pharmaceutical determination of gemifloxacin by using hplc dad



Birendra Pramanik Characterization of Impurities and Degradants Using Mass Spectrometry Birendra Pramanik Characterization of Impurities and Degradants Using Mass Spectrometry Новинка

Birendra Pramanik Characterization of Impurities and Degradants Using Mass Spectrometry

9652.79 руб. или Купить в рассрочку!
The book highlights the current practices and future trends in structural characterization of impurities and degradants. It begins with an overview of mass spectrometry techniques as related to the analysis of impurities and degradants, followed by studies involving characterization of process related impurities (including potential genotoxic impurities), and excipient related impurities in formulated products. Both general practitioners in pharmaceutical research and specialists in analytical chemistry field will benefit from this book that will detail step-by-step approaches and new strategies to solve challenging problems related to pharmaceutical research.
Lloyd Snyder R. Introduction to Modern Liquid Chromatography Lloyd Snyder R. Introduction to Modern Liquid Chromatography Новинка

Lloyd Snyder R. Introduction to Modern Liquid Chromatography

11629.36 руб. или Купить в рассрочку!
The latest edition of the authoritative reference to HPLC High-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples. This carefully considered Third Edition maintains the strengths of the previous edition while significantly modifying its organization in light of recent research and experience. The text begins by introducing the reader to HPLC, its use in relation to other modern separation techniques, and its history, then leads into such specific topics as: The basis of HPLC separation and the general effects of different experimental conditions Equipment and detection The column—the «heart» of the HPLC system Reversed-phase separation, normal-phase chromatography, gradient elution, two-dimensional separation, and other techniques Computer simulation, qualitative and quantitative analysis, and method validation and quality control The separation of large molecules, including both biological and synthetic polymers Chiral separations, preparative separations, and sample preparation Systematic development of HPLC separations—new to this edition Troubleshooting tricks, techniques, and case studies for both equipment and chromatograms Designed to fulfill the needs of the full range of HPLC users, from novices to experts, Introduction to Modern Liquid Chromatography, Third Edition offers the most up-to-date, comprehensive, and accessible survey of HPLC methods and applications available.
Gaisford Simon Essentials of Pharmaceutical Preformulation Gaisford Simon Essentials of Pharmaceutical Preformulation Новинка

Gaisford Simon Essentials of Pharmaceutical Preformulation

12030.37 руб. или Купить в рассрочку!
Essentials of Pharmaceutical Preformulation is a study guide which describes the basic principles of pharmaceutical physicochemical characterisation. Successful preformulation requires knowledge of fundamental molecular concepts (solubility, ionisation, partitioning, hygroscopicity and stability) and macroscopic properties (physical form, such as the crystalline and amorphous states, hydrates, solvates and co-crystals and powder properties), familiarity with the techniques used to measure them and appreciation of their effect on product performance, recognising that often there is a position of compromise to be reached between product stability and bioavailability. This text introduces the basic concepts and discusses their wider implication for pharmaceutical development, with reference to many case examples of current drugs and drug products. Special attention is given to the principles and best-practice of the analytical techniques that underpin preformulation (UV spectrophotometry, TLC, DSC, XRPD and HPLC). The material is presented in the typical order that would be followed when developing a medicine and maps onto the indicative pharmacy syllabus of the Royal Pharmaceutical Society of Great Britain Undergraduate-level pharmacy students and R&D / analytical scientists working in the pharmaceutical sector (with or without a pharmaceutical background) will find this text easy to follow with relevant pharmaceutical examples. Essential study guide for pharmacy and pharmaceutical science students Covers the pharmaceutical preformulation components of the Royal Pharmaceutical Society of Great Britain’s indicative syllabus Easy to follow text highlighted with relevant pharmaceutical examples Self-assessment assignments in a variety of formats Written by authors with both academic and industrial experience Companion website with further information to maximise learning
John Nash C. Nonlinear Parameter Optimization Using R Tools John Nash C. Nonlinear Parameter Optimization Using R Tools Новинка

John Nash C. Nonlinear Parameter Optimization Using R Tools

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Nonlinear Parameter Optimization Using R John C. Nash, Telfer School of Management, University of Ottawa, Canada A systematic and comprehensive treatment of optimization software using R In recent decades, optimization techniques have been streamlined by computational and artificial intelligence methods to analyze more variables, especially under non–linear, multivariable conditions, more quickly than ever before. Optimization is an important tool for decision science and for the analysis of physical systems used in engineering. Nonlinear Parameter Optimization with R explores the principal tools available in R for function minimization, optimization, and nonlinear parameter determination and features numerous examples throughout. Nonlinear Parameter Optimization with R: Provides a comprehensive treatment of optimization techniques Examines optimization problems that arise in statistics and how to solve them using R Enables researchers and practitioners to solve parameter determination problems Presents traditional methods as well as recent developments in R Is supported by an accompanying website featuring R code, examples and datasets Researchers and practitioners who have to solve parameter determination problems who are users of R but are novices in the field optimization or function minimization will benefit from this book. It will also be useful for scientists building and estimating nonlinear models in various fields such as hydrology, sports forecasting, ecology, chemical engineering, pharmaco-kinetics, agriculture, economics and statistics.
Stavros Kromidas The HPLC-Expert II. Optimizing the Benefits of HPLC/UHPLC Stavros Kromidas The HPLC-Expert II. Optimizing the Benefits of HPLC/UHPLC Новинка

Stavros Kromidas The HPLC-Expert II. Optimizing the Benefits of HPLC/UHPLC

8360.56 руб. или Купить в рассрочку!
How can I use my HPLC/UHPLC equipment in an optimal way, where are the limitations of the technique? These questions are discussed in detail in the sequel of the successful «HPLC Expert» in twelve chapters written by experts in the respective fields. The topics encompass – complementary to the first volume – typical HPLC users' problems and questions such as gradient optimization and hyphenated techniques (LC-MS). An important key aspect of the book is UHPLC: For which analytical problem is it essential, what should be considered? Besides presentation of latest developments directly from the main manufacturers, also UHPLC users and independent service engineers impart their knowledge. Consistent with the target groups, the level is advanced, but the emphasis is on practical applications.
Stavros Kromidas The HPLC-MS Handbook for Practitioners Stavros Kromidas The HPLC-MS Handbook for Practitioners Новинка

Stavros Kromidas The HPLC-MS Handbook for Practitioners

8360.56 руб. или Купить в рассрочку!
Filling the gap for an expert text dealing exclusively with the practical aspects of HPLC-MS coupling, this concise, compact, and clear book provides detailed information to enable users to employ the method most efficiently. Following an overview of the current state of HPLC-MS and its instrumentation, the text goes on to discuss all relevant aspects of method development. A chapter on tips and tricks is followed by user reports on the advantages – and pitfalls – of applying the method in real-life scenarios. The whole is rounded off by a look at future developments by renowned manufacturers.
Dennis Douroumis Hot-Melt Extrusion. Pharmaceutical Applications Dennis Douroumis Hot-Melt Extrusion. Pharmaceutical Applications Новинка

Dennis Douroumis Hot-Melt Extrusion. Pharmaceutical Applications

14902.13 руб. или Купить в рассрочку!
Hot-melt extrusion (HME) – melting a substance and forcing it through an orifice under controlled conditions to form a new material – is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science. This is the first book from our brand new series Advances in Pharmaceutical Technology. Find out more about the series here.
John Posner The Textbook of Pharmaceutical Medicine John Posner The Textbook of Pharmaceutical Medicine Новинка

John Posner The Textbook of Pharmaceutical Medicine

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The Textbook of Pharmaceutical Medicine is the standard reference for everyone working and learning in pharmaceutical medicine. It is a comprehensive resource covering the processes and practices by which medicines are developed, tested and approved, and the recognised text for the Diploma in Pharmaceutical Medicine from the Faculty of Pharmaceutical Medicine. This fully revised Seventh Edition, which includes two new Editors, encompasses current developments within pharmaceutical medicine with new chapters on biological therapeutics, pharmacovigilance, vaccines, drugs for cancer, drug development in paediatrics and neonatalogy, the clinical trials directive, life cycle management of medicines, counterfeit medicines and medical marketing. Also included for easy reference, and referred to throughout the text, are the Declaration of Helsinki, Guidelines and Documentation for Implementation of Clinical Trials, relevant European Directives and the Syllabus for Pharmaceutical Medicine. Written by an international team of leading academics, medical directors and lawyers, The Textbook of Pharmaceutical Medicine, Seventh Edition meets the needs of both those working in pharmaceutical medicine and preparing for the Diploma in Pharmaceutical Medicine. The text breaks down into three core sections: Part I: Research and Development Part II: Regulation Part III: Healthcare marketplace View Table of Contents in detail
Satinder Ahuja Chiral Separation Methods for Pharmaceutical and Biotechnological Products Satinder Ahuja Chiral Separation Methods for Pharmaceutical and Biotechnological Products Новинка

Satinder Ahuja Chiral Separation Methods for Pharmaceutical and Biotechnological Products

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Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.
Philip Rowe Essential Statistics for the Pharmaceutical Sciences Philip Rowe Essential Statistics for the Pharmaceutical Sciences Новинка

Philip Rowe Essential Statistics for the Pharmaceutical Sciences

Essential Statistics for the Pharmaceutical Sciences is targeted at all those involved in research in pharmacology, pharmacy or other areas of pharmaceutical science; everybody from undergraduate project students to experienced researchers should find the material they need. This book will guide all those who are not specialist statisticians in using sound statistical principles throughout the whole journey of a research project – designing the work, selecting appropriate statistical methodology and correctly interpreting the results. It deliberately avoids detailed calculation methodology. Its key features are friendliness and clarity. All methods are illustrated with realistic examples from within pharmaceutical science. This edition now includes expanded coverage of some of the topics included in the first edition and adds some new topics relevant to pharmaceutical research. a clear, accessible introduction to the key statistical techniques used within the pharmaceutical sciences all examples set in relevant pharmaceutical contexts. key points emphasised in summary boxes and warnings of potential abuses in ‘pirate boxes’. supplementary material – full data sets and detailed instructions for carrying out analyses using packages such as SPSS or Minitab – provided at www.ljmu.ac.uk/pbs/rowestats/ An invaluable introduction to statistics for any science student and an essential text for all those involved in pharmaceutical research at whatever level.
A Summary of Rich Dad Poor Dad A Summary of Rich Dad Poor Dad Новинка

A Summary of Rich Dad Poor Dad

"Rich Dad, Poor Dad: What The Rich Teach Their Kids About Money--That The Poor And The Middle Class Do Not!," by Robert T. Kiyosaki, compares the financial philosophies of the author's two fathers: his biological father - the poor dad - and the father of his childhood best friend, Mike - the rich dad. Throughout the book the author compares both fathers, and how his real father, the poor and struggling but highly educated man, paled against his rich dad in terms of asset building and business acumen.- Save time on the go with the compact format and concise summary- Explore key quotations from the book
Thomas Ryan P. Sample Size Determination and Power Thomas Ryan P. Sample Size Determination and Power Новинка

Thomas Ryan P. Sample Size Determination and Power

A comprehensive approach to sample size determination and power with applications for a variety of fields Sample Size Determination and Power features a modern introduction to the applicability of sample size determination and provides a variety of discussions on broad topics including epidemiology, microarrays, survival analysis and reliability, design of experiments, regression, and confidence intervals. The book distinctively merges applications from numerous fields such as statistics, biostatistics, the health sciences, and engineering in order to provide a complete introduction to the general statistical use of sample size determination. Advanced topics including multivariate analysis, clinical trials, and quality improvement are addressed, and in addition, the book provides considerable guidance on available software for sample size determination. Written by a well-known author who has extensively class-tested the material, Sample Size Determination and Power: Highlights the applicability of sample size determination and provides extensive literature coverage Presents a modern, general approach to relevant software to guide sample size determination including CATD (computer-aided trial design) Addresses the use of sample size determination in grant proposals and provides up-to-date references for grant investigators An appealing reference book for scientific researchers in a variety of fields, such as statistics, biostatistics, the health sciences, mathematics, ecology, and geology, who use sampling and estimation methods in their work, Sample Size Determination and Power is also an ideal supplementary text for upper-level undergraduate and graduate-level courses in statistical sampling.
Innovation in the Pharmaceutical Industry: The Process of Drug Discovery and Development Innovation in the Pharmaceutical Industry: The Process of Drug Discovery and Development Новинка

Innovation in the Pharmaceutical Industry: The Process of Drug Discovery and Development

Book DescriptionInnovation in the Pharmaceutical Industry traces the discovery and development of drugs in Japan and the UK both historically and sociologically. It includes sixteen case studies of major pharmaceutical developments in the twentieth century, encompassing, among others, beta-blockers, beta-stimulants, inhaled steroids and histamine H2-antagonists. The book illustrates that the four stages of drug development - namely compound, application, organizational authorization and market - are interactively shaped by heterogeneous actors and institutions. The book also identifies three different types of pharmaceutical development - paradigmatic innovation, application innovation and modification-based innovation, all with distinguishable features in the drug development process. Finally, several historical, structural and cultural factors influencing the shaping of medicines are revealed by the comparison between British and Japanese drug innovation. Addressing a number of practical implications for the promotion of the pharmaceutical industry, this book will be of enormous interest to students, researchers and academics specializing in science and technology, and the management of technology and innovation. Practitioners, managers, and policy planners within the pharmaceutical industry will also deem this book invaluable.
Degryse Patrick Isotopic Analysis. Fundamentals and Applications Using ICP-MS Degryse Patrick Isotopic Analysis. Fundamentals and Applications Using ICP-MS Новинка

Degryse Patrick Isotopic Analysis. Fundamentals and Applications Using ICP-MS

10322.83 руб. или Купить в рассрочку!
Edited by two very well-known and respected scientists in the field, this excellent practical guide is the first to cover the fundamentals and a wide range of applications, as well as showing readers how to efficiently use this increasingly important technique. From the contents: * The Isotopic Composition of the Elements * Single-Collector ICP-MS * Multi-Collector ICP-MS * Advances in Laser Ablation – Multi-Collector ICP-MS * Correction for Instrumental Mass Discrimination in Isotope Ratio Determination with Multi-Collector ICP-MS * Reference Materials in Isotopic Analysis * Quality Control in Isotope Ratio Applications * Determination of Trace Elements and Elemental Species Using Isotope Dilution ICP-MS * Geochronological Dating * Application of Multi-Collector ICP-MS to Isotopic Analysis in Cosmochemistry * Establishing the Basis for Using Stable Isotope Ratios of Metals as Paleoredox Proxies * Isotopes as Tracers of Elements Across the Geosphere-Biosphere Interface * Archaeometric Applications * Forensics Applications * Nuclear Applications * The Use of Stable Isotope Techniques for Studying Mineral and Trace Element Metabolism in Humans * Isotopic Analysis via Multi-Collector ICP-MS in Elemental Speciation A must-have for newcomers as well as established scientists seeking an overview of isotopic analysis via ICP-MS.
Dennis Jenke Compatibility of Pharmaceutical Solutions and Contact Materials. Safety Assessments of Extractables and Leachables for Pharmaceutical Products Dennis Jenke Compatibility of Pharmaceutical Solutions and Contact Materials. Safety Assessments of Extractables and Leachables for Pharmaceutical Products Новинка

Dennis Jenke Compatibility of Pharmaceutical Solutions and Contact Materials. Safety Assessments of Extractables and Leachables for Pharmaceutical Products

10866.14 руб. или Купить в рассрочку!
Compatibility of Pharmaceutical Products and Contact Materials Dennis Jenke Important safety aspects of compatibility for therapeutic products and their manufacturing systems, delivery devices, and containers Compatibility of Pharmaceutical Products and Contact Materials helps pharmaceutical, toxicology, analytical, and regulatory affairs professionals assess the safety of leachable and extractable chemicals associated with drug product packaging, manufacturing systems, and devices. The most comprehensive resource available, its coverage includes the strategies, tactics, and regulatory requirements for performing safety assessments, along with the means for interpreting results. Structured around a logical framework for an extractables and leachables safety assessment and closely linked to the pharmaceutical product development process, Compatibility of Pharmaceutical Products and Contact Materials directly addresses the fundamental questions of «what activities need to be performed to completely, efficiently, and effectively address the issue of product safety from an extractables and leachables perspective?» and «when do the various required activities need to be performed?» Specifically, the chapters describe: Pertinent regulations and practical ways to meet guidelines Coordinating manufacturing, storage, and delivery systems development and qualification with therapeutic product development Materials characterization and the materials screening process Component and/or system qualification (illustrated by several case studies) Performing validation/migration studies and interpreting and reporting the results Creating a product registration dossier and putting it through regulatory review Product maintenance (Change Control) from an extractables and leachables perspective Likely future developments in extractables and leachables assessment Additionally, the book's appendix provides a database, including CAS registry numbers, chemical formulas and molecular weights of extractable/leachable substances that have been reported in the chemical literature. Detailing the interconnected roles played by analytical chemistry, biological science, toxicology, and regulatory science, Compatibility of Pharmaceutical Products and Contact Materials supplies a much-needed, comprehensive resource to all those in pharmaceutical product or medical device development.
Behnam Davani Pharmaceutical Analysis for Small Molecules Behnam Davani Pharmaceutical Analysis for Small Molecules Новинка

Behnam Davani Pharmaceutical Analysis for Small Molecules

9500.64 руб. или Купить в рассрочку!
A comprehensive introduction for scientists engaged in new drug development, analysis, and approvals Each year the pharmaceutical industry worldwide recruits thousands of recent science graduates—especially chemistry, analytical chemistry, pharmacy, and pharmaceutical majors—into its ranks. However, because of their limited background in pharmaceutical analysis most of those new recruits find making the transition from academia to industry very difficult. Designed to assist both recent graduates, as well as experienced chemists or scientists with limited regulatory, compendial or pharmaceutical analysis background, make that transition, Pharmaceutical Analysis for Small Molecules is a concise, yet comprehensive introduction to the drug development process and analysis of chemically synthesized, small molecule drugs. It features contributions by distinguished experts in the field, including editor and author, Dr. Behnam Davani, an analytical chemist with decades of technical management and teaching experience in compendial, regulatory, and industry. This book provides an introduction to pharmaceutical analysis for small molecules (non-biologics) using commonly used techniques for drug characterization and performance tests. The driving force for industry to perform pharmaceutical analyses is submission of such data and supporting documents to regulatory bodies for drug approval in order to market their products. In addition, related required supporting studies including good laboratory/documentation practices including analytical instrument qualification are highlighted in this book. Topics covered include: Drug Approval Process and Regulatory Requirements (private standards) Pharmacopeias and Compendial Approval Process (public standards) Common methods in pharmaceutical analysis (typically compendial) Common Calculations for assays and impurities and other specific tests Analytical Method Validation, Verification, Transfer Specifications including how to handle out of specification (OOS) and out of trend (OOT) Impurities including organic, inorganic, residual solvents and elemental impurities Good Documentation Practices for regulatory environment Management of Analytical Laboratories Analytical Instrument Qualifications including IQ, OQ, PQ and VQ Due to global nature of pharmaceutical industry, other topics on both regulatory (ICH) and Compendial harmonization are also highlighted. Pharmaceutical Analysis for Small Molecules is a valuable working resource for scientists directly or indirectly involved with the drug development process, including analytical chemists, pharmaceutical scientists, pharmacists, and quality control/quality assurance professionals. It also is an excellent text/reference for graduate students in analytical chemistry, pharmacy, pharmaceutical and regulatory sciences.
Stanley Sandler I. Using Aspen Plus in Thermodynamics Instruction. A Step-by-Step Guide Stanley Sandler I. Using Aspen Plus in Thermodynamics Instruction. A Step-by-Step Guide Новинка

Stanley Sandler I. Using Aspen Plus in Thermodynamics Instruction. A Step-by-Step Guide

5696.78 руб. или Купить в рассрочку!
A step-by-step guide for students (and faculty) on the use of Aspen in teaching thermodynamics • Easily-accessible modern computational techniques opening up new vistas in teaching thermodynamics A range of applications of Aspen Plus in the prediction and calculation of thermodynamic properties and phase behavior using the state-of-the art methods • Encourages students to develop engineering insight by doing repetitive calculations with changes in parameters and/or models • Calculations and application examples in a step-by-step manner designed for out-of-classroom self study • Makes it possible to easily integrate Aspen Plus into thermodynamics courses without using in-class time • Stresses the application of thermodynamics to real problems
Alain Boutier Laser Metrology in Fluid Mechanics. Granulometry, Temperature and Concentration Measurements Alain Boutier Laser Metrology in Fluid Mechanics. Granulometry, Temperature and Concentration Measurements Новинка

Alain Boutier Laser Metrology in Fluid Mechanics. Granulometry, Temperature and Concentration Measurements

14514.06 руб. или Купить в рассрочку!
In fluid mechanics, non-intrusive measurements are fundamental in order to improve knowledge of the behavior and main physical phenomena of flows in order to further validate codes. The principles and characteristics of the different techniques available in laser metrology are described in detail in this book. Velocity, temperature and concentration measurements by spectroscopic techniques based on light scattered by molecules are achieved by different techniques: laser-induced fluorescence, coherent anti-Stokes Raman scattering using lasers and parametric sources, and absorption spectroscopy by tunable laser diodes, which are generally better suited for high velocity flows. The size determination of particles by optical means, a technique mainly applied in two-phase flows, is the subject of another chapter, along with a description of the principles of light scattering. For each technique the basic principles are given, as well as optical devices and data processing. A final chapter reminds the reader of the main safety precautions to be taken when using powerful lasers.
Norman Hodges A. Hugo and Russell's Pharmaceutical Microbiology Norman Hodges A. Hugo and Russell's Pharmaceutical Microbiology Новинка

Norman Hodges A. Hugo and Russell's Pharmaceutical Microbiology

Pharmaceutical microbiology has a bearing on all aspects of pharmacy, from the manufacture and quality control of pharmaceutical products through to an understanding of the mode of action of antibiotics. Fully revised and restructured, drawing on the contributions of subject experts, and including material relevant to the European curricula in pharmacy, the eighth edition covers: biology of micro-organisms pathogens and host response prescribing therapeutics contamination and infection control pharmaceutical production current trends and new directions Hugo and Russell’s Pharmaceutical Microbiology, a standard text for Schools of Pharmacy for seven editions, continues to be a user-friendly and authoritative guide for both students and practitioners of pharmacy and pharmaceutical microbiology. 'Highly Commended' in the Pharmacology section of the 2012 BMA Book Awards
Mark Vitha F. Hydrophilic Interaction Chromatography. A Guide for Practitioners Mark Vitha F. Hydrophilic Interaction Chromatography. A Guide for Practitioners Новинка

Mark Vitha F. Hydrophilic Interaction Chromatography. A Guide for Practitioners

8432.67 руб. или Купить в рассрочку!
Discover how to use HILIC to analyze and better understand polar compounds An increasingly popular analytical method, hydrophilic interaction chromatography (HILIC) has the ability to retain and separate polar compounds that are often difficult to analyze by reversed-phase high-performance liquid chromatography (HPLC) or other analytical methods. Offering a comprehensive review, this book enables readers to develop a fundamental understanding of how HILIC works and then apply that knowledge to develop and implement a variety of practical applications. Hydrophilic Interaction Chromatography begins with discussions of HILIC retention mechanisms, stationary phases, and general method development. This sets the foundation for the book's extensive coverage of applications. The authors address unique separation challenges for bioanalytical, environmental, pharmaceutical, and biochemical applications. Moreover, there is a thorough discussion of HILIC in two-dimensional chromatography. With contributions from leading analytical scientists who have extensive experience in HILIC as well as HPLC, Hydrophilic Interaction Chromatography serves as a practical guide for researchers, featuring: Detailed examples of HILIC methods and development approaches Thorough explanations of retention mechanisms and the impact of stationary phase and mobile phase properties on separations Step-by-step guidance for developing efficient, sensitive, and robust HILIC methods References to the primary literature at the end of each chapter Hydrophilic Interaction Chromatography is written for scientists who use or develop analytical methods for the separation of polar compounds. In particular, these researchers will discover how HILIC can be used to analyze and better understand the composition of pharmaceutical, bioanalytical, biochemical, chemical, food, and environmental samples.
Robin Harris K. NMR in Pharmaceutical Science Robin Harris K. NMR in Pharmaceutical Science Новинка

Robin Harris K. NMR in Pharmaceutical Science

NMR in Pharmaceutical Sciences is intended to be a comprehensive source of information for the many individuals that utilize MR in studies of relevance to the pharmaceutical sector. The book is intended to educate and inform those who develop and apply MR approaches within the wider pharmaceutical environment, emphasizing the toolbox that is available to spectroscopists and radiologists. This book is structured on the key processes in drug discovery, development and manufacture, but underpinned by an understanding of fundamental NMR principles and the unique contribution that NMR (including MRI) can provide. After an introductory chapter, which constitutes an overview, the content is organised into five sections. The first section is on the basics of NMR theory and relevant experimental methods. The rest follow a sequence based on the chronology of drug discovery and development, firstly 'Idea to Lead' then 'Lead to Drug Candidate', followed by 'Clinical Development', and finally 'Drug Manufacture'. The thirty one chapters cover a vast range of topics from analytical chemistry, including aspects involved in regulatory matters and in the prevention of fraud, to clinical imaging studies. Whilst this comprehensive volume will be essential reading for many scientists based in pharmaceutical and related industries, it should also be of considerable value to a much wider range of academic scientists whose research is related to the various aspects of pharmaceutical R&D; for them it will supply vital understanding of pharmaceutical industrial concerns and the basis of key decision making processes. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes
Lionel Edwards D. Principles and Practice of Pharmaceutical Medicine Lionel Edwards D. Principles and Practice of Pharmaceutical Medicine Новинка

Lionel Edwards D. Principles and Practice of Pharmaceutical Medicine

27362.56 руб. или Купить в рассрочку!
The new edition of Principles and Practice of Pharmaceutical Medicine is a comprehensive reference guide to all aspects of pharmaceutical medicine. New content includes chapters and coverage on regulatory updates, increasing international harmonization, transitional and probabilistic approaches to drug development, the growing sophistication and regulatory importance of pharmacovigilance, personalized medicine and growth in biotechnology as a source of new experimental drugs.
Stig Pedersen-Bjergaard Introduction to Pharmaceutical Chemical Analysis Stig Pedersen-Bjergaard Introduction to Pharmaceutical Chemical Analysis Новинка

Stig Pedersen-Bjergaard Introduction to Pharmaceutical Chemical Analysis

16265.38 руб. или Купить в рассрочку!
This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples
Hansen Neal Pharmaceutical Lifecycle Management. Making the Most of Each and Every Brand Hansen Neal Pharmaceutical Lifecycle Management. Making the Most of Each and Every Brand Новинка

Hansen Neal Pharmaceutical Lifecycle Management. Making the Most of Each and Every Brand

7680.03 руб. или Купить в рассрочку!
A comprehensive guide to optimizing the lifecycle management of pharmaceutical brands The mounting challenges posed by cost containment policies and the prevalence of generic alternatives make optimizing the lifecycle management (LCM) of brand drugs essential for pharmaceutical companies looking to maximize the value of their products. Demonstrating how different measures can be combined to create winning strategies, Pharmaceutical Lifecycle Management: Making the Most of Each and Every Brand explores this increasingly important field to help readers understand what they can—and must—do to get the most out of their brands. Offering a truly immersive introduction to LCM options for pharmaceuticals, the book incorporates numerous real-life case studies that demonstrate successful and failed lifecycle management initiatives, explaining the key takeaway of each example. Filled with practical information on the process of actually writing and presenting an LCM plan, as well as how to link corporate, portfolio, and individual brand strategies, the book also offers a look ahead to predict which LCM strategies will continue to be effective in the future. While the development of new drugs designed to address unmet patient needs remains the single most important goal of any pharmaceutical company, effective LCM is invaluable for getting the greatest possible value from existing brands. Pharmaceutical Lifecycle Management walks you through the process step by step, making it indispensable reading for pharmaceutical executives and managers, as well as anyone working in the fields of drug research, development, and regulation.
Qiang Li Space Electronic Reconnaissance. Localization Theories and Methods Qiang Li Space Electronic Reconnaissance. Localization Theories and Methods Новинка

Qiang Li Space Electronic Reconnaissance. Localization Theories and Methods

11777.18 руб. или Купить в рассрочку!
Presents the theories and applications of determining the position of an object in space through the use of satellites As the importance of space reconnaissance technology intensifies, more and more countries are investing money in building their own space reconnaissance satellites. Due to the secrecy and sensitivity of the operations, it is hard to find published papers and journals on the topic outside of military and governmental agencies. This book aims to fill the gap by presenting the various applications and basic principles of a very modern technology. The space electronic reconnaissance system in mono/multi-satellite platforms is a critical feature which can be used for detection, localization, tracking or identification of the various kinds of signal sources from radar, communication or navigation systems. Localization technology in space electronic reconnaissance uses single or multiple satellite receivers which receive signals from radar, communication and navigation emitters in the ground, ocean and space to specify the location of emitter. The methods, principles and technologies of different space electronic reconnaissance localization systems are introduced in this book, as are their performances, and the various methods are explained and analysed. Digital simulations illustrate the results. Presents the theories and applications of determining the position of an object in space through the use of satellites Introduces methods, principles and technologies of localization and tracking in the space electronic reconnaissance system, the localization algorithm and error in satellite system and near space platform system, and the tracking algorithm and error in single satellite-to-satellite tracking system Provides the fundamentals, the mathematics, the limitations, the measurements, and systems, of localization with emphasis on defence industry applications Highly relevant for Engineers working in avionics, radar, communication, navigation and electronic warfare. Chapters include:– the introduction of space electronic reconnaissance localization technology, knowledge about the satellite orbit and basic terminology of passive localization, single satellite geolocation technology based on direction finding, three-satellite geolocation technology based on time difference of arrival (TDOA), two-satellite geolocation technology based on TDOA and frequency difference of arrival (FDOA), the single satellite localization technology based on kinematics theory, localization principles of near-space platform electronic reconnaissance systems, the orbit determination of single satellite-to-satellite tracking using bearings only(BO) information, the orbit determination of single satellite-to-satellite tracking using bearings and frequency information, the orbit determination of single satellite-to-satellite tracking using frequency only(FO) information. Each chapter ends with a problem and solution section, some using Matlab code.
Clemens Lamberth Bioactive Carboxylic Compound Classes. Pharmaceuticals and Agrochemicals Clemens Lamberth Bioactive Carboxylic Compound Classes. Pharmaceuticals and Agrochemicals Новинка

Clemens Lamberth Bioactive Carboxylic Compound Classes. Pharmaceuticals and Agrochemicals

16341.1 руб. или Купить в рассрочку!
Following the successful and proven concept used in «Bioactive Heterocyclic Compound Classes» by the same editors, this book is the first to present approved pharmaceutical and agrochemical compounds classified by their carboxylic acid functionality in one handy volume. Each of the around 40 chapters describes one or two typical syntheses of a specific compound class and provides concise information on the history of development, mode of action, biological activity and field of application, as well as structure-activity relationships. In addition, similarities and differences between pharmaceuticals and agrochemicals are discussed in the introduction. Written by a team of experts in the field, this is a useful reference for researchers in academia and chemical or pharmaceutical companies working in the field of total synthesis and natural product chemistry, drug development, and crop protection research.
David J. am Ende Chemical Engineering in the Pharmaceutical Industry. R&D to Manufacturing David J. am Ende Chemical Engineering in the Pharmaceutical Industry. R&D to Manufacturing Новинка

David J. am Ende Chemical Engineering in the Pharmaceutical Industry. R&D to Manufacturing

17770.02 руб. или Купить в рассрочку!
This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences. Many of the experimental methods related to pharmaceutical process development are learned on the job. This book is intended to provide many of those important concepts that R&D Engineers and manufacturing Engineers should know and be familiar if they are going to be successful in the Pharmaceutical Industry. These include basic analytics for quantitation of reaction components– often skipped in ChE Reaction Engineering and kinetics books. In addition Chemical Engineering in the Pharmaceutical Industry introduces contemporary methods of data analysis for kinetic modeling and extends these concepts into Quality by Design strategies for regulatory filings. For the current professionals, in-silico process modeling tools that streamline experimental screening approaches is also new and presented here. Continuous flow processing, although mainstream for ChE, is unique in this context given the range of scales and the complex economics associated with transforming existing batch-plant capacity. The book will be split into four distinct yet related parts. These parts will address the fundamentals of analytical techniques for engineers, thermodynamic modeling, and finally provides an appendix with common engineering tools and examples of their applications.
Christine Seymour Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture Christine Seymour Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture Новинка

Christine Seymour Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture

13300.89 руб. или Купить в рассрочку!
Covers a widespread view of Quality by Design (QbD) encompassing the many stages involved in the development of a new drug product. The book provides a broad view of Quality by Design (QbD) and shows how QbD concepts and analysis facilitate the development and manufacture of high quality products. QbD is seen as a framework for building process understanding, for implementing robust and effective manufacturing processes and provides the underpinnings for a science-based regulation of the pharmaceutical industry. Edited by the three renowned researchers in the field, Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture guides pharmaceutical engineers and scientists involved in product and process development, as well as teachers, on how to utilize QbD practices and applications effectively while complying with government regulations. The material is divided into three main sections: the first six chapters address the role of key technologies, including process modeling, process analytical technology, automated process control and statistical methodology in supporting QbD and establishing the associated design space. The second section consisting of seven chapters present a range of thoroughly developed case studies in which the tools and methodologies discussed in the first section are used to support specific drug substance and drug-product QbD related developments. The last section discussed the needs for integrated tools and reviews the status of information technology tools available for systematic data and knowledge management to support QbD and related activities. Highlights Demonstrates Quality by Design (QbD) concepts through concrete detailed industrial case studies involving of the use of best practices and assessment of regulatory implications Chapters are devoted to applications of QbD methodology in three main processing sectors—drug substance process development, oral drug product manufacture, parenteral product processing, and solid-liquid processing Reviews the spectrum of process model types and their relevance, the range of state-of-the-art real-time monitoring tools and chemometrics, and alternative automatic process control strategies and methods for both batch and continuous processes The role of the design space is demonstrated through specific examples and the importance of understanding the risk management aspects of design space definition is highlighted Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture is an ideal book for practitioners, researchers, and graduate students involved in the development, research, or studying of a new drug and its associated manufacturing process.
Otilia M. Y. Koo Pharmaceutical Excipients. Properties, Functionality, and Applications in Research and Industry Otilia M. Y. Koo Pharmaceutical Excipients. Properties, Functionality, and Applications in Research and Industry Новинка

Otilia M. Y. Koo Pharmaceutical Excipients. Properties, Functionality, and Applications in Research and Industry

13300.89 руб. или Купить в рассрочку!
This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical products formulation. It includes development, characterization methodology, applications, and up-to-date advances through the perspectives of excipients developers, users, and regulatory experts. Covers the sources, characterization, and harmonization of excipients: essential information for optimal excipients selection in pharmaceutical development Describes the physico-chemical properties and biological effects of excipients Discusses chemical classes, safety and toxicity, and formulation Addresses recent efforts in the standardization and harmonization of excipients
Hsien-Hsin Tung Crystallization of Organic Compounds. An Industrial Perspective Hsien-Hsin Tung Crystallization of Organic Compounds. An Industrial Perspective Новинка

Hsien-Hsin Tung Crystallization of Organic Compounds. An Industrial Perspective

9729.23 руб. или Купить в рассрочку!
Filled with industrial examples emphasizing the practical applications of crystallization methodologies Based on the authors' hands-on experiences as process engineers at Merck, Crystallization of Organic Compounds guides readers through the practical aspects of crystallization. It uses plenty of case studies and examples of crystallization processes, ranging from development through manufacturing scale-up. The book not only emphasizes strategies that have been proven successful, it also helps readers avoid common pitfalls that can render standard procedures unsuccessful. The goal of this text is twofold: Build a deeper understanding of the fundamental properties of crystallization as well as the impact of these properties on crystallization process development. Improve readers' problem-solving abilities by using actual industrial examples with real process constraints. Crystallization of Organic Compounds begins with detailed discussions of fundamental thermodynamic properties, nucleation and crystal growth kinetics, process dynamics, and scale-up considerations. Next, it investigates modes of operation, including cooling, evaporation, anti-solvent, and reactive crystallization. The authors conclude with special applications such as ultrasound in crystallization and computational fluid dynamics in crystallization. Most chapters feature multiple examples that guide readers step by step through the crystallization of active pharmaceutical ingredients (APIs). With its focus on industrial applications, this book is recommended for chemical engineers and chemists who are involved with the development, scale-up, or operation of crystallization processes in the pharmaceutical and fine chemical industries.
Mike Davis How to Teach Using Simulation in Healthcare Mike Davis How to Teach Using Simulation in Healthcare Новинка

Mike Davis How to Teach Using Simulation in Healthcare

How to Teach Using Simulation in Healthcare provides an ideal introduction and easy-to-use guide to simulation in medical education. Written by a team of experienced medical educators, this practical text – packed full of case examples and tips – is underpinned by the theory of simulation in education, and explores how to integrate simulation into teaching. Key topics include: Use of low, medium and high fidelity equipment Issues of simulation mapping and scenario design Role of human factors Formative and summative assessment New social media and technologies Detailed explorations of some examples of simulation. How to Teach Using Simulation in Healthcare is invaluable reading for all healthcare professionals interested and involved in the origins, theoretical underpinnings, and design implications of the use of simulation in medical education.
Nicolas Abatzoglou Pharmaceutical Blending and Mixing Nicolas Abatzoglou Pharmaceutical Blending and Mixing Новинка

Nicolas Abatzoglou Pharmaceutical Blending and Mixing

12460.8 руб. или Купить в рассрочку!
Written in four parts, this book provides a dedicated and in-depth reference for blending within the pharmaceutical manufacturing industry. It links the science of blending with regulatory requirements associated with pharmaceutical manufacture. The contributors are a combination of leading academic and industrial experts, who provide an informed and industrially relevant perspective of the topic. This is an essential book for the pharmaceutical manufacturing industry, and related academic researchers in pharmaceutical science and chemical and mechanical engineering.
John LaMattina L. Devalued and Distrusted. Can the Pharmaceutical Industry Restore its Broken Image? John LaMattina L. Devalued and Distrusted. Can the Pharmaceutical Industry Restore its Broken Image? Новинка

John LaMattina L. Devalued and Distrusted. Can the Pharmaceutical Industry Restore its Broken Image?

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An expert's view on solving the challenges confronting today's pharmaceutical industry Author John LaMattina, a thirty-year veteran of the pharmaceutical industry and former president of Pfizer's Global R&D Division, is internationally recognized as an expert on the pharmaceutical industry. His first book, Drug Truths: Dispelling the Myths About Pharma R&D, was critically acclaimed for clearing up misconceptions about the pharmaceutical industry and providing an honest account of the contributions of pharmaceutical research and development to human health and well-being. As he toured the country discussing Drug Truths, Dr. LaMattina regularly came across people who were filled with anger, accusing the pharmaceutical industry of making up diseases, hiding dangerous side effects, and more. This book was written in response to that experience, critically examining public perceptions and industry realities. Starting with «4 Secrets that Drug Companies Don't Want You to Know,» Devalued and Distrusted provides a fact-based account of how the pharmaceutical industry works and the challenges it faces. It addresses such critical issues as: Why pharmaceutical R&D productivity has declined Where pharmaceutical companies need to invest their resources What can be done to solve core health challenges, including cancer, diabetes, and neurodegenerative diseases How the pharmaceutical industry can regain public trust and resuscitate its image Our understanding of human health and disease grows daily; however, converting science into medicine is increasingly challenging. Reading Devalued and Distrusted, you'll not only gain a greater appreciation of those challenges, but also the role that the pharmaceutical industry currently plays and can play in solving those challenges. Get to know the author: Read an interview with John LaMattina or watch a video on ChemistryViews! Interview: John LaMattina: 30 Years in Pharma Video: Can the Pharmaceutical Industry Restory its Broken Image?
Andreas Seidel-Morgenstern Preparative Chromatography Andreas Seidel-Morgenstern Preparative Chromatography Новинка

Andreas Seidel-Morgenstern Preparative Chromatography

14973.15 руб. или Купить в рассрочку!
Completely revised and substantially extended to reflect the developments in this fast-changing field. It retains the interdisciplinary approach that elegantly combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. It also covers recent advances in preparative chromatographic processes for the separation of «smaller» molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. The increase in biopharmaceutical substances is reflected by new and revised chapters on different modifications of continuous chromatography as well as ion-exchange chromatography and other separation principles widely used in biochromatography. Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on stationary phases, selection of chromatographic systems and process concepts. A completely new chapter deals with engineering and operation of chromatographic equipment. Final chapters on modeling and determination of model parameters as well as model based design, optimization and control of preparative chromatographic processes allow for optimal selection of chromatographic processes. Essential for chemists and chemical engineers in the chemical, pharmaceutical, and food industries.
Marc Descamps Disordered Pharmaceutical Materials Marc Descamps Disordered Pharmaceutical Materials Новинка

Marc Descamps Disordered Pharmaceutical Materials

14441.69 руб. или Купить в рассрочку!
A one-stop resource for researchers, developers, and post graduate students in pharmaceutical science. This handbook and ready reference provides detailed, but not overloaded information – presenting the topic without unnecessarily complex formalism. As such, it gives a systematic and coherent overview of disordered materials for pharmaceutical applications, covering fundamental aspects, as well as preparation and characterization techniques for the target-oriented development of drug delivery systems based on disordered crystals and amorphous solids. Special attention is paid to examine the different facets and levels of disorder in their structural and dynamic aspects as well as the effect of disorder on dissolution and stability. Chapters on processing induced disorder and on patenting issues round off the book. As a result the book helps overcoming the challenges of using these materials in the pharmaceutical industry. For pharmaceutical and medicinal chemists, materials scientists, clinical physicists, and pharmaceutical laboratories looking to make better and more potent pharmaceuticals.
Rolf Hilfiker Polymorphism in the Pharmaceutical Industry. Solid Form and Drug Development Rolf Hilfiker Polymorphism in the Pharmaceutical Industry. Solid Form and Drug Development Новинка

Rolf Hilfiker Polymorphism in the Pharmaceutical Industry. Solid Form and Drug Development

18161.98 руб. или Купить в рассрочку!
Polymorphism in the Pharmaceutical Industry – Solid Form and Drug Development highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It covers all important issues by way of case studies, ranging from properties and crystallization, via thermodynamics, analytics and theoretical modelling right up to patent issues. As such, the book underscores the importance of solid-state chemistry within chemical and pharmaceutical development. It emphasizes why solid-state issues are important, the approaches needed to avoid problems and the opportunities offered by solid-state properties. The authors include true polymorphs as well as solvates and hydrates, while providing information on physicochemical properties, crystallization thermodynamics, quantum-mechanical modelling, and up-scaling. Important analytical tools to characterize solid-state forms and to quantify mixtures are summarized, and case studies on solid-state development processes in industry are also provided. Written by acknowledged experts in the field, this is a high-quality reference for researchers, project managers and quality assurance managers in pharmaceutical, agrochemical and fine chemical companies as well as for academics and newcomers to organic solid-state chemistry.
Stavros Kromidas The HPLC Expert. Possibilities and Limitations of Modern High Performance Liquid Chromatography Stavros Kromidas The HPLC Expert. Possibilities and Limitations of Modern High Performance Liquid Chromatography Новинка

Stavros Kromidas The HPLC Expert. Possibilities and Limitations of Modern High Performance Liquid Chromatography

10261.41 руб. или Купить в рассрочку!
The rapid development of HPLC instrumentation and technology opens numerous possibilities – and entails new questions. Which column should I choose to obtain best results, which gradient fits to my analytical problem, what are recent and promising trends in detection techniques, what is state of the art regarding LC-MS coupling? All these questions are answered by experts in ten self-contained chapters. Besides these more hardware-related and technical chapters, further related areas of interest are covered: Comparison of recent chromatographic data systems and integration strategies, smart documentation, efficient information search in internet, and tips for a successful FDA inspection. This practical approach offers in a condensed manner recent trends and hints, and will also display the advanced reader mistakes and errors he was not aware of so far.
D. Salmon Michael Practical Pharmacology for the Pharmaceutical Sciences D. Salmon Michael Practical Pharmacology for the Pharmaceutical Sciences Новинка

D. Salmon Michael Practical Pharmacology for the Pharmaceutical Sciences

4560.31 руб. или Купить в рассрочку!
Practical Pharmacology for the Pharmaceutical Sciences is a lab survival guide for those studying Pharmacology, providing hands-on advice on developing pharmacology laboratory and data handling skills. Suitable for both undergraduates and postgraduates, it focuses on laboratory techniques rather than computer-simulated data. It also guides the reader through the process of communicating experimental results in a variety of formats, including posters, oral presentations and project reports. Split into three main areas, the following topics are covered in detail: Preparation for Experimental Pharmacology Legal aspects Fundamentals of Pharmacology Definitions, calculations and statistics Experiments in Pharmacology Microtitre-based techniques using isolated cells In vitro techniques using isolated tissues and organs Biochemical techniques using cell-free systems Communicating experimental results Data presentation How to write scientific reports Pharmacological literature Supported with numerous questions throughout the text, as well as step by step instructions for practical experiments, this book presents an approach to learning pharmacology through an appreciation of authentic experimental data.
Takayuki Shioiri Pharmaceutical Process Chemistry Takayuki Shioiri Pharmaceutical Process Chemistry Новинка

Takayuki Shioiri Pharmaceutical Process Chemistry

17405.46 руб. или Купить в рассрочку!
Covering the whole area of process chemistry in the pharmaceutical industry, this monograph provides the essential knowledge on the basic chemistry needed for future development and key industrial techniques, as well as morphology, engineering and regulatory compliances. Application-oriented and well structured, the authors include recent examples of excellent industrial production of active pharmaceutical ingredients.
Q. Xu Alan Ultra-High Performance Liquid Chromatography and Its Applications Q. Xu Alan Ultra-High Performance Liquid Chromatography and Its Applications Новинка

Q. Xu Alan Ultra-High Performance Liquid Chromatography and Its Applications

Explores both the benefits and limitations of new UHPLC technology High performance liquid chromatography (HPLC) has been widely used in analytical chemistry and biochemistry to separate, identify, and quantify compounds for decades. The science of liquid chromatography, however, was revolutionized a few years ago with the advent of ultra-high performance liquid chromatography (UHPLC), which made it possible for researchers to analyze sample compounds with greater speed, resolution, and sensitivity. Ultra-High Performance Liquid Chromatography and Its Applications enables readers to maximize the performance of UHPLC as well as develop UHPLC methods tailored to their particular research needs. Readers familiar with HPLC methods will learn how to transfer these methods to a UHPLC platform and vice versa. In addition, the book explores a variety of UHPLC applications designed to support research in such fields as pharmaceuticals, food safety, clinical medicine, and environmental science. The book begins with discussions of UHPLC method development and method transfer between HPLC and UHPLC platforms. It then examines practical aspects of UHPLC. Next, the book covers: Coupling UHPLC with mass spectrometry Potential of shell particles in fast liquid chromatography Determination of abused drugs in human biological matrices Analyses of isoflavones and flavonoids Therapeutic protein characterization Analysis of illicit drugs The final chapter of the book explores the use of UHPLC in drug metabolism and pharmacokinetics studies for traditional Chinese medicine. With its frank discussions of UHPLC's benefits and limitations, Ultra-High Performance Liquid Chromatography and Its Applications equips analytical scientists with the skills and knowledge needed to take full advantage of this new separation technology.
Kayser Oliver Pharmaceutical Biotechnology. Drug Discovery and Clinical Applications Kayser Oliver Pharmaceutical Biotechnology. Drug Discovery and Clinical Applications Новинка

Kayser Oliver Pharmaceutical Biotechnology. Drug Discovery and Clinical Applications

30654.15 руб. или Купить в рассрочку!
This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.
Ken Tanaka Rhodium Catalysis in Organic Synthesis. Methods and Reactions Ken Tanaka Rhodium Catalysis in Organic Synthesis. Methods and Reactions Новинка

Ken Tanaka Rhodium Catalysis in Organic Synthesis. Methods and Reactions

21421.82 руб. или Купить в рассрочку!
An essential reference to the highly effective reactions applied to modern organic synthesis Rhodium complexes are one of the most important transition metals for organic synthesis due to their ability to catalyze a variety of useful transformations. Rhodium Catalysis in Organic Synthesis: Methods and Reactions explores the most recent progress and new developments particularly in the field of catalytic cyclization reactions using rhodium(I) complexes and catalytic carbon-hydrogen bond activation reactions using rhodium(II) and rhodium(III) complexes. Edited by a noted expert in the field with contributions from a panel of leading international scientists, Rhodium Catalysis in Organic Synthesis: Methods and Reactions presents the essential information in one comprehensive volume. Designed to be an accessible resource, the book is arranged by different reaction types. All the chapters provide insight into each transformation and include information on the history, selectivity, scope, mechanism, and application. In addition, the chapters offer a summary and outlook of each transformation. This important resource: Offers a comprehensive review of how rhodium complexes catalyze a variety of highly useful reactions for organic synthesis (e.g. coupling reactions, CH-bond functionalization, hydroformylation, cyclization reactions and others) Includes information on the most recent developments that contain a range of new, efficient, elegant, reliable and useful reactions Presents a volume edited by one of the international leading scientists working in the field today Contains the information that can be applied by researchers in academia and also professionals in pharmaceutical, agrochemical and fine chemical companies Written for academics and synthetic chemists working with organometallics, Rhodium Catalysis in Organic Synthesis: Methods and Reactions contains the most recent information available on the developments and applications in the field of catalytic cyclization reactions using rhodium complexes.
Gary Prager Practical Pharmaceutical Engineering Gary Prager Practical Pharmaceutical Engineering Новинка

Gary Prager Practical Pharmaceutical Engineering

13039.37 руб. или Купить в рассрочку!
A practical guide to all key the elements of pharmaceuticals and biotech manufacturing and design Engineers working in the pharmaceutical and biotech industries are routinely called upon to handle operational issues outside of their fields of expertise. Traditionally the competencies required to fulfill those tasks were achieved piecemeal, through years of self-teaching and on-the-job experience—until now. Practical Pharmaceutical Engineering provides readers with the technical information and tools needed to deal with most common engineering issues that can arise in the course of day-to-day operations of pharmaceutical/biotech research and manufacturing. Engineers working in pharma/biotech wear many hats. They are involved in the conception, design, construction, and operation of research facilities and manufacturing plants, as well as the scale-up, manufacturing, packaging, and labeling processes. They have to implement FDA regulations, validation assurance, quality control, and Good Manufacturing Practices (GMP) compliance measures, and to maintain a high level of personal and environmental safety. This book provides readers from a range of engineering specialties with a detailed blueprint and the technical knowledge needed to tackle those critical responsibilities with confidence. At minimum, after reading this book, readers will have the knowledge needed to constructively participate in contractor/user briefings. Provides pharmaceutical industry professionals with an overview of how all the parts fit together and a level of expertise that can take years of on-the-job experience to acquire Addresses topics not covered in university courses but which are crucial to working effectively in the pharma/biotech industry Fills a gap in the literature, providing important information on pharmaceutical operation issues required for meeting regulatory guidelines, plant support design, and project engineering Covers the basics of HVAC systems, water systems, electric systems, reliability, maintainability, and quality assurance, relevant to pharmaceutical engineering Practical Pharmaceutical Engineering is an indispensable “tool of the trade” for chemical engineers, mechanical engineers, and pharmaceutical engineers employed by pharmaceutical and biotech companies, engineering firms, and consulting firms. It also is a must-read for engineering students, pharmacy students, chemistry students, and others considering a career in pharmaceuticals.
Gary Zatzman M. The Greening of Pharmaceutical Engineering, Practice, Analysis, and Methodology Gary Zatzman M. The Greening of Pharmaceutical Engineering, Practice, Analysis, and Methodology Новинка

Gary Zatzman M. The Greening of Pharmaceutical Engineering, Practice, Analysis, and Methodology

17101.87 руб. или Купить в рассрочку!
The pharmaceutical industry is one of the most important industries in the world, offering new medicines, vaccines, and cures to a global population. It is a massive industry, worthy of a deep and thorough examination of its processes and chemistry, with a view toward sustainability. The authors describe what is and isn't truly sustainable, offering a new approach and a new definition of the sustainability of pharmaceutical and chemical engineering and the science behind it. This is a cutting-edge work, aimed at engineers, scientists, researchers, chemists, and students.
Elizabeth Lichtenberger O. Essentials of KTEA-3 and WIAT-III Assessment Elizabeth Lichtenberger O. Essentials of KTEA-3 and WIAT-III Assessment Новинка

Elizabeth Lichtenberger O. Essentials of KTEA-3 and WIAT-III Assessment

4180.28 руб. или Купить в рассрочку!
Written by expert authors Kristina Breaux and Elizabeth Lichtenberger, Essentials of KTEA-3 and WIAT-III Assessment offers up-to-date, comprehensive, step-by-step instruction in the accurate and effective use of the newest editions of the Kaufman Test of Educational Achievement (KTEA-3) Comprehensive Form, KTEA-3 Brief Form, and the Wechsler Individual Achievement Test (WIAT-III). Designed to provide in-depth information in an easy to use reference format, the book provides guidelines and tips for administration, scoring, and interpretation that go beyond the information provided in the test manuals. A complete guide is included for digital administration and scoring using Q-interactive, automated scoring using Q-global, and hand scoring. Essentials of KTEA-3 and WIAT-III Assessment makes score interpretation easier by explaining what each score measures and the implications of a high or low score. Learn how to increase the diagnostic utility of the KTEA-3 and WIAT-III by taking full advantage of their capabilities for error analysis, qualitative observations, and progress monitoring, and by pairing the results with measures of cognitive ability such as the WISC-V and KABC-II. Clinicians will find a helpful discussion of how these tests may be interpreted using either a CHC or neuropsychological approach to assessment. Case studies illustrate the use of these tests to respond to various referral concerns. Annotations within each case report provide a window into the mind of the examiner throughout the assessment process. This book provides a depth and breadth of understanding that is appropriate for all assessment professionals, regardless of their level of training or experience. Extensive illustrations, call-out boxes, and «Test Yourself» questions help students and clinicians quickly absorb the information they need. Essentials of KTEA-3 and WIAT-III Assessment is the clear, focused guide to using these tests to their fullest potential.
Sisu: The Finnish Art of Courage Sisu: The Finnish Art of Courage Новинка

Sisu: The Finnish Art of Courage

A comprehensive guide to the Finnish attitude of courage and determination in the face of adversity.
K. Mittal L. Adhesion in Pharmaceutical, Biomedical, and Dental Fields K. Mittal L. Adhesion in Pharmaceutical, Biomedical, and Dental Fields Новинка

K. Mittal L. Adhesion in Pharmaceutical, Biomedical, and Dental Fields

17101.87 руб. или Купить в рассрочку!
The phenomenon of adhesion is of cardinal importance in the pharmaceutical, biomedical and dental fields. A few eclectic examples will suffice to underscore the importance/relevance of adhesion in these three areas. For example, the adhesion between powdered solids is of crucial importance in tablet manufacture. The interaction between biodevices (e.g., stents, bio-implants) and body environment dictates the performance of such devices, and there is burgeoning research activity in modifying the surfaces of such implements to render them compatible with bodily components. In the field of dentistry, the modern trend is to shift from retaining of restorative materials by mechanical interlocking to adhesive bonding. This unique book addresses all these three areas in an easily accessible single source. The book contains 15 chapters written by leading experts and is divided into four parts: General Topics; Adhesion in Pharmaceutical Field; Adhesion in Biomedical Field; and Adhesion in Dental Field. The topics covered include: – Theories or mechanisms of adhesion. – Wettability of powders. – Role of surface free energy in tablet strength and powder flow behavior. – Mucoadhesive polymers for drug delivery systems. – Transdermal patches. – Skin adhesion in long-wear cosmetics. – Factors affecting microbial adhesion. – Biofouling and ways to mitigate it. – Adhesion of coatings on surgical tools and bio-implants. – Adhesion in fabrication of microarrays in clinical diagnostics. – Antibacterial polymers for dental adhesives and composites. – Evolution of dental adhesives. – Testing of dental adhesives joints.
Roderick Bates Organic Synthesis Using Transition Metals Roderick Bates Organic Synthesis Using Transition Metals Новинка

Roderick Bates Organic Synthesis Using Transition Metals

13194.6 руб. или Купить в рассрочку!
Transition metals open up new opportunities for synthesis, because their means of bonding and their reaction mechanisms differ from those of the elements of the s and p blocks. In the last two decades the subject has mushroomed – established reactions are seeing both technical improvements and increasing numbers of applications, and new reactions are being developed. The practicality of the subject is demonstrated by the large number of publications coming from the process development laboratories of pharmaceutical companies, and its importance is underlined by the fact that three Nobel prizes have been awarded for discoveries in this field in the 21st Century already. Organic Synthesis Using Transition Metals, 2nd Edition considers the ways in which transition metals, as catalysts and reagents, can be used in organic synthesis, both for pharmaceutical compounds and for natural products. It concentrates on the bond-forming reactions that set transition metal chemistry apart from «classical» organic chemistry. Each chapter is extensively referenced and provides a convenient point of entry to the research literature. Topics covered include: introduction to transition metals in organic synthesis coupling reactions C-H activation carbonylative coupling reactions alkene and alkyne insertion reactions electrophilic alkene and alkyne complexes reactions of alkyne complexes carbene complexes h3- or p-allyl -allyl complexes diene, dienyl and arene complexes cycloaddition and cycloisomerisation reactions For this second edition the text has been extensively revised and expanded to reflect the significant improvements and advances in the field since the first edition, as well as the large number of new transition metal-catalysed processes that have come to prominence in the last 10 years – for example the extraordinary progress in coupling reactions using “designer” ligands, catalysis using gold complexes, new opportunities arising from metathesis chemistry, and C-H activation – without neglecting the well established chemistry of metals such as palladium. Organic Synthesis Using Transition Metals, 2nd Edition will find a place on the bookshelves of advanced undergraduates and postgraduates working in organic synthesis, catalysis, medicinal chemistry and drug discovery. It is also useful for practising researchers who want to refresh and enhance their knowledge of the field.
Andreas Liese Biocatalysis for the Pharmaceutical Industry. Discovery, Development, and Manufacturing Andreas Liese Biocatalysis for the Pharmaceutical Industry. Discovery, Development, and Manufacturing Новинка

Andreas Liese Biocatalysis for the Pharmaceutical Industry. Discovery, Development, and Manufacturing

12157.21 руб. или Купить в рассрочку!
Biocatalysis is rapidly evolving into a key technology for the discovery and production of chemicals, especially in the pharmaceutical industry, where high yielding chemo-, regio-, and enantioselective reactions are critical. Taking the latest breakthroughs in genomics and proteomics into consideration, Biocatalysis for the Pharmaceutical Industry concisely yet comprehensively discusses the modern application of biocatalysis to drug discovery, development, and manufacturing. Written by a team of leading experts, the book offers deep insight into this cutting edge field. Covers a wide range of topics in a systematic manner with an emphasis on industrial applications Provides a thorough introduction to the latest biocatalysts, modern expression hosts, state-of-the-art directed evolution, high throughput screening, and bioprocess engineering Addresses frontier subjects such as emerging enzymes, metabolite profiling, combinatorial biosynthesis, metabolic engineering, and autonomous enzymes for the synthesis and development of chiral molecules, drug metabolites, and semi-synthetic medicinal compounds and natural product analogs Highlights the impact of biocatalysis on green chemistry Contains numerous graphics to illustrate concepts and techniques Biocatalysis for the Pharmaceutical Industry is an essential resource for scientists, engineers, and R&D policy makers in the fine chemical, pharmaceutical, and biotech industries. It is also an invaluable tool for academic researchers and advanced students of organic and materials synthesis, chemical biology, and medicinal chemistry.
Yuriy Abramov A. Computational Pharmaceutical Solid State Chemistry Yuriy Abramov A. Computational Pharmaceutical Solid State Chemistry Новинка

Yuriy Abramov A. Computational Pharmaceutical Solid State Chemistry

11397.16 руб. или Купить в рассрочку!
This book is the first to combine computational material science and modeling of molecular solid states for pharmaceutical industry applications. • Provides descriptive and applied state-of-the-art computational approaches and workflows to guide pharmaceutical solid state chemistry experiments and to support/troubleshoot API solid state selection • Includes real industrial case examples related to application of modeling methods in problem solving • Useful as a supplementary reference/text for undergraduate, graduate and postgraduate students in computational chemistry, pharmaceutical and biotech sciences, and materials science
Colin Aitken Statistical Analysis in Forensic Science. Evidential Values of Multivariate Physicochemical Data Colin Aitken Statistical Analysis in Forensic Science. Evidential Values of Multivariate Physicochemical Data Новинка

Colin Aitken Statistical Analysis in Forensic Science. Evidential Values of Multivariate Physicochemical Data

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A practical guide for determining the evidential value of physicochemical data Microtraces of various materials (e.g. glass, paint, fibres, and petroleum products) are routinely subjected to physicochemical examination by forensic experts, whose role is to evaluate such physicochemical data in the context of the prosecution and defence propositions. Such examinations return various kinds of information, including quantitative data. From the forensic point of view, the most suitable way to evaluate evidence is the likelihood ratio. This book provides a collection of recent approaches to the determination of likelihood ratios and describes suitable software, with documentation and examples of their use in practice. The statistical computing and graphics software environment R, pre-computed Bayesian networks using Hugin Researcher and a new package, calcuLatoR, for the computation of likelihood ratios are all explored. Statistical Analysis in Forensic Science will provide an invaluable practical guide for forensic experts and practitioners, forensic statisticians, analytical chemists, and chemometricians. Key features include: Description of the physicochemical analysis of forensic trace evidence. Detailed description of likelihood ratio models for determining the evidential value of multivariate physicochemical data. Detailed description of methods, such as empirical cross-entropy plots, for assessing the performance of likelihood ratio-based methods for evidence evaluation. Routines written using the open-source R software, as well as Hugin Researcher and calcuLatoR. Practical examples and recommendations for the use of all these methods in practice.
Wang Jichuan Structural Equation Modeling. Applications Using Mplus Wang Jichuan Structural Equation Modeling. Applications Using Mplus Новинка

Wang Jichuan Structural Equation Modeling. Applications Using Mplus

9080.99 руб. или Купить в рассрочку!
A reference guide for applications of SEM using Mplus Structural Equation Modeling: Applications Using Mplus is intended as both a teaching resource and a reference guide. Written in non-mathematical terms, this book focuses on the conceptual and practical aspects of Structural Equation Modeling (SEM). Basic concepts and examples of various SEM models are demonstrated along with recently developed advanced methods, such as mixture modeling and model-based power analysis and sample size estimate for SEM. The statistical modeling program, Mplus, is also featured and provides researchers with a flexible tool to analyze their data with an easy-to-use interface and graphical displays of data and analysis results. Key features: Presents a useful reference guide for applications of SEM whilst systematically demonstrating various advanced SEM models, such as multi-group and mixture models using Mplus. Discusses and demonstrates various SEM models using both cross-sectional and longitudinal data with both continuous and categorical outcomes. Provides step-by-step instructions of model specification and estimation, as well as detail interpretation of Mplus results. Explores different methods for sample size estimate and statistical power analysis for SEM. By following the examples provided in this book, readers will be able to build their own SEM models using Mplus. Teachers, graduate students, and researchers in social sciences and health studies will also benefit from this book.
Ramesh Patel N. Green Biocatalysis Ramesh Patel N. Green Biocatalysis Новинка

Ramesh Patel N. Green Biocatalysis

17101.87 руб. или Купить в рассрочку!
Green Biocatalysis presents an exciting green technology that uses mild and safe processes with high regioselectivity and enantioselectivity. Bioprocesses are carried out under ambient temperature and atmospheric pressure in aqueous conditions that do not require any protection and deprotection steps to shorten the synthetic process, offering waste prevention and using renewable resources. Drawing on the knowledge of over 70 internationally renowned experts in the field of biotechnology, Green Biocatalysis discusses a variety of case studies with emphases on process R&D and scale-up of enzymatic processes to catalyze different types of reactions. Random and directed evolution under process conditions to generate novel highly stable and active enzymes is described at length. This book features: A comprehensive review of green bioprocesses and application of enzymes in preparation of key compounds for pharmaceutical, fine chemical, agrochemical, cosmetic, flavor, and fragrance industries using diverse enzymatic reactions Discussion of the development of efficient and stable novel biocatalysts under process conditions by random and directed evolution and their applications for the development of environmentally friendly, efficient, economical, and sustainable green processes to get desired products in high yields and enantiopurity The most recent technological advances in enzymatic and microbial transformations and cuttingedge topics such as directed evolution by gene shuffling and enzyme engineering to improve biocatalysts With over 3000 references and 800 figures, tables, equations, and drawings, Green Biocatalysis is an excellent resource for biochemists, organic chemists, medicinal chemists, chemical engineers, microbiologists, pharmaceutical chemists, and undergraduate and graduate students in the aforementioned disciplines.
Ekins Sean Pharmaceutical Data Mining. Approaches and Applications for Drug Discovery Ekins Sean Pharmaceutical Data Mining. Approaches and Applications for Drug Discovery Новинка

Ekins Sean Pharmaceutical Data Mining. Approaches and Applications for Drug Discovery

12418.44 руб. или Купить в рассрочку!
Leading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, who address both the implementation of new data mining technologies and application issues in the industry. This accessible, comprehensive collection discusses important theoretical and practical aspects of pharmaceutical data mining, focusing on diverse approaches for drug discovery—including chemogenomics, toxicogenomics, and individual drug response prediction. The five main sections of this volume cover: A general overview of the discipline, from its foundations to contemporary industrial applications Chemoinformatics-based applications Bioinformatics-based applications Data mining methods in clinical development Data mining algorithms, technologies, and software tools, with emphasis on advanced algorithms and software that are currently used in the industry or represent promising approaches In one concentrated reference, Pharmaceutical Data Mining reveals the role and possibilities of these sophisticated techniques in contemporary drug discovery and development. It is ideal for graduate-level courses covering pharmaceutical science, computational chemistry, and bioinformatics. In addition, it provides insight to pharmaceutical scientists, principal investigators, principal scientists, research directors, and all scientists working in the field of drug discovery and development and associated industries.
Ken Getz VBA Developer's Handbook Ken Getz VBA Developer's Handbook Новинка

Ken Getz VBA Developer's Handbook

3880.12 руб. или Купить в рассрочку!
WRITE BULLETPROOF VBA CODE FOR ANY SITUATION This book is the essential resource for developers working with any of the more than 300 products that employ the Visual Basic for Applications programming language. Written by recognized VBA experts, it provides detailed coverage of a wide range of specific VBA programming challenges. Its careful, step-by-step instructions and thousands of lines of code offer answers, while teaching you to devise new and creative solutions. The instruction applies equally to all VBA environments, whether you are building standalone applications or customizing commercial products using their built-in VBA programmability. Coverage Includes Manipulating text, numbers, and dates Using automation to control other applications Creating objects using VBA class modules Using standard search and sort algorithms from within VBA Creating standard dynamic data structures, including linked lists, binary trees, stacks, and queues Working with Windows system information, including memory status, screen info, mouse, keyboard, and power status Working with Windows Registry data Retrieving and setting Windows networking information Working with the Windows file system, iterating through folders, creating and deleting files Adding sound and movies to VBA apps using Windows multimedia extensions Tapping the system capabilities provided by the Windows Scripting Runtime library Writing add-ins for the Visual Basic environment Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.
Katja Strohfeldt A. Essentials of Inorganic Chemistry. For Students of Pharmacy, Pharmaceutical Sciences and Medicinal Chemistry Katja Strohfeldt A. Essentials of Inorganic Chemistry. For Students of Pharmacy, Pharmaceutical Sciences and Medicinal Chemistry Новинка

Katja Strohfeldt A. Essentials of Inorganic Chemistry. For Students of Pharmacy, Pharmaceutical Sciences and Medicinal Chemistry

5433.07 руб. или Купить в рассрочку!
A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective. Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health-care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as stand-alone concepts, allowing students to see the relevance of this subject for their future professions. It includes exercises and case studies.
Elizabeth Oldfield Looking After Dad Elizabeth Oldfield Looking After Dad Новинка

Elizabeth Oldfield Looking After Dad

FROM HERE TO PATERNITYSingle dad requires protection! When Lorcan Hunter is threatened by someone opposed to his latest business project, and leggy blonde Jess Pallister presents herself as the person to protect him, Lorcan is more than a little skeptical! But when his little girl is also threatened, Lorcan is forced to trust Jess.Bright and beautiful Jess soon becomes part of the family, and before he knows it, Lorcan is ready to offer her a permanent assignment so she can watch over both of them for life!FROM HERE TO PATERNITY – men who find their way to fatherhood by fair means, by foul, or even by default!
Ernesto Tomei Text-Atlas of Skeletal Age Determination. MRI of the Hand and Wrist in Children Ernesto Tomei Text-Atlas of Skeletal Age Determination. MRI of the Hand and Wrist in Children Новинка

Ernesto Tomei Text-Atlas of Skeletal Age Determination. MRI of the Hand and Wrist in Children

12157.21 руб. или Купить в рассрочку!
The first complete textbook and atlas of the vitally important technique of bone age assessment utilizing MRI for children's hand and wrist This latest volume in the growing Wiley Current Clinical Imaging series is a must-have resource that collects, in a single volume, all that is currently known and applicable about the use of magnetic resonance imaging (MRI) for the assessment of bone age. Presented in two parts, Text-Atlas of Skeletal Age Determination: MRI of the Hand and Wrist in Children first focuses on the anatomic, social, and legal aspects of bone age, providing a concise overview of the use of bone age determination in medical, legal, and social systems.??It then covers the clinical use and application of MRI in assessing bone age. The book offers complete chapter coverage on endocrinology, puberty, and disorders of pubertal development; bone marrow maturation in healthy and diseased states; growth failure and pediatric inflammatory bowel disease; skeletal findings in neurometabolic disease, genetic disease, and pediatric oncology patients; and much more. Text-Atlas of Skeletal Age Determination provides: A comprehensive review of the medical, legal, and social aspects of bone age assessment An in-depth discussion of MRI as an alternative to the traditional ionizing radiation-based radiographic techniques for the assessment of bone age Complete guidelines for clinical application of these MRI-based techniques «Recipes» for replicating these techniques and applications for diverse patient populations Cutting-edge information prepared and presented by an international team of experts A superb collection of beautifully reproduced, high-quality images This is an ideal book for radiologists, pediatricians, family physicians, endocrinologists, and sports medicine physicians interested in skeletal development and bone age assessment.
Alessandra Mattei Pharmaceutical Crystals. Science and Engineering Alessandra Mattei Pharmaceutical Crystals. Science and Engineering Новинка

Alessandra Mattei Pharmaceutical Crystals. Science and Engineering

14552.87 руб. или Купить в рассрочку!
An important resource that puts the focus on understanding and handling of organic crystals in drug development Since a majority of pharmaceutical solid-state materials are organic crystals, their handling and processing are critical aspects of drug development. Pharmaceutical Crystals: Science and Engineering offers an introduction to and thorough coverage of organic crystals, and explores the essential role they play in drug development and manufacturing. Written contributions from leading researchers and practitioners in the field, this vital resource provides the fundamental knowledge and explains the connection between pharmaceutically relevant properties and the structure of a crystal. Comprehensive in scope, the text covers a range of topics including: crystallization, molecular interactions, polymorphism, analytical methods, processing, and chemical stability. The authors clearly show how to find solutions for pharmaceutical form selection and crystallization processes. Designed to be an accessible guide, this book represents a valuable resource for improving the drug development process of small drug molecules. This important text: Includes the most important aspects of solid-state organic chemistry and its role in drug development Offers solutions for pharmaceutical form selection and crystallization processes Contains a balance between the scientific fundamental and pharmaceutical applications Presents coverage of crystallography, molecular interactions, polymorphism, analytical methods, processing, and chemical stability Written for both practicing pharmaceutical scientists, engineers, and senior undergraduate and graduate students studying pharmaceutical solid-state materials, Pharmaceutical Crystals: Science and Engineering is a reference and textbook for understanding, producing, analyzing, and designing organic crystals which is an imperative skill to master for anyone working in the field.
Salah Khalfallah Structural Analysis 1. Statically Determinate Structures Salah Khalfallah Structural Analysis 1. Statically Determinate Structures Новинка

Salah Khalfallah Structural Analysis 1. Statically Determinate Structures

10672.1 руб. или Купить в рассрочку!
Using a general approach, this book supports the student to enable mastery of the methods of analysis of isostatic and hyperstatic structures. To show the performance of the methods of analysis of the hyperstatic structures, selected beams, gantries and reticular structures are selected and subjected to a comparative study by the different methods of analysis of the hyperstatic structures.

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Presents the theories and applications of determining the position of an object in space through the use of satellites As the importance of space reconnaissance technology intensifies, more and more countries are investing money in building their own space reconnaissance satellites. Due to the secrecy and sensitivity of the operations, it is hard to find published papers and journals on the topic outside of military and governmental agencies. This book aims to fill the gap by presenting the various applications and basic principles of a very modern technology. The space electronic reconnaissance system in mono/multi-satellite platforms is a critical feature which can be used for detection, localization, tracking or identification of the various kinds of signal sources from radar, communication or navigation systems. Localization technology in space electronic reconnaissance uses single or multiple satellite receivers which receive signals from radar, communication and navigation emitters in the ground, ocean and space to specify the location of emitter. The methods, principles and technologies of different space electronic reconnaissance localization systems are introduced in this book, as are their performances, and the various methods are explained and analysed. Digital simulations illustrate the results. Presents the theories and applications of determining the position of an object in space through the use of satellites Introduces methods, principles and technologies of localization and tracking in the space electronic reconnaissance system, the localization algorithm and error in satellite system and near space platform system, and the tracking algorithm and error in single satellite-to-satellite tracking system Provides the fundamentals, the mathematics, the limitations, the measurements, and systems, of localization with emphasis on defence industry applications Highly relevant for Engineers working in avionics, radar, communication, navigation and electronic warfare. Chapters include:– the introduction of space electronic reconnaissance localization technology, knowledge about the satellite orbit and basic terminology of passive localization, single satellite geolocation technology based on direction finding, three-satellite geolocation technology based on time difference of arrival (TDOA), two-satellite geolocation technology based on TDOA and frequency difference of arrival (FDOA), the single satellite localization technology based on kinematics theory, localization principles of near-space platform electronic reconnaissance systems, the orbit determination of single satellite-to-satellite tracking using bearings only(BO) information, the orbit determination of single satellite-to-satellite tracking using bearings and frequency information, the orbit determination of single satellite-to-satellite tracking using frequency only(FO) information. Each chapter ends with a problem and solution section, some using Matlab code.
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