the role of dccbs in the agricultural development of india

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Patrizia Lombardi Future Challenges in Evaluating and Managing Sustainable Development in the Built Environment Patrizia Lombardi Future Challenges in Evaluating and Managing Sustainable Development in the Built Environment
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Patrizia Lombardi Future Challenges in Evaluating and Managing Sustainable Development in the Built Environment


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11248.25 руб.

Future Challenges in Sustainable Development within the Built Environment stimulates and reinterprets the demands of Responsible and Sustainable Development in the Built Environment for future action and development. It examines the methods of evaluation, the use of technology, the creation of new models and the role of human factors for examining and developing the subject over the next twenty years.

Jan Pronk P. Catalysing Development? A Debate on Aid Jan Pronk P. Catalysing Development? A Debate on Aid
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Jan Pronk P. Catalysing Development? A Debate on Aid


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2174.26 руб.

This volume presents a state-of-the-art debate on the controversial topic of development aid. The contributors are all experts in the field of international development. Presents some challenging conclusions about the role that aid plays in catalysing, or stifling, development. Represents a wide range of different analytical perspectives.

Danil Dzha Adventures of Indi, the Little Princess. Part 1 «Yoly» Danil Dzha Adventures of Indi, the Little Princess. Part 1 «Yoly»
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Danil Dzha Adventures of Indi, the Little Princess. Part 1 «Yoly»


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20 руб.

The events of this story unfold in India in the middle ages. A little Princess from a noble Kingdom is kidnapped by a mysterious forest creature. Her father, King Raja, and his faithful commander Sikh go in search of her. Impassable jungles, mangroves, mountain rivers, wild animals and magic await them on the way to the mysterious Spruce Forest. In the role of antagonists are the well-known archetypes of Slavic mythology, the history of which, according to one version, began in India.

Michael E. Lamb The Role of the Father in Child Development Michael E. Lamb The Role of the Father in Child Development
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Michael E. Lamb The Role of the Father in Child Development


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8248.71 руб.

The Definitive reference on the important role fathers play in child development today Edited by Dr. Michael Lamb—the recognized authority on the role of fathers in child development, The Role of the Father in Child Development, Fifth Edition brings together contributions from international experts on each subject to provide a thorough and current summary of the state of fatherhood across cultures, classes, economic systems, and family formations. This classic guide offers a single-source reference for the most recent findings and beliefs related to fathers and fatherhood. This thoroughly updated new edition provides the latest material on topics such as: The effects of divorce Fathers from low-income backgrounds Stepfathers’ lives: exploring social context and interpersonal complexity Social policy Gay fathers Fatherhood and masculinity The definitive book on when, why, and how fathers matter to their children and families, The Role of the Father in Child Development, Fifth Edition is an essential reference for all mental health professionals who endeavor to understand and support fathers in becoming positive influences in their children’s development.

Michael E. Lamb The Role of the Father in Child Development Michael E. Lamb The Role of the Father in Child Development
:

Michael E. Lamb The Role of the Father in Child Development


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8557.02 руб.

The Definitive reference on the important role fathers play in child development today Edited by Dr. Michael Lamb—the recognized authority on the role of fathers in child development, The Role of the Father in Child Development, Fifth Edition brings together contributions from international experts on each subject to provide a thorough and current summary of the state of fatherhood across cultures, classes, economic systems, and family formations. This classic guide offers a single-source reference for the most recent findings and beliefs related to fathers and fatherhood. This thoroughly updated new edition provides the latest material on topics such as: The effects of divorce Fathers from low-income backgrounds Stepfathers’ lives: exploring social context and interpersonal complexity Social policy Gay fathers Fatherhood and masculinity The definitive book on when, why, and how fathers matter to their children and families, The Role of the Father in Child Development, Fifth Edition is an essential reference for all mental health professionals who endeavor to understand and support fathers in becoming positive influences in their children’s development.

Peter Blythe Attention, Balance and Coordination. The A.B.C. of Learning Success Peter Blythe Attention, Balance and Coordination. The A.B.C. of Learning Success
:

Peter Blythe Attention, Balance and Coordination. The A.B.C. of Learning Success


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4354.16 руб.

An updated edition of the definitive handbook on the physical basis for learning for professionals involved in education and child development, written by the respected author of acclaimed titles in the field. A comprehensive overview of the relationship between neuromotor maturity and physical development on learning outcomes and behaviour in childhood and later life Explores why early reflexes are important, their functions in early development, their effects on learning and behavior if retained, and the possible effects on other aspects of development Brings together a specialist body of knowledge and makes it accessible to anyone involved in treating the symptoms of specific learning difficulties and emotional problems. Includes new information on the role of the vestibular system in anxiety and agoraphobia, a new chapter of case studies, and an Epilogue placing the INPP Method in a broader scientific context

Peter Hedden Annual Plant Reviews, The Gibberellins Peter Hedden Annual Plant Reviews, The Gibberellins
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Peter Hedden Annual Plant Reviews, The Gibberellins


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15743.99 руб.

First discovered as fungal metabolites, the gibberellins were recognised as plant hormones over 50 years ago. They regulate reproductive development in all vascular plants, while their role in flowering plants has broadened to include also the regulation of growth and other developmental processes. This timely book covers the substantial and impressive recent advances in our understanding of the gibberellins and their roles in plant development, including the biosynthesis, inactivation, transport, perception and signal transduction of these important hormones. An introductory chapter traces the history of gibberellin research, describing the many discoveries that form the basis for the recent progress. The exciting emerging evidence for the interaction of gibberellin signalling with that of the other hormones is critically evaluated. The occurrence of gibberellins in fungal, bacterial and lower plant species is also discussed, with emphasis on evolution. Manipulation of gibberellin metabolism and signal transduction through chemical or genetic intervention has been an important aspect of crop husbandry for many years. The reader is presented with important information on the advances in applying gibberellin research in agriculture and horticulture. Annual Plant Reviews, Volume 49: The Gibberellins is an important resource for plant geneticists and biochemists, as well as agricultural and horticultural research workers, advanced students of plant science and university lecturers in related disciplines. It is an essential addition to the shelves of university and research institute libraries and agricultural and horticultural institutions teaching and researching plant science.

India THE CONSTITUTION OF INDIA India THE CONSTITUTION OF INDIA
:

India THE CONSTITUTION OF INDIA


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33 руб.

This is the third pocket size edition of the Constitution of India in the diglot form. In this edition, the text of the Constitution of India has been brought up-to-date by incorporating therein all the amendments up to and including the Constitution (Ninety-Sixth Amendment) Act, 2011.

Michael Maratsos Minnesota Symposium on Child Psychology, Volume 38. Culture and Developmental Systems Michael Maratsos Minnesota Symposium on Child Psychology, Volume 38. Culture and Developmental Systems
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Michael Maratsos Minnesota Symposium on Child Psychology, Volume 38. Culture and Developmental Systems


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10873.3 руб.

The latest on child psychology and the role of cultural and developmental systems Now in its 38th volume, Minnesota Symposia on Child Psychology: Culture and Developmental Systems contains the collected papers from the most prestigious symposia in the field of child development. Providing scholars, students, and practitioners with access to the work of leading researchers in human development, it outlines how the field has advanced dramatically in recent years—both empirically and conceptually. The updated collection outlines the latest information and research on child psychology, including the cultural neuroscience of the developing brain in childhood, the role of culture and language in the development of color categorization, socioemotional development across cultures, and much more. Find out how much math is 'hard wired,' if at all Explore the development of culture, language, and emotion Discover cultural expressions and the neurobiological underpinnings in mother-infant interactions Examine the cultural organization of young children's everyday learning Written for generalists and specialists alike, Minnesota Symposia on Child Psychology offers the most up-to-date information on the central processes of human development and its implications for school success, as well as other areas.

Jean-Paul Caltagirone Discrete Mechanics Jean-Paul Caltagirone Discrete Mechanics
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Jean-Paul Caltagirone Discrete Mechanics


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10048.72 руб.

This book presents the fundamental principles of mechanics to re-establish the equations of Discrete Mechanics. It introduces physics and thermodynamics associated to the physical modeling. The development and the complementarity of sciences lead to review today the old concepts that were the basis for the development of continuum mechanics. The differential geometry is used to review the conservation laws of mechanics. For instance, this formalism requires a different location of vector and scalar quantities in space. The equations of Discrete Mechanics form a system of equations where the Helmholtz-Hodge decomposition plays an important role.

Maxim Kitaev New England. Alternative history Maxim Kitaev New England. Alternative history
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Maxim Kitaev New England. Alternative history


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48 руб.

It is known that Columbus visited England in 1477. At the time, he was looking for a funding of his expedition to the shore of India. How will the development of world history progress if Henry VII helps Columbus to organize his first trip in 1986?

Teeuwen Mark A New History of Shinto Teeuwen Mark A New History of Shinto
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Teeuwen Mark A New History of Shinto


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8553.13 руб.

This accessible guide to the development of Japan’s indigenous religion from ancient times to the present day offers an illuminating introduction to the myths, sites and rituals of kami worship, and their role in Shinto’s enduring religious identity. Offers a unique new approach to Shinto history that combines critical analysis with original research Examines key evolutionary moments in the long history of Shinto, including the Meiji Revolution of 1868, and provides the first critical history in English or Japanese of the Hie shrine, one of the most important in all Japan Traces the development of various shrines, myths, and rituals through history as uniquely diverse phenomena, exploring how and when they merged into the modern notion of Shinto that exists in Japan today Challenges the historic stereotype of Shinto as the unchanging, all-defining core of Japanese culture

Alexei Verkhratsky Glial Physiology and Pathophysiology Alexei Verkhratsky Glial Physiology and Pathophysiology
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Alexei Verkhratsky Glial Physiology and Pathophysiology


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12369.51 руб.

Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverae includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases – for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role og glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides

Helyette Geman Agricultural Finance. From Crops to Land, Water and Infrastructure Helyette Geman Agricultural Finance. From Crops to Land, Water and Infrastructure
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Helyette Geman Agricultural Finance. From Crops to Land, Water and Infrastructure


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7454.98 руб.

A comprehensive resource for understanding the complexities of agricultural finance Agricultural Finance: From Crops to Land, Water, and Infrastructure is a pioneering book that offers a comprehensive resource for understanding the worldwide agriculture markets, from spikes in agricultural commodity prices to trading strategies, and the agribusiness industry generally to the challenges of feeding the planet in particular. The book also goes in-depth on the topics of land, water, fertilizers, biofuels, and ethanol. Written by Helyette Geman—an industry expert in commodity derivatives—this book explores the agricultural marketplace and the cycles in agricultural commodity prices that can be the key to investor success. This resource addresses a wide range of other important topics as well, including agricultural insurance, energy, shipping and bunker prices, sustainability, investments in land, subsidies, agricultural derivatives, and farming risk-management. Other topics covered include structured products and agricultural commodities ETFs; trade finance in an era of credit shortage; securitization and commodity-linked notes; grains: wheat, corn, soybeans; softs: coffee, cocoa, cotton; shipping as a key component of agricultural trade; and the major agricultural shipping routes and the costs. The book: Offers the first comprehensive resource that deals with the all aspects of agricultural finance Includes information that is crucial for pension funds, asset managers, hedge funds, agribusiness corporates, CTAs and regulators Covers a range of topics from agricultural bunker prices, futures, options to major shipping routes and the costs This text is a must-have resource for accessing the information required to trade successfully in the agricultural marketplace.

Natanya Civjan Chemical Biology. Approaches to Drug Discovery and Development to Targeting Disease Natanya Civjan Chemical Biology. Approaches to Drug Discovery and Development to Targeting Disease
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Natanya Civjan Chemical Biology. Approaches to Drug Discovery and Development to Targeting Disease


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10657.38 руб.

An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including: The design, development, and optimization of drug candidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models as pharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV to schizophrenia Chemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences.

Lorenzo Pinna A. Protein Kinase CK2 Lorenzo Pinna A. Protein Kinase CK2
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Lorenzo Pinna A. Protein Kinase CK2


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16254.45 руб.

Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human phosphoproteome. The role CK2 plays in the development of cancer and other disease has also made it of significant interest for its potential role in future therapeutics. Protein Kinase CK2 comprehensively brings together the varied work being done on this critical enzyme. Protein Kinase CK2 is logically divided into three sections. The first section reviews key molecular and structural aspects of the enzyme. The second section looks at functional aspects of CK2 and the diverse roles it plays in cellular development, function, and health. The final section focuses on CK2 and cancer, looking at the impacts of the kinase on neoplastic development and its rapidly developing role as a therapeutic agent. With contributions from the world’s leading experts in the field, Protein Kinase CK2 will serve as an invaluable guide to the expanding and vibrant body of research being performed on this enzyme. This will be an essential volume for anyone working in the fields of biochemistry, protein science, signal transduction, metabolic regulation, and cancer biology and therapeutics. Editor Lorenzo A. Pinna is Professor in the Department of Biomedical Sciences at the University of Padua, Padua, Italy. Also Published in the Wiley-IUBMB Series on Biochemistry and Molecular Biology: Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology Edited by Cesar G. Fraga ISBN: 978-0-470-28721-7

R. Akers Michael Lactation and the Mammary Gland R. Akers Michael Lactation and the Mammary Gland
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R. Akers Michael Lactation and the Mammary Gland


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9144.45 руб.

Michael Akers provides the basics for understanding mammary development and lactation and conveys the critical regulatory events in lactation. This text willl prove to be an invaluable overview of mamorary development and lactation for undergraduates and graduates studying lactation, new researchers, and as a review for established scientists. Additionally, the book will be an important resource for professionals in the animal and dairy industry and for those in other scientific disciplines such as food chemistry, cell biology, and endocrinology whose work is closely tied to mammary gland development and function. Lactation and the Mammary Gland covers growth and development of the mammary gland including comparisons between species. It imparts and emphasizes the critical nature of mammary growth and the onset of lactation at the time of parturition. Special emphasis is given to the endocrine and growth factor regulation of both mammogenesis and lactogenesis. A thorough discussion of the role of growth hormone in development and maintenance of lactation or galactopoiesis adds to this book's value as a text and reference. The author reviews the presence of hormones, growth factors, and other bioactive compounds in milk and mammary secretions as well as the potential for use of the mammary gland as a bioreactor in the pharmaceutical industry. A description of the nutritional and management factors in milk production round out the book's comprehensive coverage.

Randall Moon T. Wnt Signaling in Development and Disease. Molecular Mechanisms and Biological Functions Randall Moon T. Wnt Signaling in Development and Disease. Molecular Mechanisms and Biological Functions
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Randall Moon T. Wnt Signaling in Development and Disease. Molecular Mechanisms and Biological Functions


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13194.81 руб.

Wnt signaling in Development and Disease: Molecular Mechanisms and Biological Functions reviews the core topics in Wnt signaling, from molecular pathway mechanisms to its role in embryogenesis, adult tissue homeostasis, and chronic disease. Written by a team of expert reviewers, the book provides clear and concise coverage of the core foundations of Wnt signaling before advancing to discussion of cutting-edge scientific research. Focused on the biological insights and current scientific questions of Wnt signaling, this book will be a comprehensive and definitive resource for a wide range of researchers and students in cell signaling, cell physiology, developmental biology, and biomedical engineering, as well as anyone interested in learning more about this important and complex protein network. • A definitive source of information on Wnt signaling and its role in development and disease, written by leaders in the field. • Explores the role of Wnt signaling in chronic disease such as melanoma, colorectal cancer, dementia, and psychiatric diseases • Reviews the complex processes of signal integration and regulation • Features broad discussion of Wnt signaling biology as well as detailed discussion of the pathway’s role in diseases and potential clinical applications.

Tama Leventhal Handbook of Child Psychology and Developmental Science, Ecological Settings and Processes Tama Leventhal Handbook of Child Psychology and Developmental Science, Ecological Settings and Processes
:

Tama Leventhal Handbook of Child Psychology and Developmental Science, Ecological Settings and Processes


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17247.31 руб.

The essential reference for human development theory, updated and reconceptualized The Handbook of Child Psychology and Developmental Science, a four-volume reference, is the field-defining work to which all others are compared. First published in 1946, and now in its Seventh Edition, the Handbook has long been considered the definitive guide to the field of developmental science. Volume 4: Ecological Settings and Processes in Developmental Systems is centrally concerned with the people, conditions, and events outside individuals that affect children and their development. To understand children's development it is both necessary and desirable to embrace all of these social and physical contexts. Guided by the relational developmental systems metatheory, the chapters in the volume are ordered them in a manner that begins with the near proximal contexts in which children find themselves and moving through to distal contexts that influence children in equally compelling, if less immediately manifest, ways. The volume emphasizes that the child's environment is complex, multi-dimensional, and structurally organized into interlinked contexts; children actively contribute to their development; the child and the environment are inextricably linked, and contributions of both child and environment are essential to explain or understand development. Understand the role of parents, other family members, peers, and other adults (teachers, coaches, mentors) in a child's development Discover the key neighborhood/community and institutional settings of human development Examine the role of activities, work, and media in child and adolescent development Learn about the role of medicine, law, government, war and disaster, culture, and history in contributing to the processes of human development The scholarship within this volume and, as well, across the four volumes of this edition, illustrate that developmental science is in the midst of a very exciting period. There is a paradigm shift that involves increasingly greater understanding of how to describe, explain, and optimize the course of human life for diverse individuals living within diverse contexts. This Handbook is the definitive reference for educators, policy-makers, researchers, students, and practitioners in human development, psychology, sociology, anthropology, and neuroscience.

Mountstuart Elphinstone An account of the Kingdom of Caubul and its dependencies in Persia, Tartary, and India. Vol. 1 Mountstuart Elphinstone An account of the Kingdom of Caubul and its dependencies in Persia, Tartary, and India. Vol. 1
:

Mountstuart Elphinstone An account of the Kingdom of Caubul and its dependencies in Persia, Tartary, and India. Vol. 1


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0 руб.

Полный вариант заголовка: «An account of the Kingdom of Caubul and its dependencies in Persia, Tartary, and India : Vol. 1 : comprising a view of the Afghaun nation, and a history of the Dooraunee Monarchy : with an entirely new map : in 2 volumes / by the Hon. Mountstuart Elphinstone».

Stewart Kathlyn Human Brain Evolution. The Influence of Freshwater and Marine Food Resources Stewart Kathlyn Human Brain Evolution. The Influence of Freshwater and Marine Food Resources
:

Stewart Kathlyn Human Brain Evolution. The Influence of Freshwater and Marine Food Resources


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12831.64 руб.

The evolution of the human brain and cognitive ability is one of the central themes of physical/biological anthropology. This book discusses the emergence of human cognition at a conceptual level, describing it as a process of long adaptive stasis interrupted by short periods of cognitive advance. These advances were not linear and directed, but were acquired indirectly as part of changing human behaviors, in other words through the process of exaptation (acquisition of a function for which it was not originally selected). Based on studies of the modem human brain, certain prerequisites were needed for the development of the early brain and associated cognitive advances. This book documents the energy and nutrient constraints of the modern brain, highlighting the significant role of long-chain polyunsaturated fatty acids (LC-PUFA) in brain development and maintenance. Crawford provides further emphasis for the role of essential fatty acids, in particular DHA, in brain development, by discussing the evolution of the eye and neural systems. This is an ideal book for Graduate students, post docs, research scientists in Physical/Biological Anthropology, Human Biology, Archaeology, Nutrition, Cognitive Science, Neurosciences. It is also an excellent selection for a grad student discussion seminar.

Mountstuart Elphinstone An account of the Kingdom of Caubul and its dependencies in Persia, Tartary, and India. Vol. 2 Mountstuart Elphinstone An account of the Kingdom of Caubul and its dependencies in Persia, Tartary, and India. Vol. 2
:

Mountstuart Elphinstone An account of the Kingdom of Caubul and its dependencies in Persia, Tartary, and India. Vol. 2


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0 руб.

Полный вариант заголовка: «An account of the Kingdom of Caubul and its dependencies in Persia, Tartary, and India : Vol. 2 : comprising a view of the Afghaun nation, and a history of the Dooraunee Monarchy : with an entirely new map : in 2 volumes / by the Hon. Mountstuart Elphinstone».

Marion Werner Global Displacements. The Making of Uneven Development in the Caribbean Marion Werner Global Displacements. The Making of Uneven Development in the Caribbean
:

Marion Werner Global Displacements. The Making of Uneven Development in the Caribbean


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7120.33 руб.

Challenging the main ways we debate globalization, Global Displacements reveals how uneven geographies of capitalist development shape—and are shaped by—the aspirations and everyday struggles of people in the global South. Makes an original contribution to the study of globalization by bringing together critical development and feminist theoretical approaches Opens up new avenues for the analysis of global production as a long-term development strategy Contributes novel theoretical insights drawn from the everyday experiences of disinvestment and precarious work on people’s lives and their communities Represents the first analysis of increasing uneven development among countries in the Caribbean Calls for more rigorous studies of long accepted notions of the geographies of inequality and poverty in the global South

Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena
:

Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena


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10890.75 руб.

A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs and robotics and other emerging methodologies for LBAs. Highlights include: A general discussion of challenges and proven approaches in the development of ligand-binding assays More detailed examination of characteristics of these assays when applied to support of pharmacokinetic and toxicokinetic studies of compounds at different stages in the discovery or development timeline A concise, but detailed, discussion of validation of ligand-binding assays for macromolecules A practical approach to «fit-for-purpose» validation of assays for biomarkers, those molecules receiving increased attention as potentially demonstrating that the target chosen in discovery is being modulated by the candidate therapeutic, both in nonclinical and clinical studies Written by a team of world-recognized authorities in the field, Ligand-Binding Assays provides key information to a broad range of practitioners, both in the pharmaceutical and allied industries and in related contract research organizations and academic laboratories and, perhaps, even in the field of diagnostics and clinical chemistry.


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The essential reference for human development theory, updated and reconceptualized The Handbook of Child Psychology and Developmental Science, a four-volume reference, is the field-defining work to which all others are compared. First published in 1946, and now in its Seventh Edition, the Handbook has long been considered the definitive guide to the field of developmental science. Volume 4: Ecological Settings and Processes in Developmental Systems is centrally concerned with the people, conditions, and events outside individuals that affect children and their development. To understand children's development it is both necessary and desirable to embrace all of these social and physical contexts. Guided by the relational developmental systems metatheory, the chapters in the volume are ordered them in a manner that begins with the near proximal contexts in which children find themselves and moving through to distal contexts that influence children in equally compelling, if less immediately manifest, ways. The volume emphasizes that the child's environment is complex, multi-dimensional, and structurally organized into interlinked contexts; children actively contribute to their development; the child and the environment are inextricably linked, and contributions of both child and environment are essential to explain or understand development. Understand the role of parents, other family members, peers, and other adults (teachers, coaches, mentors) in a child's development Discover the key neighborhood/community and institutional settings of human development Examine the role of activities, work, and media in child and adolescent development Learn about the role of medicine, law, government, war and disaster, culture, and history in contributing to the processes of human development The scholarship within this volume and, as well, across the four volumes of this edition, illustrate that developmental science is in the midst of a very exciting period. There is a paradigm shift that involves increasingly greater understanding of how to describe, explain, and optimize the course of human life for diverse individuals living within diverse contexts. This Handbook is the definitive reference for educators, policy-makers, researchers, students, and practitioners in human development, psychology, sociology, anthropology, and neuroscience.
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