research in sudanese hiv patients

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Ian Williams ABC of HIV and AIDS Ian Williams ABC of HIV and AIDS
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Ian Williams ABC of HIV and AIDS


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4046.1 руб.

An authoritative guide to the epidemiology, incidence, testing and diagnosis and management of HIV and AIDS. From an international expert editor and contributor team, this new sixth edition includes expanded coverage of HIV testing, assessment and routine follow up and new chapters outlining problematic conditions associated with HIV and AIDS. Prevention strategies, early diagnosis and antiretroviral drugs and pharmacotherapy are covered in detail as well as children and women with HIV. It also addresses key psychological and mental health issues, patient perspectives and the role of patient engagement. As knowledge into the illness grows and major advances in HIV therapy see more people living with HIV in the community, the ABC of HIV and AIDS, 6e provides clear practical guidance for general practitioners, hospital doctors, nurses, medical students, counsellors, allied health workers and anyone working and caring for patients with HIV and AIDS.

Peter Selwyn A. Chronic Pain and HIV. A Practical Approach Peter Selwyn A. Chronic Pain and HIV. A Practical Approach
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Peter Selwyn A. Chronic Pain and HIV. A Practical Approach


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7683.81 руб.

Patients suffering from HIV/AIDS often experience chronic pain due to the many diseases and infections they pick up as a result of a weakened immune system. It interferes with their quality of life and physical functioning, impacts adherence to antiretroviral therapy and HIV primary care, and is associated with significant psychological/social distress and substance use disorders. Chronic Pain and HIV addresses all these complex issues that can influence pain care that can influence pain care for the patient with HIV and acts both as a primer and a comprehensive review to define the field of chronic pain management. Using a clear, clinical approach, key topics include the following: Musculoskeletal pain in individuals in HIV Headache in individuals with HIV Psychiatric comorbidities among individuals with HIV and chronic pain Potential benefit and harm of prescription opioids in HIV Pain at the end of life in individuals with AIDS Treatment of chronic pain syndromes in the HIV-infected person. Edited by an outstanding team with extensive experience in HIV/AIDS and pain/palliative care, every chapter is written by a world-famous expert in their field who provides a thorough review of the relevant literature, including the very latest in management guidelines from the leading international societies. Perfect for all those in primary care, as well as infectious disease specialists managing patients with HIV/AIDS, Chronic Pain and HIV provides sensible, straightforward clinical advice to ensure the best possible patient management.

The Johns Hopkins Hospital 1998-1999 Guide to Medical Care of Patients With HIV Infection The Johns Hopkins Hospital 1998-1999 Guide to Medical Care of Patients With HIV Infection
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The Johns Hopkins Hospital 1998-1999 Guide to Medical Care of Patients With HIV Infection


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129 руб.

Издание на английском языке. The Johns Hopkins Hospital 1998-1999 Guide to Medical Care of Patients With HIV Infection. / Руководство по уходу за пациентами с диагнозом ВИЧ инфекция. Госпиталь имени Джона Хопкинса 1998-1999 гг. This pocket guide provides guidelines for the care of HIV patients. Recommendations reflect the work of the AIDS care programme at Johns Hopkins. / Карманное руководство по уходу за ВИЧ-инфицированными пациентами. Рекомендации отражают работу по программе лечения СПИДа в Госпитале имени Джона Хопкинса

Igor Grant HIV and Psychiatry Igor Grant HIV and Psychiatry
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Igor Grant HIV and Psychiatry


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7569.98 руб.

Mental health and HIV/AIDS are closely interlinked. Mental disorders, including substance-use disorders, are associated with increased risk of HIV infection and affect adherence to and efficacy of antiretroviral treatments. Conversely, HIV infection can increase risk for neuropsychiatric complications including stress, mood, and neurocognitive disorders. This book provides clinicians with a comprehensive evidenced-based and practical approach to the management of patients with HIV infection and co-morbid mental disorders. It provides up-to-date and clear overviews of current clinical issues, as well as the relevant basic science. Information and data from studies of different HIV groups (eg men who have sex with men) make the text relevant to a broad spectrum of clinicians, including those working with low socioeconomic status groups in high income countries and those working in the developing world. The book uses the popular format of the World Psychiatric Association’s Evidence and Experience series. Review chapters summarize the evidence on the epidemiology, pathogenesis and clinical aspects of mental disorders in HIV,and interventions (both psychotherapy and psychopharmacology including drug-drug interactions). These are complemented by commentaries addressing particular facets of each topic and providing insight gained from clinical experience. Psychiatrists, psychologists and all mental health staff working with HIV-infected patients will find this book of great benefit.

Cynthia Poindexter Cannon Handbook of HIV and Social Work. Principles, Practice, and Populations Cynthia Poindexter Cannon Handbook of HIV and Social Work. Principles, Practice, and Populations
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Cynthia Poindexter Cannon Handbook of HIV and Social Work. Principles, Practice, and Populations


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4278.51 руб.

Praise for Handbook of HIV and Social Work «Cynthia Cannon Poindexter has given us a remarkable edited volume that contains much information on HIV that every professional social worker needs to know in order to practice competently in today's complex world.»—From the Foreword by Vincent J. Lynch, MSW, PhD, Boston College Graduate School of Social Work «This comprehensive handbook assembles a group of social work scholars and practitioners to participate in, guide, and address many of the unresolved challenges characterizing the HIV debates. This handbook is a valuable and timely addition to the literature.»—King Davis, MSW, PhD, The Robert Lee Sutherland Chair in Mental Health and Social Policy, The University of Texas at Austin School of Social Work «This handbook is an outstanding resource for the social work professional working to ensure equal access to care, treatment, and resources for all persons living with and/or affected by HIV.»—Evelyn P. Tomaszewski, MSW, Project Director, NASW HIV/AIDS Spectrum: Mental Health Training and Education of Social Workers Project «This book is an excellent, up-to-date guide on HIV. It is an indispensable resource for all those who work with HIV and all its complications.»—Leon Ginsberg, MSW, PhD, Dean Emeritus, University of South Carolina School of Social Work and Editor, Administration in Social Work The most current knowledge on the HIV pandemic in a thorough, diverse, and accessible volume This invaluable book draws on a distinguished roster of HIV advocates, educators, case managers, counselors, and administrators, assembling the most current knowledge into this volume. Handbook of HIV and Social Work reflects the latest research and its impact on policy and practice realities, with topics including: History, Illness, Transmission, and Treatment Social Work Roles, Tasks, and Challenges in Health Care Settings HIV-related Community Organizing and Grassroots Advocacy The Impact of HIV on Children and Adolescents HIV-affected Caregivers

Nicholas Katsilambros Clinical Nutrition in Practice Nicholas Katsilambros Clinical Nutrition in Practice
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Nicholas Katsilambros Clinical Nutrition in Practice


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6373.29 руб.

An easy-to-use book with questions on clinical nutrition clearly posed and answers based on real-life studies, this is a ready reference for the busy healthcare professional. Clinical Nutrition in Practice opens with introductory chapters on the basis of healthy nutrition, malnutrition and nutritional assessment. These are followed by chapters addressing the nutritional needs of patients with obesity, diabetes, cardiovascular disease, rheumatoid and neurologic disorders, as well as diseases of various organ systems, such as the GI tract, renal and pulmonary systems. Special attention is given to describing nutrition in cancer patients and those with HIV/AIDS and the book concludes with a discussion of enteral and parenteral nutrition. Nutritionists, dietitians and other health professionals working with patients with impaired nutrition or special nutritional requirements, such as diabetologists, endocrinologists (especially those treating obesity), cardiologists and oncologists will find this a refreshing approach to an important subject. Nurses, medical students and those working in the food industry will also find this a handy guide. Easy-to-follow style with questions clearly posed and answers based on real-life case studies Outlines the basics of healthy nutrition, malnutrition and nutritional assessment Detailed consideration of the nutritional needs of patients with a variety of chronic diseases, e.g. cardiovascular or rheumatoid disorders, cancer and HIV/AIDS Uses an interesting contemporary approach that health professionals will find a refreshing change

Elizabeth Morrow Handbook of User Involvement in Nursing and Healthcare Research Elizabeth Morrow Handbook of User Involvement in Nursing and Healthcare Research
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Elizabeth Morrow Handbook of User Involvement in Nursing and Healthcare Research


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4123.65 руб.

This book fills an important niche in the market providing practical expert advice on the involvement of service users – patients, carers and the public – in nursing and healthcare research. An invaluable guide for anyone working or involved in nursing and healthcare research, this book provides a step-by-step guide to the principles and process of involvement, including understanding the rationale for involvement, designing involvement, working with service users, and evaluating what has been achieved. With illustrations, worked examples and tool sheets throughout, this evidence-based guide uses real life examples from recent research studies in health and social care research, thus relating theory to practice in a meaningful way. The Handbook of Service User Involvement in Nursing & Healthcare Research introduces a wide range of key issues, including: Why? Why should researchers involve service users? How? How can researchers and service users work together successfully and productively? Who? Who chooses to become involved in research? How are issues of representation and diversity addressed? When? At what stage should service users be involved in the research process?

Vivian Pribram Nutrition and HIV Vivian Pribram Nutrition and HIV
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Vivian Pribram Nutrition and HIV


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6300.43 руб.

Today over 40 million adults and children worldwide are infected with HIV, however knowledge of the disease has increased greatly and the prognosis is now good for those with access to anti-retroviral treatment. For many, HIV is now a long-term chronic condition and with decreased mortality, patient requirements and disease patterns have changed, making it increasingly apparent to health care professionals that the treatment of HIV should include optimum nutrition and healthy lifestyle interventions to help sufferers lead long and healthy lives. In this essential new book an international team of authors under the editorship of Specialist HIV Dietitian Vivian Pribram bring together the latest research to provide the practicing dietitian and nutritionist with a practical guide to the nutritional care of the HIV and AIDS patient. Students and other health care professionals working and studying this area will also find Nutrition and HIV an important and valuable resource.

Brian Burt A. Clinical Research in Oral Health Brian Burt A. Clinical Research in Oral Health
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Brian Burt A. Clinical Research in Oral Health


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7722.94 руб.

Clinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvement.

Mohamad Mohty Clinical Guide to Transplantation in Lymphoma Mohamad Mohty Clinical Guide to Transplantation in Lymphoma
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Mohamad Mohty Clinical Guide to Transplantation in Lymphoma


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11469.51 руб.

The first book on clinical guide to transplantation in lymphoma to present cutting edge knowledge on how to integrate, transplantation and novel therapies in patients with lymphoid malignancies Provides practical management guidance on how to integrate, transplantation and novel therapies in patients with lymphoid malignancies Covers an overview of transplantation in lymphoma, and management of the lymphoid malignancies Discusses organizational aspects of transplant patients and managing a transplant program Appendices provide practical quick-reference information on follow-up after autologous and allogenic stem cell transplantation in lymphoma

Montgomery Stuart A. Treatment-Resistant Depression Montgomery Stuart A. Treatment-Resistant Depression
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Montgomery Stuart A. Treatment-Resistant Depression


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4196.83 руб.

Successful management of patients with treatment-resistant depression is going to require a thorough understanding of the biological basis for both the depression and its failure to respond to standard treatments. This book clearly and succinctly summarizes the latest scientific research and its applications in clinical practice. A first step is a clear definition of what constitutes treatment-resistant depression so that clinical trials and other studies are using common criteria, enabling comparison and meta-analysis of their outcomes. The opening chapter reviews definitions and predictors of originating from different fields and discusses their usefulness in clinical practice and clinical research. The next chapter proposes a new definition, adapting terminology from medicine. Biological classification requires identification of genetic risk factors: with gene variants accounting for 50% of the variance in the clinical outcomes of antidepressant treatments this is clearly a fruitful area of research. Chapter 3 describes several genes already associated with treatment-resistant depression and, while further work is needed to translate findings into clinical recommendations, predicts that genetic prediction of TRD could became a widespread clinical reality within a few years. Most patients with TRD will be treated pharmacologically and three chapters review the latest evidence for pharmacological best practice, including switching strategies for antidepressants, the role of antipsychotics and augmentation strategies to complement lithium. There are two major alternatives to pharmacotherapy: neuromodulation and psychotherapy. The brain intervention chapter summarizes clinical research and experience with electroconvulsive therapy, transcranial magnetic stimulation, vagus nerve stimulation, deep brain stimulation and magnetic seizure therapy. The final chapter reviews the literature pertaining to the effectiveness of various forms of psychotherapy in patients who have not responded to antidepressant pharmacotherapy, revealing that patients who have not responded to one or two trials of antidepressant medication have a 30%-50% chance of responding to a focused psychotherapy. It proposes indications for psychotherapy in TRD and summarizes general therapeutic principles.

Stefan G. Hofmann Psychobiological Approaches for Anxiety Disorders. Treatment Combination Strategies Stefan G. Hofmann Psychobiological Approaches for Anxiety Disorders. Treatment Combination Strategies
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Stefan G. Hofmann Psychobiological Approaches for Anxiety Disorders. Treatment Combination Strategies


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9019.88 руб.

Psychobiological Approaches for Anxiety Disorders presents a comprehensive overview of the latest empirical evidence and research results on combining pharmacological agents and CBT techniques for the treatment of anxiety disorders. The first book to focus on the issue of enhancing CBT with pharmacological agents Features chapters from leading authors in the fields of psychiatry, pharmacology, clinical psychology, neuroscience, and emotion research Contributes significantly to the field by summarizing the contemporary research in combination treatments in anxiety disorders A valuable resource for clinicians in training, as well as experienced clinicians seeking to help patients with anxiety disorders

Zhu Hua Research Methods in Intercultural Communication. A Practical Guide Zhu Hua Research Methods in Intercultural Communication. A Practical Guide
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Zhu Hua Research Methods in Intercultural Communication. A Practical Guide


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3370.92 руб.

Research Methods in Intercultural Communication introduces and contextualizes the most important methodological issues in the field for upper-level undergraduate and graduate students. Examples of these issues are which paradigms and how to research multilingually, interculturally and ethnically. Provides the first dedicated and most comprehensive volume on research methods in intercultural communication research in the last 30 years Explains new and emerging methods, as well as more established ones. These include: Matched Guise Technique, Discourse Completion Task, Critical Incident Technique, Critical Discourse Analysis, Ethnography, Virtual Ethnography, Corpus Analysis, Multimodality, Conversation Analysis, Narrative Analysis, Questionnaire and Interview. Assists readers in determining the most suitable method for various research questions, conceptualizing the research process, interpreting results, and drawing conclusions Supports students from start to finish with key terms, suggestions for further reading, research summaries, and sound guidance from experienced scholars and researchers

Anna Grzeszczuk HIV/AIDS Anna Grzeszczuk HIV/AIDS
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Anna Grzeszczuk HIV/AIDS


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643.11 руб.

Richard Crosby A. Research Methods in Health Promotion Richard Crosby A. Research Methods in Health Promotion
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Richard Crosby A. Research Methods in Health Promotion


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6748.95 руб.

The bestselling textbook to understanding health research, updated and expanded Research Methods in Health Promotion provides students and practitioners with essential knowledge and skills regarding the design, implementation, analysis, and interpretation of research in the field of health promotion. Now in its second edition, this bestselling textbook has been updated with more recent research methodologies and additional information on sampling, participatory and survey research, and qualitative data analysis. The entire research process is covered, with specific points relating to both qualitative and quantitative research. By breaking the daunting process of research into simple and well-defined steps, this user-friendly text encourages students to think about research as a sequential process and provides explanations that facilitate better understanding of each step in the research process. A separate set of chapters cover the more quantitative methodological areas including designs, measurement, sampling, and data analysis in depth, giving readers the understanding they need to apply in practice. This book also provides applied chapters that illustrate the practical aspects of the research process, along with other critical information including grant writing and scientific writing. Evaluate the ethics, design, analysis, and interpretation of research Identify and understand the key components of research studies Analyze and interpret the results of experimental and survey research designs Understand the process of publishing a research report and constructing a grant proposal Research Methods in Health Promotion is ideal for both undergrad and graduate methods courses in health promotion and public health.

Robert Hirsch P. Workbook to Accompany Introduction to Biostatistical Applications in Health Research with Microsoft Office Excel Robert Hirsch P. Workbook to Accompany Introduction to Biostatistical Applications in Health Research with Microsoft Office Excel
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Robert Hirsch P. Workbook to Accompany Introduction to Biostatistical Applications in Health Research with Microsoft Office Excel


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2621.03 руб.

Workbook to accompany Introduction to Biostatistical Applications in Health Research with Microsoft Office Excel—practical and methodological approach to the statistical logic of biostatistics in the field of health research.

Iona Murdoch Geriatric Emergencies Iona Murdoch Geriatric Emergencies
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Iona Murdoch Geriatric Emergencies


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5095.51 руб.

Geriatric Emergencies is a practical guide to the common conditions affecting older patients who present in an emergency to hospital or primary care. Beginning with the essentials of history taking and clinical examination, the book covers a comprehensive range of emergencies, emphasizing the different management approaches which may be required in older patients. Common geriatric presentations such as falls, delirium and stroke, are explored in detail in addition to more diverse topics such as abdominal pain, major trauma and head injury. Ethical considerations such as advanced care planning, palliative care and capacity assessment are discussed with practical tips on communicating with patients and their relatives. Geriatric Emergencies provides concise up-to-date guidance to the emergency management of the older patient. It is a recommended resource for all health professionals working in the acute environment, in which a large proportion of patients are aged over 65.

Matthews Tracey D. Designing and Conducting Research in Health and Human Performance Matthews Tracey D. Designing and Conducting Research in Health and Human Performance
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Matthews Tracey D. Designing and Conducting Research in Health and Human Performance


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6223.29 руб.

Designing and Conducting Research in Health and Human Performance shows students how to become effective producers and consumers of health and human performance research. The book provides comprehensive coverage of both quantitative and qualitative research methods and includes step-by-step guidance for writing effective research proposals and theses. In addition, the authors show how to read, assess, interpret, and apply published research and how to conduct basic studies in health, physical education, exercise science, athletic training, and recreation. Designing and Conducting Research in Health and Human Performance is filled with illustrative examples that emphasize the real-world applications of research methods. Throughout, the authors draw on a variety of examples that were selected because they provide a context to further the understanding of health and human performance research. Research to Practice examples and Tips are included by the authors to help students better appreciate the book's content. These study aids provide suggestions and additional resources to assist students in understanding the research process. Key Terms, defined and highlighted, enrich each chapter. Chapter Review Questions, designed to help students comprehend and follow best practices in research methods, close each chapter. Online resources and guides developed by the authors to support and enhance students' learning of important research concepts are available.

David Wang Architectural Research Methods David Wang Architectural Research Methods
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David Wang Architectural Research Methods


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5624.83 руб.

A practical guide to research for architects and designers—now updated and expanded! From searching for the best glass to prevent glare to determining how clients might react to the color choice for restaurant walls, research is a crucial tool that architects must master in order to effectively address the technical, aesthetic, and behavioral issues that arise in their work. This book's unique coverage of research methods is specifically targeted to help professional designers and researchers better conduct and understand research. Part I explores basic research issues and concepts, and includes chapters on relating theory to method and design to research. Part II gives a comprehensive treatment of specific strategies for investigating built forms. In all, the book covers seven types of research, including historical, qualitative, correlational, experimental, simulation, logical argumentation, and case studies and mixed methods. Features new to this edition include: Strategies for investigation, practical examples, and resources for additional information A look at current trends and innovations in research Coverage of design studio–based research that shows how strategies described in the book can be employed in real life A discussion of digital media and online research New and updated examples of research studies A new chapter on the relationship between design and research Architectural Research Methods is an essential reference for architecture students and researchers as well as architects, interior designers, landscape architects, and building product manufacturers.

Terrence Montague Patients First. Closing the Health Care Gap in Canada Terrence Montague Patients First. Closing the Health Care Gap in Canada
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Terrence Montague Patients First. Closing the Health Care Gap in Canada


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3888.91 руб.

PATIENTS FIRST CLOSING THE HEALTH CARE GAP IN CANADA «This book is a must read for those who are interested in our health care system and who want to make it better. Dr. Montague provides an interesting overview of his journey through hospital wards, clinical trials, patient registries, patient health management and chronic disease management programs. Drawing on his diverse and unique background, he gives an important history of the past, analysis of the present and a glimpse of our future.» –David Johnstone, MD President, Canadian Cardiovascular Society «Based on significant practice and research experience in the public, private and academic worlds, over many regions of Canada, Dr. Montague reveals to the reader, consumer, decision maker and patient an evolving and, until now, largely overlooked dimension in optimizing care and outcome. This optimization is important not only within the context of an individual's care, but within the scope of an entire practice, community or even nation.» –Ross Tsuyuki, PharmD Director, The Epidemiology Coordinating and Research Centre, University of Alberta «Listen to Dr. Montague. He well understands both the problem and the solution, which is to pull out all the stops and to put patients first. He advocates patient health management to close the many care gaps. This will result in improved health for millions of Canadians and then, if we do it right, by emphasizing research and evidence-based health care and not merely budgets, our health care system will become more cost effective and our population healthier and more productive.» –Mark Poznansky, PhD President, Robarts Research Institute

Valeriy Zhiglov Stay away from AIDS. Something one should know Valeriy Zhiglov Stay away from AIDS. Something one should know
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Valeriy Zhiglov Stay away from AIDS. Something one should know


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96 руб.

AIDS is a contagious disease, currently incurable. Dozens of millions of HIV-positive are already registered worldwide, and each year this number grows. In recent years, AIDS/HIV became a major problem both for people from «risk groups», and for ordinary people. The book gives a number of important recommendations on how to suppress further expansion of this dangerous disease.

Stuart A. Rice Advances in Chemical Physics Stuart A. Rice Advances in Chemical Physics
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Stuart A. Rice Advances in Chemical Physics


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14994.82 руб.

Advances in Chemical Physics is the only series of volumes available that explores the cutting edge of research in chemical physics. This is the only series of volumes available that presents the cutting edge of research in chemical physics. Includes contributions from experts in this field of research. Contains a representative cross-section of research that questions established thinking on chemical solutions. Structured with an editorial framework that makes the book an excellent supplement to an advanced graduate class in physical chemistry or chemical physics.

Okechukwu Ekenna Cases in Clinical Infectious Disease Practice Okechukwu Ekenna Cases in Clinical Infectious Disease Practice
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Okechukwu Ekenna Cases in Clinical Infectious Disease Practice


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11244.69 руб.

In the era of cost cutting and lack of adequate health insurance for many patients, clinical skills and time spent with patients are not adequately compensated. Yet, these dwindling and underpaid skills – good history taking, observation of and listening to patients, and physical examination of patients – remain very essential to making and reaching a complete and accurate diagnosis. Expensive laboratory and imaging diagnostics while very relevant, should not replace these age-old skills that have served to enhance and maintain the doctor-patient relationship and human connection, a connection that is often necessary for healing. Cases in Clinical Infectious Disease Practice uses case studies to illustrate how the infectious disease clinician processes and integrates data to arrive at a diagnosis. This type of hands-on approach, invaluable in training programs, is utilized to take the reader through initial patient encounter, through the history and physical examination, to simple laboratory findings and stains, to a final diagnosis, in a way that is easily accessible to clinicians, students, and laboratory personnel working with clinical specimens. Appeals to practitioners of all levels, with focus on patients with common problems or complications of common infections without heavy technical language Emphasizes basic clinical skills including history taking, observation, epidemiology, and physical exam, as well as simple laboratory tests, explaining how they lead to a reasonable diagnosis Presents cases seen first-hand within the community setting, reflective of cases or situations a resident or student is likely to encounter in the real world after training Cases in Clinical Infectious Disease Practice is an essential resource for clinicians, graduate and medical school students, and others conducting medical and clinical microbiology or infectious disease research on real patients.

Sharan Merriam B. Qualitative Research in Practice. Examples for Discussion and Analysis Sharan Merriam B. Qualitative Research in Practice. Examples for Discussion and Analysis
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Sharan Merriam B. Qualitative Research in Practice. Examples for Discussion and Analysis


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5414.26 руб.

A practical introduction to qualitative research across fields and disciplines Qualitative Research in Practice offers a hands-on introduction to qualitative research design, methods, data, and analysis. Designed as a companion text for any course involving qualitative research, this book explores the different types of qualitative studies with relevant examples and analysis by the researchers themselves. The workbook format makes it easy to use in the classroom or the field, and the depth of information makes it a valuable resource for students of social work, psychology, counseling, management, education, health care, or any field in which qualitative research is conducted. While quantitative research is primarily concerned with numerical data, qualitative research methods are more flexible, responsive, and open to contextual information. To a qualitative researcher, a situation is defined by the participants’ perspectives, making it the primary method of inquiry for understanding social phenomena through the lens of experience. This book introduces the essentials of qualitative research, bolstered by expert analysis and discussion that provides deeper insight than a traditional textbook format would allow. Understand the fundamental nature of qualitative research Learn how to accurately assess and evaluate qualitative research Explore qualitative research’s many forms and applications Gain insight on qualitative research in a variety of fields and disciplines How does one codify an experience? Is it possible to measure emotion in units? Qualitative research fills the void where numbers cannot reach. It is the best tool we have for studying the unquantifiable aspects of the human experience, and it is an essential tool in a wide variety of fields. Qualitative Research in Practice provides translatable skills in a practical format to quicken your transition from “learning” to “using.”


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Successful management of patients with treatment-resistant depression is going to require a thorough understanding of the biological basis for both the depression and its failure to respond to standard treatments. This book clearly and succinctly summarizes the latest scientific research and its applications in clinical practice. A first step is a clear definition of what constitutes treatment-resistant depression so that clinical trials and other studies are using common criteria, enabling comparison and meta-analysis of their outcomes. The opening chapter reviews definitions and predictors of originating from different fields and discusses their usefulness in clinical practice and clinical research. The next chapter proposes a new definition, adapting terminology from medicine. Biological classification requires identification of genetic risk factors: with gene variants accounting for 50% of the variance in the clinical outcomes of antidepressant treatments this is clearly a fruitful area of research. Chapter 3 describes several genes already associated with treatment-resistant depression and, while further work is needed to translate findings into clinical recommendations, predicts that genetic prediction of TRD could became a widespread clinical reality within a few years. Most patients with TRD will be treated pharmacologically and three chapters review the latest evidence for pharmacological best practice, including switching strategies for antidepressants, the role of antipsychotics and augmentation strategies to complement lithium. There are two major alternatives to pharmacotherapy: neuromodulation and psychotherapy. The brain intervention chapter summarizes clinical research and experience with electroconvulsive therapy, transcranial magnetic stimulation, vagus nerve stimulation, deep brain stimulation and magnetic seizure therapy. The final chapter reviews the literature pertaining to the effectiveness of various forms of psychotherapy in patients who have not responded to antidepressant pharmacotherapy, revealing that patients who have not responded to one or two trials of antidepressant medication have a 30%-50% chance of responding to a focused psychotherapy. It proposes indications for psychotherapy in TRD and summarizes general therapeutic principles.
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