synthesis of novel oxime hydrazone and thiosemicarbazone compounds



Capriati Vito Lithium Compounds in Organic Synthesis. From Fundamentals to Applications Capriati Vito Lithium Compounds in Organic Synthesis. From Fundamentals to Applications Новинка

Capriati Vito Lithium Compounds in Organic Synthesis. From Fundamentals to Applications

16737.54 руб. или Купить в рассрочку!
This unique book covers fundamentals of organolithium compounds and gives a comprehensive overview of the latest synthetic advances and developments in the field. Part I covers computational and spectroscopic aspects as well as structure-reactivity relationships of organolithiums, whereas Part II deals with new lithium-based synthetic methodologies as well as novel synthetic applications of functionalized lithium compounds. A useful resource for newcomers and active researchers involved in organic synthesis, whether working in academia or industry!
Alfred Sattelberger P. Inorganic Syntheses Alfred Sattelberger P. Inorganic Syntheses Новинка

Alfred Sattelberger P. Inorganic Syntheses

10787.31 руб. или Купить в рассрочку!
This volume of Inorganic Syntheses spans the preparations of wide range of important inorganic, organometallic and solid-state compounds. The volume is divided into 6 chapters. The first chapter contains the syntheses of some key early transition metal halide clusters and the very useful mononuclear molybdenum(III) synthon, MoCl3(THF)3. Chapter 2 covers the synthesis of a number of cyclopentadienyl compounds, including a novel route to sodium and potassium cyclopentadienide, MC5H5. Chapter 3 details synthetic procedures for a range of metal-metal bonded compounds, including several with metal-metal multiple bonds. Chapter 4 contains procedures for a range of early and late transition metal compounds, each a useful synthon for further synthetic elaboration. Chapter 5 deals with the synthesis of a number of main group compounds and ligands, while Chapter 6 covers teaching laboratory experiments.
Srinivasan Chandrasekaran Click Reactions in Organic Synthesis Srinivasan Chandrasekaran Click Reactions in Organic Synthesis Новинка

Srinivasan Chandrasekaran Click Reactions in Organic Synthesis

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This book on click reactions to focus on organic synthesis, this reference work describes the click concept and underlying mechanisms as well as the main applications in various fields. As such, the chapters cover green chemical synthesis, metal-free click reactions, synthesis of pharmaceuticals, peptides, carbohydrates, DNA, macrocycles, dendrimers, polymers, and supramolecular architectures. By filling a gap in the market, this is the ultimate reference for synthetic chemists in academia and industry aiming for a fast and simple design and synthesis of novel compounds with useful properties.
Christian Rojas M. Molecular Rearrangements in Organic Synthesis Christian Rojas M. Molecular Rearrangements in Organic Synthesis Новинка

Christian Rojas M. Molecular Rearrangements in Organic Synthesis

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Designed for practitioners of organic synthesis, this book helps chemists understand and take advantage of rearrangement reactions to enhance the synthesis of useful chemical compounds. Provides ready access to the genesis, mechanisms, and synthetic utility of rearrangement reactions Emphasizes strategic synthetic planning and implementation Covers 20 different rearrangement reactions Includes applications for synthesizing compounds useful as natural products, medicinal compounds, functional materials, and physical organic chemistry
Abou-Zied Ashraf Synthesis of some Important Heterocyclic Compounds via CT Interactions Abou-Zied Ashraf Synthesis of some Important Heterocyclic Compounds via CT Interactions Новинка

Abou-Zied Ashraf Synthesis of some Important Heterocyclic Compounds via CT Interactions

Synthesis of new heterocyclic compounds by using linear compounds as electron donors and some π-deficient compounds. The four compounds used as electron donors are: 1-acetylthiosemicarbazide; 1-benzoyl-thiosemicarbazide; 1-(4-hydroxyphenyl)thiosemicarbazide; 1-(4-bromo-phenylaceto)thiosemicarbazide. The π-deficient compounds, used are: ethenetetracarbonitrile TCNE; (1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)propanedinitrile CNIND; 3-(dicyano-methylene)-2-indolone; 7,7,8,8-tetracyanoquinodimethane TCNQ; 2,3-dichloro-5,6-dicyano-1,4-benzoquinone DDQ; 2,3,5,6-tetrachloro-1,4-benzoqinone CHL; 2,3-dichloro-1,4-naphthoquinone DCHNQ; 2,3-dicyano-1,4-naphthoqinone DCNQ.
Oleg Kolodiazhnyi I. Asymmetric Synthesis in Organophosphorus Chemistry. Synthetic Methods, Catalysis and Applications Oleg Kolodiazhnyi I. Asymmetric Synthesis in Organophosphorus Chemistry. Synthetic Methods, Catalysis and Applications Новинка

Oleg Kolodiazhnyi I. Asymmetric Synthesis in Organophosphorus Chemistry. Synthetic Methods, Catalysis and Applications

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Authored by one of the leading experts in the field, this is the only comprehensive overview of chiral organophosphorus compounds, from asymmetric synthesis to catalysis and pharmacological applications. As such, this unique reference covers the chemical background as well as spectroscopical analysis of phosphorus compounds, and thoroughly describes all the various synthetic strategies for these substances. Metal-, organo- and biocatalyzed reactions for the introduction of phosphorus are explained as are asymmetric oxidation and reduction methods for the preparation of all possible oxidation states of phosphorus. The text also includes industrial applications for these compounds. Of particular interest to chemists working in the field of asymmetric synthesis, as well as to the pharmaceutical industry due to the increasing number of phosphorous-containing drugs.
Vijay Kumar Singh, U. K. Sharma, Shobhit Singh Synthesis and Antimicrobial Activity of Benzotriazole Derivatives Vijay Kumar Singh, U. K. Sharma, Shobhit Singh Synthesis and Antimicrobial Activity of Benzotriazole Derivatives Новинка

Vijay Kumar Singh, U. K. Sharma, Shobhit Singh Synthesis and Antimicrobial Activity of Benzotriazole Derivatives

The practice of medicinal chemistry is devoted to the discovery and development of new chemical agents for treating disease. Most of the activity in this discipline is directed to the search of new natural or synthetic organic compounds. The present work emphasizes the synthesis of novel derivatives of benzotriazolothiadiazolyl thiazolidinones having three nuclei in combination with each other (viz. Benzotriazole, Thiadiazole and Thiazolidinone) along with their antimicrobial activity. The structure of synthesized compounds has been established on the basis of their physico-chemical properties and spectral data (I.R. and N.M.R. spectroscopy).
Krunalkumar R. Mehariya, Bhagwati K. Gauni Mehariya Synthesis, Characterization, and Single Crystal Structure of 4-(3-methoxy-4-(prop-2-yn-1-yloxy)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile Krunalkumar R. Mehariya, Bhagwati K. Gauni Mehariya Synthesis, Characterization, and Single Crystal Structure of 4-(3-methoxy-4-(prop-2-yn-1-yloxy)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile Новинка

Krunalkumar R. Mehariya, Bhagwati K. Gauni Mehariya Synthesis, Characterization, and Single Crystal Structure of 4-(3-methoxy-4-(prop-2-yn-1-yloxy)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile

Scientific Essay from the year 2010 in the subject Chemistry - General, , language: English, abstract: This paper deals with the synthesis of some novel 1,4-Dihydropyride derivatives derivatives. The 1,4-Dicyanopyride (DHPM ) derivatives have been synthesized through novel synthetic process. The synthesized compound was well characterized by IR, 1H NMR and 13C NMR, Mass spectrometry. To know the absolute configuration of the synthesized compounds, X-Ray crystallography study was also performed by developing the crystal of the compounds.
Yoshiki Chujo Conjugated Polymer Synthesis. Methods and Reactions Yoshiki Chujo Conjugated Polymer Synthesis. Methods and Reactions Новинка

Yoshiki Chujo Conjugated Polymer Synthesis. Methods and Reactions

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Edited and authored by top international experts, this first book on conjugated polymers with a focus on synthesis provides a detailed overview of all modern synthetic methods for these highly interesting compounds. As such, it describes every important compound class, including polysilanes, organoboron compounds, and ferrocene-containing conjugated polymers. An indispensable source for every synthetic polymer chemist.
Thomas Wirth Organoselenium Chemistry. Synthesis and Reactions Thomas Wirth Organoselenium Chemistry. Synthesis and Reactions Новинка

Thomas Wirth Organoselenium Chemistry. Synthesis and Reactions

2107.27 руб. или Купить в рассрочку!
Selenium-based methods in synthetic chemistry have developed rapidly over the past years and are now offering highly useful tools for organic synthesis. Filling the gap for a comprehensive handbook and ready reference, this book covers all modern developments within the field, including biochemical aspects. The chemistry chapters are organized according to the different reactivities of various selenium compounds and reagents, with each chapter dealing with a special reaction type. Also includes a table with 77Se NMR shifts to aid in practical problems. From the Contents: * Electrophilic and Nucleophilic Selenium * Selenium Compounds in Radical Reactions * Selenium-Stabilized Carbanions * Selenium Compounds with Valency Higher than Two * Selenocarbonyls * Selenoxide Elimination and [2,3]-Sigmatropic Rearrangement * Selenium Compounds as Ligands and Catalysts * Biological and Biochemical Aspects of Selenium Compounds
Kamran T. Mahmudov Non-covalent Interactions in the Synthesis and Design of New Compounds Kamran T. Mahmudov Non-covalent Interactions in the Synthesis and Design of New Compounds Новинка

Kamran T. Mahmudov Non-covalent Interactions in the Synthesis and Design of New Compounds

14512.52 руб. или Купить в рассрочку!
This book aims to overview the role of non-covalent interactions, such as hydrogen and halogen bonding, π-π, π-anion and electrostatic interactions, hydrophobic effects and van der Waals forces in the synthesis of organic and inorganic compounds, as well as in design of new crystals and function materials. The proposed book should allow to combine, in a systematic way, recent advances on the application of non-covalent interactions in synthesis and design of new compounds and functional materials with significance in Inorganic, Organic, Coordination, Organometallic, Pharmaceutical, Biological and Material Chemistries. Therefore, it should present a multi- and interdisciplinary character assuring a rather broad scope. We believe it will be of interest to a wide range of academic and research staff concerning the synthesis of new compounds, catalysis and materials. Each chapter will be written by authors who are well known experts in their respective fields.
Toshio Fuchigami Fundamentals and Applications of Organic Electrochemistry. Synthesis, Materials, Devices Toshio Fuchigami Fundamentals and Applications of Organic Electrochemistry. Synthesis, Materials, Devices Новинка

Toshio Fuchigami Fundamentals and Applications of Organic Electrochemistry. Synthesis, Materials, Devices

7739.92 руб. или Купить в рассрочку!
This textbook is an accessible overview of the broad field of organic electrochemistry, covering the fundamentals and applications of contemporary organic electrochemistry. The book begins with an introduction to the fundamental aspects of electrode electron transfer and methods for the electrochemical measurement of organic molecules. It then goes on to discuss organic electrosynthesis of molecules and macromolecules, including detailed experimental information for the electrochemical synthesis of organic compounds and conducting polymers. Later chapters highlight new methodology for organic electrochemical synthesis, for example electrolysis in ionic liquids, the application to organic electronic devices such as solar cells and LEDs, and examples of commercialized organic electrode processes. Appendices present useful supplementary information including experimental examples of organic electrosynthesis, and tables of physical data (redox potentials of various organic solvents and organic compounds and physical properties of various organic solvents).
Robin Hicks Stable Radicals. Fundamentals and Applied Aspects of Odd-Electron Compounds Robin Hicks Stable Radicals. Fundamentals and Applied Aspects of Odd-Electron Compounds Новинка

Robin Hicks Stable Radicals. Fundamentals and Applied Aspects of Odd-Electron Compounds

16511.36 руб. или Купить в рассрочку!
Stable radicals – molecules with odd electrons which are sufficiently long lived to be studied or isolated using conventional techniques – have enjoyed a long history and are of current interest for a broad array of fundamental and applied reasons, for example to study and drive novel chemical reactions, in the development of rechargeable batteries or the study of free radical reactions in the body. In Stable Radicals: Fundamentals and Applied Aspects of Odd-Electron Compounds a team of international experts provide a broad-based overview of stable radicals, from the fundamental aspects of specific classes of stable neutral radicals to their wide range of applications including synthesis, materials science and chemical biology. Topics covered include: triphenylmethyl and related radicals polychlorinated triphenylmethyl radicals: towards multifunctional molecular materials phenalenyls, cyclopentadienyls, and other carbon-centered radicals the nitrogen oxides: persistent radicals and van der Waals complex dimers nitroxide radicals: properties, synthesis and applications the only stable organic sigma radicals: di-tert-alkyliminoxyls. delocalized radicals containing the hydrazyl [R2N-NR] unit metal-coordinated phenoxyl radicals stable radicals containing the thiazyl unit: synthesis, chemical, and materials properties stable radicals of the heavy p-block elements application of stable radicals as mediators in living-radical polymerization nitroxide-catalyzed alcohol oxidations in organic synthesis metal-nitroxide complexes: synthesis and magneto-structural correlations rechargeable batteries using robust but redox-active organic radicals spin labeling: a modern perspective functional in vivo EPR spectroscopy and imaging using nitroxides and trityl radicals biologically relevant chemistry of nitroxides Stable Free Radicals: Fundamentals and Applied Aspects of Odd-Electron Compounds is an essential guide to this fascinating area of chemistry for researchers and students working in organic and physical chemistry and materials science.
Goswami K. V., Goswami T. K., Vyas S. P. Novel Chalchone Derivetives Goswami K. V., Goswami T. K., Vyas S. P. Novel Chalchone Derivetives Новинка

Goswami K. V., Goswami T. K., Vyas S. P. Novel Chalchone Derivetives

The chemistry of chalcone has been recognized as a significant field of study.Chalcones are the compounds where aromatic substituent are introduced into the terminal position of the system -C=C-C=O. So, chalcones are characterized by their possession of a structure in which two aromatic rings A and B are linked by an aliphatic three-carbon chain [(A) Ar-CO-CH=CH-Ar (B)]. An interesting feature of chalcone is that it serves as starting materials for the synthesis of various heterocyclic compounds such as pyrimidines, pyrazolines, pyrazoles, flavones, flavonols, flavanones, aurones and benzoyl coumarones as well as certain compounds like deoxybenzoins and hydantoins, which are of some therapeutic value.
Erick Vandamme J. Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants Erick Vandamme J. Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants Новинка

Erick Vandamme J. Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants

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Vitamins are a group of physiologically very important, chemically quite complex organic compounds, that are essential for humans and animals. Some vitamins and other growth factors behave as antioxidants, while some can be considered as biopigments. As their chemical synthesis is laborious, their biotechnology-based synthesis and production via microbial fermentation has gained substantial interest within the last decades. Recent progress in microbial genetics and in metabolic engineering and implementation of innovative bioprocess technology has led to a biotechnology-based industrial production of many vitamins and related compounds. Divided into three sections, this volume covers: 1. water-soluble vitamins 2. fat-soluble vitamin compounds and 3. other growth factors, biopigments, and antioxidants. They are all reviewed systematically: from natural occurrence and assays, via biosynthesis, strain development, to industrially-employed biotechnological syntheses and applications.
Desha Lucius Junius On the mechanism of oxime formation and hydrolysis and the use of the hydrogen electrode in the presence of certain organic compounds Desha Lucius Junius On the mechanism of oxime formation and hydrolysis and the use of the hydrogen electrode in the presence of certain organic compounds Новинка

Desha Lucius Junius On the mechanism of oxime formation and hydrolysis and the use of the hydrogen electrode in the presence of certain organic compounds

Эта книга — репринт оригинального издания, созданный на основе электронной копии высокого разрешения, которую очистили и обработали вручную, сохранив структуру и орфографию оригинального издания. Редкие, забытые и малоизвестные книги, изданные с петровских времен до наших дней, вновь доступны в виде печатных книг.
Pher Andersson G. Innovative Catalysis in Organic Synthesis. Oxidation, Hydrogenation, and C-X Bond Forming Reactions Pher Andersson G. Innovative Catalysis in Organic Synthesis. Oxidation, Hydrogenation, and C-X Bond Forming Reactions Новинка

Pher Andersson G. Innovative Catalysis in Organic Synthesis. Oxidation, Hydrogenation, and C-X Bond Forming Reactions

2107.27 руб. или Купить в рассрочку!
C-H, C-O, C-C, and C-Heteroatom bond forming processes by using metal-ligand approaches for the synthesis of organic compounds of biological, pharmacological and organic nanotechnological utility are the key areas addressed in this book. Authored by a European team of leaders in the field, it brings together innovative approaches for a variety of catalysis reactions and processes frequently applied in organic synthesis into a handy reference work. It covers all major types of catalysis, including homogeneous, heterogeneous, and organocatalysis, as well as mechanistic and computational studies. Special attention is paid to the improvements in efficiency and sustainability of important catalytic processes, such as selective oxidations, hydrogenation, and cross-coupling reactions, and to their utilization in industry. The result is a valuable resource for advanced researchers in both academia and industry, as well as graduate students in organic chemistry aiming for chemo-, regio- or stereoselective synthesis of organic compounds by using novel catalytic systems.
Van Nguyen Tang Recovering Bioactive Compounds from Agricultural Wastes Van Nguyen Tang Recovering Bioactive Compounds from Agricultural Wastes Новинка

Van Nguyen Tang Recovering Bioactive Compounds from Agricultural Wastes

11162.94 руб. или Купить в рассрочку!
A guide to the extraction, isolation and purification of bioactive compounds from agricultural wastes, and their applications Recovering Bioactive Compounds from Agricultural Wastes offers a guide to the many uses of agricultural wastes from the production of major food types including tea, coffee, cacao, cashew, fruit and vegetables, wine, edible oils, sugar, starch and more. Written by a noted expert in the field, the text explores the various methods for extraction, isolation and purification of bioactive compounds from agricultural wastes. The author also makes recommendations concerning the most effective applications of bioactive compounds and discusses the economics and market for recovered bioactive compounds. Recent studies reveal that bioactive compounds have been directly linked to biological activity such as antioxidant, anticancer, antidiabetic, anti-cardiovascular capacities, etc. In particular, agricultural wastes are considered as potential and inexpensive sources of bioactive compounds. Recovering Bioactive Compounds from Agricultural Wastes fills a gap in the literature by providing a text that explores this important topic and examines the: Sustainability of waste management and shows how to extract, isolate and purify bioactive compounds from agricultural wastes, and their most effective application Wide range of agricultural food produce that can be processed and the special techniques used for recovering the bioactive compounds from these sources Health applications of bioactive compounds that have been directly linked to pharmacological activities including antioxidant, anticancer, and more Designed for use by researchers and producers in the agriculture, pharmaceuticals and nutraceuticals, Recovering Bioactive Compounds from Agricultural Wastes contains the knowledge, history and definition, classification and synthesis, and extraction techniques of bioactive compounds.
David Rowe Chemistry and Technology of Flavours and Fragrances David Rowe Chemistry and Technology of Flavours and Fragrances Новинка

David Rowe Chemistry and Technology of Flavours and Fragrances

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Modern flavours and fragrances are complex formulated products, containing blends of aroma compounds with auxiliary materials, enabling desirable flavours or fragrances to be added to a huge range of products. From the identification and synthesis of materials such as cinnamaldehyde and vanillin in the 19th Century to the current application of advanced analytical techniques for identification of trace aroma compounds present in natural materials, the flavour and fragrance industry has developed as a key part of the worldwide specialty chemicals industry. With contributions mainly coming from industry based experts, Chemistry & Technology of Flavours and Fragrances provides a detailed overview of the synthesis, chemistry and application technology of the major classes aroma compounds. With separate chapters covering important technical aspects such as the stability of aroma compounds, structure – odour relationships and identification of aroma compounds, this book will be essential reading for both experienced and graduate level entrants to the flavour & fragrance industry. It will also serve as an important introduction to the subject for chemists and technologists in those industries that use flavours and fragrances, eg food, cosmetics & toiletries, and household products. David Rowe is Technical Manager at De Monchy Aromatics Ltd., Poole UK
Swapna Suresh Multi-Step Synthesis of Solid Support with Protected 5.-Aminouridine Swapna Suresh Multi-Step Synthesis of Solid Support with Protected 5.-Aminouridine Новинка

Swapna Suresh Multi-Step Synthesis of Solid Support with Protected 5.-Aminouridine

During my M.S. thesis work I was involved in a multistep synthesis of solid support bearing a modified nucleoside for automated synthesis of siRNAs. First, I developed a three-step synthesis of protected 5'-amino uridine from uridine. Next I prepared the 3'-succinate of 5'-amino uridine in a one-pot two-step synthesis and attached it to a solid support via a succinamide linker. I had analyzed and characterized all new compounds using NMR techniques. Others in our laboratory used this solid support for synthesis of amide-modified siRNAs. We anticipate that the amide linkages will facilitate crossing the cellular membrane and improve nuclease resistance, biodistribution and pharmacokinetics of modified siRNAs.
John Tebby C. Alkynes in Cycloadditions John Tebby C. Alkynes in Cycloadditions Новинка

John Tebby C. Alkynes in Cycloadditions

14586.66 руб. или Купить в рассрочку!
Acetylene systems present a new route to cyclic compounds as an alternative to more traditional methods employed in classical organic chemistry. The synthesis of cyclic structures based on acetylene systems has important applications in the formation of nanostructures, naturally occurring compounds and chemosensory materials for the design of nonlinear optics, electronic and photonic devices. Alkynes in Cycloadditions presents a modern review of regioselective synthesis of aromatic and non-aromatic carbocyclic and heterocyclic ring systems based primarily on [2+2+2] and [4+2] cycloadditions, and other reactions of acetylenic units including enediynes and enyne-allenes. Topics covered include: New strategies for the formation of aromatic and polynuclear hydrocarbons based on (Z)-hex-3-en-1,5-diyne and (Z)-hepta-1,2,4-triene-6-yne blocks. One-step synthesis of benzene derivatives, β-substituted naphthalenes and acenes by the cycloaromatization of enediynes and enyne-allenes by Bergman, Myers-Saito and Shmittel. Mechanisms of cycloaromatization resulting in the formation of fulvene and indene systems. Heterocyclization involving enyne-carbodiimides. New achievements in classical cycloaddition reactions such as the Diels-Alder condensation with acetylenic dienophiles and [2+2] cycloadditions with acetylene components Alkynes in Cycloadditions presents a comprehensive summary of the literature on methods for the synthesis of ring systems from acetylenes for academic researchers working in the fields of organic synthesis, physical organic chemistry, organometallic chemistry, catalysis, materials science, nanomaterials and biochemistry.
Vora Jabali J., Parmar Ketan C., Patel Dharmesh Synthesis of sulfur based Chalcone Derivatives Vora Jabali J., Parmar Ketan C., Patel Dharmesh Synthesis of sulfur based Chalcone Derivatives Новинка

Vora Jabali J., Parmar Ketan C., Patel Dharmesh Synthesis of sulfur based Chalcone Derivatives

This book is consist of mainly two chapter. The first chapter is for general introduction of drugs, which generally narrates about heterocyclic compounds. The second chapter is for synthesis and characterization of chalcones as well as antimicrobial activity of synthesized chalcones. This book is useful to the research students who ever working in the field of synthetic organic chemistry(heterocyclic compounds).
Ken Tanaka Transition-Metal-Mediated Aromatic Ring Construction Ken Tanaka Transition-Metal-Mediated Aromatic Ring Construction Новинка

Ken Tanaka Transition-Metal-Mediated Aromatic Ring Construction

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State-of-the-science methods, synthetic routes, and strategies to construct aromatic rings The development of new reactions for the synthesis of aromatic compounds is a highly active research area in organic synthesis, providing new functional organic materials, functional reagents, and biologically active compounds. Recently, significant advances in transition-metal-mediated reactions have enabled the efficient and practical construction of new aromatic rings with useful properties and applications. This book draws together and reviews all the latest discoveries and methods in transition-metal-mediated reactions, offering readers promising new routes to design and construct complex aromatic compounds. Integrating metal catalysis with aromatic compound synthesis, Transition-Metal-Mediated Aromatic Ring Construction offers a practical guide to the methods, synthetic routes, and strategies for constructing aromatic compounds. The book's five parts examine: [2+2+2], [2+2+1], and related cycloaddition reactions [4+2], [3+2], and related cycloaddition reactions Electrocyclization reactions Coupling and addition reactions Other important transformations, including methathesis reactions and skeletal rearrangement reactions Edited by Ken Tanaka, an internationally recognized expert in the field of transition-metal catalysis, the book features authors who are leading pioneers and researchers in synthetic reactions. Their contributions reflect a thorough review and analysis of the literature as well as their own firsthand laboratory experience developing new aromatic compounds. All chapters end with a summary and outlook, setting forth new avenues of research and forecasting new discoveries. There are also references at the end of each chapter, guiding readers to important original research reports and reviews. In summary, Transition-Metal-Mediated Aromatic Ring Construction offers synthetic chemists a promising new avenue for the development of important new aromatic compounds with a broad range of applications.
Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology Новинка

Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology

10932.18 руб. или Купить в рассрочку!
This book covers important advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. Advances in Enzymology focuses on enzymes, the primary catalysts of life processes. The explanation of the behavior of enzymes can be found via studies of their chemical mechanisms and can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. The transglutaminases, first described in 1957, are a large, widely-distributed family of enzymes canonically responsible for the amidation/transamidation of protein side chains. The extraordinary diversity of names associated with various enzymatic activities now recognized and aggregated as transglutaminase bears witness to the remarkable diversity of biological roles associated with the activity, including myriad human diseases.
Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology Новинка

Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology

16373.01 руб. или Купить в рассрочку!
Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.
Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology Новинка

Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology

10932.18 руб. или Купить в рассрочку!
This book covers important advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes.
Mario Clerici G. Liquid Phase Oxidation via Heterogeneous Catalysis. Organic Synthesis and Industrial Applications Mario Clerici G. Liquid Phase Oxidation via Heterogeneous Catalysis. Organic Synthesis and Industrial Applications Новинка

Mario Clerici G. Liquid Phase Oxidation via Heterogeneous Catalysis. Organic Synthesis and Industrial Applications

11907.84 руб. или Купить в рассрочку!
Sets the stage for environmentally friendly industrial organic syntheses From basic principles to new and emerging industrial applications, this book offers comprehensive coverage of heterogeneous liquid-phase selective oxidation catalysis. It fully examines the synthesis, characterization, and application of catalytic materials for environmentally friendly organic syntheses. Readers will find coverage of all the important classes of catalysts, with an emphasis on their stability and reusability. Liquid Phase Oxidation via Heterogeneous Catalysis features contributions from an international team of leading chemists representing both industry and academia. The book begins with a chapter on environmentally benign oxidants and then covers: Selective oxidations catalyzed by TS-1 and other metal-substituted zeolites Selective catalytic oxidation over ordered nanoporous metallo-aluminophosphates Selective oxidations catalyzed by mesoporous metal-silicates Liquid phase oxidation of organic compounds by supported metal-based catalysts Selective liquid phase oxidations in the presence of supported polyoxometalates Selective oxidations catalyzed by supported metal complexes Liquid phase oxidation of organic compounds by metal-organic frameworks Heterogeneous photocatalysis for selective oxidations with molecular oxygen All the chapters dedicated to specific types of catalysts follow a similar organization and structure, making it easy to compare the advantages and disadvantages of different catalysts. The final chapter examines the latest industrial applications, such as the production of catechol and hydroquinone, cyclohexanone oxime, and propylene oxide. With its unique focus on liquid phase heterogeneous oxidation catalysis, this book enables researchers in organic synthesis and oxidation catalysis to explore and develop promising new catalytic materials and synthetic routes for a broad range of industrial applications.
SELCUK CALIMSIZ Total Synthesis of Callipeltin E and Towards Papuamide B SELCUK CALIMSIZ Total Synthesis of Callipeltin E and Towards Papuamide B Новинка

SELCUK CALIMSIZ Total Synthesis of Callipeltin E and Towards Papuamide B

Callipeltins and Papuamides -novel families of cyclic depsipeptides- were shown to possess potent anti-HIV activity as well as cytotoxicity against several multidrug resistant cancer cell lines. The novel structural features and diverse biological effects of these peptides metabolites have generated considerable interest among synthetic chemistry groups. In this book, discovery of the lanthanide catalyzed transamidation of Fmoc protected lactams, solid-phase synthesis and configurational reassignment of Callipeltin E, synthesis of N-Fmoc- (2S,3S,4R)-3,4-dimethylglutamine and an efficient method for the on-resin synthesis and macrocylization of a simplified Papuamide B model system are summarized.
Ji Zhang Macrocyclic Polyamines. Synthesis and Applications Ji Zhang Macrocyclic Polyamines. Synthesis and Applications Новинка

Ji Zhang Macrocyclic Polyamines. Synthesis and Applications

12279.93 руб. или Купить в рассрочку!
The first comprehensive book focusing on synthesis and applications of macrocyclic polyamines and their derivatives Macrocyclic polyamines are a class of widely used important compounds. This is the first book that systematically summarizes the synthesis and applications of macrocyclic polyamines and their analogues, including the properties and synthetic methods of macrocyclic polyamines, chemical nucleases based on macrocyclic polyamines, the derivatives of macrocyclic polyamines as nano-vector materials, macrocyclic polyamines derivatives for bio-imaging, chemical sensors based on macrocyclic polyamines, and other applications of macrocyclic polyamines. Macrocyclic Polyamines: Synthesis and Applications includes most of the studies involving macrocyclic polyamines and their derivatives, and may be used as a reference for the researchers in related fields. It offers in-depth coverage of cyclization modes; special procedures for tetraza macrocyclic compounds; diacids-diamines condensation; oxidative DNA cleaving by macrocyclic polyamines; lipids with cationic MPA headgroups; the derivatives of DOTA, DO3A, and PCTA; receptors for anions; sensors for bioactive molecules; macrocyclic polyamines for solvent extraction and membrane transport of amino acids and their derivatives, electrophoretic separation, and open-tubular CEC; and much more. The first book that systematically summarizes the chemistry of macrocyclic polyamines and their derivatives in terms of synthetic methods for their preparation, functionalization, and application in the main fields of chemical sensors, chemical nucleases, drug-delivery, bio-imaging and vector materials Provides a comprehensive reference for the researchers working on macrocyclic polyamines Offers train of thought in related research fields such as organic chemistry, coordination chemistry, analytical chemistry, supramolecular chemistry, biomaterials, etc. Macrocyclic Polyamines: Synthesis and Applications will not only provide a reference for the researchers working on macrocyclic polyamines, but also offer opportunities for researchers in related research fields to understand the benefits of these key compounds.
Patel Tarun, Shah Shailesh, A. M. Patel Novel Heterocyclic Compounds-2 Patel Tarun, Shah Shailesh, A. M. Patel Novel Heterocyclic Compounds-2 Новинка

Patel Tarun, Shah Shailesh, A. M. Patel Novel Heterocyclic Compounds-2

Introductory: The books is suggested that it is appropriate to give the brief note about hereto cyclic compounds bearing Trazine, Altretamine, Triethylenemelamine, Melamine, Atrazine, 4-aminobenzene-1-sulfonyl chloride and azetidinone derivatives disussions.this book is useful for those researcher who are involved to work in such compounds. Heterocyclic compounds of melamine work is also included in this book.
Quin Louis D. Fundamentals of Heterocyclic Chemistry. Importance in Nature and in the Synthesis of Pharmaceuticals Quin Louis D. Fundamentals of Heterocyclic Chemistry. Importance in Nature and in the Synthesis of Pharmaceuticals Новинка

Quin Louis D. Fundamentals of Heterocyclic Chemistry. Importance in Nature and in the Synthesis of Pharmaceuticals

7309.48 руб. или Купить в рассрочку!
Heterocyclic chemistry is of prime importance as a sub-discipline of Organic Chemistry, as millions of heterocyclic compounds are known with more being synthesized regularly Introduces students to heterocyclic chemistry and synthesis with practical examples of applied methodology Emphasizes natural product and pharmaceutical applications Provides graduate students and researchers in the pharmaceutical and related sciences with a background in the field Includes problem sets with several chapters
Purvesh Shah Organic preparation based on name reaction Purvesh Shah Organic preparation based on name reaction Новинка

Purvesh Shah Organic preparation based on name reaction

Document from the year 2013 in the subject Chemistry - Organic Chemistry, grade: A-C, , language: English, abstract: In "Organic Preparation based on some name reactions", I discuss some laboratory methods for preparation of some organic compounds based on name reaction like, Claisen-Schmidt Reaction, Beckmann Rearrangement, Diels-Alder Reaction, Pechmann Condensation, Fischer Indole Synthesis, Haloform Reaction, Knorr Quinoline Synthesis, Kolbe - Schmitt Reaction, etc.In the last chapter there is a discussion about Purification of organic compounds and their various methods.
Liebman Joel F. The Chemistry of Hydroxylamines, Oximes and Hydroxamic Acids, Volume 1 Liebman Joel F. The Chemistry of Hydroxylamines, Oximes and Hydroxamic Acids, Volume 1 Новинка

Liebman Joel F. The Chemistry of Hydroxylamines, Oximes and Hydroxamic Acids, Volume 1

163982.65 руб. или Купить в рассрочку!
Focusing on an important class of compounds in organic synthesis, this text features contributions by leading experts, and delivers the quality expected from the “Patai Series.”
Lee Vladimir Ya. Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb. From Phantom Species to Stable Compounds Lee Vladimir Ya. Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb. From Phantom Species to Stable Compounds Новинка

Lee Vladimir Ya. Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb. From Phantom Species to Stable Compounds

16511.36 руб. или Купить в рассрочку!
Until recently the low-coordinate compounds of the heavier elements of group 14 were known only as transient, unstable species which were difficult to isolate. However recent developments have led to the stabilisation of these compounds and today heavier group 14 element cations, radicals, anions, carbene analogues, alkene and alkyne analogues and aromatics have all been prepared as highly reactive, stable, fully characterizable and readily available organometallic reagents. Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb describes the chemistry of this exciting new class of organometallics, with an emphasis on their major similarities and differences with the analogous species in organic chemistry. Topics covered include include the synthesis, structure, reactions and synthetic applications of : Si-, Ge-, Sn and Pb-centered cations, radicals and anions heavy analogues of carbenes: silylenes, germylenes, stannylenes and plumbylenes heavy analogues of alkenes: disilenes, digermenes, distannenes, diplumbenes heavy analogues of alkynes: disilynes, digermynes, distannynes, diplumbynes, and their valence isomers heteronuclear derivatives: silenes, germenes, stannenes, silagermenes, silastannenes, germastannenes heavy analogues of alkenes of the type: >E14=E13-, >E14=E15-, >E14=E16 [where E13, E14, E15 and E16 are elements of the groups 13, 14, 15 and 16] cyclic compounds (three-, four-, five-, and six-membered rings) heavy analogues of 1,3-dienes, allenes and other cumulenes heavy analogues of aromatic compounds; including a comparison between organometallic and organic aromaticity Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb is an essential guide to this emerging class of organometallic reagents for researchers and students in main group, organometallic, synthetic and silicon chemistry
Ari M. P. Koskinen Asymmetric Synthesis of Natural Products Ari M. P. Koskinen Asymmetric Synthesis of Natural Products Новинка

Ari M. P. Koskinen Asymmetric Synthesis of Natural Products

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Asymmetric Synthesis of Natural Products, 2nd Edition introduces students to this rapidly growing field of organic chemistry. The initial chapters present the foundations of asymmetric synthesis, including the theory and applications of individual asymmetric reactions. This is followed by chapters on each of the major individual classes of natural products; their structures, biosynthesis and interrelationships as well as examples of asymmetric syntheses and the practical value of these compounds. Natural product classes covered include carbohydrates, amino acids, peptides, proteins, nucleosides, nucleotides, nucleic acids, polyketides, isoprenoids, shikamic acid derivatives and alkaloids. For this second edition the text has been thoroughly updated and expanded, and includes new discussions and examples covering atom and redox economies, practical aspects and environmental awareness. Organocatalysis has emerged completely in the last ten years, and has been fully integrated into this new edition.
Pedro Merino Chemical Synthesis of Nucleoside Analogues Pedro Merino Chemical Synthesis of Nucleoside Analogues Новинка

Pedro Merino Chemical Synthesis of Nucleoside Analogues

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Compiles current tested and proven approaches to synthesize novel nucleoside analogues Featuring contributions from leading synthetic chemists from around the world, this book brings together and describes tested and proven approaches for the chemical synthesis of common families of nucleoside analogues. Readers will learn to create new nucleoside analogues with desired therapeutic properties by using a variety of methods to chemically modify natural nucleosides, including: Changes to the heterocyclic base Modification of substituents at the sugar ring Replacement of the furanose ring by a different carbo- or heterocyclic ring Introduction of conformational restrictions Synthesis of enantiomers Preparation of hydrolitically stable C-nucleosides Chemical Synthesis of Nucleoside Analogues covers all the major classes of nucleosides, including pronucleotides, C-nucleosides, carbanucleosides, and PNA monomers which have shown great promise as starting points for the synthesis of nucleoside analogues. The book also includes experimental procedures for key reactions related to the synthesis of nucleoside analogues, providing a valuable tool for the preparation of a number of different compounds. Throughout the book, chemical schemes and figures help readers better understand the chemical structures of nucleoside analogues and the methods used to synthesize them. Extensive references serve as a gateway to the growing body of original research studies and reviews in the field. Synthetically modified nucleosides have proven their value as therapeutic drugs, in particular as antiviral and antitumor agents. However, many of these nucleoside analogues have undesirable side effects. With Chemical Synthesis of Nucleoside Analogues as their guide, researchers have a new tool for synthesizing a new generation of nucleoside analogues that can be used as therapeutic drugs with fewer unwanted side effects.
Wyatt Paul Workbook for Organic Synthesis: The Disconnection Approach Wyatt Paul Workbook for Organic Synthesis: The Disconnection Approach Новинка

Wyatt Paul Workbook for Organic Synthesis: The Disconnection Approach

13721.77 руб. или Купить в рассрочку!
One approach to organic synthesis is retrosynthetic analysis. With this approach chemists start with the structures of their target molecules and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Workbook for Organic Synthesis: The Disconnection Approach, 2nd Edition This workbook provides a comprehensive graded set of problems to illustrate and develop the themes of each of the chapters in the textbook Organic Synthesis: The Disconnection Approach, 2nd Edition. Each problem is followed by a fully explained solution and discussion. The examples extend the student’s experience of the types of molecules being synthesised by organic chemists, and the strategies they employ to control their syntheses. By working through these examples students will develop their skills in analysing synthetic challenges, and build a toolkit of strategies for planning new syntheses. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. Together the workbook and textbook provide a complete course in retrosynthetic analysis. Organic Synthesis: The Disconnection Approach, 2nd Edition There are forty chapters in Organic Synthesis: The Disconnection Approach, 2nd Edition: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. In its second edition updated examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, Organic Synthesis: Strategy and Control. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Workbook for Organic Synthesis: The Disconnection Approach, 2nd edition, combined with the main textbook, provides a full course in retrosynthetic analysis for chemistry and biochemistry students, and a refresher course for organic chemists working in industry and academia.
Laurie Starkey S. Introduction to Strategies for Organic Synthesis Laurie Starkey S. Introduction to Strategies for Organic Synthesis Новинка

Laurie Starkey S. Introduction to Strategies for Organic Synthesis

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The stepping-stone text for students with a preliminary knowledge of organic chemistry looking to move into organic synthesis research and graduate-level coursework Organic synthesis is an advanced but important field of organic chemistry, however resources for advanced undergraduates and graduate students moving from introductory organic chemistry courses to organic synthesis research are scarce. Introduction to Strategies for Organic Synthesis is designed to fill this void, teaching practical skills for making logical retrosynthetic disconnections, while reviewing basic organic transformations, reactions, and reactivities. Divided into seven parts that include sections on Retrosynthesis and Protective Groups; Overview of Organic Transformations; Synthesis of Monofunctional Target Molecules; Synthesis of Target Molecules with Two Functional Groups; Synthesis of Aromatic Target Molecules; Synthesis of Compounds Containing Rings; and Predicting and Controlling Stereochemistry, the book covers everything students need to successfully perform retrosynthetic analyses of target molecule synthesis. Starting with a review of functional group transformations, reagents, and reaction mechanisms, the book demonstrates how to plan a synthesis, explaining functional group analysis and strategic disconnections. Incorporating a review of the organic reactions covered, it also demonstrates each reaction from a synthetic chemist's point of view, to provide students with a clearer understanding of how retrosynthetic disconnections are made. Including detailed solutions to over 300 problems, worked-through examples and end-of-chapter comprehension problems, Introduction to Strategies for Organic Synthesis serves as a stepping stone for students with an introductory knowledge of organic chemistry looking to progress to more advanced synthetic concepts and methodologies.
Roy Rushikesh Syhthesis Of Pyrido-.2,3-d. Pyrimidine 2-one Derivatives Roy Rushikesh Syhthesis Of Pyrido-.2,3-d. Pyrimidine 2-one Derivatives Новинка

Roy Rushikesh Syhthesis Of Pyrido-.2,3-d. Pyrimidine 2-one Derivatives

Over the last few years research has become more and more important due to its usefulness of society.This bool contain synthesis of heterocyclic compounds specially chalcones and various cyanoamine pyridines. This book mainly focus in synthesis of various pyrido[2,3-d]pyrimdine-2-one derivatives, characterization and biological activity of synthesized compounds.This book is useful for research students for whoever work in the field of organic chemistry.
Karim Rubaba The Targeting of Cypd to Identify Novel Cardioprotective Agent Karim Rubaba The Targeting of Cypd to Identify Novel Cardioprotective Agent Новинка

Karim Rubaba The Targeting of Cypd to Identify Novel Cardioprotective Agent

The aim of this book is to provide novel hits for the target CypD that could be used with further optimization in future as the potential therapeutic strategy against cardiovascular disease. The study involved both in silico and in vitro analysis. To do this, fluorescence-based thermal shift assay was employed to screen compounds against CypD that were identified by computer aided docking screen (virtual screening). The assay revealed in vitro interactions (based on the binding affinity) of these novel compounds with the protein target (CypD).
Anthonia O'Donovan Biotechnology of Bioactive Compounds. Sources and Applications Anthonia O'Donovan Biotechnology of Bioactive Compounds. Sources and Applications Новинка

Anthonia O'Donovan Biotechnology of Bioactive Compounds. Sources and Applications

21507.54 руб. или Купить в рассрочку!
Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.
Cossy Janine Modern Tools for the Synthesis of Complex Bioactive Molecules Cossy Janine Modern Tools for the Synthesis of Complex Bioactive Molecules Новинка

Cossy Janine Modern Tools for the Synthesis of Complex Bioactive Molecules

12436.29 руб. или Купить в рассрочку!
All the latest tools needed to plan and perform the synthesis of complex bioactive molecules Focusing on organic, organometallic, and bio-oriented processes, this book explores the impact and use of the latest synthetic tools for the synthesis of complex biologically active compounds. Readers will discover step by step how these synthetic tools have provided new, elegant solutions to many synthetic puzzles. Moreover, they will discover innovative methods that make it possible to control the exact connectivity of atoms within a molecule in order to set precise three-dimensional arrangements. Modern Tools for the Synthesis of Complex Bioactive Molecules features sixteen chapters, each one written by one or more leading experts in organic synthesis from around the world. It covers a broad range of topics that enable readers to take advantage of the latest methods for synthesizing complex molecules, including: Modern catalysis, emphasizing key transformations such as C-H functionalizations, cross-couplings, gold-catalyzed reactions, metathesis-based syntheses, and asymmetric organocatalysis Eco-compatible transformations, including rearrangements and domino reactions Tools for the synthesis of carbohydrates and alkaloids New techniques, including the use of fluorous tags and engineered biosynthesis The last two chapters explore target- and diversity-oriented organic synthesis as well as the use of DNA-based asymmetric catalysis, which are all promising tools for the successful synthesis of complex bioactive molecules. Modern Tools for the Synthesis of Complex Bioactive Molecules is ideal for students and researchers who need to plan and perform the synthesis of complex molecules as efficiently as possible. The book's expert advice will help these readers quickly resolve a broad range of problems that can arise in organic syntheses.
Neelottama Kushwaha, Swatantra K. S. Kushwaha Synthesis of Some Amide Derivatives and Their Biological Activity Neelottama Kushwaha, Swatantra K. S. Kushwaha Synthesis of Some Amide Derivatives and Their Biological Activity Новинка

Neelottama Kushwaha, Swatantra K. S. Kushwaha Synthesis of Some Amide Derivatives and Their Biological Activity

This book has been primarily design for the undergraduate, postgraduate and researchers in pharmaceutical chemistry. In a broader perspective, the students studying pharmaceutical sciences at undergraduate, postgraduate or researchers shall be grossly benefited by it's well planned, systematically developed, structured, illustrated, expanded and elaborated subject matter. It contains all the basic concepts and principles that a researcher should know about the different aspects of the synthesis including the biological activity of the pharmaceutical compounds. This book also provides spectral analysis of newly synthesize compounds. The book is well illustrated. Hopefully it will serve as a key to the undergraduate, postgraduate and researchers in pharmaceutical chemistry.The authors earnestly believe that the wide coverage various synthetic schemes would certainly render pharmaceutical chemistry to serve as an exclusive source of information's, ideas, inspiration towards research and finding newer possible practical solutions to problems encountered in the synthesis of pharmaceutical compounds.
Alain Tressaud Functionalized Inorganic Fluorides. Synthesis, Characterization and Properties of Nanostructured Solids Alain Tressaud Functionalized Inorganic Fluorides. Synthesis, Characterization and Properties of Nanostructured Solids Новинка

Alain Tressaud Functionalized Inorganic Fluorides. Synthesis, Characterization and Properties of Nanostructured Solids

16888.33 руб. или Купить в рассрочку!
Functionalized Inorganic Fluorides: Synthesis, Characterization & Properties of Nanostructured Solids covers several classes of nanostructured and functionalized inorganic fluorides, oxide-fluorides, and fluorinated oxides such as silica and alumina. Ranging from powders or glass-ceramics to thin layers and coatings, they have applications as more efficient and less aggressive catalysts, UV absorbers, planar optical waveguides, integrated lasers and optical amplifiers, luminescent materials, anti-reflective coatings and high Tc superconductors. With a focus on new types of solids, such as nanopowders, hybrids, mesoporous fluorides, and intercalation compounds, the book covers new synthesis routes; physical-chemical characterizations – including morphology, structure, spectroscopic and optical behaviour; detailed ab initio investigations and simulations; and -last but not least- potential applications.
Jorge Carlos Ruiz Ruiz New Polymers for Encapsulation of Nutraceutical Compounds Jorge Carlos Ruiz Ruiz New Polymers for Encapsulation of Nutraceutical Compounds Новинка

Jorge Carlos Ruiz Ruiz New Polymers for Encapsulation of Nutraceutical Compounds

13217.59 руб. или Купить в рассрочку!
The incorporation of functional ingredients in a given food system and the processing and handling of such foods are associated with nutritional challenges for their healthy delivery. The extreme sensitivity of some components cause significant loss of product quality, stability, nutritional value and bioavailability, and the overall acceptability of the food product. Consequently, encapsulation has been successfully used to improve stability and bioavailability of functional ingredients. Encapsulation is one example of technology that has the potential to meet the challenge of successfully incorporating and delivering functional ingredients into a range of food types. The book will cover topics about 1) Characterization of novel polymers and their use in encapsulation processes. 2) Stability of nutraceutical compounds encapsulated with novel polymers. 3) Application of encapsulated compounds with novel polymers in functional food systems. This book provides a detailed overview of technologies for preparing and characterisation of encapsulates for food active ingredients using modified polymers. The use of modified polymers as coating materials it is a field that still needs study. The book is aimed to inform students and researchers in the areas of food science and food technology, and professionals in the food industry.
Manfred Schlosser Organometallics in Synthesis, Third Manual Manfred Schlosser Organometallics in Synthesis, Third Manual Новинка

Manfred Schlosser Organometallics in Synthesis, Third Manual

10027.44 руб. или Купить в рассрочку!
WINNER of the 2013 PROSE Award in Chemistry & Physics This latest edition enables readers to master new classes of organometallic compounds and syntheses A popular resource used by synthetic organic chemists around the world, this book enables readers to conduct seamless synthetic reactions involving key organometallics. Each reaction is set forth in the book's acclaimed recipe-style format so that readers can easily replicate the results in their own labs. Moreover, each chapter has been written by a world leader in the field of organometallics in organic synthesis. These authors offer hands-on guidance and practical examples illustrating the preparation of organometallics and its application in organic synthesis. This Third Manual of Organometallics in Synthesis features completely new content and topics, with an eye towards providing researchers with the most useful and practical reference on the synthesis of organometallics. Organized into chapters by type of organometallic compound, the book covers: Organoalkali chemistry Organomagnesium and organozinc chemistry Organosilicon and relating organotin chemistry Organoiron chemistry Organopalladium chemistry Within each chapter, readers will find background information to learn more about the class of organometallics as well as mechanistic considerations. The authors thoroughly discuss the various methods of preparing the organometallic compounds presented in the book and outline their uses in synthetic reactions. In addition to current applications, the authors explore future research opportunities for each organometallic class. References at the end of each chapter enable readers to explore all the topics in greater depth. More and more industrial processes rely on organometallic chemistry. As a result, readers will find this book's step-by-step instructions essential in such fields as natural product synthesis, pharmaceuticals, fine chemicals, biotechnology, polymers, and materials science.
Hua-Jie Zhu Organic Stereochemistry. Experimental and Computational Methods Hua-Jie Zhu Organic Stereochemistry. Experimental and Computational Methods Новинка

Hua-Jie Zhu Organic Stereochemistry. Experimental and Computational Methods

10167.38 руб. или Купить в рассрочку!
Adopting a novel approach to the topic by combining theoretical knowledge and practical results, this book presents the most popular and useful computational and experimental methods applied for studying the stereochemistry of chemical reactions and compounds. The text is clearly divided into three sections on fundamentals, spectroscopic and computational techniques, and applications in organic synthesis. The first part provides a brief introduction to the field of chirality and stereochemistry, while the second part covers the different methodologies, such as optical rotation, electronic circular dichroism, vibrational circular dicroism, and Raman spectroscopy. The third section then goes on to describe selective examples in organic synthesis, classified by reaction type, i.e. enantioselective, chemoselective and stereoselective reactions. A final chapter on total synthesis of natural products rounds off the book. A valuable reference for researchers in academia and industry working in the field of organic synthesis, computational chemistry, spectroscopy or medicinal chemistry.
Daniel Lednicer Antineoplastic Drugs. Organic Syntheses Daniel Lednicer Antineoplastic Drugs. Organic Syntheses Новинка

Daniel Lednicer Antineoplastic Drugs. Organic Syntheses

10047.35 руб. или Купить в рассрочку!
The past decade has seen a significant increase of research aimed at discovering new drugs for treating cancer, and the increasing number of new antineoplastic drugs approved by regulatory agencies reflects this. Until now, details on the synthesis of these newer agents have been scattered in various journals and in US and European patents. This timely volume deals with the organic chemistry involved in the synthesis of the agents found within antineoplastic drugs, including descriptions of the synthetic schemes for the preparation of over 200 compounds that have been granted non-proprietary names. Compounds are collected in chapters based on the mechanism of action rather than on their chemical structures. Each individual chapter is preceded by a brief description of that mechanism and includes detailed flow charts of the preparation of those compounds accompanied by discussions of the organic chemistry involved in each step. The first half of this volume is dedicated to the syntheses of established chemotherapy drugs. Kinase inhibitors occupy the following chapters with the largest single chapter dealing with the fifty compounds that inhibit tyrosine kinase. This class stands out since over twenty compounds in this group have been approved for treating patients; a rare track record compared to any other class of therapeutic agents. Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations. The book is accessible to advanced undergraduates as well as graduates and researchers as well as those with a thorough grasp of organic chemistry.
Patel Paresh N., Patel Yogesh S., Dodiya Dipti K. Transition metal based organometal compounds. antimicrobial agent Patel Paresh N., Patel Yogesh S., Dodiya Dipti K. Transition metal based organometal compounds. antimicrobial agent Новинка

Patel Paresh N., Patel Yogesh S., Dodiya Dipti K. Transition metal based organometal compounds. antimicrobial agent

The development of bioactive organometallic compound is one of the biggest achievements made in chemistry which has a significant effect on everyday life. Remarkable improvement in humanity's progress has been observed from the "Hydrocarbons" to the "Allylic compounds" to the "Aryl compounds" to the "Organometallic compound". "Organometallic compound" is now a household word. Organometallic compound derived from transition metal ions are defined as hybrid substances which are composed of metal ions or clusters connected by poly topic organic linkers via strong coordination bonds. Organometallic compound sometimes referred to as metal-organic frameworks (MOFs) or organometallic compounds. In recent years, the design and construction of organometallic compound have attracted increasing attention. The aim of this book is to provide a brief knowledge about Organometallic compound. We have included the synthesis of various novel organic ligands and their metal complexes and their characterization by various spectroscopic and thermal techniques.
Rosaleen Anderson Antibacterial Agents. Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications Rosaleen Anderson Antibacterial Agents. Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications Новинка

Rosaleen Anderson Antibacterial Agents. Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications

13544.5 руб. или Купить в рассрочку!
Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA – quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes – sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis – aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis – β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.
Kandregula Ganapathi Rao, Venkateswara Rao K, Ashok CH Self-Cleaning Application of Nanoporous Materials Kandregula Ganapathi Rao, Venkateswara Rao K, Ashok CH Self-Cleaning Application of Nanoporous Materials Новинка

Kandregula Ganapathi Rao, Venkateswara Rao K, Ashok CH Self-Cleaning Application of Nanoporous Materials

Metal oxide nanoparticles are chemically very stable compounds; hence they can be used for the vast number of applications. TiO2 nano material having hydrophobic nature, non-wettability, non-toxicity, it can be used for the self-cleaning coating of ceramics, glass and sports equipments, whereas MgO nano materials shows the good anti-bacterial activity. In the project synthesis of metal oxide using to two different techniques called "Co-Precipitation" and "Green Synthesis", and compare the results using appropriate characterization. Extract of Lotus Leaves was used as reducing agent instead of NaOH in Green synthesis method. The obtained nano materials were characterized using XRD, PSA, FESEM, EDAX, TEM, FTIR, UV-VISIBLE and TG-DTA. The material applications were studied not only for self-cleaning nature using contact angle but also for anti-bacterial activity.
Stephen Liddle T. Molecular Metal-Metal Bonds. Compounds, Synthesis, Properties Stephen Liddle T. Molecular Metal-Metal Bonds. Compounds, Synthesis, Properties Новинка

Stephen Liddle T. Molecular Metal-Metal Bonds. Compounds, Synthesis, Properties

2107.27 руб. или Купить в рассрочку!
Systematically covering all the latest developments in the field, this is a comprehensive and handy introduction to metal-metal bonding. The chapters follow a uniform, coherent structure for a clear overview, allowing readers easy access to the information. The text covers such topics as synthesis, properties, structures, notable features, reactivity and examples of applications of the most important compounds in each group with metal-metal bonding throughout the periodic table. With its general remarks at the beginning of each chapter, this is a must-have reference for all molecular inorganic chemists, including PhD students and postdocs, as well as more experienced researchers.
Iwao Ojima Catalytic Asymmetric Synthesis Iwao Ojima Catalytic Asymmetric Synthesis Новинка

Iwao Ojima Catalytic Asymmetric Synthesis

16884.56 руб. или Купить в рассрочку!
Praise for the previous editions «An excellent text . . . will no doubt provide the benchmark for comparative works for many years.» —Journal of the American Chemical Society «An excellent state-of-the-art compilation of catalytic asymmetric chemistry . . . should be included in any chemistry reference collection.» —Choice «This is a tremendous resource and an excellent read. I recommend immediate purchase.» —Perkin Transactions Since this important work was first published in 1993, the field of catalytic asymmetric synthesis has grown explosively, spawning effective new methods for obtaining enantiomerically pure compounds on a large scale and stimulating new applications in diverse fields—from medicine to materials science. Catalytic Asymmetric Synthesis, Third Edition addresses these rapid changes through contributions from highly recognized world leaders in the field. This seminal text presents detailed accounts of the most important catalytic asymmetric reactions known today, and discusses recent advances and essential information on the initial development of certain processes. An excellent working resource for academic researchers and industrial chemists alike, the Third Edition features: Six entirely new chapters focusing on novel approaches to catalytic asymmetric synthesis including non-conventional media/conditions, organocatalysis, chiral Lewis and Bronsted acids, CH activation, carbon-heteroatom bond-forming reactions, and enzyme-catalyzed asymmetric synthesis A new section focusing on the important new reaction, asymmetric metathesis, in carbon-carbon bond-forming reactions Updated chapters on hydrogenation, carbon-carbon bond-forming reactions, hydrosilylations, carbonylations, oxidations, amplifications and autocatalysis, and polymerization reactions Retaining the best of its predecessors but now thoroughly up to date, Catalytic Asymmetric Synthesis, Third Edition serves as an excellent desktop reference and text for researchers and students from the upper-level undergraduates through experienced professionals in industry or academia.
JOSÉ MARCO-CONTELLES, Maria do Carmo Carreiras New Classical Propargylic Rearrangements in Natural Products Synthesis JOSÉ MARCO-CONTELLES, Maria do Carmo Carreiras New Classical Propargylic Rearrangements in Natural Products Synthesis Новинка

JOSÉ MARCO-CONTELLES, Maria do Carmo Carreiras New Classical Propargylic Rearrangements in Natural Products Synthesis

In this book we highlight the strong synthetic potential and scope of transition metal-catalyzed rearrangement reactions for fully economical and complex carbon-carbon bond forming reactions. The Meyer-Schuster and the Rupe rearrangements are emerging as the methods of choice for the homologation of carbonyl compounds into α,β-unsaturated aldehydes and ketones, particularly useful for the synthesis of many hindered ketones. The Rautenstrauch-I and Rautenstrauch-II rearrangements of readily propargylic derivatives are very useful reactions for the synthesis of complex cyclopentenones, and bicyclo[n.1.0] enol carboxylates in high chemical yields, which proceed under mild reaction conditions with high stereoselectivity, and total transfer of chirality. In the case of Rautenstrauch-II, the basic-methanolysis of the resulting compounds provides bicyclo[n.1.0]ketones, valuable building blocks for the preparation of natural products. A reaction mechanism has been advanced, and confirmed by experimental evidences, which supports the involvement of metallo-carbenes as key species formed through a cyclopropanation event that precedes the 1,2-acyloxy migration.
Viktor Zhdankin V. Hypervalent Iodine Chemistry. Preparation, Structure, and Synthetic Applications of Polyvalent Iodine Compounds Viktor Zhdankin V. Hypervalent Iodine Chemistry. Preparation, Structure, and Synthetic Applications of Polyvalent Iodine Compounds Новинка

Viktor Zhdankin V. Hypervalent Iodine Chemistry. Preparation, Structure, and Synthetic Applications of Polyvalent Iodine Compounds

13544.5 руб. или Купить в рассрочку!
Hypervalent Iodine Chemistry is the first comprehensive text covering all of the main aspects of the chemistry of organic and inorganic polyvalent iodine compounds, including applications in chemical research, medicine, and industry. Providing a comprehensive overview of the preparation, properties, and synthetic applications of this important class of reagents, the text is presented in the following way: The introductory chapter provides a historical background and describes the general classification of iodine compounds, nomenclature, hypervalent bonding, structural features, and the principles of reactivity of polyvalent iodine compounds. Chapter 2 gives a detailed description of the preparative methods and structural features of all known classes of organic and inorganic derivatives of polyvalent iodine. Chapter 3, the key chapter of the book, deals with the many applications of hypervalent iodine reagents in organic synthesis. Chapter 4 describes the most recent achievements in hypervalent iodine catalysis. Chapter 5 deals with recyclable polymer-supported and nonpolymeric hypervalent iodine reagents. Chapter 6 covers the «green» reactions of hypervalent iodine reagents under solvent-free conditions or in aqueous solutions. The final chapter provides an overview of the important practical applications of polyvalent iodine compounds in medicine and industry. This book is aimed at all chemists interested in iodine compounds, including academic and industrial researchers in inorganic, organic, physical, medicinal, and biological chemistry. It will be particularly useful to synthetic organic and inorganic chemists, including graduate and advanced undergraduate students. It comprehensively covers the green chemistry aspects of hypervalent iodine chemistry, making it especially useful for industrial chemists.
Armando Pombeiro J.L. Alkane Functionalization Armando Pombeiro J.L. Alkane Functionalization Новинка

Armando Pombeiro J.L. Alkane Functionalization

20356.47 руб. или Купить в рассрочку!
Presents state-of-the-art information concerning the syntheses of valuable functionalized organic compounds from alkanes, with a focus on simple, mild, and green catalytic processes Alkane Functionalization offers a comprehensive review of the state-of-the-art of catalytic functionalization of alkanes under mild and green conditions. Written by a team of leading experts on the topic, the book examines the latest research developments in the synthesis of valuable functionalized organic compounds from alkanes. The authors describe the various modes of interaction of alkanes with metal centres and examine theoxidative alkane functionalization upon C-O bond formation. They address the many types of mechanisms, discuss typical catalytic systems and highlight the strategies inspired by biological catalytic systems. The book also describes alkane functionalization upon C-heteroatom bond formation as well as oxidative and non-oxidative approaches. In addition, the book explores non-transition metal catalysts and metal-free catalytic systems and presents selected types of functionalization of sp3 C-H bonds pertaining to substrates other than alkanes. This important resource: Presents a guide to the most recent advances concerning the syntheses of valuable functionalized organic compounds from alkanes Contains information from leading experts on the topic Offers information on the catalytic functionalization of alkanes that allows for improved simplicity and sustainability compared to current multi-stage industrial processes Explores the challenges inherent with the application of alkanes as starting materials for syntheses of added value functionalized organic compounds Written for academic researchers and industrial scientists working in the fields of coordination chemistry, organometallic chemistry, catalysis, organic synthesis and green chemistry, Alkane Functionalization is an important resource for accessing the most up-to-date information available in the field of catalytic functionalization of alkanes.
Shahid Ul-Islam Plant-Based Natural Products. Derivatives and Applications Shahid Ul-Islam Plant-Based Natural Products. Derivatives and Applications Новинка

Shahid Ul-Islam Plant-Based Natural Products. Derivatives and Applications

14512.52 руб. или Купить в рассрочку!
Intense research has been started all around the world in the past few decades to exploit different agents from natural products as eco-friendly alternative to synthetic and toxic chemicals. Natural products and their derivatives have received increasing attention for their use in many everyday applications ranging from food, medicine, textiles, and healthcare.This new book presents significant research advances about the use of natural products, mainly plant colorants, bioactive compounds and other plant extracts in the textile coloration, food, bioremediation and environmental applications. There are total eight chapters contributed by leading researchers covering the topics such as potential resurgence of natural dyes in applied fields, natural colorants from indigoid plants, phytochemistry of dye yielding plants, irradiation as novel pretreatment methods, dyeing studies with henna plant, phytoremediation of arsenic, and synthesis of curcumin complexes for medicinal and other industrial uses.
Gary Pickrell Processing and Properties of Advanced Ceramics and Composites V Gary Pickrell Processing and Properties of Advanced Ceramics and Composites V Новинка

Gary Pickrell Processing and Properties of Advanced Ceramics and Composites V

9897.66 руб. или Купить в рассрочку!
Contains contributed 38 papers from the following seven symposia held during the 2012 Materials Science and Technology (MS&T’12) meeting: Innovative Processing and Synthesis of Ceramics, Glasses and Composites Advances in Ceramic Matrix Composites Solution Based Processing for Ceramic Materials Novel Sintering Processes and News in the Conventional Sintering and Grain Growth Nanotechnology for Energy, Healthcare and Industry Dielectric Ceramic Materials and Electronic Devices Controlled Synthesis, Processing, and Applications of Structure and Functional Nanomaterials
Suresh Kumar Venugopal, Nithya Ranganathan, Narendhar Chandrasekar Green Synthesis of Silver Nanoparticles Usim Triticum Aestivum and Emblica Officinalis. Characterization and their Antibacterial Study Suresh Kumar Venugopal, Nithya Ranganathan, Narendhar Chandrasekar Green Synthesis of Silver Nanoparticles Usim Triticum Aestivum and Emblica Officinalis. Characterization and their Antibacterial Study Новинка

Suresh Kumar Venugopal, Nithya Ranganathan, Narendhar Chandrasekar Green Synthesis of Silver Nanoparticles Usim Triticum Aestivum and Emblica Officinalis. Characterization and their Antibacterial Study

Master's Thesis from the year 2016 in the subject Biology - Micro- and Molecular Biology, Bharathiar University, course: Biotechnology, language: English, abstract: The object of the work was to extract the compounds from Triticum aestivum & Emblica officinalis for Silver Nanoparticle Synthesis and characterize the synthesized silver nanoparticles using UV-VIS, SEM & DLS. Identifying the compound responsible for nanoparticle synthesis using FTIR and anti-microbial action. Study the anti-microbial activity of the synthesized silver nanoparticles and comparison with crude extract.
Oleg Kulinkovich G. Cyclopropanes in Organic Synthesis Oleg Kulinkovich G. Cyclopropanes in Organic Synthesis Новинка

Oleg Kulinkovich G. Cyclopropanes in Organic Synthesis

13023.42 руб. или Купить в рассрочку!
This is a practical guidebook about cyclopropanes that thoroughly surveys derivatives and transformations, synthetic methods, and experimental efficiency as a gateway for further research and development in the field. • Provides comprehensive lists and synthetically-oriented synopses of cyclopropane chemistry review references along with publication data on applications in the syntheses of natural and related biologically active compounds • Acts as a resource to help readers better understand cyclopropane applications for the efficient realization of synthetically important organic transformations and popular experimental procedures • Includes new developments and up-to-date information that will lead to original methodologies for complex organic synthesis • Stresses universality, flexibility, and experimental efficiency of a strategy based on preparing cyclopropane derivatives and performing ring cleavage reactions with inexpensive reagents • Focuses on the synthetic potential of cyclopropane applications, for example the synthesis of natural compounds and other target-oriented syntheses via cyclopropane intermediaries, as well on their planning by retrosynthetic analysis

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One approach to organic synthesis is retrosynthetic analysis. With this approach chemists start with the structures of their target molecules and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Workbook for Organic Synthesis: The Disconnection Approach, 2nd Edition This workbook provides a comprehensive graded set of problems to illustrate and develop the themes of each of the chapters in the textbook Organic Synthesis: The Disconnection Approach, 2nd Edition. Each problem is followed by a fully explained solution and discussion. The examples extend the student’s experience of the types of molecules being synthesised by organic chemists, and the strategies they employ to control their syntheses. By working through these examples students will develop their skills in analysing synthetic challenges, and build a toolkit of strategies for planning new syntheses. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. Together the workbook and textbook provide a complete course in retrosynthetic analysis. Organic Synthesis: The Disconnection Approach, 2nd Edition There are forty chapters in Organic Synthesis: The Disconnection Approach, 2nd Edition: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. In its second edition updated examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, Organic Synthesis: Strategy and Control. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Workbook for Organic Synthesis: The Disconnection Approach, 2nd edition, combined with the main textbook, provides a full course in retrosynthetic analysis for chemistry and biochemistry students, and a refresher course for organic chemists working in industry and academia.
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