new carbazole indole and diphenylamine based emissive compounds



Capriati Vito Lithium Compounds in Organic Synthesis. From Fundamentals to Applications Capriati Vito Lithium Compounds in Organic Synthesis. From Fundamentals to Applications Новинка

Capriati Vito Lithium Compounds in Organic Synthesis. From Fundamentals to Applications

17230.59 руб. или Купить в рассрочку!
This unique book covers fundamentals of organolithium compounds and gives a comprehensive overview of the latest synthetic advances and developments in the field. Part I covers computational and spectroscopic aspects as well as structure-reactivity relationships of organolithiums, whereas Part II deals with new lithium-based synthetic methodologies as well as novel synthetic applications of functionalized lithium compounds. A useful resource for newcomers and active researchers involved in organic synthesis, whether working in academia or industry!
Gordon Gribble W. Indole Ring Synthesis. From Natural Products to Drug Discovery Gordon Gribble W. Indole Ring Synthesis. From Natural Products to Drug Discovery Новинка

Gordon Gribble W. Indole Ring Synthesis. From Natural Products to Drug Discovery

16721.84 руб. или Купить в рассрочку!
Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade – highlighted by the power of transition metal catalysis – this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.
Rachel Cerdan Comprehensive Analysis of Parasite Biology. From Metabolism to Drug Discovery Rachel Cerdan Comprehensive Analysis of Parasite Biology. From Metabolism to Drug Discovery Новинка

Rachel Cerdan Comprehensive Analysis of Parasite Biology. From Metabolism to Drug Discovery

17481.17 руб. или Купить в рассрочку!
Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art «omics» technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.
Tim Storr Ligand Design in Medicinal Inorganic Chemistry Tim Storr Ligand Design in Medicinal Inorganic Chemistry Новинка

Tim Storr Ligand Design in Medicinal Inorganic Chemistry

14821.72 руб. или Купить в рассрочку!
Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.
Erick Vandamme J. Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants Erick Vandamme J. Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants Новинка

Erick Vandamme J. Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants

18621.97 руб. или Купить в рассрочку!
Vitamins are a group of physiologically very important, chemically quite complex organic compounds, that are essential for humans and animals. Some vitamins and other growth factors behave as antioxidants, while some can be considered as biopigments. As their chemical synthesis is laborious, their biotechnology-based synthesis and production via microbial fermentation has gained substantial interest within the last decades. Recent progress in microbial genetics and in metabolic engineering and implementation of innovative bioprocess technology has led to a biotechnology-based industrial production of many vitamins and related compounds. Divided into three sections, this volume covers: 1. water-soluble vitamins 2. fat-soluble vitamin compounds and 3. other growth factors, biopigments, and antioxidants. They are all reviewed systematically: from natural occurrence and assays, via biosynthesis, strain development, to industrially-employed biotechnological syntheses and applications.
Thomas Wirth Organoselenium Chemistry. Synthesis and Reactions Thomas Wirth Organoselenium Chemistry. Synthesis and Reactions Новинка

Thomas Wirth Organoselenium Chemistry. Synthesis and Reactions

2169.35 руб. или Купить в рассрочку!
Selenium-based methods in synthetic chemistry have developed rapidly over the past years and are now offering highly useful tools for organic synthesis. Filling the gap for a comprehensive handbook and ready reference, this book covers all modern developments within the field, including biochemical aspects. The chemistry chapters are organized according to the different reactivities of various selenium compounds and reagents, with each chapter dealing with a special reaction type. Also includes a table with 77Se NMR shifts to aid in practical problems. From the Contents: * Electrophilic and Nucleophilic Selenium * Selenium Compounds in Radical Reactions * Selenium-Stabilized Carbanions * Selenium Compounds with Valency Higher than Two * Selenocarbonyls * Selenoxide Elimination and [2,3]-Sigmatropic Rearrangement * Selenium Compounds as Ligands and Catalysts * Biological and Biochemical Aspects of Selenium Compounds
John Tebby C. Alkynes in Cycloadditions John Tebby C. Alkynes in Cycloadditions Новинка

John Tebby C. Alkynes in Cycloadditions

14897.43 руб. или Купить в рассрочку!
Acetylene systems present a new route to cyclic compounds as an alternative to more traditional methods employed in classical organic chemistry. The synthesis of cyclic structures based on acetylene systems has important applications in the formation of nanostructures, naturally occurring compounds and chemosensory materials for the design of nonlinear optics, electronic and photonic devices. Alkynes in Cycloadditions presents a modern review of regioselective synthesis of aromatic and non-aromatic carbocyclic and heterocyclic ring systems based primarily on [2+2+2] and [4+2] cycloadditions, and other reactions of acetylenic units including enediynes and enyne-allenes. Topics covered include: New strategies for the formation of aromatic and polynuclear hydrocarbons based on (Z)-hex-3-en-1,5-diyne and (Z)-hepta-1,2,4-triene-6-yne blocks. One-step synthesis of benzene derivatives, β-substituted naphthalenes and acenes by the cycloaromatization of enediynes and enyne-allenes by Bergman, Myers-Saito and Shmittel. Mechanisms of cycloaromatization resulting in the formation of fulvene and indene systems. Heterocyclization involving enyne-carbodiimides. New achievements in classical cycloaddition reactions such as the Diels-Alder condensation with acetylenic dienophiles and [2+2] cycloadditions with acetylene components Alkynes in Cycloadditions presents a comprehensive summary of the literature on methods for the synthesis of ring systems from acetylenes for academic researchers working in the fields of organic synthesis, physical organic chemistry, organometallic chemistry, catalysis, materials science, nanomaterials and biochemistry.
Ken Tanaka Transition-Metal-Mediated Aromatic Ring Construction Ken Tanaka Transition-Metal-Mediated Aromatic Ring Construction Новинка

Ken Tanaka Transition-Metal-Mediated Aromatic Ring Construction

14514.06 руб. или Купить в рассрочку!
State-of-the-science methods, synthetic routes, and strategies to construct aromatic rings The development of new reactions for the synthesis of aromatic compounds is a highly active research area in organic synthesis, providing new functional organic materials, functional reagents, and biologically active compounds. Recently, significant advances in transition-metal-mediated reactions have enabled the efficient and practical construction of new aromatic rings with useful properties and applications. This book draws together and reviews all the latest discoveries and methods in transition-metal-mediated reactions, offering readers promising new routes to design and construct complex aromatic compounds. Integrating metal catalysis with aromatic compound synthesis, Transition-Metal-Mediated Aromatic Ring Construction offers a practical guide to the methods, synthetic routes, and strategies for constructing aromatic compounds. The book's five parts examine: [2+2+2], [2+2+1], and related cycloaddition reactions [4+2], [3+2], and related cycloaddition reactions Electrocyclization reactions Coupling and addition reactions Other important transformations, including methathesis reactions and skeletal rearrangement reactions Edited by Ken Tanaka, an internationally recognized expert in the field of transition-metal catalysis, the book features authors who are leading pioneers and researchers in synthetic reactions. Their contributions reflect a thorough review and analysis of the literature as well as their own firsthand laboratory experience developing new aromatic compounds. All chapters end with a summary and outlook, setting forth new avenues of research and forecasting new discoveries. There are also references at the end of each chapter, guiding readers to important original research reports and reviews. In summary, Transition-Metal-Mediated Aromatic Ring Construction offers synthetic chemists a promising new avenue for the development of important new aromatic compounds with a broad range of applications.
Van Nguyen Tang Recovering Bioactive Compounds from Agricultural Wastes Van Nguyen Tang Recovering Bioactive Compounds from Agricultural Wastes Новинка

Van Nguyen Tang Recovering Bioactive Compounds from Agricultural Wastes

11400.76 руб. или Купить в рассрочку!
A guide to the extraction, isolation and purification of bioactive compounds from agricultural wastes, and their applications Recovering Bioactive Compounds from Agricultural Wastes offers a guide to the many uses of agricultural wastes from the production of major food types including tea, coffee, cacao, cashew, fruit and vegetables, wine, edible oils, sugar, starch and more. Written by a noted expert in the field, the text explores the various methods for extraction, isolation and purification of bioactive compounds from agricultural wastes. The author also makes recommendations concerning the most effective applications of bioactive compounds and discusses the economics and market for recovered bioactive compounds. Recent studies reveal that bioactive compounds have been directly linked to biological activity such as antioxidant, anticancer, antidiabetic, anti-cardiovascular capacities, etc. In particular, agricultural wastes are considered as potential and inexpensive sources of bioactive compounds. Recovering Bioactive Compounds from Agricultural Wastes fills a gap in the literature by providing a text that explores this important topic and examines the: Sustainability of waste management and shows how to extract, isolate and purify bioactive compounds from agricultural wastes, and their most effective application Wide range of agricultural food produce that can be processed and the special techniques used for recovering the bioactive compounds from these sources Health applications of bioactive compounds that have been directly linked to pharmacological activities including antioxidant, anticancer, and more Designed for use by researchers and producers in the agriculture, pharmaceuticals and nutraceuticals, Recovering Bioactive Compounds from Agricultural Wastes contains the knowledge, history and definition, classification and synthesis, and extraction techniques of bioactive compounds.
Anthonia O'Donovan Biotechnology of Bioactive Compounds. Sources and Applications Anthonia O'Donovan Biotechnology of Bioactive Compounds. Sources and Applications Новинка

Anthonia O'Donovan Biotechnology of Bioactive Compounds. Sources and Applications

21965.76 руб. или Купить в рассрочку!
Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.
David Rowe Chemistry and Technology of Flavours and Fragrances David Rowe Chemistry and Technology of Flavours and Fragrances Новинка

David Rowe Chemistry and Technology of Flavours and Fragrances

22353.2 руб. или Купить в рассрочку!
Modern flavours and fragrances are complex formulated products, containing blends of aroma compounds with auxiliary materials, enabling desirable flavours or fragrances to be added to a huge range of products. From the identification and synthesis of materials such as cinnamaldehyde and vanillin in the 19th Century to the current application of advanced analytical techniques for identification of trace aroma compounds present in natural materials, the flavour and fragrance industry has developed as a key part of the worldwide specialty chemicals industry. With contributions mainly coming from industry based experts, Chemistry & Technology of Flavours and Fragrances provides a detailed overview of the synthesis, chemistry and application technology of the major classes aroma compounds. With separate chapters covering important technical aspects such as the stability of aroma compounds, structure – odour relationships and identification of aroma compounds, this book will be essential reading for both experienced and graduate level entrants to the flavour & fragrance industry. It will also serve as an important introduction to the subject for chemists and technologists in those industries that use flavours and fragrances, eg food, cosmetics & toiletries, and household products. David Rowe is Technical Manager at De Monchy Aromatics Ltd., Poole UK
Lee Vladimir Ya. Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb. From Phantom Species to Stable Compounds Lee Vladimir Ya. Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb. From Phantom Species to Stable Compounds Новинка

Lee Vladimir Ya. Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb. From Phantom Species to Stable Compounds

16997.75 руб. или Купить в рассрочку!
Until recently the low-coordinate compounds of the heavier elements of group 14 were known only as transient, unstable species which were difficult to isolate. However recent developments have led to the stabilisation of these compounds and today heavier group 14 element cations, radicals, anions, carbene analogues, alkene and alkyne analogues and aromatics have all been prepared as highly reactive, stable, fully characterizable and readily available organometallic reagents. Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb describes the chemistry of this exciting new class of organometallics, with an emphasis on their major similarities and differences with the analogous species in organic chemistry. Topics covered include include the synthesis, structure, reactions and synthetic applications of : Si-, Ge-, Sn and Pb-centered cations, radicals and anions heavy analogues of carbenes: silylenes, germylenes, stannylenes and plumbylenes heavy analogues of alkenes: disilenes, digermenes, distannenes, diplumbenes heavy analogues of alkynes: disilynes, digermynes, distannynes, diplumbynes, and their valence isomers heteronuclear derivatives: silenes, germenes, stannenes, silagermenes, silastannenes, germastannenes heavy analogues of alkenes of the type: >E14=E13-, >E14=E15-, >E14=E16 [where E13, E14, E15 and E16 are elements of the groups 13, 14, 15 and 16] cyclic compounds (three-, four-, five-, and six-membered rings) heavy analogues of 1,3-dienes, allenes and other cumulenes heavy analogues of aromatic compounds; including a comparison between organometallic and organic aromaticity Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb is an essential guide to this emerging class of organometallic reagents for researchers and students in main group, organometallic, synthetic and silicon chemistry
Matheus Poletto Polypropylene-Based Biocomposites and Bionanocomposites Matheus Poletto Polypropylene-Based Biocomposites and Bionanocomposites Новинка

Matheus Poletto Polypropylene-Based Biocomposites and Bionanocomposites

12612.48 руб. или Купить в рассрочку!
This book discusses new developments in an up-to-date, coherent and objective set of chapters by eminent researchers in the area of polypropylene-based biocomposites and bionanocomposites. It covers, biomaterials such as cellulose, chitin, starch, soy protein, hemicelluloses, polylactic acid and polyhydroxyalkanoates. Other important topics such as hybrid biocomposites and bionanocomposites of polypropylene, biodegradation study of polypropylene-based biocomposites and bionanocomposites, polypropylene-based bionanocomposites for packaging applications, polypropylene-based carbon nanomaterials reinforced nanocomposites, degradation and flame retardency of polypropylene-based composites and nanocomposites, are covered as well.
Kamran T. Mahmudov Non-covalent Interactions in the Synthesis and Design of New Compounds Kamran T. Mahmudov Non-covalent Interactions in the Synthesis and Design of New Compounds Новинка

Kamran T. Mahmudov Non-covalent Interactions in the Synthesis and Design of New Compounds

14821.72 руб. или Купить в рассрочку!
This book aims to overview the role of non-covalent interactions, such as hydrogen and halogen bonding, π-π, π-anion and electrostatic interactions, hydrophobic effects and van der Waals forces in the synthesis of organic and inorganic compounds, as well as in design of new crystals and function materials. The proposed book should allow to combine, in a systematic way, recent advances on the application of non-covalent interactions in synthesis and design of new compounds and functional materials with significance in Inorganic, Organic, Coordination, Organometallic, Pharmaceutical, Biological and Material Chemistries. Therefore, it should present a multi- and interdisciplinary character assuring a rather broad scope. We believe it will be of interest to a wide range of academic and research staff concerning the synthesis of new compounds, catalysis and materials. Each chapter will be written by authors who are well known experts in their respective fields.
Johannes Fink Karl The Chemistry of Bio-based Polymers Johannes Fink Karl The Chemistry of Bio-based Polymers Новинка

Johannes Fink Karl The Chemistry of Bio-based Polymers

15728.87 руб. или Купить в рассрочку!
An exhaustive and timely overview of renewable polymers from a respected chemist and successful author The recent explosion of interdisciplinary research has fragmented the knowledge base surrounding renewable polymers. The Chemistry of Bio-based Polymers brings together, in one volume, the research and work of Professor Johannes Fink, focusing on biopolymers that can be synthesized from renewable polymers. After introducing general aspects of the field, the book’s subsequent chapters examine the chemistry of biodegradable polymeric types sorted by their chemical compounds, including the synthesis of low molecular compounds. Various categories of biopolymers are detailed including vinyl-based polymers, acid and lactone polymers, ester and amide polymers, carbohydrate-related polymers and others. Procedures for the preparation of biopolymers and biodegradable nanocomposites are arranged by chemical methods and in vitro biological methods, with discussion of the issue of “plastics from bacteria.” The factors influencing the degradation and biodegradation of polymers used in food packaging, exposed to various environments, are detailed at length. The book covers the medical applications of bio-based polymers, concentrating on controlled drug delivery, temporary prostheses, and scaffolds for tissue engineering. Professor Fink also addresses renewable resources for fabricating biofuels and argues for localized biorefineries, as biomass feedstocks are more efficiently handled locally. Audience The Chemistry of Bio-based Polymers will be read by chemists, polymer and materials scientists, chemical, bio-based, and biomedical engineers, agricultural and environmental faculty and all those who work in the bioeconomy area. This book will be critical for engineers in a number of industries including food packaging, medical devices, personal care, fuels, auto, and construction.
Alfred Sattelberger P. Inorganic Syntheses Alfred Sattelberger P. Inorganic Syntheses Новинка

Alfred Sattelberger P. Inorganic Syntheses

11017.13 руб. или Купить в рассрочку!
This volume of Inorganic Syntheses spans the preparations of wide range of important inorganic, organometallic and solid-state compounds. The volume is divided into 6 chapters. The first chapter contains the syntheses of some key early transition metal halide clusters and the very useful mononuclear molybdenum(III) synthon, MoCl3(THF)3. Chapter 2 covers the synthesis of a number of cyclopentadienyl compounds, including a novel route to sodium and potassium cyclopentadienide, MC5H5. Chapter 3 details synthetic procedures for a range of metal-metal bonded compounds, including several with metal-metal multiple bonds. Chapter 4 contains procedures for a range of early and late transition metal compounds, each a useful synthon for further synthetic elaboration. Chapter 5 deals with the synthesis of a number of main group compounds and ligands, while Chapter 6 covers teaching laboratory experiments.
I. I. Tolpeshta Aluminum compounds in soils. Manual I. I. Tolpeshta Aluminum compounds in soils. Manual Новинка

I. I. Tolpeshta Aluminum compounds in soils. Manual

The manual presents general information on the chemistry, pedochemistry, and geochemistry of aluminum, considers the main groups of aluminum compounds in the soil solid phase and the soil solution, as well as processes with the participation of mobile aluminum in the soils of humid extratropical regions. Special attention is given to the toxic properties of aluminum compounds, as well as toxic effects and parameters for the estimation of the toxicity of aluminum compounds. Methods for the determination of toxic aluminum compounds in soil solutions and surface waters. The manual can be used for the courses of lectures in Soil Science, Soil Chemistry, and Ecology.
Daniel Lednicer Antineoplastic Drugs. Organic Syntheses Daniel Lednicer Antineoplastic Drugs. Organic Syntheses Новинка

Daniel Lednicer Antineoplastic Drugs. Organic Syntheses

10261.41 руб. или Купить в рассрочку!
The past decade has seen a significant increase of research aimed at discovering new drugs for treating cancer, and the increasing number of new antineoplastic drugs approved by regulatory agencies reflects this. Until now, details on the synthesis of these newer agents have been scattered in various journals and in US and European patents. This timely volume deals with the organic chemistry involved in the synthesis of the agents found within antineoplastic drugs, including descriptions of the synthetic schemes for the preparation of over 200 compounds that have been granted non-proprietary names. Compounds are collected in chapters based on the mechanism of action rather than on their chemical structures. Each individual chapter is preceded by a brief description of that mechanism and includes detailed flow charts of the preparation of those compounds accompanied by discussions of the organic chemistry involved in each step. The first half of this volume is dedicated to the syntheses of established chemotherapy drugs. Kinase inhibitors occupy the following chapters with the largest single chapter dealing with the fifty compounds that inhibit tyrosine kinase. This class stands out since over twenty compounds in this group have been approved for treating patients; a rare track record compared to any other class of therapeutic agents. Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations. The book is accessible to advanced undergraduates as well as graduates and researchers as well as those with a thorough grasp of organic chemistry.
Jacques Mortier Arene Chemistry. Reaction Mechanisms and Methods for Aromatic Compounds Jacques Mortier Arene Chemistry. Reaction Mechanisms and Methods for Aromatic Compounds Новинка

Jacques Mortier Arene Chemistry. Reaction Mechanisms and Methods for Aromatic Compounds

14821.72 руб. или Купить в рассрочку!
Organized to enable students and synthetic chemists to understand and expand on aromatic reactions covered in foundation courses, the book offers a thorough and accessible mechanistic explanation of aromatic reactions involving arene compounds. • Surveys methods used for preparing arene compounds and their transformations • Connects reactivity and methodology with mechanism • Helps readers apply aromatic reactions in a practical context by designing syntheses • Provides essential information about techniques used to determine reaction mechanisms
Jie Jack Li Heterocyclic Chemistry in Drug Discovery Jie Jack Li Heterocyclic Chemistry in Drug Discovery Новинка

Jie Jack Li Heterocyclic Chemistry in Drug Discovery

12161.54 руб. или Купить в рассрочку!
Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go hand in hand in the effective practice of medicinal chemistry. Contributions from international leaders in the field review more than 100 years of findings, explaining their relevance to contemporary drug discovery practice. Moreover, these authors have provided plenty of practical guidance and tips based on their own academic and industrial laboratory experience, helping readers avoid common pitfalls. Heterocyclic Chemistry in Drug Discovery is ideal for readers who want to fully realize the almost limitless potential to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features: Several case studies illustrating the role and application of 3, 4, 5, and 6+ heterocyclic ring systems in drug discovery Step-by-step descriptions of synthetic methods and practical techniques Examination of the physical properties for each heterocycle, including NMR data and quantum calculations Detailed explanations of the complexity and intricacies of reactivity and stability for each class of heterocycles Heterocyclic Chemistry in Drug Discovery is recommended as a textbook for organic and medicinal chemistry courses, particularly those emphasizing heterocyclic chemistry. The text also serves as a guide for medicinal and process chemists in the pharmaceutical industry, offering them new insights and new paths to explore for effective drug discovery.
Ashutosh Tiwari Advanced Molecularly Imprinting Materials Ashutosh Tiwari Advanced Molecularly Imprinting Materials Новинка

Ashutosh Tiwari Advanced Molecularly Imprinting Materials

17101.87 руб. или Купить в рассрочку!
Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications. In this book, the chapters are clustered into two main sections: Strategies to be employed when using the affinity materials, and rational design of MIPs for advanced applications. In the first part, the book covers the recent advances in producing MIPs for sample design, preparation and characterizations. In the second part, the chapters demonstrate the importance and novelty of creation of recognition imprinted on the materials and surfaces for a range of microbial detection sensors in the biomedical, environmental and food safety fields as well as sensing human odor and virus monitoring systems. Part 1: Strategies of affinity materials Molecularly imprinted polymers MIP nanomaterials Micro- and nanotraps for solid phase extraction Carbonaceous affinity nanomaterials Fluorescent MIPs MIP-based fiber optic sensors Part 2: Rational design of MIP for advanced applications MIP-based biomedical and environmental sensors Affinity adsorbents for environmental biotechnology MIP in food safety MIP-based virus monitoring MIP-based drug delivery and controlled release Biorecognition imprints on the biosensor surfaces MIP-based sensing of volatile organic compounds in human body odour MIP-based microcantilever sensor system
Senaratne Sepani Managing Change in Construction Projects. A Knowledge-Based Approach Senaratne Sepani Managing Change in Construction Projects. A Knowledge-Based Approach Новинка

Senaratne Sepani Managing Change in Construction Projects. A Knowledge-Based Approach

10788.52 руб. или Купить в рассрочку!
Managing Change in Construction Projects: a knowledge-based approach offers a new perspective on construction project change by viewing the process of change management as a knowledge-intensive activity, where team members bring their tacit and explicit knowledge into the situation; share, create and capture this collective knowledge for future re-use in similar situations. Through this knowledge-based approach, construction teams can successfully resolve and learn from change events, leading to an overall improved performance of the industry. The book will make a significant contribution to our understanding of construction project change by offering new theoretical and practical insights and models grounded in results of case studies conducted within two collaborative construction project team settings. By demonstrating how the social construction of knowledge works in construction settings, the authors challenge the prevailing change management solutions based on ‘hard’ IT approaches. They put forward a balanced view that incorporates both IT–based and socially constructed approaches to effective management of construction project change. helps construction managers to improve and learn through the process of construction project change presents new theoretical models and offers practical guidelines first research-based book to directly address project change from a knowledge-based perspective draws on detailed studies with construction companies, including Ballast Construction and Kier Construction encourages a move from the information driven, process integrated approach to a knowledge-based view
Edward Jr. Maslowsky Vibrational Spectra of Organometallics. Theoretical and Experimental Data Edward Jr. Maslowsky Vibrational Spectra of Organometallics. Theoretical and Experimental Data Новинка

Edward Jr. Maslowsky Vibrational Spectra of Organometallics. Theoretical and Experimental Data

14229.47 руб. или Купить в рассрочку!
A comprehensive compilation of the available experimental and theoretical vibrational data for organometallic compounds and its role in evaluating the structures, bonding, and properties of these key compounds This unique book offers a thorough review of the literature dealing with vibrational data obtained using various phases, including matrices, reported for organometallic compounds from infrared spectra, Raman spectra, and several other techniques. It is the only one that compiles the available experimental and theoretical vibrational data on these compounds, and which discusses the importance of this information and its role in evaluating structures, bonding, and other important properties. It also treats the use of DFT and other theoretical calculations to analyze the vibrational data and to predict properties associated with these compounds. The book also includes vibrational data for organic species that form on metal and other surfaces. Vibrational Spectra of Organometallics: Theoretical and Experimental Data offers complete coverage of: Carbide, Alkylidyne, Alkylidene, Alkyl, and Alkane Derivatives; Noncyclic Carbon‐Clusters and Unsaturated Hydrocarbon Derivatives; and Cyclic, Unsaturated Organometallic Derivatives. By summarizing work that has already been done on organometallic compounds, it serves as an important reference for those studying their vibrational spectra and will, in the end, lead to a clearer understanding of other research that needs to be done in order to help researchers determine new research directions. An important reference for those studying the vibrational spectra of organometallic compounds Gathers the existing experimental and theoretical vibrational data and discusses its significance in assessing structures, bonding, and other principle properties Includes DFT methods for the interpretation of spectra, which has been one of the major developments of the last two decades Vibrational Spectra of Organometallics: Theoretical and Experimental Data is an important reference for researchers and practitioners in the areas of inorganic, organometallic, organic, and surface chemistry who have an interest in using vibrational data to characterize the bonding, composition, reactions, and structures of organometallic compounds, and organic species that are formed on various surfaces.
Trisha Greenhalgh How to Read a Paper. The Basics of Evidence-Based Medicine Trisha Greenhalgh How to Read a Paper. The Basics of Evidence-Based Medicine Новинка

Trisha Greenhalgh How to Read a Paper. The Basics of Evidence-Based Medicine

4032.11 руб. или Купить в рассрочку!
The best-selling introduction to evidence-based medicine In a clear and engaging style, How to Read a Paper demystifies evidence-based medicine and explains how to critically appraise published research and also put the findings into practice. An ideal introduction to evidence-based medicine, How to Read a Paper explains what to look for in different types of papers and how best to evaluate the literature and then implement the findings in an evidence-based, patient-centred way. Helpful checklist summaries of the key points in each chapter provide a useful framework for applying the principles of evidence-based medicine in everyday practice. This fifth edition has been fully updated with new examples and references to reflect recent developments and current practice. It also includes two new chapters on applying evidence-based medicine with patients and on the common criticisms of evidence-based medicine and responses. How to Read a Paper is a standard text for medical and nursing schools as well as a friendly guide for everyone wanting to teach or learn the basics of evidence-based medicine.
Christian Rojas M. Molecular Rearrangements in Organic Synthesis Christian Rojas M. Molecular Rearrangements in Organic Synthesis Новинка

Christian Rojas M. Molecular Rearrangements in Organic Synthesis

14821.72 руб. или Купить в рассрочку!
Designed for practitioners of organic synthesis, this book helps chemists understand and take advantage of rearrangement reactions to enhance the synthesis of useful chemical compounds. Provides ready access to the genesis, mechanisms, and synthetic utility of rearrangement reactions Emphasizes strategic synthetic planning and implementation Covers 20 different rearrangement reactions Includes applications for synthesizing compounds useful as natural products, medicinal compounds, functional materials, and physical organic chemistry
Christian Stevens Bio-Based Plastics. Materials and Applications Christian Stevens Bio-Based Plastics. Materials and Applications Новинка

Christian Stevens Bio-Based Plastics. Materials and Applications

14593.12 руб. или Купить в рассрочку!
The field of bio-based plastics has developed significantly in the last 10 years and there is increasing pressure on industries to shift existing materials production from petrochemicals to renewables. Bio-based Plastics presents an up-to-date overview of the basic and applied aspects of bioplastics, focusing primarily on thermoplastic polymers for material use. Emphasizing materials currently in use or with significant potential for future applications, this book looks at the most important biopolymer classes such as polysaccharides, lignin, proteins and polyhydroxyalkanoates as raw materials for bio-based plastics, as well as materials derived from bio-based monomers like lipids, poly(lactic acid), polyesters, polyamides and polyolefines. Detailed consideration is also given to the market and availability of renewable raw materials, the importance of bio-based content and the aspect of biodegradability. Topics covered include: Starch Cellulose and cellulose acetate Materials based on chitin and chitosan Lignin matrix composites from natural resources Polyhydroxyalkanoates Poly(lactic acid) Polyesters, Polyamides and Polyolefins from biomass derived monomers Protein-based plastics Bio-based Plastics is a valuable resource for academic and industrial researchers who are interested in new materials, renewable resources, sustainability and polymerization technology. It will also prove useful for advanced students interested in the development of bio-based products and materials, green and sustainable chemistry, polymer chemistry and materials science. For more information on the Wiley Series in Renewable Resources, visit www.wiley.com/go/rrs
John LaMattina L. Drug Truths. Dispelling the Myths About Pharma R & D John LaMattina L. Drug Truths. Dispelling the Myths About Pharma R & D Новинка

John LaMattina L. Drug Truths. Dispelling the Myths About Pharma R & D

2479.81 руб. или Купить в рассрочку!
This book answers the questions about the process and costs of pharmaceutical R & D in a compelling narrative focused on the discovery and development of important new medicines. It gives an insider's account of the pharmaceutical industry drug discovery process, the very real costs of misperceptions about the industry, the high stakes–both economic and scientific–of developing drugs, the triumphs that come when new compounds reach the market and save lives, and the despair that follows when new compounds fail. In the book, John LaMattina, former president of Pfizer Global Research and Development, weaves themes critical to a vital drug discovery environment in the context. This is a story that Dr. LaMattina is uniquely qualified to tell.
Flamini Riccardo Mass Spectrometry in Grape and Wine Chemistry Flamini Riccardo Mass Spectrometry in Grape and Wine Chemistry Новинка

Flamini Riccardo Mass Spectrometry in Grape and Wine Chemistry

9934.76 руб. или Купить в рассрочку!
A concise, up-to-date overview of the applications of mass spectrometry To be able to estimate the potentiality of grapes and how it may be transferred into wine is key to grasping enological chemistry. Nowadays, mass spectrometry is a crucial aspect in ensuring the production, the quality, and the safety of grape, wine, and grape derivative products. Mass Spectrometry in Grape and Wine Chemistry examines in depth the relationship between the high structural identification power of mass spectrometry techniques and the chemistry of grapes and wine. The text is divided into two parts. The first section provides an overview of mass spectrometry methods in relation to enology in three chapters. The second section offers seven chapters on wine chemistry as well as traditional topics and new developments in mass spectrometry. Mass Spectrometry in Grape and Wine Chemistry explores many mass spectrometry applications, including: Ionization methods Mass analyzers and mass measurements Mass spectrometry methodologies Grape aroma compounds Volatile and aroma compounds in wines Grape and wine polyphenols Compounds released by wood into wine Wine defects caused by compounds Pesticide detection analysis Peptides and proteins of grape and wine Written by leading experts in the field, this book presents an introduction to mass spectrometry and outlines ways to maximize quality control and product safety for the best results. Mass Spectrometry in Grape and Wine Chemistry is an essential handbook for laboratories working in enology.
Felix Carroll A. Solutions Manual for Perspectives on Structure and Mechanism in Organic Chemistry Felix Carroll A. Solutions Manual for Perspectives on Structure and Mechanism in Organic Chemistry Новинка

Felix Carroll A. Solutions Manual for Perspectives on Structure and Mechanism in Organic Chemistry

3721.65 руб. или Купить в рассрочку!
Helps to develop new perspectives and a deeper understanding of organic chemistry Instructors and students alike have praised Perspectives on Structure and Mechanism in Organic Chemistry because it motivates readers to think about organic chemistry in new and exciting ways. Based on the author's first hand classroom experience, the text uses complementary conceptual models to give new perspectives on the structures and reactions of organic compounds. The first five chapters of the text discuss the structure and bonding of stable molecules and reactive intermediates. These are followed by a chapter exploring the methods that organic chemists use to study reaction mechanisms. The remaining chapters examine different types of acid-base, substitution, addition, elimination, pericyclic, and photochemical reactions. This Second Edition has been thoroughly updated and revised to reflect the latest findings in physical organic chemistry. Moreover, this edition features: New references to the latest primary and review literature More study questions to help readers better understand and apply new concepts in organic chemistry Coverage of new topics, including density functional theory, quantum theory of atoms in molecules, Marcus theory, molecular simulations, effect of solvent on organic reactions, asymmetric induction in nucleophilic additions to carbonyl compounds, and dynamic effects on reaction pathways The nearly 400 problems in the text do more than allow students to test their understanding of the concepts presented in each chapter. They also encourage readers to actively review and evaluate the chemical literature and to develop and defend their own ideas. With its emphasis on complementary models and independent problem-solving, this text is ideal for upper-level undergraduate and graduate courses in organic chemistry.
Gary Carter W. J.K. Lasser's Taxes Made Easy for Your Home-Based Business. The Ultimate Tax Handbook for the Self-Employed Gary Carter W. J.K. Lasser's Taxes Made Easy for Your Home-Based Business. The Ultimate Tax Handbook for the Self-Employed Новинка

Gary Carter W. J.K. Lasser's Taxes Made Easy for Your Home-Based Business. The Ultimate Tax Handbook for the Self-Employed

1096.32 руб. или Купить в рассрочку!
* Completely updated for all the new tax laws * Capitalize on every deduction! * Sole proprietor, corporation, or partnership? The Ultimate Guide to Running a Tax-Efficient Home-Based Business The advantages of operating a home-based business are countless, but what many owners don't realize, and are often not prepared to handle, are the host of complex tax issues surrounding a home-based business. The completely updated Fifth Edition of J.K. Lasser's Taxes Made Easy for Your Home-Based Business clarifies the current tax environment with regard to home-based businesses, and shows you how to make the most of the new tax laws. This perennial guide answers home-based business owners' questions, with a special focus on the changing tax laws and deductions for the home office. Expert advice and in-depth insights will help you avoid costly mistakes and take advantage of opportunities you would otherwise miss. Critical coverage will help you: * Navigate the details of the new tax laws and IRS rules * Increase your knowledge of deductible expenses * Keep your records up to IRS standards * Organize and run a home-based business for maximum tax benefits * Make filing easy by utilizing sample tax forms
Ji Zhang Macrocyclic Polyamines. Synthesis and Applications Ji Zhang Macrocyclic Polyamines. Synthesis and Applications Новинка

Ji Zhang Macrocyclic Polyamines. Synthesis and Applications

12541.56 руб. или Купить в рассрочку!
The first comprehensive book focusing on synthesis and applications of macrocyclic polyamines and their derivatives Macrocyclic polyamines are a class of widely used important compounds. This is the first book that systematically summarizes the synthesis and applications of macrocyclic polyamines and their analogues, including the properties and synthetic methods of macrocyclic polyamines, chemical nucleases based on macrocyclic polyamines, the derivatives of macrocyclic polyamines as nano-vector materials, macrocyclic polyamines derivatives for bio-imaging, chemical sensors based on macrocyclic polyamines, and other applications of macrocyclic polyamines. Macrocyclic Polyamines: Synthesis and Applications includes most of the studies involving macrocyclic polyamines and their derivatives, and may be used as a reference for the researchers in related fields. It offers in-depth coverage of cyclization modes; special procedures for tetraza macrocyclic compounds; diacids-diamines condensation; oxidative DNA cleaving by macrocyclic polyamines; lipids with cationic MPA headgroups; the derivatives of DOTA, DO3A, and PCTA; receptors for anions; sensors for bioactive molecules; macrocyclic polyamines for solvent extraction and membrane transport of amino acids and their derivatives, electrophoretic separation, and open-tubular CEC; and much more. The first book that systematically summarizes the chemistry of macrocyclic polyamines and their derivatives in terms of synthetic methods for their preparation, functionalization, and application in the main fields of chemical sensors, chemical nucleases, drug-delivery, bio-imaging and vector materials Provides a comprehensive reference for the researchers working on macrocyclic polyamines Offers train of thought in related research fields such as organic chemistry, coordination chemistry, analytical chemistry, supramolecular chemistry, biomaterials, etc. Macrocyclic Polyamines: Synthesis and Applications will not only provide a reference for the researchers working on macrocyclic polyamines, but also offer opportunities for researchers in related research fields to understand the benefits of these key compounds.
Peter Brinckerhoff C. Mission-Based Marketing. Positioning Your Not-for-Profit in an Increasingly Competitive World Peter Brinckerhoff C. Mission-Based Marketing. Positioning Your Not-for-Profit in an Increasingly Competitive World Новинка

Peter Brinckerhoff C. Mission-Based Marketing. Positioning Your Not-for-Profit in an Increasingly Competitive World

3492.69 руб. или Купить в рассрочку!
A direct, practical guide revealing how you can lead your not-for-profit to success through mission-based marketing Now in a Third Edition, Mission-Based Marketing is a direct, practical guide showing how you can lead your not-for-profit to success in a more competitive world. This book provides the knowledge and skills you need to build a market-driven organization that holds onto its core values, does a better job of providing mission, and successfully competes for funding, clients, referral sources, staff, and board members. Includes new material on nonprofit websites, social networking and new methods of communication, advances in technology, customer service in today's world, and the effects of marketing on fundraising Goes beyond the hows and whys to include lots of hands-on advice and real-world examples Other titles by Brinckerhoff: Mission-Based Management: Leading Your Not-for-Profit In the 21st Century, Faith-Based Management: Leading Organizations That Are Based on More than Just Mission, and Social Entrepreneurship: The Art of Mission-Based Venture Development Filled with new material, this book appraises the trends that have dramatically affected the not-for-profit sector in the past several years, and explains how an organization can shape this shifting landscape to its ultimate benefit.
Felix Carroll A. Perspectives on Structure and Mechanism in Organic Chemistry Felix Carroll A. Perspectives on Structure and Mechanism in Organic Chemistry Новинка

Felix Carroll A. Perspectives on Structure and Mechanism in Organic Chemistry

11254.22 руб. или Купить в рассрочку!
Helps to develop new perspectives and a deeper understanding of organic chemistry Instructors and students alike have praised Perspectives on Structure and Mechanism in Organic Chemistry because it motivates readers to think about organic chemistry in new and exciting ways. Based on the author's first hand classroom experience, the text uses complementary conceptual models to give new perspectives on the structures and reactions of organic compounds. The first five chapters of the text discuss the structure and bonding of stable molecules and reactive intermediates. These are followed by a chapter exploring the methods that organic chemists use to study reaction mechanisms. The remaining chapters examine different types of acid-base, substitution, addition, elimination, pericyclic, and photochemical reactions. This Second Edition has been thoroughly updated and revised to reflect the latest findings in physical organic chemistry. Moreover, this edition features: New references to the latest primary and review literature More study questions to help readers better understand and apply new concepts in organic chemistry Coverage of new topics, including density functional theory, quantum theory of atoms in molecules, Marcus theory, molecular simulations, effect of solvent on organic reactions, asymmetric induction in nucleophilic additions to carbonyl compounds, and dynamic effects on reaction pathways The nearly 400 problems in the text do more than allow students to test their understanding of the concepts presented in each chapter. They also encourage readers to actively review and evaluate the chemical literature and to develop and defend their own ideas. With its emphasis on complementary models and independent problem-solving, this text is ideal for upper-level undergraduate and graduate courses in organic chemistry.
Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology Новинка

Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology

16721.84 руб. или Купить в рассрочку!
Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.
Anders Wallgren Register-based Statistics. Statistical Methods for Administrative Data Anders Wallgren Register-based Statistics. Statistical Methods for Administrative Data Новинка

Anders Wallgren Register-based Statistics. Statistical Methods for Administrative Data

9424.92 руб. или Купить в рассрочку!
This book provides a comprehensive and up to date treatment of theory and practical implementation in Register-based statistics. It begins by defining the area, before explaining how to structure such systems, as well as detailing alternative approaches. It explains how to create statistical registers, how to implement quality assurance, and the use of IT systems for register-based statistics. Further to this, clear details are given about the practicalities of implementing such statistical methods, such as protection of privacy and the coordination and coherence of such an undertaking. This edition offers a full understanding of both the principles and practices of this increasingly popular area of statistics, and can be considered a first step to a more systematic way of working with register-statistical issues. This book addresses the growing global interest in the topic and employs a much broader, more international approach than the 1st edition. New chapters explore different kinds of register-based surveys, such as preconditions for register-based statistics and comparing sample survey and administrative data. Furthermore, the authors present discussions on register-based census, national accounts and the transition towards a register-based system as well as presenting new chapters on quality assessment of administrative sources and production process quality.
Gawley Robert E. Stereochemical Aspects of Organolithium Compounds Gawley Robert E. Stereochemical Aspects of Organolithium Compounds Новинка

Gawley Robert E. Stereochemical Aspects of Organolithium Compounds

14436.44 руб. или Купить в рассрочку!
Topics in Stereochemistry, previously edited by «the father of stereochemistry» Ernest L. Eliel, is a longstanding, successful series covering the most important advances in the field. The much-anticipated Volume 26 on stereochemical aspects of organolithium compounds includes chapters on the following topics: * Asymmetric Deprotonations Using Chiral Lithium Amide Bases * Self-Regeneration of Stereocenters (SRS) via Stereolabile Axially Chiral Intermediates * Overview of Carbanion Dynamics and Electrophilic Substitutions in Chiral Organolithium Compounds * Oxiranyllithiums as Chiral Synthons for Asymmetric Synthesis * Test on the Configurational Stability/Lability of Organolithium Compounds * Mechanism and Stereochemical Features in Asymmetric Deprotonation Using RLi/(-)-Sparteine Bases * Dynamic Resolutions of Chiral Organolithiums Volume 26 of Topics in Stereochemistry marks the end of an era, while developing a bridge to the next generation. A new generation in publishing, parallel to a new generation in Stereochemistry mandated a new venue and modus operandi for Topics. Zurich, the home of Werner and Wislicenus, has a unique heritage in Stereochemistry. Fortunately, the Wiley family's publishing partnerships include Verlag Helvetica Chimica Acta, a house with a reputation for superior quality in publishing. Indeed, within the pages of its namesake periodical, Helvetica Chimica Acta, one finds many of the seminal research works of stereochemistry's giants. As such, a transfer of editorial operations to Zurich and a collaboration bringing Topics as a series closer to periodical status provides a growth platform for the future.
Linford Lloyd Brain-Based Therapy with Adults. Evidence-Based Treatment for Everyday Practice Linford Lloyd Brain-Based Therapy with Adults. Evidence-Based Treatment for Everyday Practice Новинка

Linford Lloyd Brain-Based Therapy with Adults. Evidence-Based Treatment for Everyday Practice

4268.84 руб. или Купить в рассрочку!
Brain-Based Therapy with Adults: Evidence-Based Treatment for Everyday Practice provides a straightforward, integrated approach that looks at what we currently know about the brain and how it impacts and informs treatment interventions. Authors John Arden and Lloyd Linford, experts in neuroscience and evidence-based practice, reveal how this new kind of therapy takes into account the uniqueness of each client. Presentation of detailed background and evidence-based?interventions for common adult disorders such as anxiety and depression offers you expert advice you can put into practice immediately.
George Donald A.R. Nonlinearity, Complexity and Randomness in Economics. Towards Algorithmic Foundations for Economics George Donald A.R. Nonlinearity, Complexity and Randomness in Economics. Towards Algorithmic Foundations for Economics Новинка

George Donald A.R. Nonlinearity, Complexity and Randomness in Economics. Towards Algorithmic Foundations for Economics

2790.27 руб. или Купить в рассрочку!
Nonlinearity, Complexity and Randomness in Economics presents a variety of papers by leading economists, scientists, and philosophers who focus on different aspects of nonlinearity, complexity and randomness, and their implications for economics. A theme of the book is that economics should be based on algorithmic, computable mathematical foundations. Features an interdisciplinary collection of papers by economists, scientists, and philosophers Presents new approaches to macroeconomic modelling, agent-based modelling, financial markets, and emergent complexity Reveals how economics today must be based on algorithmic, computable mathematical foundations
Visakh M. P. Polyethylene-Based Blends, Composites and Nanocomposities Visakh M. P. Polyethylene-Based Blends, Composites and Nanocomposities Новинка

Visakh M. P. Polyethylene-Based Blends, Composites and Nanocomposities

14821.72 руб. или Купить в рассрочку!
The book focusses on the recent technical research accomplishments in the area of polyethylene-based blends, composites and nanocomposites by looking at the various aspects of processing, morphology, properties and applications. In particular, the book details the important developments in areas such as the structure-properties relationship of polyethylene; modification of polyethylene with radiation and ion implantation processes; stabilization of irradiated polyethylene by the introduction of antioxidants; reinforcement of polyethylene through carbon-based materials as additives; characterization of carbon-based polyethylenes composites, polyethylene-based blends with thermoplastic and thermoset; characterization of polyethylene-based thermoplastic and thermoset blends; polyethylene-based blends with natural rubber and synthetic rubber; characterization of polyethylene-based natural rubber and synthetic rubber blends; characterization of polyethylene-based composites.
Ian O'Hara Sugarcane-based Biofuels and Bioproducts Ian O'Hara Sugarcane-based Biofuels and Bioproducts Новинка

Ian O'Hara Sugarcane-based Biofuels and Bioproducts

15198.14 руб. или Купить в рассрочку!
Sugarcane has garnered much interest for its potential as a viable renewable energy crop. While the use of sugar juice for ethanol production has been in practice for years, a new focus on using the fibrous co-product known as bagasse for producing renewable fuels and bio-based chemicals is growing in interest. The success of these efforts, and the development of new varieties of energy canes, could greatly increase the use of sugarcane and sugarcane biomass for fuels while enhancing industry sustainability and competitiveness. Sugarcane-Based Biofuels and Bioproducts examines the development of a suite of established and developing biofuels and other renewable products derived from sugarcane and sugarcane-based co-products, such as bagasse. Chapters provide broad-ranging coverage of sugarcane biology, biotechnological advances, and breakthroughs in production and processing techniques. This text brings together essential information regarding the development and utilization of new fuels and bioproducts derived from sugarcane. Authored by experts in the field, Sugarcane-Based Biofuels and Bioproducts is an invaluable resource for researchers studying biofuels, sugarcane, and plant biotechnology as well as sugar and biofuels industry personnel.
Jesse Pines M. Evidence-Based Emergency Care. Diagnostic Testing and Clinical Decision Rules Jesse Pines M. Evidence-Based Emergency Care. Diagnostic Testing and Clinical Decision Rules Новинка

Jesse Pines M. Evidence-Based Emergency Care. Diagnostic Testing and Clinical Decision Rules

This book for emergency physicians and fellows training in emergency medicine provides evidence-based information on what diagnostic tests to ask for and when and how to use particular decision rules. The new edition builds on the success of the current book by modifying the presentation of the evidence, increasing the coverage, and updating the current information throughout.
Borisov S., Voronkov M., Lukevits E. Organosilicon Derivatives of Phosphorus and Sulfur Borisov S., Voronkov M., Lukevits E. Organosilicon Derivatives of Phosphorus and Sulfur Новинка

Borisov S., Voronkov M., Lukevits E. Organosilicon Derivatives of Phosphorus and Sulfur

One of the characteristics of the development of chemical science in the middle of the present century is the vigorous pro gress of the "third chemistry," which is often named now the chemistry of heteroorganic compounds. Then in the last decade, among specialists in this field there has been a marked increase in interest in heteroatomic organic derivatives of silicon, i. e. , heteroorganic silicon compounds. However, until recently this new class of chemical substances, which is extremely interesting theoretically and practically, has been without a single specialized monograph which systematizes and generalizes all progress in the heteroorganic chemistry of silicon. The first attempt in this direction was our book "Heteroorganic Compounds of Silicon" [42 (F), 17 (S) *], which appeared at the end of 1966 and was published as an English translation in the USA in 1969. However, as follows from its subtitle "Derivatives of Inorganic Elements," this mono graph could not cover the whole broad field of the chemistry of heteroorganic compounds of silicon. The main reason for this was above all the abundance and variety of original investigations of organosilicon derivatives of inorganic elements, which was un expected even to the authors themselves. As a result of this the planned length of the book compelled us to omit the sections on organosilicon compounds of phosphorus and sulfur, which had al ready been prepared for publication.Издательство - Plenum press
Juan Hinestroza Cellulose Based Composites. New Green Nanomaterials Juan Hinestroza Cellulose Based Composites. New Green Nanomaterials Новинка

Juan Hinestroza Cellulose Based Composites. New Green Nanomaterials

13377.33 руб. или Купить в рассрочку!
Aimed at researchers involved in this emerging field in both academia and industry, this book is unique in its focus on cellulose nanofibers, especially nano-composites, nanomoities and other plant based-resins and their composites. Despite its concise presentation, this handbook and ready reference provides a complete overview, containing such important topics as electrospinning, isolation, characterization and deposition of metallic nanoparticles.
Yoshiki Chujo Conjugated Polymer Synthesis. Methods and Reactions Yoshiki Chujo Conjugated Polymer Synthesis. Methods and Reactions Новинка

Yoshiki Chujo Conjugated Polymer Synthesis. Methods and Reactions

2169.35 руб. или Купить в рассрочку!
Edited and authored by top international experts, this first book on conjugated polymers with a focus on synthesis provides a detailed overview of all modern synthetic methods for these highly interesting compounds. As such, it describes every important compound class, including polysilanes, organoboron compounds, and ferrocene-containing conjugated polymers. An indispensable source for every synthetic polymer chemist.
William Buskist Evidence-Based Teaching. New Directions for Teaching and Learning, Number 128 William Buskist Evidence-Based Teaching. New Directions for Teaching and Learning, Number 128 Новинка

William Buskist Evidence-Based Teaching. New Directions for Teaching and Learning, Number 128

2203.72 руб. или Купить в рассрочку!
What could be more important to college and university faculty than teaching well? Indeed, in the past several years researchers have not only investigated key variables influencing teaching and learning, they also have applied empirical findings to develop and refine new systems of teaching and learning—approaches that provide the infrastructure for the day-to-day organization and assessment of student learning over the course of an academic term. This volume presents an overview of these systems and offers an assessment of the effectiveness of each relative to both student learning and enjoyment of the learning process. Written by leading teaching scholars, these systems include the lecture, problem-based learning, case studies, team-based learning, interteaching, service-learning, just-in-time teaching, Web-based computer-aided personalized instruction, and online teaching. Each contributor outlines the basic principles of a system, describes how to implement the system, and reviews the system’s overall effectiveness. This is the 128th volume of the Jossey-Bass higher education quarterly report New Directions for Teaching and Learning, which offers a comprehensive range of ideas and techniques for improving college teaching based on the experience of seasoned instructors and the latest findings of educational and psychological researchers.
Shahid Ul-Islam Plant-Based Natural Products. Derivatives and Applications Shahid Ul-Islam Plant-Based Natural Products. Derivatives and Applications Новинка

Shahid Ul-Islam Plant-Based Natural Products. Derivatives and Applications

14821.72 руб. или Купить в рассрочку!
Intense research has been started all around the world in the past few decades to exploit different agents from natural products as eco-friendly alternative to synthetic and toxic chemicals. Natural products and their derivatives have received increasing attention for their use in many everyday applications ranging from food, medicine, textiles, and healthcare.This new book presents significant research advances about the use of natural products, mainly plant colorants, bioactive compounds and other plant extracts in the textile coloration, food, bioremediation and environmental applications. There are total eight chapters contributed by leading researchers covering the topics such as potential resurgence of natural dyes in applied fields, natural colorants from indigoid plants, phytochemistry of dye yielding plants, irradiation as novel pretreatment methods, dyeing studies with henna plant, phytoremediation of arsenic, and synthesis of curcumin complexes for medicinal and other industrial uses.
Guo Zhongwu Carbohydrate-Based Vaccines and Immunotherapies Guo Zhongwu Carbohydrate-Based Vaccines and Immunotherapies Новинка

Guo Zhongwu Carbohydrate-Based Vaccines and Immunotherapies

12418.44 руб. или Купить в рассрочку!
The fundamental science and the latest developments in carbohydrate-based vaccines The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments. With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances. Key topics covered by Carbohydrate-Based Vaccines and Immunotherapies include: Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi Using adjuvants to improve immunogenicity and/or immunological properties of vaccines Choosing and designing proper adjuvants for specific targets Abnormal carbohydrates expressed by tumors Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy Clinical trials results for synthetic cancer vaccines Glycoengineering of cell surface carborhydrates and its anticancer applications Using cell surface carbohydrates for disease diagnosis A single, convenient source of state-of-the-art information from leading authorities in the field, Carbohydrate-Based Vaccines and Immunotherapies is an essential reference for organic chemists and biochemists, academic researchers, and other students and professionals involved in vaccine design.
Nagatoshi Nishiwaki Methods and Applications of Cycloaddition Reactions in Organic Syntheses Nagatoshi Nishiwaki Methods and Applications of Cycloaddition Reactions in Organic Syntheses Новинка

Nagatoshi Nishiwaki Methods and Applications of Cycloaddition Reactions in Organic Syntheses

15728.87 руб. или Купить в рассрочку!
Advanced tools for developing new functional materials and applications in chemical research, pharmaceuticals, and materials science Cycloadditions are among the most useful tools for organic chemists, enabling them to build carbocyclic and heterocyclic structures. These structures can then be used to develop a broad range of functional materials, including pharmaceuticals, agrochemicals, dyes, and optics. With contributions from an international team of leading experts and pioneers in cycloaddition chemistry, this book brings together and reviews recent advances, trends, and emerging research in the field. Methods and Applications of Cycloaddition Reactions in Organic Syntheses focuses on two component cycloadditions, with chapters covering such topics as: N1 unit transfer reaction to C–C double bonds [3+2] Cycloaddition of α, β-unsaturated metal-carbene complexes Formal [3+3] cycloaddition approach to natural product synthesis Development of new methods for the construction of heterocycles based on cycloaddition reaction of 1,3-dipoles Cycloreversion approach for preparation of large π-conjugated compounds Transition metal-catalyzed or mediated [5+1] cycloadditions Readers will learn methods for seamlessly executing important reactions such as Diels-Alder and stereoselective dipolar reactions in order to fabricate heterocyclic compounds, natural products, and functional molecules. The book not only features cutting-edge topics, but also important background information, such as the contributors’ process for developing new methodologies, to help novices become fully adept in the field. References at the end of each chapter lead to original research papers and reviews for facilitating further investigation of individual topics. Covering the state of the science and technology, Methods and Applications of Cycloaddition Reactions in Organic Syntheses enables synthetic organic chemists to advance their research and develop new functional materials and applications in chemical research, pharmaceuticals, and materials science.
Trabocchi Andrea Peptidomimetics in Organic and Medicinal Chemistry Trabocchi Andrea Peptidomimetics in Organic and Medicinal Chemistry Новинка

Trabocchi Andrea Peptidomimetics in Organic and Medicinal Chemistry

12806.52 руб. или Купить в рассрочку!
A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands. Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature. Topics covered include the chemistry of unnatural amino acids, peptide- and scaffold-based peptidomimetics, amino acid-side chain isosteres, backbone isosteres, dipeptide isosteres, beta-turn peptidomimetics, proline-mimetics as turn inducers, cyclic scaffolds, amino acid surrogates, and scaffolds for combinatorial chemistry of peptidomimetics. Case studies in the hit-to-lead process, such as the development of integrin ligands and thrombin inhibitors, illustrate the successful application of peptidomimetics in drug discovery.
Patrizia Diana Biosynthesis of Heterocycles. From Isolation to Gene Cluster Patrizia Diana Biosynthesis of Heterocycles. From Isolation to Gene Cluster Новинка

Patrizia Diana Biosynthesis of Heterocycles. From Isolation to Gene Cluster

15273.13 руб. или Купить в рассрочку!
This book describes biosynthetic methods to synthesize heterocyclic compounds, offering a guide for the development of new drugs based on natural products. The authors explain the role of natural products in chemistry and their formation along with important analytical methods and techniques for working with heterocycles. • Covers methods and techniques: isotopic labelling, enzymes and mutants, and pathway identification • Provides a thorough resource of information specifically on heterocyclic natural products and their practical biosynthetic relevance • Explains the role of natural products in chemistry and their formation • Discusses gene cluster identification and the use of biogenetic engineering in pharmaceutical application
Carolyn Schniering A. Evidence-Based CBT for Anxiety and Depression in Children and Adolescents. A Competencies Based Approach Carolyn Schniering A. Evidence-Based CBT for Anxiety and Depression in Children and Adolescents. A Competencies Based Approach Новинка

Carolyn Schniering A. Evidence-Based CBT for Anxiety and Depression in Children and Adolescents. A Competencies Based Approach

9041.29 руб. или Купить в рассрочку!
Evidence-Based CBT is the first book to take an explicitly competencies-based approach to the cognitive-behavioural treatment of anxiety and depression in children and young people. It draws on top-name expertise to define and demonstrate the therapist competencies needed to effectively implement CBT.
Mike Schneider Location Based Marketing For Dummies Mike Schneider Location Based Marketing For Dummies Новинка

Mike Schneider Location Based Marketing For Dummies

1616.34 руб. или Купить в рассрочку!
Learn to create a two-way dialog with customers with location-based services and smartphones Location-based services (LBS) have started to gain popularity in the marketplace with more and more businesses starting to incorporate LBS into their marketing mix. This book is a necessary resource for anyone eager to create a two-way dialog with their customers in order to establish customer loyalty programs, drive promotions, or encourage new visitors. You'll learn how to successfully build, launch, and measure a location-based marketing program and figure out which location-based services are right for your business. Packed with resources that share additional information, this helpful guide walks you through the tools and techniques needed to measure all the data that results from a successful location-based marketing program. Serves as an ideal introduction to location-based marketing and gets you started building a location-based marketing program Helps you figure out which location-based service (LBS) is right for your business and then integrate LBS with your social graph Details ways to create compelling offers, using location-based marketing as a customer loyalty program, and set performance goals and benchmarks Explains how to use tools to measure your campaign, analyze results, and determine your business's success Includes examples of companies that are successfully using location-based marketing to demonstrate techniques and concepts featured in the book No matter your location, location-based services can benefit your business and this For Dummies book shows you how!
William R. Dolbier, Jr. Guide to Fluorine NMR for Organic Chemists William R. Dolbier, Jr. Guide to Fluorine NMR for Organic Chemists Новинка

William R. Dolbier, Jr. Guide to Fluorine NMR for Organic Chemists

9500.64 руб. или Купить в рассрочку!
Following its well-received predecessor, this book offers an essential guide to chemists for understanding fluorine in spectroscopy. With over 1000 compounds and 100 spectra, the second edition adds new data – featuring fluorine effects on nitrogen NMR, chemical shifts, and coupling constants. • Explains how to successfully incorporate fluorine into target molecules and utilize fluorine substituents to structurally characterize organic compounds • Includes new data on nitrogen NMR, focusing on N-15, to portray the influence of fluorine upon nitrogen NMR chemical shifts and coupling constants • Expands on each chapter from the first edition with additional data and updated discussion from recent findings • «The flawless ordering of material covered in this stand-alone volume is such that information can be found very easily.» – Angewandte Chemie review of the first edition, 2010
Rankovic Zoran Lead Generation Approaches in Drug Discovery Rankovic Zoran Lead Generation Approaches in Drug Discovery Новинка

Rankovic Zoran Lead Generation Approaches in Drug Discovery

9469.06 руб. или Купить в рассрочку!
An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to improve the chances of finding such a compound. Written by leading scientists and established opinion leaders from industry and academia, this book provides an authoritative overview of the field, as well as the theory, practice, and scope, of the principal Lead Generation Approaches in Drug Discovery, including: The evolution of the lead discovery process, key concepts, current challenges, and future directions Strategies and technologies driving the high-throughput screening (HTS) approach to lead discovery, including the shifting paradigms in the design of compound collections and best practice in the hit confirmation process Knowledge-based in silico or «virtual» screening Theory and practice of the fragment-based approach to lead discovery The opportunities and challenges presented by multi-target drug discovery (MTDD) De novo design of lead compounds and new approaches to estimating the synthetic accessibility of de novo–designed molecules The impact of natural products on drug discovery, and potential of natural product–like compounds for exploring regions of biologically relevant chemical space Using early screening of hits and leads for metabolic, pharmacokinetic, and toxicological liabilities to reduce attrition during the later phases of drug discovery The utility of parallel synthesis and purification in lead discovery With each topic supported by numerous case studies, this is indispensable reading for researchers in industry and academia who wish to keep up to date with the latest strategies and approaches in drug discovery.
Toshio Fuchigami Fundamentals and Applications of Organic Electrochemistry. Synthesis, Materials, Devices Toshio Fuchigami Fundamentals and Applications of Organic Electrochemistry. Synthesis, Materials, Devices Новинка

Toshio Fuchigami Fundamentals and Applications of Organic Electrochemistry. Synthesis, Materials, Devices

7904.82 руб. или Купить в рассрочку!
This textbook is an accessible overview of the broad field of organic electrochemistry, covering the fundamentals and applications of contemporary organic electrochemistry. The book begins with an introduction to the fundamental aspects of electrode electron transfer and methods for the electrochemical measurement of organic molecules. It then goes on to discuss organic electrosynthesis of molecules and macromolecules, including detailed experimental information for the electrochemical synthesis of organic compounds and conducting polymers. Later chapters highlight new methodology for organic electrochemical synthesis, for example electrolysis in ionic liquids, the application to organic electronic devices such as solar cells and LEDs, and examples of commercialized organic electrode processes. Appendices present useful supplementary information including experimental examples of organic electrosynthesis, and tables of physical data (redox potentials of various organic solvents and organic compounds and physical properties of various organic solvents).
H. Huang K. PACS-Based Multimedia Imaging Informatics. Basic Principles and Applications H. Huang K. PACS-Based Multimedia Imaging Informatics. Basic Principles and Applications Новинка

H. Huang K. PACS-Based Multimedia Imaging Informatics. Basic Principles and Applications

18623.14 руб. или Купить в рассрочку!
Thoroughly revised to present the very latest in PACS-based multimedia in medical imaging informatics—from the electronic patient record to the full range of topics in digital medical imaging—this new edition by the founder of PACS and multimedia image informatics features even more clinically applicable material than ever before. It uses the framework of PACS-based image informatics, not physics or engineering principles, to explain PACS-based multimedia informatics and its application in clinical settings and labs. New topics include Data Grid and Cloud Computing, IHE XDS-I Workflow Profile (Integrating the Healthcare Enterprise Cross-enterprise Document Sharing for Imaging), extending XDS to share images, and diagnostic reports and related information across a group of enterprise health care sites. PACS-Based Multimedia Imaging Informatics is presented in 4 sections. Part 1 covers the beginning and history of Medical Imaging, PACS, and Imaging Informatics. The other three sections cover Medical Imaging, Industrial Guidelines, Standards, and Compliance; Informatics, Data Grid, Workstation, Radiation Therapy, Simulators, Molecular Imaging, Archive Server, and Cloud Computing; and multimedia Imaging Informatics, Computer-Aided Diagnosis (CAD), Image-Guide Decision Support, Proton Therapy, Minimally Invasive Multimedia Image-Assisted Surgery, BIG DATA. New chapter on Molecular Imaging Informatics Expanded coverage of PACS and eHR's (Electronic Health Record), with HIPPA compliance New coverage of PACS-based CAD (Computer-Aided Diagnosis) Reorganized and expanded clinical chapters discuss one distinct clinical application each Minimally invasive image assisted surgery in translational medicine Authored by the world's first and still leading authority on PACS and medical imaging PACS-Based Multimedia Imaging Informatics: Basic Principles and Applications, 3rd Edition is the single most comprehensive and authoritative resource that thoroughly covers the critical issues of PACS-based hardware and software design and implementation in a systematic and easily comprehensible manner. It is a must-have book for all those involved in designing, implementing, and using PACS-based Multimedia Imaging Informatics.
Viktor Zhdankin V. Hypervalent Iodine Chemistry. Preparation, Structure, and Synthetic Applications of Polyvalent Iodine Compounds Viktor Zhdankin V. Hypervalent Iodine Chemistry. Preparation, Structure, and Synthetic Applications of Polyvalent Iodine Compounds Новинка

Viktor Zhdankin V. Hypervalent Iodine Chemistry. Preparation, Structure, and Synthetic Applications of Polyvalent Iodine Compounds

13833.07 руб. или Купить в рассрочку!
Hypervalent Iodine Chemistry is the first comprehensive text covering all of the main aspects of the chemistry of organic and inorganic polyvalent iodine compounds, including applications in chemical research, medicine, and industry. Providing a comprehensive overview of the preparation, properties, and synthetic applications of this important class of reagents, the text is presented in the following way: The introductory chapter provides a historical background and describes the general classification of iodine compounds, nomenclature, hypervalent bonding, structural features, and the principles of reactivity of polyvalent iodine compounds. Chapter 2 gives a detailed description of the preparative methods and structural features of all known classes of organic and inorganic derivatives of polyvalent iodine. Chapter 3, the key chapter of the book, deals with the many applications of hypervalent iodine reagents in organic synthesis. Chapter 4 describes the most recent achievements in hypervalent iodine catalysis. Chapter 5 deals with recyclable polymer-supported and nonpolymeric hypervalent iodine reagents. Chapter 6 covers the «green» reactions of hypervalent iodine reagents under solvent-free conditions or in aqueous solutions. The final chapter provides an overview of the important practical applications of polyvalent iodine compounds in medicine and industry. This book is aimed at all chemists interested in iodine compounds, including academic and industrial researchers in inorganic, organic, physical, medicinal, and biological chemistry. It will be particularly useful to synthetic organic and inorganic chemists, including graduate and advanced undergraduate students. It comprehensively covers the green chemistry aspects of hypervalent iodine chemistry, making it especially useful for industrial chemists.
Antonio Dans L. Painless Evidence-Based Medicine Antonio Dans L. Painless Evidence-Based Medicine Новинка

Antonio Dans L. Painless Evidence-Based Medicine

3530.56 руб. или Купить в рассрочку!
This updated edition of Painless Evidence-Based Medicine presents basic concepts and application of research statistics in simple and practical manner creating an introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers. A simplified introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers Approaches learning from the vantage point of clinical questions on therapy, diagnosis, prognosis or harm rather than the framework of study designs Provides tables and boxed case studies throughout highlighting key topics, or difficult issues, in an easy to read manner Emphasizes applicability of EBM, encouraging readers to dissect the evidence and how results can be applied to individual patients with different circumstances, varying values and preferences New to the Second Edition are chapters on health screening, clinical practice guidelines, and major updates incorporating recommended trial criteria
Oleg Kulinkovich G. Cyclopropanes in Organic Synthesis Oleg Kulinkovich G. Cyclopropanes in Organic Synthesis Новинка

Oleg Kulinkovich G. Cyclopropanes in Organic Synthesis

13300.89 руб. или Купить в рассрочку!
This is a practical guidebook about cyclopropanes that thoroughly surveys derivatives and transformations, synthetic methods, and experimental efficiency as a gateway for further research and development in the field. • Provides comprehensive lists and synthetically-oriented synopses of cyclopropane chemistry review references along with publication data on applications in the syntheses of natural and related biologically active compounds • Acts as a resource to help readers better understand cyclopropane applications for the efficient realization of synthetically important organic transformations and popular experimental procedures • Includes new developments and up-to-date information that will lead to original methodologies for complex organic synthesis • Stresses universality, flexibility, and experimental efficiency of a strategy based on preparing cyclopropane derivatives and performing ring cleavage reactions with inexpensive reagents • Focuses on the synthetic potential of cyclopropane applications, for example the synthesis of natural compounds and other target-oriented syntheses via cyclopropane intermediaries, as well on their planning by retrosynthetic analysis
David Keefe Evidence-based Obstetrics and Gynecology David Keefe Evidence-based Obstetrics and Gynecology Новинка

David Keefe Evidence-based Obstetrics and Gynecology

16764.9 руб. или Купить в рассрочку!
The most comprehensive evidence-based guide to both obstetrics and gynecology Aimed at practicing obstetricians, gynecologists, and trainees in the specialty, Evidence-based Obstetrics and Gynecology concentrates on the clinical practice areas of diagnosis, investigation and management. The first section of the book discusses evidence-based medicine methodology in the context of the two specialties. The second and third sections cover all the major conditions in obstetrics and gynecology, with each chapter reviewing the best available evidence for management of the particular condition. The chapters are structured in line with EBM methodology, meaning the cases generate the relevant clinical questions. Evidence-based Obstetrics and Gynecology provides in-depth chapter coverage of abnormal vaginal bleeding; ectopic pregnancy; pelvic pain; lower genital tract infections; contraception and sterilization; breast diseases; urogynecology; endocrinology and infertility; puberty and precocious puberty; cervical dysplasia and HPV; cervical, vaginal, vulvar, uterine, and ovarian cancer; preconception care; prenatal care and diagnosis; drugs and medications in pregnancy; maternal complications; chronic hypertension; diabetes mellitus; thyroid disease; neurologic disease; psychiatric disease; postterm pregnancy; fetal complications; preeclampsia; and more. First book to address evidence-based practice for obstetrics and gynecology combined EBM is a highly relevant approach for this high risk specialty Edited by leading US specialist involved in the evidence-based medicine movement Evidence-Based Obstetrics and Gynecology is an important text for obstetricians and gynecologists in practice and in training, as well as for specialist nurses.

кешбака
Страницы:


A comprehensive compilation of the available experimental and theoretical vibrational data for organometallic compounds and its role in evaluating the structures, bonding, and properties of these key compounds This unique book offers a thorough review of the literature dealing with vibrational data obtained using various phases, including matrices, reported for organometallic compounds from infrared spectra, Raman spectra, and several other techniques. It is the only one that compiles the available experimental and theoretical vibrational data on these compounds, and which discusses the importance of this information and its role in evaluating structures, bonding, and other important properties. It also treats the use of DFT and other theoretical calculations to analyze the vibrational data and to predict properties associated with these compounds. The book also includes vibrational data for organic species that form on metal and other surfaces. Vibrational Spectra of Organometallics: Theoretical and Experimental Data offers complete coverage of: Carbide, Alkylidyne, Alkylidene, Alkyl, and Alkane Derivatives; Noncyclic Carbon‐Clusters and Unsaturated Hydrocarbon Derivatives; and Cyclic, Unsaturated Organometallic Derivatives. By summarizing work that has already been done on organometallic compounds, it serves as an important reference for those studying their vibrational spectra and will, in the end, lead to a clearer understanding of other research that needs to be done in order to help researchers determine new research directions. An important reference for those studying the vibrational spectra of organometallic compounds Gathers the existing experimental and theoretical vibrational data and discusses its significance in assessing structures, bonding, and other principle properties Includes DFT methods for the interpretation of spectra, which has been one of the major developments of the last two decades Vibrational Spectra of Organometallics: Theoretical and Experimental Data is an important reference for researchers and practitioners in the areas of inorganic, organometallic, organic, and surface chemistry who have an interest in using vibrational data to characterize the bonding, composition, reactions, and structures of organometallic compounds, and organic species that are formed on various surfaces.
Продажа new carbazole indole and diphenylamine based emissive compounds лучших цены всего мира
Посредством этого сайта магазина - каталога товаров мы очень легко осуществляем продажу new carbazole indole and diphenylamine based emissive compounds у одного из интернет-магазинов проверенных фирм. Определитесь с вашими предпочтениями один интернет-магазин, с лучшей ценой продукта. Прочитав рекомендации по продаже new carbazole indole and diphenylamine based emissive compounds легко охарактеризовать производителя как превосходную и доступную фирму.