transdermal delivery of lidocaine prilocaine



Ryan Donnelly F. Microneedle-mediated Transdermal and Intradermal Drug Delivery Ryan Donnelly F. Microneedle-mediated Transdermal and Intradermal Drug Delivery Новинка

Ryan Donnelly F. Microneedle-mediated Transdermal and Intradermal Drug Delivery

11958.73 руб.
Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transdermal and intradermal delivery research using microneedles and includes the outcomes of in vivo animal and human studies. Importantly, it also discusses the safety and patient acceptability studies carried out to date. Finally, the book reviews the recent patents in microneedle research and describes the ongoing developments within industry that will determine the future of microneedle-mediated transdermal and intradermal drug delivery. By an expert author team with practical experience in the design and development of drug delivery systems this is the only text that provides a comprehensive review of microneedle research in transdermal and intradermal drug delivery.
Ryan Donnelly F. Novel Delivery Systems for Transdermal and Intradermal Drug Delivery Ryan Donnelly F. Novel Delivery Systems for Transdermal and Intradermal Drug Delivery Новинка

Ryan Donnelly F. Novel Delivery Systems for Transdermal and Intradermal Drug Delivery

11190.63 руб.
This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.
Benson Heather A.E. Topical and Transdermal Drug Delivery. Principles and Practice Benson Heather A.E. Topical and Transdermal Drug Delivery. Principles and Practice Новинка

Benson Heather A.E. Topical and Transdermal Drug Delivery. Principles and Practice

11483.32 руб.
Practical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors' firsthand experience. Moreover, the book emphasizes the mechanistic information that is essential for successful drug product development. Topical and Transdermal Drug Delivery: Principles and Practice is divided into two parts: Part One, Current Science, Skin Permeation, and Enhancement Approaches, offers readers a fundamental understanding of the underlying science in the field. It describes the principles and techniques needed to successfully perform experimental approaches, covering such issues as skin permeation, enhancement, and assessment. Part Two, Topical and Transdermal Product Development, guides readers through the complete product development process from concept to approval, offering practical tips and cautions from experts in the field. This part also discusses regulations that are specific to the development of dermal drug products. The final chapter explores current and future trends, forecasting new development techniques and therapeutics. Throughout the book, the authors clearly set forth the basic science and experimental procedures, making it possible for researchers to design their own experimental approaches and accurately interpret their results. With contributions from experienced drug researchers, this text is highly recommended for all researchers involved in topical and transdermal product development who need to know both the state of the science and the standards of practice.
Kun Cheng Advanced Drug Delivery Kun Cheng Advanced Drug Delivery Новинка

Kun Cheng Advanced Drug Delivery

9956.09 руб.
Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.
Li Chun Drug Delivery Applications of Noninvasive Imaging. Validation from Biodistribution to Sites of Action Li Chun Drug Delivery Applications of Noninvasive Imaging. Validation from Biodistribution to Sites of Action Новинка

Li Chun Drug Delivery Applications of Noninvasive Imaging. Validation from Biodistribution to Sites of Action

13938.38 руб.
Cost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions In vivo imaging has become an important tool for the development of new drug delivery systems, shedding new light on the pharmacokinetics, biodistribution, bioavailability, local concentration, and clearance of drug substances for the treatment of human disease, most notably cancer. Written by a team of international experts, this book examines the use of quantitative imaging techniques in designing and evaluating novel drug delivery systems and applications. Drug Delivery Applications of Noninvasive Imaging offers a full arsenal of tested and proven methods, practices and guidance, enabling readers to overcome the many challenges in creating successful new drug delivery systems. The book begins with an introduction to molecular imaging. Next, it covers: In vivo imaging techniques and quantitative analysis Imaging drugs and drug carriers at the site of action, including low-molecular weight radiopharmaceuticals, peptides and proteins, siRNA, cells, and nanoparticles Applications of imaging techniques in administration routes other than intravenous injection, such as pulmonary and oral delivery Translational research leading to clinical applications Imaging drug delivery in large animal models Clinical applications of imaging techniques to guide drug development and drug delivery Chapters are based on a thorough review of the current literature as well as the authors' firsthand experience working with imaging techniques for the development of novel drug delivery systems. Presenting state-of-the-technology applications of imaging in preclinical and clinical evaluation of drug delivery systems, Drug Delivery Applications of Noninvasive Imaging offers cost-effective strategies to pharmaceutical researchers and students for developing drug delivery systems that accurately target a broad range of disease conditions.
Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi Новинка

Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi

16389.47 руб.
RNA interference (RNAi) is a process in living cells whereby small double stranded RNA interferes with the expression of specific genes with complementary nucleotide sequence. Like many nucleic acid-based therapies, RNAi has great potential in treating various life-threatening diseases. However, the poor stability and cellular uptake of RNAi molecules remain considerable barriers to their efficient delivery which is paramount to a successful therapy. This book provides a comprehensive introduction to RNAi delivery, then goes on to discuss different delivery strategies, and concludes with current applications in various diseases. It covers: Mechanisms, Barriers, and Analysis of RNAi Delivery Nonclinical Safety Assessments and Clinical Pharmacokinetics: A Regulatory Perspective Bioconjugation of siRNA for Site Specifi c Delivery Nanoscale Delivery Systems for RNAi Environmentally-Responsive Delivery Systems for RNAi Light-sensitive RNAi Viral-Mediated Delivery of shRNA and miRNA RNAi applications in Cancer Therapy, Liver Diseases, Hepatitis B, and Ocular Disease miRNA as therapeutic agents and targets Advanced Delivery and Therapeutic Applications of RNAi combines the essential aspects of developing RNAi therapeutics from bench to clinic, and is invaluable for researchers working on RNAi, drug discovery and delivery, biomedical engineering, biomaterials, molecular biology, and biotechnology.
Rasak Salaam Appraisal of Local Government Autonomy on Service Delivery at the Grassroots in Nigeria Rasak Salaam Appraisal of Local Government Autonomy on Service Delivery at the Grassroots in Nigeria Новинка

Rasak Salaam Appraisal of Local Government Autonomy on Service Delivery at the Grassroots in Nigeria

6627 руб.
Bachelor Thesis from the year 2016 in the subject Politics - International Politics - Region: Africa, grade: 70, Obafemi Awolowo University, course: Political Science, language: English, abstract: This term paper deals with the following questions: To what extent does Local Government autonomy influence service delivery in Nigeria? Do Local Government constitutional powers and functions enable execution of service delivery in Nigeria? Does Local Government autonomy has any impact on service delivery at the grassroots in Nigeria? It is a piece that revolves around Local Government. It aims at examining Local Government against the backdrop of its autonomy and the consequences on service delivery in Nigeria. Do access the groundbreaking analysis so as to be abreast with contemporary research on Local Government in Nigeria.The overall aim of this study is to critically examine the nexus between Local Government autonomy and effective social service delivery. In the light of this, the study seeks to examine the degree of Local Government autonomy on service delivery in Nigeria and to appraise constitutional powers and functions of Local Government as regards service delivery. It also examines the impact of Local Government autonomy on service delivery in Nigeria.Based on the aforementioned research questions, the following research assumptions are formulated for this study: Local Governments ineffectiveness and inefficiency on service delivery are due to their lack of autonomy. C...
Rebecca Bader A. Engineering Polymer Systems for Improved Drug Delivery Rebecca Bader A. Engineering Polymer Systems for Improved Drug Delivery Новинка

Rebecca Bader A. Engineering Polymer Systems for Improved Drug Delivery

10264.36 руб.
Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.
Yoon Yeo Nanoparticulate Drug Delivery Systems. Strategies, Technologies, and Applications Yoon Yeo Nanoparticulate Drug Delivery Systems. Strategies, Technologies, and Applications Новинка

Yoon Yeo Nanoparticulate Drug Delivery Systems. Strategies, Technologies, and Applications

12349.01 руб.
Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems. Nanoparticulate Drug Delivery Systems focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including: Lipid nanoparticles for the delivery of nucleic acids Multifunctional dendritic nanocarriers Polymer drug nanoconjugates Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including: Clearance of nanoparticles during circulation Drug delivery strategies for combatting multiple drug resistance Toxicological assessment of nanomedicine Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research. With its frank discussions of opportunities and challenges, Nanoparticulate Drug Delivery Systems sets a solid foundation for new research leading to the discovery and development of better nanomedicines.
Zhongwei Gu Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery Zhongwei Gu Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery Новинка

Zhongwei Gu Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery

13891.81 руб.
Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompassing small molecule delivery, delivery of therapeutic proteins and gene delivery. The carriers surveyed include polymeric, proteinaceous and lipid systems on the nanoscale, with a focus on their adaptability for different cargoes and target tissues. Thanks to the broad coverage of carriers as well as cargoes discussed, every researcher in the field will find valuable information here.
Juergen Siepmann Computational Pharmaceutics. Application of Molecular Modeling in Drug Delivery Juergen Siepmann Computational Pharmaceutics. Application of Molecular Modeling in Drug Delivery Новинка

Juergen Siepmann Computational Pharmaceutics. Application of Molecular Modeling in Drug Delivery

12349.01 руб.
Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems. Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field. This book is included in the Advances in Pharmaceutical Technology book series.
Tomalia Donald A. Dendrimer-Based Drug Delivery Systems. From Theory to Practice Tomalia Donald A. Dendrimer-Based Drug Delivery Systems. From Theory to Practice Новинка

Tomalia Donald A. Dendrimer-Based Drug Delivery Systems. From Theory to Practice

15284.7 руб.
The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include: Dendrimer history Synthesis Physicochemical properties Principles of drug delivery Applications in diverse biomedical fields Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth. Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.
Rickey Yada Nanotechnology and Functional Foods. Effective Delivery of Bioactive Ingredients Rickey Yada Nanotechnology and Functional Foods. Effective Delivery of Bioactive Ingredients Новинка

Rickey Yada Nanotechnology and Functional Foods. Effective Delivery of Bioactive Ingredients

15432.42 руб.
The continued advancement in the sciences of functional foods and nutraceuticals has clearly established a strong correlation between consumption of bioactives and improved human health and performance. However, the efficacy and bioavailability of these bioactive ingredients (e.g., omega-3 oils, carotenoid antioxidants, vitamins, and probiotic bacteria) in foods often remains a challenge, due to their instability in food products and gastrointestinal tract, as well as their limited bioavailability. In some cases, these bioactive ingredients may impart an undesirable organoleptic characteristic to the final product, which hinders acceptance by consumers. In addressing these challenges, development of effective delivery systems is critical to meet the consumer needs for effective bioactives. The scientific knowledge behind developing effective delivery of bioactive components into modern and wide-ranging food products will be essential to reap their health-promoting benefits and to support the sustained growth of the functional foods market. Nanotechnology and Functional Foods: Effective Delivery of Bioactive Ingredients explores the current data on all aspects of nanoscale packing, carrying and delivery mechanisms of bioactives ingredients to functional foods. The book presents various delivery systems (including nano-emulsions, solid lipid nanoparticles, and polymeric nano-particles), their properties and interactions with other food components, and fate in the human body. Later chapters emphasize the importance of consumers? attitude towards nano-delivery for the success of the technology and investigate the challenges faced by regulatory agencies to control risks and harmonize approaches worldwide. The wide applicability of bioactive delivery systems with the purpose of improving food quality, food safety and human health will make this book a worthy reference for a diverse range of readers in industry, research and academia.
Cohen Wayne R. Labor and Delivery Care. A Practical Guide Cohen Wayne R. Labor and Delivery Care. A Practical Guide Новинка

Cohen Wayne R. Labor and Delivery Care. A Practical Guide

9182.7 руб.
Labor and Delivery Care: A Practical Guide supports and reinforces the acquisition of the practical obstetric skills needed for aiding a successful birth. Beginning with the most important element of successful labor care, communicating with the patient, the authors guide you through normal delivery routines and examination techniques. They then address the best approaches to the full range of challenges that can arise during labor and delivery. Throughout, the 15 chapters provide concise practical guidance with: algorithmic decision trees clinical management tips detailed drawings Labor and Delivery Care: A Practical Guide provides a thorough tour-de-force of the practical obstetric skills needed for best and safest practice based on clinical experience and evidence.
Laurent Simon Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering Laurent Simon Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering Новинка

Laurent Simon Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering

8786.72 руб.
Enables readers to apply process dynamics and control theory to solve bioprocess and drug delivery problems The control of biological and drug delivery systems is critical to the health of millions of people worldwide. As a result, researchers in systems biology and drug delivery rely on process dynamics and control theory to build our knowledge of cell behavior and to develop more effective therapeutics, controlled release devices, and drug administration protocols to manage disease. Written by a leading expert and educator in the field, this text helps readers develop a deep understanding of process dynamics and control theory in order to analyze and solve a broad range of problems in bioprocess and drug delivery systems. For example, readers will learn how stability criteria can be used to gain new insights into the regulation of biological pathways and lung mechanics. They'll also learn how the concept of a time constant is used to capture the dynamics of diffusive processes. Readers will also master such topics as external disturbances, transfer functions, and input/output models with the support of the author's clear explanations, as well as: Detailed examples from the biological sciences and novel drug delivery technologies 160 end-of-chapter problems with step-by-step solutions Demonstrations of how computational software such as MATLAB and Mathematica solve complex drug delivery problems Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering is written primarily for undergraduate chemical and biomedical engineering students; however, it is also recommended for students and researchers in pharmaceutical engineering, process control, and systems biology. All readers will gain a new perspective on process dynamics and control theory that will enable them to develop new and better technologies and therapeutics to treat human disease.
Nahar Chowdhury Lutfun Steroid Dimers. Chemistry and Applications in Drug Design and Delivery Nahar Chowdhury Lutfun Steroid Dimers. Chemistry and Applications in Drug Design and Delivery Новинка

Nahar Chowdhury Lutfun Steroid Dimers. Chemistry and Applications in Drug Design and Delivery

15205.5 руб.
Steroid dimers are an important group of compounds produced by various marine organisms, and also synthesized in the laboratories. This group of compounds possesses various pharmacological and biological properties, and can also be used to create “molecular umbrellas” for drug delivery. Steroid Dimers: Chemistry and Applications in Drug Design and Delivery provides an up-to-date overview on the chemistry and applications of steroid dimers of natural and synthetic origins. The book includes easy-to-follow synthetic protocols for various classes of important dimeric steroids, source details, valuable spectroscopic data and depiction of unique structural features of natural steroidal dimers, and the Structure-Activity-Relationships (SARs) of some pharmacologically active dimeric steroids. Topics covered include: introduction to steroid dimers synthesis and chemistry of noncyclic and cyclic steroid dimers naturally occurring steroid dimers – cephalostatins, ritterazines and crellastatins biological and pharmacological functions of steroid dimers and their application in drug design and discovery steroid dimers as “molecular umbrellas” for drug delivery Steroid Dimers: Chemistry and Applications in Drug Design and Delivery is an essential guide to this important class of natural and synthetic compounds for researchers and students of natural products chemistry and biochemistry, synthetic organic and medicinal chemistry, and drug design, discovery and delivery.
Pathak Yashwant Antibody-Mediated Drug Delivery Systems. Concepts, Technology, and Applications Pathak Yashwant Antibody-Mediated Drug Delivery Systems. Concepts, Technology, and Applications Новинка

Pathak Yashwant Antibody-Mediated Drug Delivery Systems. Concepts, Technology, and Applications

13063.27 руб.
This book covers various aspects of antibody mediated drug delivery systems – theoretical aspects, processing, viral and non-viral vectors, and fields where these systems find and /or are being evaluated for applications as therapeutics and diagnostic treatment. Chapters discuss actual applications of techniques used for formulation and characterization. Applications areas include cancer, pulmonary, ocular diseases; brain drug delivery; and vaccine delivery. The contributing authors represent over 10 different countries, covering recent developments happening around the globe.
Kwok Chow Therapeutic Delivery Solutions Kwok Chow Therapeutic Delivery Solutions Новинка

Kwok Chow Therapeutic Delivery Solutions

9956.09 руб.
Provides a comprehensive review of all types of medical therapeutic delivery solutions from traditional pharmaceutical therapy development to innovative medical device therapy treatment to the recent advances in cellular and stem cell therapy development • Provides information to potentially allow future development of treatments with greater therapeutic potential and creativity • Includes associated regulatory requirements for the development of these therapies • Provides a comprehensive developmental overview on therapeutic delivery solutions • Provides overview information for both the general reader as well as more detailed references for professionals and specialists in the field
David Boberski CDS Delivery Option. Better Pricing of Credit Default Swaps David Boberski CDS Delivery Option. Better Pricing of Credit Default Swaps Новинка

David Boberski CDS Delivery Option. Better Pricing of Credit Default Swaps

5276.39 руб.
For traders trying to navigate the increasingly volatile credit default swap market, CDS Delivery Option provides worked-out examples, over 30 charts, a case study of Delphi, and detailed explanations of how the subprime crisis caused the credit crisis and the near collapse of the GSEs. The book includes detailed information on: how to value a CDS contract how to value the delivery option how contract value changes when the yield curve flattens or becomes steeper how contract value changes with bullish or bearish market moves how to figure out when to buy protection and when to sell protection how to hedge CDS risk when and how to unwind a contract prior to settlement when to hold a trade through delivery how to navigate a «squeeze» (when the notional value of contracts going through delivery is larger than the supply of the cheapest-to-deliver issue) when buying contracts can make their prices go down how to construct a basis trade how to find arbitrage opportunities how to analyze default probability and corporate debt when to settle via auction and when to settle via physical delivery which note is the cheapest to deliver This book is an indispensable resource for all market professionals working in the CDS market.
Delivery Fest Delivery Fest Новинка

Delivery Fest

250 руб.
Dionysios Douroumis Drug Delivery Strategies for Poorly Water-Soluble Drugs Dionysios Douroumis Drug Delivery Strategies for Poorly Water-Soluble Drugs Новинка

Dionysios Douroumis Drug Delivery Strategies for Poorly Water-Soluble Drugs

15203.96 руб.
Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies. Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, self–microemulsifying drug delivery systems, nanocrystals, hydrosol colloidal dispersions, microemulsions, solid dispersions, cosolvent use, dendrimers, polymer- drug conjugates, polymeric micelles, and mesoporous silica nanoparticles. For each approach the book discusses the main instrumentation, operation principles and theoretical background, with a focus on critical formulation features and clinical studies. Finally, the book includes some recent and novel applications, scale-up considerations and regulatory issues. Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug delivery, polymers and biomaterials.
K. Mittal L. Adhesion in Pharmaceutical, Biomedical, and Dental Fields K. Mittal L. Adhesion in Pharmaceutical, Biomedical, and Dental Fields Новинка

K. Mittal L. Adhesion in Pharmaceutical, Biomedical, and Dental Fields

17365.5 руб.
The phenomenon of adhesion is of cardinal importance in the pharmaceutical, biomedical and dental fields. A few eclectic examples will suffice to underscore the importance/relevance of adhesion in these three areas. For example, the adhesion between powdered solids is of crucial importance in tablet manufacture. The interaction between biodevices (e.g., stents, bio-implants) and body environment dictates the performance of such devices, and there is burgeoning research activity in modifying the surfaces of such implements to render them compatible with bodily components. In the field of dentistry, the modern trend is to shift from retaining of restorative materials by mechanical interlocking to adhesive bonding. This unique book addresses all these three areas in an easily accessible single source. The book contains 15 chapters written by leading experts and is divided into four parts: General Topics; Adhesion in Pharmaceutical Field; Adhesion in Biomedical Field; and Adhesion in Dental Field. The topics covered include: – Theories or mechanisms of adhesion. – Wettability of powders. – Role of surface free energy in tablet strength and powder flow behavior. – Mucoadhesive polymers for drug delivery systems. – Transdermal patches. – Skin adhesion in long-wear cosmetics. – Factors affecting microbial adhesion. – Biofouling and ways to mitigate it. – Adhesion of coatings on surgical tools and bio-implants. – Adhesion in fabrication of microarrays in clinical diagnostics. – Antibacterial polymers for dental adhesives and composites. – Evolution of dental adhesives. – Testing of dental adhesives joints.
Nissim Garti Self-Assembled Supramolecular Architectures. Lyotropic Liquid Crystals Nissim Garti Self-Assembled Supramolecular Architectures. Lyotropic Liquid Crystals Новинка

Nissim Garti Self-Assembled Supramolecular Architectures. Lyotropic Liquid Crystals

11879.3 руб.
This book will describe fundamentals and recent developments in the area of Self-Assembled Supramolecular Architecture and their relevance to the understanding of the functionality of membranes as delivery systems for active ingredients. As the heirarchial architectures determine their performance capabilities, attention will be paid to theoretical and design aspects related to the construction of lyotropic liquid crystals: mesophases such as lamellar, hexagonal, cubic, sponge phase micellosomes. The book will bring to the reader mechanistic aspects, compositional considerations, transition within phases, solubilization capacities, drug entrapment and release mechanisms and transmembrane, transdermal, and other transport phenomena. It will stress the importance of these mesostructures to crystallization and polymorphism of drugs, fats, and nutraceuticals and will discuss regioselectivity of organic and enzymatic reactions that take place at interfaces and within the channels of the mesophase. The book will bring studies on the use of these mesophase as crystallization or particulation media for the formation of nanoparticles and nanocrystals. Chapters will discuss applications in the areas of pharmaceuticals, food, cosmetics, plastics, paper, agro-chemistry and industrial applications.
Sarmento Bruno Chitosan-Based Systems for Biopharmaceuticals. Delivery, Targeting and Polymer Therapeutics Sarmento Bruno Chitosan-Based Systems for Biopharmaceuticals. Delivery, Targeting and Polymer Therapeutics Новинка

Sarmento Bruno Chitosan-Based Systems for Biopharmaceuticals. Delivery, Targeting and Polymer Therapeutics

17343.78 руб.
Chitosan is a linear polysaccharide commercially produced by the deacetylation of chitin. It is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with otherwise unstable biomolecules – making it a valuable component in the formulation of biopharmaceutical drugs. Chitosan-Based Systems for Biopharmaceuticals provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. The book is divided in four different parts. Part I discusses general aspects of chitosan and its derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems. Part II deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. Part III discusses specific applications of chitosan and its derivatives for biopharmaceutical use. Finally, Part IV presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related to the development of biopharmaceutical products, as well as their patent status, and clinical application and potential. Topics covered include: chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals physical properties of chitosan and derivatives in sol and gel states absorption promotion properties of chitosan and derivatives biocompatibility and biodegradation of chitosan and derivatives biological and pharmacological activity of chitosan and derivatives biological, chemical and physical compatibility of chitosan and biopharmaceuticals approaches for functional modification or crosslinking of chitosan use of chitosan and derivatives in conventional biopharmaceutical dosage forms manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals chitosan and derivatives for biopharmaceutical use: mucoadhesive properties chitosan-based systems for mucosal delivery of biopharmaceuticals chitosan-based delivery systems for mucosal vaccination chitosan-based nanoparticulates for oral delivery of biopharmaceuticals chitosan-based systems for ocular delivery of biopharmaceuticals chemical modification of chitosan for delivery of DNA and siRNA target-specific chitosan-based nanoparticle systems for nucleic acid delivery functional PEGylated chitosan systems for biopharmaceuticals stimuli-sensitive chitosan-based systems for biopharmaceuticals chitosan copolymers for biopharmaceuticals application of chitosan for anti-cancer biopharmaceutical delivery chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine wound healing properties of chitosan and its use in wound dressing biopharmaceuticals toxicological properties of chitosan and derivatives for biopharmaceutical applications regulatory status of chitosan and derivatives patentability and intellectual property issues quality control and good manufacturing practice preclinical and clinical use of chitosan and derivatives for biopharmaceuticals Chitosan-Based Systems for Biopharmaceuticals is an important compendium of fundamental concepts, practical tools and applications of chitosan-based biopharmaceuticals for researchers in academia and industry working in drug formulation and delivery, biopharmaceuticals, medicinal chemistry, pharmacy, bioengineering and new materials development.
Amit Misra Delivery Systems for Tuberculosis Prevention and Treatment Amit Misra Delivery Systems for Tuberculosis Prevention and Treatment Новинка

Amit Misra Delivery Systems for Tuberculosis Prevention and Treatment

13120.04 руб.
Provides a review of novel pharmaceutical approaches for Tuberculosis drugs Presents a novel perspective on tuberculosis prevention and treatment Considers the nature of disease, immunological responses, vaccine and drug delivery, disposition and response Multidisciplinary appeal, with contributions from microbiology, immunology, molecular biology, pharmaceutics, pharmacokinetics, chemical and mechanical engineering
Syed Tahira, Aslam Farheen, Naz Shagufta Microbial load detection on delivery kits after gamma sterilization Syed Tahira, Aslam Farheen, Naz Shagufta Microbial load detection on delivery kits after gamma sterilization Новинка

Syed Tahira, Aslam Farheen, Naz Shagufta Microbial load detection on delivery kits after gamma sterilization

7414 руб.
Delivery kits are the simple and disposable kits that help to achieve safe delivery of babies. The birthing kit comprises of different disposable instruments. These disposable instruments may have a huge microbial load on them which can be very dangerous for the neonate as well as for the mother. So, sterilization is indeed a prerequisite for birth procedures using these kits. But what type of microbial load is present? What are the health effects of that bio burden? What type of sterilization should be done? What are the effects of that sterilization procedure are the important points to note, as you will see in this book.
Linda Goodnight In the Spirit of...Christmas and A Very Special Delivery: In the Spirit of...Christmas / A Very Special Delivery Linda Goodnight In the Spirit of...Christmas and A Very Special Delivery: In the Spirit of...Christmas / A Very Special Delivery Новинка

Linda Goodnight In the Spirit of...Christmas and A Very Special Delivery: In the Spirit of...Christmas / A Very Special Delivery

120.09 руб.
Heartwarming stories of holiday romance by RITA Award-winning author Linda GoodnightIn the Spirit of…ChristmasFor his daughter's sake, widowed father Jesse Slater returns to Oklahoma to reclaim the family ranch. But their home is now a Christmas tree farm…run by a woman whose faith will change their lives forever. A Very Special Delivery Molly McCreight has met the man of her dreams! But with her painful secret, how can she hope to spend the holidays–let alone the rest of her life –with single father Ethan Hunter and his precious baby girl?
Asare Okyere Seth Public-Private Partnerships in Health Care in Ghana Asare Okyere Seth Public-Private Partnerships in Health Care in Ghana Новинка

Asare Okyere Seth Public-Private Partnerships in Health Care in Ghana

9064 руб.
health care is a necessity for fostering human development. Yet Ghana, as other developing countries, is struggling to provide improved, quality and affordable health care to its citizens.Against the backdrop of limited public funds and competition from other sectors of the economy; inadequacy is but a lightening of the actual challenges in health care delivery. Undoubtedly, Public-Private Partnerships in health care seems to be the innovation. But what can and will the private sector do in health care delivery? What are the prospects and challenges of a policy that fosters intense private sector support. This work, explores the nuisances of this approach through a local context. The research work tried to explore this by analysing the contribution of the private sector in local level heath care delivery.
Tina Evans Marie Introduction to Health Care Services: Foundations and Challenges Tina Evans Marie Introduction to Health Care Services: Foundations and Challenges Новинка

Tina Evans Marie Introduction to Health Care Services: Foundations and Challenges

6945.91 руб.
A comprehensive guide to the structure, synergy, and challenges in U.S. health care delivery Introduction to Health Care Services: Foundations and Challenges offers new insights into the most important sectors of the United States' health care industry and the many challenges the future holds. Designed to provide a comprehensive and up-to-date understanding of the system, this textbook covers the many facets of health care delivery and details the interaction of health, environments, organizations, populations, and the health professions. Written by authors with decades of experience teaching and working in health care administration and management, the book examines the current state and changing face of health care delivery in the United States. Each chapter includes learning objectives and discussion questions that help guide and engage deeper consideration of the issues at hand, providing a comprehensive approach for students. Cases studies demonstrating innovations in the delivery of health care services are also presented. Health care administration requires a thorough understanding of the multiple systems that define and shape the delivery of health care in the United States. At the same time, it is important for students to gain an appreciation of the dilemma confronting policy makers, providers, and patients in the struggle to balance cost, quality, and access. Introduction to Health Care Services: Foundations and Challenges is an in-depth examination of the major health care issues and policy changes that have had an impact on the U.S. health care delivery system. Includes information on U.S. health care delivery, from care to cost, and the forces of change Focuses on major industry players, including providers, insurers, and facilities Highlights challenges facing health care delivery in the future, including physician shortages, quality care, and the chronic disease epidemic The U.S. health care system is undergoing major reform, and the effects will ripple across every sector of the industry. Introduction to Health Care Services: Foundations and Challenges gives students a complete introduction to understanding the issues and ramifications.
Millicent Awialie Akaateba The Church and the State as Partners in Rural Health Care Delivery Millicent Awialie Akaateba The Church and the State as Partners in Rural Health Care Delivery Новинка

Millicent Awialie Akaateba The Church and the State as Partners in Rural Health Care Delivery

8789 руб.
Health services provision remain an essential part of the responsibilities of governments throughout the world in view of the vital role good health plays in economic development. However, in the developing world, the public sector (government) is no longer able to solely provide sustainable basic infrastructure, including health services in response to the rapidly growing demand due to increasing population growth and weak economies. This book used the Upper East Region of Ghana as a case study to examine the contribution of the Catholic Church (a not-for-profit health care provider) to improving access to health care delivery in rural communities. The research used secondary and primary data sources which produced results indicating the immense health care delivery gap being filled by the Catholic Church in rural Ghana. It outlined several dimensions of health care access and identified public-private partnerships as a viable policy for governments to adopt for improved access to health care. This book is useful to government and nongovernmental actors in rural health delivery, persons in academia or anyone with an interest in Church-State partnerships in rural health delivery.
Dom Robinson Content Delivery Networks. Fundamentals, Design, and Evolution Dom Robinson Content Delivery Networks. Fundamentals, Design, and Evolution Новинка

Dom Robinson Content Delivery Networks. Fundamentals, Design, and Evolution

9183.59 руб.
The definitive guide to developing robust content delivery networks This book examines the real-world engineering challenges of developing robust content delivery networks (CDNs) and provides the tools required to overcome those challenges and to ensure high-quality content delivery that fully satisfies operators’ and consumers' commercial objectives. It is informed by the author’s two decades of experience building and delivering large, mission-critical live video, webcasts, and radio streaming, online and over private IP networks. Following an overview of the field, the book cuts to the chase with in-depth discussions—laced with good-natured humor—of a wide range of design considerations for different network topologies. It begins with a description of the author's own requirement filtration processes. From there it moves on to initial sketches, through considerations of stakeholder roles and responsibilities, to the complex challenges of managing change in established teams. Agile versus waterfall considerations within large blue chip companies, security, commercial models, and value chain alignment are explored in detail. Featured throughout the book are numerous «what if» scenarios that help provide a clear picture of the wide spectrum of practical contexts for which readers may be tasked with building and implementing a CDN. In addition, the book: Discusses delivery of live, catch-up, scheduled on-demand, TVOD and SVOD Offers insights into the decisions that can to be made when architecting a content distribution system over IP-based networks Covers CDN topologies, including Edge-Caching, Streaming-Splitting, Pure-Play, Operator, Satellite, and Hybrid Examines computer hosting and orchestration for dedicated appliances and virtualization Includes real-world cases covering everything from IETF, regulatory considerations, and policy formation, to coding, hardware vendors, and network operators Considers the future of CDN technologies and the market forces driving its evolution Written by a back-room engineer for back-room engineers, Content Delivery Networks gets readers up to speed on the real-world challenges they can face as well as tried-and-true strategies for addressing those challenges in order to ensure the delivery of the high-quality content delivery networks that clients demand and users expect.
Martin Fischer Integrating Project Delivery Martin Fischer Integrating Project Delivery Новинка

Martin Fischer Integrating Project Delivery

5788.99 руб.
A revolutionary, collaborative approach to design and construction project delivery Integrating Project Delivery is the first book-length discussion of IPD, the emergent project delivery method that draws on each stakeholder's unique knowledge to address problems before they occur. Written by authors with over a decade of research and practical experience, this book provides a primer on IPD for architects, designers, and students interested in this revolutionary approach to design and construction. With a focus on IPD in everyday operation, coverage includes a detailed explanation and analysis of IPD guidelines, and case studies that show how real companies are applying these guidelines on real-world projects. End-of-chapter questions help readers quickly review what they've learned, and the online forum allows them to share their insights and ideas with others who either have or are in the process of implementing IPD themselves. Integrating Project Delivery brings together the owners, architect, engineers, and contractors early in the development stage to ensure that problems are caught early, and to address them in a collaborative way. This book describes the parameters of this new, more efficient approach, with expert insight on real-world implementation. Compare traditional procurement with IPD Understand IPD guidelines, and how they're implemented Examine case studies that illustrate everyday applications Communicate with other IPD adherents in the online forum The IPD approach revolutionizes not only the workflow, but the relationships between the stakeholders – the atmosphere turns collaborative, and the team works together toward a shared goal instead of viewing one another as obstructions to progress. Integrated Project Delivery provides a deep exploration of this approach, with practical guidance and expert insight.
Desta Tesfaw Public Service Delivery Reform and Customer Satisfaction in Ethiopia Desta Tesfaw Public Service Delivery Reform and Customer Satisfaction in Ethiopia Новинка

Desta Tesfaw Public Service Delivery Reform and Customer Satisfaction in Ethiopia

8377 руб.
The central focus of this work is identifying and analyzing the factors that determine the success and failures of public service delivery in relation to customer satisfaction. Currently civil service reform program is undergoing in Ethiopia. The main element of the reform program is delivering efficient and effective service to the public. In this regard there are some public institutions that are successful in satisfying their customers by implementing the reform program. On the contrary there are others still not successful. Therefore the major public service delivery factors that were suggested by different researchers and scholars are tested using case study method in this work. Two public organizations are selected i.e. one from the category of successful once and the other from those who are not successful based on the previous researches and preliminary assessments. By designing the conceptual framework, the public service delivery success factors are identified scientifically. In addition different approaches and methods of public service delivery reforms are analysed.
Hyojung Kang Healthcare Systems Engineering Hyojung Kang Healthcare Systems Engineering Новинка

Hyojung Kang Healthcare Systems Engineering

9647.09 руб.
Apply engineering and design principles to revitalize the healthcare delivery system Healthcare Systems Engineering is the first engineering book to cover this emerging field, offering comprehensive coverage of the healthcare system, healthcare delivery, and healthcare systems modeling. Written by leading industrial engineering authorities and a medical doctor specializing in healthcare delivery systems, this book provides a well-rounded resource for readers of a variety of backgrounds. Examples, case studies, and thoughtful learning activities are used to thoroughly explain the concepts presented, including healthcare systems, delivery, quantification, and design. You'll learn how to approach the healthcare industry as a complex system, and apply relevant design and engineering principles and processes to advance improvements. Written with an eye toward practicality, this book is designed to maximize your understanding and help you quickly apply toward solutions for a variety of healthcare challenges. Healthcare systems engineering is a new and complex interdisciplinary field that has emerged to address the myriad challenges facing the healthcare industry in the wake of reform. This book functions as both an introduction and a reference, giving you the knowledge you need to move toward better healthcare delivery. Understand the healthcare delivery context Use appropriate statistical and quantitative models Improve existing systems and design new ones Apply systems engineering to a variety of healthcare contexts Healthcare systems engineering overlaps with industrial engineering, operations research, and management science, uniting the principles and practices of these fields together in pursuit of optimal healthcare operations. Although collaboration is focused on practitioners, professionals in information technology, policy and administration, public health, and law all play crucial roles in revamping health care systems. Healthcare Systems Engineering is a complete and authoritative reference for stakeholders in any field.
Success Experts Delivery & Courier Services Sales Affirmations Workbook for Instant Success. Delivery & Courier Services Sales Positive & Empowering Affirmations Workbook. Includes. Delivery & Courier Services Sales Subliminal Empowerment. Success Experts Delivery & Courier Services Sales Affirmations Workbook for Instant Success. Delivery & Courier Services Sales Positive & Empowering Affirmations Workbook. Includes. Delivery & Courier Services Sales Subliminal Empowerment. Новинка

Success Experts Delivery & Courier Services Sales Affirmations Workbook for Instant Success. Delivery & Courier Services Sales Positive & Empowering Affirmations Workbook. Includes. Delivery & Courier Services Sales Subliminal Empowerment.

1002 руб.
"Do you want an interactive workbook and diary that will support you in reaching your goals and improving your results? Well then this book is for you!" This is a strategically composed workbook of affirmations which is intended to communicate with your subconscious mind through the regular subliminal messaging of positive affirmations. Through years of corporate Business to Business (B2B) sales experience, we discovered that this form of positive programming yielded highly profitable results for sales teams across the globe. It is now your turn to experience instant positive changes. We wish you great successes and achievements.
Graham Thomas Media Production, Delivery and Interaction for Platform Independent Systems. Format-Agnostic Media Graham Thomas Media Production, Delivery and Interaction for Platform Independent Systems. Format-Agnostic Media Новинка

Graham Thomas Media Production, Delivery and Interaction for Platform Independent Systems. Format-Agnostic Media

9107.44 руб.
Presents current trends and potential future developments by leading researchers in immersive media production, delivery, rendering and interaction The underlying audio and video processing technology that is discussed in the book relates to areas such as 3D object extraction, audio event detection; 3D sound rendering and face detection, gesture analysis and tracking using video and depth information. The book will give an insight into current trends and developments of future media production, delivery and reproduction. Consideration of the complete production, processing and distribution chain will allow for a full picture to be presented to the reader. Production developments covered will include integrated workflows developed by researchers and industry practitioners as well as capture of ultra-high resolution panoramic video and 3D object based audio across a range of programme genres. Distribution developments will include script based format agnostic network delivery to a full range of devices from large scale public panoramic displays with wavefield synthesis and ambisonic audio reproduction to ’small screen’ mobile devices. Key developments at the consumer end of the chain apply to both passive and interactive viewing modes and will incorporate user interfaces such as gesture recognition and ‘second screen’ devices to allow manipulation of the audio visual content. Presents current trends and potential future developments by leading researchers in immersive media production, delivery, rendering and interaction. Considers the complete production, processing and distribution chain illustrating the dependencies and the relationship between different components. Proposes that a format-agnostic approach to the production and delivery of broadcast programmes will overcome the problems faced with the steadily growing number of production and delivery formats. Explains the fundamentals of media production in addition to the complete production chain, beyond current-state-of-the-art through to presenting novel approaches and technologies for future media production. Focuses on the technologies that will allow for the realization of an E2E media platform that supports flexible content representations and interactivity for users. An essential read for Researchers and developers of audio-visual technology in industry and academia, such as engineers in broadcast technology companies and students working toward a career in the rapidly changing area of broadcast both from a production and an engineering perspective.
Johannes Fink Karl 3D Industrial Printing with Polymers Johannes Fink Karl 3D Industrial Printing with Polymers Новинка

Johannes Fink Karl 3D Industrial Printing with Polymers

18531.7 руб.
3D industrial printing has become mainstream in manufacturing. This unique book is the first to focus on polymers as the printing material. The scientific literature with respect to 3D printing is collated in this monograph. The book opens with a chapter on foundational issues such and presents a broad overview of 3D printing procedures and the materials used therein. In particular, the methods of 3d printing are discussed and the polymers and composites used for 3d printing are detailed. The book details the main fields of applications areas which include electric and magnetic uses, medical applications, and pharmaceutical applications. Electric and magnetic uses include electronic materials, actuators, piezoelectric materials, antennas, batteries and fuel cells. Medical applications are organ manufacturing, bone repair materials, drug-eluting coronary stents, and dental applications. The pharmaceutical applications are composite tablets, transdermal drug delivery, and patient-specific liquid capsules. A special chapter deals with the growing aircraft and automotive uses for 3D printing, such as with manufacturing of aircraft parts and aircraft cabins. In the field of cars, 3D printing is gaining importance for automotive parts (brake components, drives), for the fabrication of automotive repair systems, and even 3D printed vehicles.
Venkatesh Ganapathy Mumbai Dabbawalas. Social entrepreneurs who make India proud Venkatesh Ganapathy Mumbai Dabbawalas. Social entrepreneurs who make India proud Новинка

Venkatesh Ganapathy Mumbai Dabbawalas. Social entrepreneurs who make India proud

3414 руб.
Academic Paper from the year 2017 in the subject Business economics - Business Management, Corporate Governance, grade: -, , language: English, abstract: This book talks about the entrepreneurial abilities of famed food delivery men of Mumbai. It argues the reasons why the business model is not scalable outside Mumbai and presents a road map to achieve scalability of the model. Additionally, this research also suggests that the Mumbai dabbawalas can also be gainfully used to incubate start ups in food delivery space.
Bob Boiko Content Management Bible Bob Boiko Content Management Bible Новинка

Bob Boiko Content Management Bible

3959.11 руб.
Written by one of the leading experts in content management systems (CMS), this newly revised bestseller guides readers through the confusing-and often intimidating-task of building, implementing, running, and managing a CMS Updated to cover recent developments in online delivery systems, as well as XML and related technologies Reflects valuable input from CMS users who attended the author's workshops, conferences, and courses An essential reference showing anyone involved in information delivery systems how to plan and implement a system that can handle large amounts of information and help achieve an organization's overall goals
Mustafa Guler O. Therapeutic Nanomaterials Mustafa Guler O. Therapeutic Nanomaterials Новинка

Mustafa Guler O. Therapeutic Nanomaterials

11576.51 руб.
Addressing a cutting-edge, multidisciplinary field, this book reviews nanomaterials and their biomedical applications. It covers regeneration, implants, adhesives, and biosensors and strategies for more efficient therapy, diagnosis, and drug delivery with the use of nanotechnology. • Addresses the increasing demand for nanomedicine in a cutting-edge, multidisciplinary field • Introduces concepts, strategies, and requirements of developing materials • Discusses hot topics in drug delivery, such as neural regeneration, cartilage regeneration, bone tissue regeneration, dental regeneration, biomedical imaging, tissue adhesives and biosensors • Includes a chapter about nanotoxicology to help readers further understand the biocompatability of nanomaterials
Dr. Samuel Taddesse Social Accountability in Ethiopia. Establishing Collaborative Relationships between Citizens and the State Dr. Samuel Taddesse Social Accountability in Ethiopia. Establishing Collaborative Relationships between Citizens and the State Новинка

Dr. Samuel Taddesse Social Accountability in Ethiopia. Establishing Collaborative Relationships between Citizens and the State

1552 руб.
Social Accountability in Ethiopia is a comprehensive guidebook with numerous examples on the use of social accountability-a process by which citizens, communities, policymakers, and government officials are engaged in constructive dialogue about justifications for policies and actions, among other elements. It offers detailed and thorough discussion of how social accountability tools are used to objectively assess government service delivery performance and the mechanisms used for addressing service delivery deficits in constructive and collaborative processes between citizens and government actors. It also discusses how the social accountability practice can be sustained, regularized and mainstreamed in government service delivery decisions. It also enables citizens to voice their needs and concerns and work collaboratively to enhance the access, quality, and equity of the public services they use.
John Rees ABC of Asthma John Rees ABC of Asthma Новинка

John Rees ABC of Asthma

3546.18 руб.
Asthma is a common condition with increasing prevalence. This new edition of the highly regarded ABC of Asthma has been thoroughly revised with reference to the latest British Thoracic Society guidelines on the management of asthma in children and adults. It covers the advances in practice and methods, with a new emphasis on delivery systems, self-dose assessment and delivery of care with different pharmacological approaches. The ABC of Asthma is a concise, up-to-date overview of all aspects of asthma and includes two new chapters focussing on GP practice issues including clinical management and organisation of asthma care. It is ideal for GPs, junior doctors and medical students, nurses, and anyone dealing with the treatment of asthma in children and adults.
Meseret Ayenew Assessing the effectiveness of service delivery reform. The quest for customer satisfaction in public institutions of Arba Minch town Meseret Ayenew Assessing the effectiveness of service delivery reform. The quest for customer satisfaction in public institutions of Arba Minch town Новинка

Meseret Ayenew Assessing the effectiveness of service delivery reform. The quest for customer satisfaction in public institutions of Arba Minch town

6239 руб.
Master's Thesis from the year 2016 in the subject Business economics - Marketing, Corporate Communication, CRM, Market Research, Social Media, , language: English, abstract: Public services are funded by taxpayers' money. Thus, the ultimate goal of public institutions is providing services to citizens in an effective way. This day, improved services are provided by public institutions due to the implementation of different tools such as BPR, BSC, change army, and citizens' charter. In addition, the services provided by the institutions are causes of satisfaction and dissatisfaction to citizens. Accordingly, to improve the quality of the services provided by the institution continuous follow up and study is needed. Therefore, this study was conducted to assess the effectiveness of service delivery reform, the quest for customer satisfaction in public institutions of AMTA. Accordingly, the study has examined the status of the existing service delivery of the institutions of AMTA. Additionally, attempts have been made to investigate the factors that affect the effectiveness of service delivery of the institutions. To this purpose, data was gathered through questionnaire, interview, FGD, and review of published and unpublished documents. A total of 203 individuals were consulted from 4 institutions and 2 Kebeles i.e. 65 employees, 88 customers, 4 head of offices, 2 Kebele managers, 44 management bodies of the offices and AMTA steering committees. The study result reve...
Susheel Kalia Biodegradable and Biobased Polymers for Environmental and Biomedical Applications Susheel Kalia Biodegradable and Biobased Polymers for Environmental and Biomedical Applications Новинка

Susheel Kalia Biodegradable and Biobased Polymers for Environmental and Biomedical Applications

17365.5 руб.
This volume incorporates 13 contributions from renowned experts from the relevant research fields that are related biodegradable and biobased polymers and their environmental and biomedical applications. Specifically, the book highlights: Developments in polyhydroxyalkanoates applications in agriculture, biodegradable packaging material and biomedical field like drug delivery systems, implants, tissue engineering and scaffolds The synthesis and elaboration of cellulose microfibrils from sisal fibres for high performance engineering applications in various sectors such as the automotive and aerospace industries, or for building and construction The different classes and chemical modifications of tannins Electro-activity and applications of Jatropha latex and seed The synthesis, properties and applications of poly(lactic acid) The synthesis, processing and properties of poly(butylene succinate), its copolymers, composites and nanocomposites The different routes for preparation polymers from vegetable oil and the effects of reinforcement and nano-reinforcement on the physical properties of such biobased polymers The different types of modified drug delivery systems together with the concept of the drug delivery matrix for controlled release of drugs and for antitumor drugs The use of nanocellulose as sustainable adsorbents for the removal of water pollutants mainly heavy metal ions, organic molecules, dyes, oil and CO2 The main extraction techniques, structure, properties and different chemical modifications of lignins Proteins and nucleic acids based biopolymers The role of tamarind seed polysaccharide-based multiple-unit systems in sustained drug release
Ian Colbeck Aerosol Science. Technology and Applications Ian Colbeck Aerosol Science. Technology and Applications Новинка

Ian Colbeck Aerosol Science. Technology and Applications

15203.96 руб.
Aerosols influence many areas of our daily life. They are at the core of environmental problems such as global warming, photochemical smog and poor air quality. They can also have diverse effects on human health, where exposure occurs in both outdoor and indoor environments. However, aerosols can have beneficial effects too; the delivery of drugs to the lungs, the delivery of fuels for combustion and the production of nanomaterials all rely on aerosols. Advances in particle measurement technologies have made it possible to take advantage of rapid changes in both particle size and concentration. Likewise, aerosols can now be produced in a controlled fashion. Reviewing many technological applications together with the current scientific status of aerosol modelling and measurements, this book includes: • Satellite aerosol remote sensing • The effects of aerosols on climate change • Air pollution and health • Pharmaceutical aerosols and pulmonary drug delivery • Bioaerosols and hospital infections • Particle emissions from vehicles • The safety of emerging nanomaterials • Radioactive aerosols: tracers of atmospheric processes With the importance of this topic brought to the public’s attention after the eruption of the Icelandic volcano Eyjafjallajökull, this book provides a timely, concise and accessible overview of the many facets of aerosol science.
A History of Photography A History of Photography Новинка

A History of Photography

1700 руб.
From a delivery boy to one of the most important industrialists in American history, George Eastman's career developed in a particularly American way. The founder of...
Rejoice Makaudze Residents. Participation in Service Delivery Rejoice Makaudze Residents. Participation in Service Delivery Новинка

Rejoice Makaudze Residents. Participation in Service Delivery

8864 руб.
This study delves into resident‟s participation in service delivery in Masvingo‟s Ward 1 community. The study looked at how residents of Ward 1 have participated in service delivery. It is premised on the participatory governance theory which talks about an all inclusive governance structure in which citizens and the government work together in order to improve on the management and service provision in a community. It visions citizens being involved in policy making as well as implementation. The study showed that the residents are quite aware of most of the responsibilities of the city council, but however most of the respondents said the council was failing to effectively provide services in the Ward. The residents expressed concern about poor service delivery and which they imputed to issues such as corruption by the council officials, party politics, unemployment on the part the residents themselves as well as besetting financial constraints faced by the city council..
Janet Snoddon Case Management of Long-term Conditions. Principles and Practice for Nurses Janet Snoddon Case Management of Long-term Conditions. Principles and Practice for Nurses Новинка

Janet Snoddon Case Management of Long-term Conditions. Principles and Practice for Nurses

4706.76 руб.
The importance of appropriate and effective management of patient with long term chronic conditions cannot be underestimated. Case Management of Long-Term Conditions aims to provide all appropriate practitioners (including nurses, pharmacists, physiotherapists, and social care practitioners) who might be involved in delivery of proactive case management with a practical understanding of how their knowledge and skills can be utilised to improve outcomes for people with chronic long-term conditions. The text contains some broad reflections on care and service delivery based on reviews of evidence and views from clinicians in the use of these skills and competencies to deliver improved outcomes for clients.
Janet Snoddon Case Management of Long-term Conditions. Principles and Practice for Nurses Janet Snoddon Case Management of Long-term Conditions. Principles and Practice for Nurses Новинка

Janet Snoddon Case Management of Long-term Conditions. Principles and Practice for Nurses

4830.25 руб.
The importance of appropriate and effective management of patient with long term chronic conditions cannot be underestimated. Case Management of Long-Term Conditions aims to provide all appropriate practitioners (including nurses, pharmacists, physiotherapists, and social care practitioners) who might be involved in delivery of proactive case management with a practical understanding of how their knowledge and skills can be utilised to improve outcomes for people with chronic long-term conditions. The text contains some broad reflections on care and service delivery based on reviews of evidence and views from clinicians in the use of these skills and competencies to deliver improved outcomes for clients.
Fotedar Shailee Pharmacology of Fluorides Fotedar Shailee Pharmacology of Fluorides Новинка

Fotedar Shailee Pharmacology of Fluorides

6439 руб.
The book gives information about brief history of fluorides,sources of fluorides,Pharmokinetics of fluorides in human beings (general body and oral cavity,pharmacologic actions, modes of delivery (systemic and topical),slow release fluorides( incorporation of fluorides in dental materials and using intra oral devices such as copolymer membrane device and fluoride glass device), and toxicity of fluorides.
Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development Новинка

Rossi John J. RNA Interference. Application to Drug Discovery and Challenges to Pharmaceutical Development

11008.15 руб.
RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects.
Eric Bauer Lean Computing for the Cloud Eric Bauer Lean Computing for the Cloud Новинка

Eric Bauer Lean Computing for the Cloud

6556.36 руб.
Applies lean manufacturing principles across the cloud service delivery chain to enable application and infrastructure service providers to sustainably achieve the shortest lead time, best quality, and value Applies lean thinking across the cloud service delivery chain to recognize and minimize waste Leverages lessons learned from electric power industry operations to operations of cloud infrastructure Applies insights from just-in-time inventory management to operation of cloud based applications Explains how traditional, Information Technology Infrastructure Library (ITIL) and Enhanced Telecom Operation Map (eTOM) capacity management evolves to lean computing for the cloud
Eleni Admassu KAP of Birth Preparedness and Compelication Readiness Eleni Admassu KAP of Birth Preparedness and Compelication Readiness Новинка

Eleni Admassu KAP of Birth Preparedness and Compelication Readiness

8652 руб.
This community based study has attempted to identify the knowledge, attitude and practice of birth preparedness and its complication readiness and factors associated with its utilization in north Gondar Zone Dabat district, North west Ethiopia. To that end, women's knowledge and practice towards birth preparedness was assessed by considering the recommended elements of birth preparedness and complication readiness, such as identify place of delivery, identify skilled delivery, saved money and identify mode of transport ahead of child birth. The contribution of these variable and other correlations, such as women's age, women's and husband's educational status, occupation, residence, annual income and other obstetric factors like ANC, parity were treated in the study.
C. Ingleton Palliative Care Nursing at a Glance C. Ingleton Palliative Care Nursing at a Glance Новинка

C. Ingleton Palliative Care Nursing at a Glance

2846.9 руб.
Palliative Care Nursing at a Glance is the perfect companion for nursing students, health and social care practitioners, and all those involved in palliative care delivery, both in the clinical and home setting. Written by an expert team of academics, nurses, educators and researchers it provides a concise and easy-to-read overview of all the concepts and clinical decision-making skills necessary for the provision of good-quality palliative and end-of-life care. Divided into six sections, the book includes coverage of all key clinical applications, principles of symptom management, palliative care approaches for a range of conditions and patient groups, exploration of the roles of the multi-professional team, as well as ethical challenges. Superbly illustrated, with full colour illustrations throughout Provides information on delivery of care in a range of settings Broad coverage makes it ideal reading for anyone involved in palliative care delivery User-friendly and accessible resource for those working in both specialist and non-specialist adult settings
Simon Edwards Think, Do, Show. The agile 2.0 secrets to building software people love to use Simon Edwards Think, Do, Show. The agile 2.0 secrets to building software people love to use Новинка

Simon Edwards Think, Do, Show. The agile 2.0 secrets to building software people love to use

2039 руб.
Think, Do, Show is a refreshing, simplified reboot of an agile 2.0 framework. This book presents a proven model which elegantly brings rapid continual delivery, close team collaboration, and people-centric focus together to truly empower delivery.If your job relies on you to rapidly deliver beautiful looking software that people love to use, then after reading this book you will be able to… Map out only the features you need to fix the problem(s) you’re trying to solve Create a simplified delivery schedule that everyone can understand and buy into Cut through corporate fog to ship software that adds value to your business and people’s lives Supercharge the delivery arm and give your team clear objectives Build a tribe of passionate followers and supporters within your organisation
Philip Jönsson, Steven Iveson F5 Networks Application Delivery Fundamentals Study Guide - Black and White Edition Philip Jönsson, Steven Iveson F5 Networks Application Delivery Fundamentals Study Guide - Black and White Edition Новинка

Philip Jönsson, Steven Iveson F5 Networks Application Delivery Fundamentals Study Guide - Black and White Edition

5202 руб.
The only study guide or material you'll need to prepare for the F5 Networks Application Delivery Fundamentals Exam. From the author of the most successful, popular and bestselling F5 technical books available today and the author of the first freely available study guide for this exam. The book's authors have taken great care to ensure all exam topics and fundamental networking areas are covered in full. The OSI Model, the Data Link, Network, Transport and Application Layers, Switching & Routing, F5 Solutions, Load Balancing, Security and Application Delivery Platforms are all covered in depth. No prior knowledge or experience is assumed. There are 13 chapters, 90 diagrams and over 70 test questions to ensure you have everything necessary to prepare for and pass the exam with confidence.

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Chitosan is a linear polysaccharide commercially produced by the deacetylation of chitin. It is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with otherwise unstable biomolecules – making it a valuable component in the formulation of biopharmaceutical drugs. Chitosan-Based Systems for Biopharmaceuticals provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. The book is divided in four different parts. Part I discusses general aspects of chitosan and its derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems. Part II deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. Part III discusses specific applications of chitosan and its derivatives for biopharmaceutical use. Finally, Part IV presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related to the development of biopharmaceutical products, as well as their patent status, and clinical application and potential. Topics covered include: chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals physical properties of chitosan and derivatives in sol and gel states absorption promotion properties of chitosan and derivatives biocompatibility and biodegradation of chitosan and derivatives biological and pharmacological activity of chitosan and derivatives biological, chemical and physical compatibility of chitosan and biopharmaceuticals approaches for functional modification or crosslinking of chitosan use of chitosan and derivatives in conventional biopharmaceutical dosage forms manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals chitosan and derivatives for biopharmaceutical use: mucoadhesive properties chitosan-based systems for mucosal delivery of biopharmaceuticals chitosan-based delivery systems for mucosal vaccination chitosan-based nanoparticulates for oral delivery of biopharmaceuticals chitosan-based systems for ocular delivery of biopharmaceuticals chemical modification of chitosan for delivery of DNA and siRNA target-specific chitosan-based nanoparticle systems for nucleic acid delivery functional PEGylated chitosan systems for biopharmaceuticals stimuli-sensitive chitosan-based systems for biopharmaceuticals chitosan copolymers for biopharmaceuticals application of chitosan for anti-cancer biopharmaceutical delivery chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine wound healing properties of chitosan and its use in wound dressing biopharmaceuticals toxicological properties of chitosan and derivatives for biopharmaceutical applications regulatory status of chitosan and derivatives patentability and intellectual property issues quality control and good manufacturing practice preclinical and clinical use of chitosan and derivatives for biopharmaceuticals Chitosan-Based Systems for Biopharmaceuticals is an important compendium of fundamental concepts, practical tools and applications of chitosan-based biopharmaceuticals for researchers in academia and industry working in drug formulation and delivery, biopharmaceuticals, medicinal chemistry, pharmacy, bioengineering and new materials development.
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