lifespan development in action 1e



Overton Willis F. The Handbook of Life-Span Development, Cognition, Biology, and Methods Overton Willis F. The Handbook of Life-Span Development, Cognition, Biology, and Methods Новинка

Overton Willis F. The Handbook of Life-Span Development, Cognition, Biology, and Methods

11007.61 руб. Найти похожее
In the past fifty years, scholars of human development have been moving from studying change in humans within sharply defined periods, to seeing many more of these phenomenon as more profitably studied over time and in relation to other processes. The Handbook of Life-Span Development, Volume 1: Cognition, Biology, and Methods presents the study of human development conducted by the best scholars in the 21st century. Social workers, counselors and public health workers will receive coverage of of the biological and cognitive aspects of human change across the lifespan.
Free Shipping 10 PCS/LOT SP2526A-1EN 2526A-1E SOP8 NEW IN STOCK IC Free Shipping 10 PCS/LOT SP2526A-1EN 2526A-1E SOP8 NEW IN STOCK IC Новинка

Free Shipping 10 PCS/LOT SP2526A-1EN 2526A-1E SOP8 NEW IN STOCK IC

Free Shipping 10 PCS/LOT SP2526A-1EN 2526A-1E SOP8 NEW IN STOCK IC
Free Shipping 10 PCS/LOT SP2526A-1EN 2526A-1E SOP8 NEW IN STOCK IC Free Shipping 10 PCS/LOT SP2526A-1EN 2526A-1E SOP8 NEW IN STOCK IC Новинка

Free Shipping 10 PCS/LOT SP2526A-1EN 2526A-1E SOP8 NEW IN STOCK IC

Free Shipping 10 PCS/LOT SP2526A-1EN 2526A-1E SOP8 NEW IN STOCK IC
Shayne Gad Cox Development of Therapeutic Agents Handbook Shayne Gad Cox Development of Therapeutic Agents Handbook Новинка

Shayne Gad Cox Development of Therapeutic Agents Handbook

17612.17 руб. Найти похожее
A comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in characterizing potential drugs and their production and synthesis, Development of Therapeutic Agents Handbook gives professionals a basic tool to facilitate research and development within this challenging process. This comprehensive text brings together, in one resource, a compendium of concepts, approaches, methodologies, and limitations that need to be considered in the formulation of therapeutic agents across a range of therapeutic fields. Both a reference and a call to action for the pharmaceutical industry, Development of Therapeutic Agents Handbook examines recent innovations taking shape in the various medical disciplines involved in drug discovery, and shows why these advances need to be embraced universally among researchers to improve their solution strategies. Additional subject matter includes: Extensive coverage and in-depth look into novel treatments and therapeutics Discussion of hot topics like new drugs and nutraceuticals, the discovery and development of vaccines, cancer therapeutics, and market overviews Coverage of therapeutic drug development for specific disease areas, such as cardiology, oncology, breast cancer, and kidney diseases As research in biology, chemistry, medicine, and technology rapidly progresses, it is becoming increasingly important for medical researchers to maintain an up-to-date knowledge base of emerging trends directing promising new therapies. Development of Therapeutic Agents Handbook serves this purpose, acting as both a one-stop reference rich in valid science, and a tool to carve out new pathways in the pursuit of bringing safer and more effective drugs to the marketplace.
Julia Syanova Game of Tag. Fantasy Julia Syanova Game of Tag. Fantasy Новинка

Julia Syanova Game of Tag. Fantasy

«Game of Tag» – a story for fans of fantasy and twisted plots. The action takes place in the middle of the XXI century in the space of reality and the game. The world of Julia Syanovoy is saturated with images of Grand battles, intertwined with the development of action in a scientific Institute. To get into the game against my will – not so bad, you need to get out of it. Dynamic storytelling keeps the reader’s attention throughout the story.
Litwin Virginia Flow Cytometry in Drug Discovery and Development Litwin Virginia Flow Cytometry in Drug Discovery and Development Новинка

Litwin Virginia Flow Cytometry in Drug Discovery and Development

This book covers the unique application of flow cytometry in drug discovery and development. The first section includes two introductory chapters, one on flow cytometry and one on biomarkers, as well as a chapter on recent advances in flow cytometry. The second section focuses on the unique challenges and added benefits associated with the use of flow cytometry in the drug development process. The third section contains a single chapter presenting an in depth discussion of validation considerations and regulatory compliance issues associated with drug development.
Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena Новинка

Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena

A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs and robotics and other emerging methodologies for LBAs. Highlights include: A general discussion of challenges and proven approaches in the development of ligand-binding assays More detailed examination of characteristics of these assays when applied to support of pharmacokinetic and toxicokinetic studies of compounds at different stages in the discovery or development timeline A concise, but detailed, discussion of validation of ligand-binding assays for macromolecules A practical approach to «fit-for-purpose» validation of assays for biomarkers, those molecules receiving increased attention as potentially demonstrating that the target chosen in discovery is being modulated by the candidate therapeutic, both in nonclinical and clinical studies Written by a team of world-recognized authorities in the field, Ligand-Binding Assays provides key information to a broad range of practitioners, both in the pharmaceutical and allied industries and in related contract research organizations and academic laboratories and, perhaps, even in the field of diagnostics and clinical chemistry.
Jan Pronk P. Catalysing Development? A Debate on Aid Jan Pronk P. Catalysing Development? A Debate on Aid Новинка

Jan Pronk P. Catalysing Development? A Debate on Aid

This volume presents a state-of-the-art debate on the controversial topic of development aid. The contributors are all experts in the field of international development. Presents some challenging conclusions about the role that aid plays in catalysing, or stifling, development. Represents a wide range of different analytical perspectives.
Паучи Hill's Science Plan Healthy Development Kitten Seafish Chunks in Gravy с морской рыбой кусочки в подливке для котят 85г (2113) Паучи Hill's Science Plan Healthy Development Kitten Seafish Chunks in Gravy с морской рыбой кусочки в подливке для котят 85г (2113) Новинка

Паучи Hill's Science Plan Healthy Development Kitten Seafish Chunks in Gravy с морской рыбой кусочки в подливке для котят 85г (2113)

Hill's Science Plan with Seafish – точно сбалансированное питание для удовлетворения индивидуальных потребностей котенка, которое исключает любой недостаток или избыток питательных веществ. Полезные качества корма: - поддержание здоровья иммунной системы (благодаря антиоксидантам с клинически подтвержденным эффектом), - нежное здоровое пищеварение (благодаря высокому качеству ингредиентов), - оптимальное развитие головного мозга, повышение скорости реакции и внимательности (благодаря Омега-3 жирным кислотам (Дгк)). Ингредиенты: С Океанической рыбой: курица, свинина, концентрат горохового протеина, лосось (4%), крахмал тапиоки, минералы, сухое цельное яйцо, кукурузный крахмал, целлюлоза, сухой белок, декстроза, подсолнечное масло, рыбий жир, Dl-метионин, витамины, таурин, микроэлементы и бета-каротин. Окрашено натуральной карамелью. Информация с сайта производителя Hill's Science Plan with Seafish – точно сбалансированное питание для удовлетворения индивидуальных потребностей котенка, которое исключает любой недостаток или избыток питательных веществ. Полезные качества корма: - поддержание здоровья иммунной системы (благодаря антиоксидантам с клинически подтвержденным эффектом), - нежное здоровое пищеварение (благодаря высокому качеству ингредиентов), - оптимальное развитие головного мозга, повышение скорости реакции и внимательности (благодаря Омега-3 жирным кислотам (Дгк)). Ингредиенты: С Океанической рыбой: курица, свинина, концентрат горохового протеина, лосось (4%), крахмал тапиоки, минералы, сухое цельное яйцо, кукурузный крахмал, целлюлоза, сухой белок, декстроза, подсолнечное масло, рыбий жир, Dl-метионин, витамины, таурин, микроэлементы и бета-каротин. Окрашено натуральной карамелью. Информация с сайта производителя
Brian Wilson Professional SharePoint 2013 Development Brian Wilson Professional SharePoint 2013 Development Новинка

Brian Wilson Professional SharePoint 2013 Development

Thorough coverage of development in SharePoint 2013 A team of well-known Microsoft MVPs joins forces in this fully updated resource, providing you with in-depth coverage of development tools in the latest iteration of the immensely popular SharePoint. From building solutions to building custom workflow and content management applications, this book shares field-tested best practices on all aspect of SharePoint 2013 development. Offers a thorough look at Windows Azure and SharePoint 2013 Includes new chapters on Application Life Cycle Management, developing apps in SharePoint, and building PerformancePoint Dashboards in SharePoint Professional SharePoint 2013 Development is an essential SharePoint developer title.
Паучи Hill's Science Plan Healthy Development Kitten Chicken Tender Chunks in Gravy с курицей кусочки в подливке для котят 85г (2112) Паучи Hill's Science Plan Healthy Development Kitten Chicken Tender Chunks in Gravy с курицей кусочки в подливке для котят 85г (2112) Новинка

Паучи Hill's Science Plan Healthy Development Kitten Chicken Tender Chunks in Gravy с курицей кусочки в подливке для котят 85г (2112)

Hill’s Science Plan Tender Chunks Chicken – точно сбалансированное питание для удовлетворения индивидуальных потребностей котенка, которое исключает любой недостаток или избыток питательных веществ. Полезные качества корма: - поддержание здоровья иммунной системы (благодаря антиоксидантам с клинически подтвержденным эффектом), - нежное здоровое пищеварение (благодаря высокому качеству ингредиентов), - оптимальное развитие головного мозга, повышение скорости реакции и внимательности (благодаря Омега-3 жирным кислотам (Дгк)). Ингредиенты: Курица: курица (32%), свинина, концентрат горохового протеина, крахмал тапиоки, минералы, лосось, пшеничная мука, сухой белок, сухое цельное яйцо, целлюлоза, кукурузный крахмал, декстроза, рыбий жир, подсолнечное масло, Dl-метионин, таурин, витамины и микроэлементы, бета-каротин. Окрашено натуральной карамелью. Информация с сайта производителя Hill’s Science Plan Tender Chunks Chicken – точно сбалансированное питание для удовлетворения индивидуальных потребностей котенка, которое исключает любой недостаток или избыток питательных веществ. Полезные качества корма: - поддержание здоровья иммунной системы (благодаря антиоксидантам с клинически подтвержденным эффектом), - нежное здоровое пищеварение (благодаря высокому качеству ингредиентов), - оптимальное развитие головного мозга, повышение скорости реакции и внимательности (благодаря Омега-3 жирным кислотам (Дгк)). Ингредиенты: Курица: курица (32%), свинина, концентрат горохового протеина, крахмал тапиоки, минералы, лосось, пшеничная мука, сухой белок, сухое цельное яйцо, целлюлоза, кукурузный крахмал, декстроза, рыбий жир, подсолнечное масло, Dl-метионин, таурин, витамины и микроэлементы, бета-каротин. Окрашено натуральной карамелью. Информация с сайта производителя
S. P. Peca Real Estate Development and Investment. A Comprehensive Approach S. P. Peca Real Estate Development and Investment. A Comprehensive Approach Новинка

S. P. Peca Real Estate Development and Investment. A Comprehensive Approach

Real Estate Development and Investment A Comprehensive Approach Written by real estate industry veteran Stephen Peca, this timely guide skillfully outlines the various phases of the real estate development process and addresses some of the most important issues associated with this discipline. Using numerous illustrations and anecdotes, this book takes you through the development process, from historical considerations and idea formulation to financial feasibility and asset disposition, while covering the entire cycle of real estate development for various property types. Topics touched upon throughout these pages include: The key factors affecting demand for different land uses and development The interaction of market research, financing, planning, contract negotiation, marketing, leasing, and property management The need for universal, current, and broad knowledge The importance of ethics in the development process The role of different professionals and companies involved in the development process Environmental considerations in real estate development And much more Filled with in-depth insights and practical advice, this reliable resource will help you gain a firm understanding of the functional skills necessary to be successful in this field and familiarize you with several often-overlooked-but essential aspects of commercial real estate development.
Ron Forlee Australian Residential Property Development for Investors Ron Forlee Australian Residential Property Development for Investors Новинка

Ron Forlee Australian Residential Property Development for Investors

The all-in-one reference for the new residential real estate investor Australian Residential Property Development for Investors is the practical, step-by-step guide for beginners and experienced investors in the real estate and construction industries. From site selection to sale, this book walks you through each phase of the property development process to show you how careful planning can considerably enhance returns on your investment. This practical and effective guide features the latest information on development economics, the impact of electronic media, new cost-effective building methods, and a collection of case studies that illustrate these ideas in action. With a focus on practical outcomes, you'll learn how to approach the property from an investor's perspective to minimize risk and maximize returns. Australians have long had a love affair with residential property. We have one of the highest rates of home ownership in the world, and investing in residential real estate is a popular route to financial security. This book shows you how to make property development feasible within your time and budget constraints, netting you more profit and less headache. Select the site with the most profit potential, and find dependable financing Work more effectively with contractors, councils, consultants, and solicitors Apply standard monitoring and risk management techniques to your investment Cost and market the improved property appropriately to target the right buyers Newcomers are understandably overwhelmed by zoning, financing, construction, marketing, and everything else that goes into property development, frequently resulting in mistakes and missed profit. For the fledgling developer hoping to make the most of a new investment, Australian Residential Property Development for Investors provides all-in-one reference, with proven systems, techniques, and tools.
Kubiak Jacek Z. Xenopus Development Kubiak Jacek Z. Xenopus Development Новинка

Kubiak Jacek Z. Xenopus Development

Frogs from the genus Xenopus have long been used as model organisms in basic and biomedical research. These frogs have helped unlock key fundamental developmental and cellular processes that have led to important scientific breakthroughs and have had practical application in embryology, cancer research and regenerative medicine. Xenopus Development is a vital resource on the biology and development of these key model organisms, and will be a great tool to researchers using these frogs in various disciplines of biological science. Xenopus Development is divided into four sections, the first three highlight key processes in Xenopus development from embryo to metamophosis. These sections focus on the cellular processes, organogenesis and embryo development. The final section highlights novel techniques and approaches being used in Xenopus research. Providing thorough and detailed coverage, Xenopus Development, will be a timely and welcome volume for those working in cell and molecular biology, genetics, developmental biology and biomedical research. Provides broad overview of the developmental biology of both Xenopus laevis and Xenopus tropicalis Explores cellular to systems development in key biomedical model organisms Timely synthesis of the field of Xenopus biology Highlights key biomedical and basic biological findings unlocked by Xenopus
Stanley Weiss I. Product and Systems Development. A Value Approach Stanley Weiss I. Product and Systems Development. A Value Approach Новинка

Stanley Weiss I. Product and Systems Development. A Value Approach

A thorough treatment of product and systems development in terms of value to all stakeholders Product and Systems Development compiles more than twenty years of research and practice from a value perspective, from vision and marketing to design, manufacturing, delivery, operations, and maintenance. It defines stakeholder value and identifies specific stakeholders in the product and system development process; covers best practices in development; and examines systems engineering, current industry views, and the life cycle of a value stream. Featuring appendices written by professionals in the field on topics such as Design Structure Matrices, Lean Enablers for systems engineering, and MDAO and simulations, this indispensable guide: Explains why stakeholders' values can hold the key to fulfillment or defeat of the developer's vision Emphasizes the succession of value-contributing practices and tools that form a framework for development success Integrates the technical, productivity, and customer/end-user elements in product and system development Uses more than 100 tables and figures to illustrate the above processes, as well as corollary elements of risk, failure analysis, and fault-tolerant design Includes numerous case studies and links to online material Product and Systems Development is an excellent coursebook for senior and graduate students in aerospace, mechanical, civil, electrical, and material engineering, as well as management science and engineering. It is also a useful reference for practicing engineers in a variety of technology-based industries.
Urban Laszlo Predictive ADMET. Integrated Approaches in Drug Discovery and Development Urban Laszlo Predictive ADMET. Integrated Approaches in Drug Discovery and Development Новинка

Urban Laszlo Predictive ADMET. Integrated Approaches in Drug Discovery and Development

This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so that pharmaceutical scientists can diagnose ADMET problems and present appropriate recommendations to move drug discovery programs forward. The book introduces the current clinical practice for drug discovery and development along with the impact on early risk assessment; consolidates the tools and models to intelligently integrate existing in silico, in vitro and in vivo ADMET data; and demonstrates successful cases and lessons learned from real drug discovery and development. In short, it is a book aimed to provide a practical road map for drug discovery and development scientists to generate efficacious and safe drugs for unmet medical needs.
Mitchell Cayen N. Early Drug Development. Strategies and Routes to First-in-Human Trials Mitchell Cayen N. Early Drug Development. Strategies and Routes to First-in-Human Trials Новинка

Mitchell Cayen N. Early Drug Development. Strategies and Routes to First-in-Human Trials

11447.91 руб. Найти похожее
The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials guides drug development organizations in preparing and submitting an Investigational New Drug (IND) application. By explaining the nuts and bolts of preclinical development activities and their interplay in effectively identifying successful clinical candidates, the book helps pharmaceutical scientists determine what types of discovery and preclinical research studies are needed in order to support a submission to regulatory agencies.
Accessory Shield for Arduino Development Accessory Shield for Arduino Development Новинка

Accessory Shield for Arduino Development

12620.09 руб. Найти похожее
[Wholesale] 20pcs Accessory Shield for Arduino Development Accessories IN One Board
A. Gould Lawrence Statistical Methods for Evaluating Safety in Medical Product Development A. Gould Lawrence Statistical Methods for Evaluating Safety in Medical Product Development Новинка

A. Gould Lawrence Statistical Methods for Evaluating Safety in Medical Product Development

This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each chapter provides sufficient detail to the reader to undertake the design and analysis of experiments at various stages of product development, including comprehensive references to the relevant literature. Provides a guide to statistical methods and application in medical product development Assists readers in undertaking design and analysis of experiments at various stages of product development Features case studies throughout the book, as well as, SAS and R code
ESP8266 ESP-12E Development Board Module ESP8266 ESP-12E Development Board Module Новинка

ESP8266 ESP-12E Development Board Module

ESP8266 ESP-12E Development Board Module Compatible with Arduino IDE w/ Built-in CH340G Driver IC
Паучи Hill's Science Plan Healthy Development Kitten Turkey Chunks in Gravy с индейкой кусочки в подливке для котят 85г (2114) Паучи Hill's Science Plan Healthy Development Kitten Turkey Chunks in Gravy с индейкой кусочки в подливке для котят 85г (2114) Новинка

Паучи Hill's Science Plan Healthy Development Kitten Turkey Chunks in Gravy с индейкой кусочки в подливке для котят 85г (2114)

Hill's Science Plan with Turkey - точно сбалансированное питание для удовлетворения индивидуальных потребностей котенка, которое исключает любой недостаток или избыток питательных веществ. Полезные качества корма: - поддержание здоровья иммунной системы (благодаря антиоксидантам с клинически подтвержденным эффектом), - нежное здоровое пищеварение (благодаря высокому качеству ингредиентов), - оптимальное развитие головного мозга, повышение скорости реакции и внимательности (благодаря Омега-3 жирным кислотам (Дгк)). Ингредиенты: С Индейкой: курица, свинина, индейка (4%), концентрат горохового протеина, крахмал тапиоки, пшеничная мука, целлюлоза, сухое цельное яйцо, сухой белок, кукурузный крахмал, декстроза, рыбий жир, подсолнечное масло, Dl-метионин, витамины, таурин, микроэлементы и бета-каротин. Окрашено натуральной карамелью. Информация с сайта производителя Hill's Science Plan with Turkey - точно сбалансированное питание для удовлетворения индивидуальных потребностей котенка, которое исключает любой недостаток или избыток питательных веществ. Полезные качества корма: - поддержание здоровья иммунной системы (благодаря антиоксидантам с клинически подтвержденным эффектом), - нежное здоровое пищеварение (благодаря высокому качеству ингредиентов), - оптимальное развитие головного мозга, повышение скорости реакции и внимательности (благодаря Омега-3 жирным кислотам (Дгк)). Ингредиенты: С Индейкой: курица, свинина, индейка (4%), концентрат горохового протеина, крахмал тапиоки, пшеничная мука, целлюлоза, сухое цельное яйцо, сухой белок, кукурузный крахмал, декстроза, рыбий жир, подсолнечное масло, Dl-метионин, витамины, таурин, микроэлементы и бета-каротин. Окрашено натуральной карамелью. Информация с сайта производителя
Accessory Shield for Arduino Development Accessory Shield for Arduino Development Новинка

Accessory Shield for Arduino Development

Accessory Shield for Arduino Development Accessories IN One Board
HPLC Method Development for Pharmaceuticals: Volume 8 HPLC Method Development for Pharmaceuticals: Volume 8 Новинка

HPLC Method Development for Pharmaceuticals: Volume 8

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory; Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities); Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase.
Preston Smith G. Flexible Product Development. Building Agility for Changing Markets Preston Smith G. Flexible Product Development. Building Agility for Changing Markets Новинка

Preston Smith G. Flexible Product Development. Building Agility for Changing Markets

In this landmark book, Preston Smith attributes the recent decline in innovation to pressure from financial markets that drives management toward rigid development approaches such as phased development processes, Six Sigma, and project office. These processes have unintentionally (but effectively) made changes during development more difficult, disruptive, and expensive, while the need for change continues at an accelerating pace. Flexible Product Development is a hands-on resource that provides the tools and strategies needed to restore flexibility to any organization and remove the obstacles that stand in the way of responsive new product development. Preston Smith introduces approaches that can enhance development process flexibility by creating and maintaining development options, delaying decisions, and, in general, reducing the cost of change. Step-by-step, he explains the basics of flexible product development, provides a broad array of flexibility-enhancing tools, and guides the reader in modifying the organization?s values to embrace this new way of operating.
Kenneth Kahn B. The PDMA Handbook of New Product Development Kenneth Kahn B. The PDMA Handbook of New Product Development Новинка

Kenneth Kahn B. The PDMA Handbook of New Product Development

New Product Development is one of the most important challenges facing organizations today. The Product Development and Management Association (PDMA) Handbook of New Product Development 3rd Edition provides an exceptional review of cutting edge topics for both new and experienced product development leaders. It offers a comprehensive and updated guide to the practices, processes and tools critical to achieving and sustaining new product/service development success in today’s world, delivering valuable information about the fundamentals as well as emerging practices such as venturing, virtual product development and the use of social media in NPD. As the premier global advocate for professionals and organizations working in the fields of new product/service development, PDMA has assembled in the Handbook unique content on the critical aspects of product development success including its 2012 Best Practices Research, Lessons Learned from its Outstanding Corporate Innovator Award Winners and keys to success from organizations with proven innovation track records. The 3rd Edition is an essential reference for anyone with responsibility for product development activities, from novices looking for fundamentals to experts seeking insights on emerging concepts, and is relevant for all functions and all product/service industries.
Ge Wu Assay Development. Fundamentals and Practices Ge Wu Assay Development. Fundamentals and Practices Новинка

Ge Wu Assay Development. Fundamentals and Practices

Essential principles and practice of assay development The first comprehensive, integrated treatment of the subject, Assay Development: Fundamentals and Practices covers the essentials and techniques involved in carrying out an assay project in either a biotechnology/drug discovery setting or a platform setting. Rather than attempting comprehensive coverage of all assay development technologies, the book introduces the most widely used assay development technologies and illustrates the art of assay development through a few commonly encountered biological targets in assay development (e.g., proteases, kinases, ion channels, and G protein-coupled receptors). Just enough biological background for these biological targets is provided so that the reader can follow the logics of assay development. Chapters discuss: The basics of assay development, including foundational concepts and applications Commonly used instrumental methods for both biochemical assays and cell-based assays Assay strategies for protein binding and enzymatic activity Cell-based assays High-throughput screening An in-depth study of the now popular Caliper's off-chip kinase assay provides an instructive, real-world example of the assay development process.
Flanagan Constance A. Youth Civic Development: Work at the Cutting Edge. New Directions for Child and Adolescent Development, Number 134 Flanagan Constance A. Youth Civic Development: Work at the Cutting Edge. New Directions for Child and Adolescent Development, Number 134 Новинка

Flanagan Constance A. Youth Civic Development: Work at the Cutting Edge. New Directions for Child and Adolescent Development, Number 134

Take a cutting edge look at the civic engagement of young people. Increasingly recognized as an important feature of democratic functioning in communities, it has also become clear that the civic domain is indispensable as a context for understanding human development processes. This volume proposes the following central theses in relation to youth civic development: It is rooted in the realities of young people’s everyday lives. It is collectively constructed. It raises questions about the principles, values, and relationships that bind people together in societies. It raises questions about power and justice. Youth civic development pushes the field to focus on the social issues with which younger generations are grappling and the identities they are constructing—issues that also are shaped by structural inequalities and by the collective actions of youth. The volume builds on themes of agency and assets from the field of positive youth development and points to ways that the critical analysis and engagement of young people in their society can contribute to social change. This is the 134th volume in this series. Its mission is to provide scientific and scholarly presentations on cutting edge issues and concepts in child and adolescent development. Each volume focuses on a specific new direction or research topic and is edited by experts on that topic.
British Nutrition Foundation Nutrition and Development. Short and Long Term Consequences for Health British Nutrition Foundation Nutrition and Development. Short and Long Term Consequences for Health Новинка

British Nutrition Foundation Nutrition and Development. Short and Long Term Consequences for Health

This Task Force report reviews the evidence that the seeds of many adult diseases are sown in utero and in infancy. The report, written by experts in the field, summarises current knowledge in this area. It illustrates how early life nutrition can bring about changes in organ development and function, thus programming risk of disease in adult life. It also considers what might be done in early life to reduce the burden of future ill health. Nutrition and Development: Short- and Long-Term Consequences for Health includes chapters on the history of this topic area, normal growth and development, and current recommendations and practice in relation to nutrition and diet in early life. Chapters exploring the possible mechanisms and pathways of critical windows for development cover the effects of diet and nutrition in early life on organ and skeletal development, the role of sex hormones in programming disease susceptibility, the establishment of gastrointestinal microbiota, and the impact of early life nutrition on cognitive and neurological development. This new report: • describes how development occurs and explores how changes in the fetal and postnatal environment, such as over- or under-nutrition, can result in permanent alterations in function; • explains how diet and nutrition in early life can affect risk of adult disease, with specific chapters on allergic disease and asthma, bone health, cancer, cardiovascular disease, cognitive function, diabetes and obesity; • includes a summary of the key points, as well as recommendations in each chapter to help fill the gaps in our knowledge; • provides an overview of the main messages in a practical question and answer format suitable for lay readers. Nutrition and Development is an important information resource for those involved in research and teaching in the health sciences sector and is also of value to those involved in making decisions about health policy. It will be of interest to a broad range of health professionals, the food industry and those who write and broadcast about the effects of food on health.
Natanya Civjan Chemical Biology. Approaches to Drug Discovery and Development to Targeting Disease Natanya Civjan Chemical Biology. Approaches to Drug Discovery and Development to Targeting Disease Новинка

Natanya Civjan Chemical Biology. Approaches to Drug Discovery and Development to Targeting Disease

An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including: The design, development, and optimization of drug candidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models as pharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV to schizophrenia Chemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences.
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Tom Beeckman Annual Plant Reviews, Root Development Tom Beeckman Annual Plant Reviews, Root Development Новинка

Tom Beeckman Annual Plant Reviews, Root Development

16602.61 руб. Найти похожее
Root Development is an extremely exciting new title in Blackwell Publishing's Annual Plant Reviews Series (Series Editor Profesor Jeremy Roberts). The book consists of contributions from author groups based at many of the World's formeost laboratories working in the root development area. The book's editor Tom Beeckman, himself very well known and respected for his work in this area, has drawn together an exceptional set of core cutting edge reviews of the subject, providing a state of the art reference tool for all those researching in this area.
Пеналы Tiger Enterprise Пенал для мальчика Сosmic collection Dino in action 19x11x5 см Пеналы Tiger Enterprise Пенал для мальчика Сosmic collection Dino in action 19x11x5 см Новинка

Пеналы Tiger Enterprise Пенал для мальчика Сosmic collection Dino in action 19x11x5 см

Tiger Enterprise Пенал для мальчика Сompact collection, Dino in action. Пенал на молнии без наполнения, 2 отделения, на 2-х молниях. Рассчитан на наполнение 20 предметами. Размер: 19 x 11 x 5 см в сложенном виде.
Seth Schwartz J. Identity Around the World. New Directions for Child and Adolescent Development, Number 138 Seth Schwartz J. Identity Around the World. New Directions for Child and Adolescent Development, Number 138 Новинка

Seth Schwartz J. Identity Around the World. New Directions for Child and Adolescent Development, Number 138

Examine the structure and context of identity development in a number of different countries: Belgium, the Netherlands, Germany, Sweden, Italy, China, and Japan. While some identity development proceeds in much the same way across national contexts, this issue suggests that there are important nuances in the ways in which identity unfolds in each country. Macrocultural forces, such as permissiveness in Sweden, collective guilt in Germany, and filial piety in China, direct the identity development process in important ways. Expectations regarding obligations and ties to family also direct the identity development process differently in many of the countries included in this volume—such as extended co-residence with parents in Italy, lifelong obligations to follow parents' wishes in China, and democratic independence in Sweden. The various countries are compared and contrasted against the United States, where much of the early identity research was conducted. The volume also reviews specific identity challenges facing immigrant and ethnic-minority individuals in countries that receive large numbers of immigrants—Germany, Sweden, Belgium, the Netherlands, and Italy—and suggests many future directions for identity research in various parts of the world. This is the 138th volume in this series. Its mission is to provide scientific and scholarly presentations on cutting edge issues and concepts in child and adolescent development. Each volume focuses on a specific new direction or research topic and is edited by experts on that topic.
Surapaneni Sekhar ADME-Enabling Technologies in Drug Design and Development Surapaneni Sekhar ADME-Enabling Technologies in Drug Design and Development Новинка

Surapaneni Sekhar ADME-Enabling Technologies in Drug Design and Development

12076.92 руб. Найти похожее
A comprehensive guide to cutting-edge tools in ADME research The last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of available technologies, giving readers the information they need to choose the right tool for a given application, a key requisite for obtaining favorable results in a timely fashion for regulatory filings. With over thirty contributed chapters by an international team of experts, the book provides: A thorough examination of current tools, covering both electronic/mechanical technologies and biologically based ones Coverage of applications for each technology, including key parameters, optimal conditions for intended results, protocols, and case studies Detailed discussion of emerging tools and techniques, from stem cells and genetically modified animal models to imaging technologies Numerous figures and diagrams throughout the text Scientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical science will find ADME-Enabling Technologies in Drug Design and Development an invaluable guide to the entire drug development process, from discovery to regulatory issues.
Lu Chuang Enzyme Inhibition in Drug Discovery and Development. The Good and the Bad Lu Chuang Enzyme Inhibition in Drug Discovery and Development. The Good and the Bad Новинка

Lu Chuang Enzyme Inhibition in Drug Discovery and Development. The Good and the Bad

14086.59 руб. Найти похожее
The science and applied approaches of enzyme inhibition in drug discovery and development Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development. With chapters written by over fifty leading experts in their fields, Enzyme Inhibition in Drug Discovery and Development fosters a cross-fertilization of pharmacology, drug metabolism, pharmacokinetics, and toxicology by understanding the «good» inhibitions—desirable pharmacological effects—and «bad» inhibitions—drug–drug interactions and toxicity. The book discusses: The drug discovery process, including drug discovery strategy, medicinal chemistry, analytical chemistry, drug metabolism, pharmacokinetics, and safety biomarker assessment The manipulations of drug metabolizing enzymes and transporters as well as the negative consequences, such as drug–drug interactions The inhibition of several major drug target pathways, such as the GPCR pathway, the NFkB pathway, and the ion channel pathway Through this focused, single-source reference on the fundamentals of drug discovery and development, researchers in drug metabolism and pharmacokinetics (DMPK) will learn and appreciate target biology in drug discovery; discovery biologists and medicinal chemists will also broaden their understanding of DMPK.
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Fivush Robyn The Wiley Handbook on the Development of Children's Memory Fivush Robyn The Wiley Handbook on the Development of Children's Memory Новинка

Fivush Robyn The Wiley Handbook on the Development of Children's Memory

26418.25 руб. Найти похожее
This all-embracing Handbook on the Development of Children’s Memory represents the first place in which critical topics in memory development are covered from multiple perspectives, from infancy through adolescence. Forty-four chapters are written by experienced researchers who have influenced the field. Edited by two of the world’s leading experts on the development of memory Discusses the importance of a developmental perspective on the study of memory The first ever handbook to bring together the world’s leading academics in one reference guide Each section has an introduction written by one of the Editors, who have also written an overall introduction that places the work in historical and contemporary contexts in cognitive and developmental psychology 2 Volumes
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Michael E. Lamb The Role of the Father in Child Development Michael E. Lamb The Role of the Father in Child Development Новинка

Michael E. Lamb The Role of the Father in Child Development

The Definitive reference on the important role fathers play in child development today Edited by Dr. Michael Lamb—the recognized authority on the role of fathers in child development, The Role of the Father in Child Development, Fifth Edition brings together contributions from international experts on each subject to provide a thorough and current summary of the state of fatherhood across cultures, classes, economic systems, and family formations. This classic guide offers a single-source reference for the most recent findings and beliefs related to fathers and fatherhood. This thoroughly updated new edition provides the latest material on topics such as: The effects of divorce Fathers from low-income backgrounds Stepfathers’ lives: exploring social context and interpersonal complexity Social policy Gay fathers Fatherhood and masculinity The definitive book on when, why, and how fathers matter to their children and families, The Role of the Father in Child Development, Fifth Edition is an essential reference for all mental health professionals who endeavor to understand and support fathers in becoming positive influences in their children’s development.
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Julie Scholes Developing Expertise in Critical Care Nursing Julie Scholes Developing Expertise in Critical Care Nursing Новинка

Julie Scholes Developing Expertise in Critical Care Nursing

Developing Expertise in Critical Care Nursing examines the development of professional expertise in critical care nursing, based on extensive research in clinical practice. It offers a repertoire of learning and assessment methods that enable practitioners to grow their own expertise and foster developments in others. Developing Expertise in Critical Care Nursing will be of interest to practitioners who aspire to advanced level practice in critical care and to all who facilitate this process. It debates the characteristics of expert practice and practice development and examines the acquisition of core skills, and career development in critical care using a role transition model.
Collected Papers In Theoretical Economics: Development, Markets, And Institutions Collected Papers In Theoretical Economics: Development, Markets, And Institutions Новинка

Collected Papers In Theoretical Economics: Development, Markets, And Institutions

Book DescriptionThe field of development economics has witnessed major changes over the last tow or three decades. From being a largely descriptive discipline, it has now become much more rigorous and theoretically well-founded. Kaushik Basu's work has played a significant role in this transformation of development economics, and the present book is a collection of his major papers in the field.
Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development Новинка

Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development

RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects.
Ekins Sean The Agile Approach to Adaptive Research. Optimizing Efficiency in Clinical Development Ekins Sean The Agile Approach to Adaptive Research. Optimizing Efficiency in Clinical Development Новинка

Ekins Sean The Agile Approach to Adaptive Research. Optimizing Efficiency in Clinical Development

Apply adaptive research to improve results in drug development The pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how adaptive research, using already-available tools and techniques, can enable the industry to streamline clinical trials and reach decision points faster and more efficiently. With a wealth of real-world cases and examples, author Michael Rosenberg gives readers a practical overview of drug development, the problems inherent in current practices, and the advantages of adaptive research technology and methods. He explains the concepts, principles, and specific techniques of adaptive research, and demonstrates why it is an essential evolutionary step toward improving drug research and development. Chapters explore such subjects as: The adaptive concept Design and operational adaptations Sample-size reestimation Agile clinical development Safety and dose finding Statistics in adaptive research, including frequentist and Bayesian approaches Data management technologies The future of clinical development By combining centuries-old intellectual foundations, recent technological advances, and modern management techniques, adaptive research preserves the integrity and validity of clinical research but dramatically improves efficiency.
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Elaine Biech Training and Development For Dummies Elaine Biech Training and Development For Dummies Новинка

Elaine Biech Training and Development For Dummies

Develop and deliver a robust employee training and development program Training and Development For Dummies gives you the tools you need to develop a strong and effective training and development program. Covering the latest in talent development, this informative guide addresses classroom, virtual, and blended learning to open up your options and help you design the program that's right for your company. You'll explore the different modes of formal learning, including social learning, m-learning, and MOOCs, and delve into the benefits and implementation of self-directed and informal learning. The discussion covers mentoring and coaching, rotational and stretch assignments, and how to align talent development with the company's needs. You'll learn how to assess employee skills, design and deliver training, and evaluate each step of the process to achieve the goals of both the employee and the organization. Most employees have some weaknesses in their skill sets. A robust training program allows you to strengthen those skills, and a development program brings all employees up to the highest possible level of productivity and success. This book helps you create consistency in your company by developing and delivering the exact training and development program your people need. Develop a strong training and development program Foster a supportive and innovative work environment Learn about social learning, m-learning, and MOOCs Assess and evaluate your staff more effectively A great training and development program boosts performance, productivity, job satisfaction, and quality of services, while reducing costs and supervision. Investing in your employees gives an excellent ROI, as talent development is a primary driver behind both motivation and loyalty. Training and Development For Dummies shows you how to reap these benefits, with step by step guidance and essential expert insight.
Agricultural Subsidies in the WTO Green Box: Ensuring Coherence with Sustainable Development Goals Agricultural Subsidies in the WTO Green Box: Ensuring Coherence with Sustainable Development Goals Новинка

Agricultural Subsidies in the WTO Green Box: Ensuring Coherence with Sustainable Development Goals

Growing evidence suggests that 'green box' farm subsidies may in fact affect production and trade, harm farmers in developing countries and cause environmental damage. This book brings together new research and analysis examining the relationship between green box subsidies and sustainable development goals, and explores options for future reform.
Fred Sherratt Unpacking Construction Site Safety Fred Sherratt Unpacking Construction Site Safety Новинка

Fred Sherratt Unpacking Construction Site Safety

Unpacking Construction Site Safety provides a different perspective of safety in practice. ? examines how useful the concept of safety actually is to the development of effective management interventions ? providing new insights and information to the audience, and assist in a more informed development of new approaches in practice ? aimed at safety and construction management practitioners as well as academics
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Serpell Child Development in Africa: Views From Inside. New Directions for Child and Adolescent Development, Number 146 Serpell Child Development in Africa: Views From Inside. New Directions for Child and Adolescent Development, Number 146 Новинка

Serpell Child Development in Africa: Views From Inside. New Directions for Child and Adolescent Development, Number 146

In this volume, African scholars engaged in research on the continent reflect on their recent and ongoing empirical studies. They discuss the strengths and limitations of research methods, theories, and interventions designed outside Africa to spur innovative research on the continent. And they explore how insights from African philosophical, theoretical, and empirical work can be combined with exogenous forms of knowledge to generate understanding of the processes of African children’s development in ways that are responsive to local contexts and meaningful for indigenous stakeholders. A new field of African child development research is emerging in African societies, focusing on children as valued and vulnerable members of society and potential civic leaders of the future. Systematic inquiries are now designed to enhance our understanding of how African children think, to discover effective ways of communicating with them, and to inform successful strategies of promoting their health, education, and preparation for adult responsibilities in society. This is the 146th volume in this Jossey-Bass series New Directions for Child and Adolescent Development. Its mission is to provide scientific and scholarly presentations on cutting edge issues and concepts in this subject area. Each volume focuses on a specific new direction or research topic and is edited by experts from that field.
Ekins Sean Pharmaceutical Data Mining. Approaches and Applications for Drug Discovery Ekins Sean Pharmaceutical Data Mining. Approaches and Applications for Drug Discovery Новинка

Ekins Sean Pharmaceutical Data Mining. Approaches and Applications for Drug Discovery

Leading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, who address both the implementation of new data mining technologies and application issues in the industry. This accessible, comprehensive collection discusses important theoretical and practical aspects of pharmaceutical data mining, focusing on diverse approaches for drug discovery—including chemogenomics, toxicogenomics, and individual drug response prediction. The five main sections of this volume cover: A general overview of the discipline, from its foundations to contemporary industrial applications Chemoinformatics-based applications Bioinformatics-based applications Data mining methods in clinical development Data mining algorithms, technologies, and software tools, with emphasis on advanced algorithms and software that are currently used in the industry or represent promising approaches In one concentrated reference, Pharmaceutical Data Mining reveals the role and possibilities of these sophisticated techniques in contemporary drug discovery and development. It is ideal for graduate-level courses covering pharmaceutical science, computational chemistry, and bioinformatics. In addition, it provides insight to pharmaceutical scientists, principal investigators, principal scientists, research directors, and all scientists working in the field of drug discovery and development and associated industries.
Вафельница для толстых вафель Gastrorag ZU-HF-1E Вафельница для толстых вафель Gastrorag ZU-HF-1E Новинка

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Lynne Walsh Depression Care Across the Lifespan Lynne Walsh Depression Care Across the Lifespan Новинка

Lynne Walsh Depression Care Across the Lifespan

Depression Care across the Lifespan is a comprehensive, practical text that aims to increase knowledge and understanding of depression enabling professionals to enhance the care delivered to patients with depression. This text explores depression across all ages, starting with children and teenagers, through adulthood and finally old age. Depression Care across the Lifespan explores depression amongst different groups including children and teenagers, depression throughout the adult female lifecycle and depression in later life. It also discusses the impact of depression in people with learning disabilities and those from ethnic minority and immigrant populations. It also looks at topics including the causes and treatment of depression, the impact of stress and depression upon work and wellbeing, depression in chronic illness, suicide and self harm, and managing depression in primary and secondary care are included. Key features: • Essential reading for practitioners involved in the care of depressed people • Useful for students undertaking nursing, health and social care courses • Evidence-based, and supported by relevant literature • Links policy with current practice across the whole lifespan
Managing Motherhood, Managing Risk : Fertility and Danger in West Central Tanzania Managing Motherhood, Managing Risk : Fertility and Danger in West Central Tanzania Новинка

Managing Motherhood, Managing Risk : Fertility and Danger in West Central Tanzania

Book DescriptionAn investigation of the consequences resulting from fertility-related development interventions in Tanzania

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This Task Force report reviews the evidence that the seeds of many adult diseases are sown in utero and in infancy. The report, written by experts in the field, summarises current knowledge in this area. It illustrates how early life nutrition can bring about changes in organ development and function, thus programming risk of disease in adult life. It also considers what might be done in early life to reduce the burden of future ill health. Nutrition and Development: Short- and Long-Term Consequences for Health includes chapters on the history of this topic area, normal growth and development, and current recommendations and practice in relation to nutrition and diet in early life. Chapters exploring the possible mechanisms and pathways of critical windows for development cover the effects of diet and nutrition in early life on organ and skeletal development, the role of sex hormones in programming disease susceptibility, the establishment of gastrointestinal microbiota, and the impact of early life nutrition on cognitive and neurological development. This new report: • describes how development occurs and explores how changes in the fetal and postnatal environment, such as over- or under-nutrition, can result in permanent alterations in function; • explains how diet and nutrition in early life can affect risk of adult disease, with specific chapters on allergic disease and asthma, bone health, cancer, cardiovascular disease, cognitive function, diabetes and obesity; • includes a summary of the key points, as well as recommendations in each chapter to help fill the gaps in our knowledge; • provides an overview of the main messages in a practical question and answer format suitable for lay readers. Nutrition and Development is an important information resource for those involved in research and teaching in the health sciences sector and is also of value to those involved in making decisions about health policy. It will be of interest to a broad range of health professionals, the food industry and those who write and broadcast about the effects of food on health.
Продажа lifespan development in action 1e лучших цены всего мира
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