeletal Age Determination. MRI of the Hand and Wrist in Children Ernesto Tomei Text-Atlas of Skeletal Age Determination. MRI of the Hand and Wrist in Children
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Ernesto Tomei Text-Atlas of Skeletal Age Determination. MRI of the Hand and Wrist in Children


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11994.57 руб.

The first complete textbook and atlas of the vitally important technique of bone age assessment utilizing MRI for children's hand and wrist This latest volume in the growing Wiley Current Clinical Imaging series is a must-have resource that collects, in a single volume, all that is currently known and applicable about the use of magnetic resonance imaging (MRI) for the assessment of bone age. Presented in two parts, Text-Atlas of Skeletal Age Determination: MRI of the Hand and Wrist in Children first focuses on the anatomic, social, and legal aspects of bone age, providing a concise overview of the use of bone age determination in medical, legal, and social systems.??It then covers the clinical use and application of MRI in assessing bone age. The book offers complete chapter coverage on endocrinology, puberty, and disorders of pubertal development; bone marrow maturation in healthy and diseased states; growth failure and pediatric inflammatory bowel disease; skeletal findings in neurometabolic disease, genetic disease, and pediatric oncology patients; and much more. Text-Atlas of Skeletal Age Determination provides: A comprehensive review of the medical, legal, and social aspects of bone age assessment An in-depth discussion of MRI as an alternative to the traditional ionizing radiation-based radiographic techniques for the assessment of bone age Complete guidelines for clinical application of these MRI-based techniques «Recipes» for replicating these techniques and applications for diverse patient populations Cutting-edge information prepared and presented by an international team of experts A superb collection of beautifully reproduced, high-quality images This is an ideal book for radiologists, pediatricians, family physicians, endocrinologists, and sports medicine physicians interested in skeletal development and bone age assessment.

Liming Xiu Nanometer Frequency Synthesis Beyond the Phase-Locked Loop Liming Xiu Nanometer Frequency Synthesis Beyond the Phase-Locked Loop
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Liming Xiu Nanometer Frequency Synthesis Beyond the Phase-Locked Loop


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10657.38 руб.

Introducing a new, pioneering approach to integrated circuit design Nanometer Frequency Synthesis Beyond Phase-Locked Loop introduces an innovative new way of looking at frequency that promises to open new frontiers in modern integrated circuit (IC) design. While most books on frequency synthesis deal with the phase-locked loop (PLL), this book focuses on the clock signal. It revisits the concept of frequency, solves longstanding problems in on-chip clock generation, and presents a new time-based information processing approach for future chip design. Beginning with the basics, the book explains how clock signal is used in electronic applications and outlines the shortcomings of conventional frequency synthesis techniques for dealing with clock generation problems. It introduces the breakthrough concept of Time-Average-Frequency, presents the Flying-Adder circuit architecture for the implementation of this approach, and reveals a new circuit device, the Digital-to-Frequency Converter (DFC). Lastly, it builds upon these three key components to explain the use of time rather than level to represent information in signal processing. Provocative, inspiring, and chock-full of ideas for future innovations, the book features: A new way of thinking about the fundamental concept of clock frequency A new circuit architecture for frequency synthesis: the Flying-Adder direct period synthesis A new electronic component: the Digital-to-Frequency Converter A new information processing approach: time-based vs. level-based Examples demonstrating the power of this technology to build better, cheaper, and faster systems Written with the intent of showing readers how to think outside the box, Nanometer Frequency Synthesis Beyond the Phase-Locked Loop is a must-have resource for IC design engineers and researchers as well as anyone who would like to be at the forefront of modern circuit design.

Shang-Cheng Hung Glycochemical Synthesis. Strategies and Applications Shang-Cheng Hung Glycochemical Synthesis. Strategies and Applications
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Shang-Cheng Hung Glycochemical Synthesis. Strategies and Applications


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14623.43 руб.

This book is a comprehensive and concise review on principles, strategies, and crucial advances in glycochemistry. It focuses on synthesis and practical applications and emphasizes state-of-the-art approaches to the assembly and design of sugars. • Provides detailed discussion on specific topics like oligosaccharide assembly and design of sugars, techniques in glycoconjugate preparation, multivalency, and carbohydrate-based drug design • Uses notable examples, like solution-based one-pot methods and automated methods for sugar assembly, to illustrate important concepts and advances in a rapidly emerging field • Discusses practical applications of carbohydrates, like medicine, therapeutics, drug and vaccine development

Marc Vandevelde Veterinary Neuropathology. Essentials of Theory and Practice Marc Vandevelde Veterinary Neuropathology. Essentials of Theory and Practice
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Marc Vandevelde Veterinary Neuropathology. Essentials of Theory and Practice


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8323.42 руб.

Introducing the theoretical and practical basics of veterinary neuropathology, this concise and well illustrated book is an essential basic diagnostic guide for pathologists, neurologists and diagnostic imaging specialists. It presents readers with strategies to deal with neuropathological problems, showing how to interpret gross and histological lesions using a systematic approach based on pattern recognition. It starts with an overview of the general principles of neuroanatomy, neuropathological techniques, basic tissue reaction patterns, and recognition of major lesion patterns. The book goes on to cover vascular diseases, inflammatory diseases, trauma, congenital malformations, metabolic-toxic diseases, neoplasia and degenerative diseases mainly of the central nervous system. In the respective chapters pathologists can quickly find information to support their daily diagnostic workup for both small and large domestic species. Based on the authors’ extensive diagnostic and post graduate teaching experience as well as the inclusion of MRI as it relates to neuropathology, this book also offers a comprehensive but basic analysis of veterinary neuropathology that neurologists and other MRI users will find very useful. • An essential manual for daily diagnostic work • Richly illustrated with high quality colour gross, histological and MRI images • Includes a section on the function and use of MRI (by Johann Lang, DECVDI) • Accompanied by a website presenting MRI sequences for interpretation and correlation with neuropathological findings edited by Johann Lang (University of Bern, Switzerland) and Eric Wiesner (University of California, Davis, USA)

Mrignayani Kotecha Magnetic Resonance Imaging in Tissue Engineering Mrignayani Kotecha Magnetic Resonance Imaging in Tissue Engineering
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Mrignayani Kotecha Magnetic Resonance Imaging in Tissue Engineering


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14623.43 руб.

Magnetic Resonance Imaging in Tissue Engineering provides a unique overview of the field of non-invasive MRI assessment of tissue engineering and regenerative medicine Establish a dialogue between the tissue-engineering scientists and imaging experts and serves as a guide for tissue engineers and biomaterial developers alike Provides comprehensive details of magnetic resonance imaging (MRI) techniques used to assess a variety of engineered and regenerating tissues and organs Covers cell-based therapies, engineered cartilage, bone, meniscus, tendon, ligaments, cardiovascular, liver and bladder tissue engineering and regeneration assessed by MRI Includes a chapter on oxygen imaging method that predominantly is used for assessing hypoxia in solid tumors for improving radiation therapy but has the ability to provide information on design strategies and cellular viability in tissue engineering regenerative medicine

Shinichi Itsuno Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis Shinichi Itsuno Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis
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Shinichi Itsuno Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis


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12909.43 руб.

This book reviews chiral polymer synthesis and its application to asymmetric catalysis. It features the design and use of polymer-immobilized catalysts and methods for their design and synthesis. Chapters cover peptide-catalyzed and enantioselective synthesis, optically-active polymers, and continuous flow processes. It collects recent advances in an important field of polymer and organic chemistry, with leading researchers explaining applications in academic and industry R & D.

Guo Zhongwu Carbohydrate-Based Vaccines and Immunotherapies Guo Zhongwu Carbohydrate-Based Vaccines and Immunotherapies
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Guo Zhongwu Carbohydrate-Based Vaccines and Immunotherapies


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12446.57 руб.

The fundamental science and the latest developments in carbohydrate-based vaccines The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments. With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances. Key topics covered by Carbohydrate-Based Vaccines and Immunotherapies include: Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi Using adjuvants to improve immunogenicity and/or immunological properties of vaccines Choosing and designing proper adjuvants for specific targets Abnormal carbohydrates expressed by tumors Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy Clinical trials results for synthetic cancer vaccines Glycoengineering of cell surface carborhydrates and its anticancer applications Using cell surface carbohydrates for disease diagnosis A single, convenient source of state-of-the-art information from leading authorities in the field, Carbohydrate-Based Vaccines and Immunotherapies is an essential reference for organic chemists and biochemists, academic researchers, and other students and professionals involved in vaccine design.

Elliott Ian Handbook of Small Animal MRI Elliott Ian Handbook of Small Animal MRI
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Elliott Ian Handbook of Small Animal MRI


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4977.98 руб.

Handbook of Small Animal MRI will help you make the most of one of the greatest advancements in veterinary practice in recent years, magnetic resonance imaging. Those using the services of mobile scanners dedicated to veterinary use, as well as those in practices with their own MRI machine, will benefit from this book. It provides a clear and comprehensive account of how this important diagnostic tool works. In addition this easy reference handbook provides guidance on the interpretation of images of common clinical conditions. The book includes: • An overview of the basic principles, explaining exactly how and why MRI works and how images are produced • Easy-to-understand diagrams to explain the theory of MRI • Safety procedures • A Glossary of terms • Over 100 annotated images of MRI scans to aid diagnosis • An additional atlas of normal anatomy for MRI interpretation Written by two pioneering experts in the field with a combined experience of over 20,000 MRI studies of veterinary patients. Suitable for small animal veterinarians and veterinary students. Ian Elliott trained as a Radiographer and first became involved with MRI in late 1980s. He has worked exclusively in MRI since 1991 and, following an extensive spell scanning human patients, helped pioneer the use of the technique in veterinary practice. Ian has been involved exclusively in veterinary MRI since 2000 and has scanned many thousands of cases during this time. He currently works for Burgess Diagnostics providing MRI services to veterinary surgeons throughout UK and Ireland. Geoff Skerritt is an RCVS Recognised Specialist in Veterinary Neurology, Diplomate of the European College of Veterinary Neurology and former President of the ECVN. In 1997 Geoff was one of the founders of VetMRI, the first mobile veterinary MRI facility in Europe. He is the founder and director of ChesterGates Animal Referral Hospital, a leading multi-discipline veterinary referral centre in the UK.

Pedro Martins Magnetoelectric Polymer-Based Composites. Fundamentals and Applications Pedro Martins Magnetoelectric Polymer-Based Composites. Fundamentals and Applications
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Pedro Martins Magnetoelectric Polymer-Based Composites. Fundamentals and Applications


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11998.84 руб.

The first book on this topic provides a comprehensive and well-structured overview of the fundamentals, synthesis and emerging applications of magnetoelectric polymer materials. Following an introduction to the basic aspects of polymer based magnetoelectric materials and recent developments, subsequent chapters discuss the various types as well as their synthesis and characterization. There then follows a review of the latest applications, such as memories, sensors and actuators. The book concludes with a look at future technological advances. An essential reference for entrants to the field as well as for experienced researchers.

Andrea Trabocchi Diversity-Oriented Synthesis. Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology Andrea Trabocchi Diversity-Oriented Synthesis. Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology
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Andrea Trabocchi Diversity-Oriented Synthesis. Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology


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11998.84 руб.

Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

John Talbot MRI in Practice John Talbot MRI in Practice
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John Talbot MRI in Practice


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4573.29 руб.

Since the first edition was published in 1993, MRI in Practice has become the standard text for radiographers, technologists, radiology residents, radiologists and even sales representatives on the subject of Magnetic Resonance Imaging (MRI). This text is essential reading on undergraduate and postgraduate MRI courses. Furthermore MRI in Practice has come to be known as the number one reference book and study guide in the areas of MR instrumentation, principles, pulse sequences, image acquisition, and imaging parameters for the advanced level examination for MRI offered by the American Registry for Radiologic Technologists (ARRT) in the USA. The book explains in clear terms the theory that underpins magnetic resonance so that the capabilities and operation of MRI systems can be fully appreciated and maximised. This fourth edition captures recent advances, and coverage includes: parallel imaging techniques and new sequences such as balanced gradient echo. Building on the success of the first three editions, the fourth edition has been fully revised and updated. The book now comes with a companion website at www.wiley.com/go/mriinpractice which hosts animated versions of a selection of illustrations in the book that are used on the MRI in Practice Course. These animations and accompanying text are aimed at helping the reader’s comprehension of some of the more difficult concepts. The website also hosts over 200 interactive self-assessment exercises to help the reader test their understanding. MRI in Practice features: Full color illustrations Logical presentation of the theory and applications of MRI A new page design A companion website at www.wiley.com/go/mriinpractice featuring interactive multiple choice questions, short answer questions PLUS animations of more complex concepts from the book For more information on the MRI in Practice Course and other learning resources by Westbrook and Talbot, please visit www.mrieducation.com

Jhuma Sadhukhan Biorefineries and Chemical Processes. Design, Integration and Sustainability Analysis Jhuma Sadhukhan Biorefineries and Chemical Processes. Design, Integration and Sustainability Analysis
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Jhuma Sadhukhan Biorefineries and Chemical Processes. Design, Integration and Sustainability Analysis


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9373.54 руб.

As the range of feedstocks, process technologies and products expand, biorefineries will become increasingly complex manufacturing systems. Biorefineries and Chemical Processes: Design, Integration and Sustainability Analysis presents process modelling and integration, and whole system life cycle analysis tools for the synthesis, design, operation and sustainable development of biorefinery and chemical processes. Topics covered include: Introduction: An introduction to the concept and development of biorefineries. Tools: Included here are the methods for detailed economic and environmental impact analyses; combined economic value and environmental impact analysis; life cycle assessment (LCA); multi-criteria analysis; heat integration and utility system design; mathematical programming based optimization and genetic algorithms. Process synthesis and design: Focuses on modern unit operations and innovative process flowsheets. Discusses thermochemical and biochemical processing of biomass, production of chemicals and polymers from biomass, and processes for carbon dioxide capture. Biorefinery systems: Presents biorefinery process synthesis using whole system analysis. Discusses bio-oil and algae biorefineries, integrated fuel cells and renewables, and heterogeneous catalytic reactors. Companion website: Four case studies, additional exercises and examples are available online, together with three supplementary chapters which address waste and emission minimization, energy storage and control systems, and the optimization and reuse of water. This textbook is designed to bridge a gap between engineering design and sustainability assessment, for advanced students and practicing process designers and engineers.

Ashutosh Tiwari Advanced 2D Materials Ashutosh Tiwari Advanced 2D Materials
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Ashutosh Tiwari Advanced 2D Materials


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16873.08 руб.

This book brings together innovative methodologies and strategies adopted in the research and developments of Advanced 2D Materials. Well-known worldwide researchers deliberate subjects on (1) Synthesis, characterizations, modeling and properties, (2) State-of-the-art design and (3) innovative uses of 2D materials including: Two-dimensional layered gallium selenide Synthesis of 2D boron nitride nanosheets The effects of substrates on 2-D crystals Electrical conductivity and reflectivity of models of some 2D materials Graphene derivatives in semicrystalline polymer composites Graphene oxide based multifunctional composites Covalent and non-covalent polymer grafting of graphene oxide Graphene-semiconductor hybrid photocatalysts for solar fuels Graphene based sensors Graphene composites from bench to clinic Photocatalytic ZnO-graphene hybrids Hydroxyapatite-graphene bioceramics in orthopaedic applications

Giacalone Francesco Catalytic Methods in Asymmetric Synthesis. Advanced Materials, Techniques, and Applications Giacalone Francesco Catalytic Methods in Asymmetric Synthesis. Advanced Materials, Techniques, and Applications
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Giacalone Francesco Catalytic Methods in Asymmetric Synthesis. Advanced Materials, Techniques, and Applications


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13298.39 руб.

This book covers advances in the methods of catalytic asymmetric synthesis and their applications. Coverage moves from new materials and technologies to homogeneous metal-free catalysts and homogeneous metal catalysts. The applications of several methodologies for the synthesis of biologically active molecules are discussed. Part I addresses recent advances in new materials and technologies such as supported catalysts, supports, self-supported catalysts, chiral ionic liquids, supercritical fluids, flow reactors and microwaves related to asymmetric catalysis. Part II covers advances and milestones in organocatalytic, enzymatic and metal-based mediated asymmetric synthesis, including applications for the synthesis of biologically active molecules. Written by leading international experts, this book consists of 16 chapters with 2000 References and illustrations of 560 schemes and figures.

Ravin Narain Engineered Carbohydrate-Based Materials for Biomedical Applications. Polymers, Surfaces, Dendrimers, Nanoparticles, and Hydrogels Ravin Narain Engineered Carbohydrate-Based Materials for Biomedical Applications. Polymers, Surfaces, Dendrimers, Nanoparticles, and Hydrogels
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Ravin Narain Engineered Carbohydrate-Based Materials for Biomedical Applications. Polymers, Surfaces, Dendrimers, Nanoparticles, and Hydrogels


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10890.75 руб.

This book addresses the need for a comprehensive book on the design, synthesis, and characterization of synthetic carbohydrate-based polymeric materials along with their biological applications. The first two chapters cover the synthesis and self-assembly of glycopolymers and different techniques for creating these synthetic polymers. Subsequent chapters account for the preparation of block copolymers, branched glycopolymers, glycosurfaces, glycodendrimers, cationic glycopolymers, bioconjugates, glyconanoparticles and hydrogels. While these chapters comprehensively review the synthetic and characterization methods of those carbohydrate-based materials, their biological applications are discussed in detail.


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Demonstrates techniques which will allow rewiring rates of over 95%, enabling adoption of deep sub-micron chips for industrial applications Logic synthesis is an essential part of the modern digital IC design process in semi-conductor industry. This book discusses a logic synthesis technique called “rewiring” and its latest technical advancement in term of rewirability. Rewiring technique has surfaced in academic research since 1993 and there is currently no book available on the market which systematically and comprehensively discusses this rewiring technology. The authors cover logic transformation techniques with concentration on rewiring. For many decades, the effect of wiring on logic structures has been ignored due to an ideal view of wires and their negligible role in the circuit performance. However in today’s semiconductor technology wiring is the major player in circuit performance degeneration and logic synthesis engines can be improved to deal with this through wire-based transformations. This book introduces the automatic test pattern generation (ATPG)-based rewiring techniques, which are recently active in the realm of logic synthesis/verification of VLSI/SOC designs. Unique comprehensive coverage of semiconductor rewiring techniques written by leading researchers in the field Provides complete coverage of rewiring from an introductory to intermediate level Rewiring is explained as a flexible technique for Boolean logic synthesis, introducing the concept of Boolean circuit transformation and testing, with examples Readers can directly apply the described techniques to real-world VLSI design issues Focuses on the automatic test pattern generation (ATPG) based rewiring methods although some non-ATPG based rewiring methods such as graph based alternative wiring (GBAW), and “set of pairs of functions to be distinguished” (SPFD) based rewiring are also discussed A valuable resource for researchers and postgraduate students in VLSI and SoC design, as well as digital design engineers, EDA software developers, and design automation experts that specialize in the synthesis and optimization of logical circuits.
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