triazoles an attention causing moiety for medicinal chemists



Brian Fulton S. Drug Discovery for the Treatment of Addiction. Medicinal Chemistry Strategies Brian Fulton S. Drug Discovery for the Treatment of Addiction. Medicinal Chemistry Strategies Новинка

Brian Fulton S. Drug Discovery for the Treatment of Addiction. Medicinal Chemistry Strategies

9218.23 руб.
With addiction a key target for drug discovery efforts, this book fills an important and timely need for medicinal chemists who need to understand complex neuroscience issues. The author illustrates medicinal chemistry's prominent role in treating addiction and covers specific drugs of abuse including narcotics, stimulants, depressants, nicotine, and marijuana. • Interprets complex neuro- biological and pharmacological information, like the drug-reward system, for medicinal chemists • Emphasizes neurotransmitters and neurochemical mechanisms of addictive drugs • Pulls together information on the many potential drug targets for treating addiction • Stresses unique medicinal chemistry problems when describing pharmacology testing methods and drug development
Raimund Mannhold Drug Selectivity. An Evolving Concept in Medicinal Chemistry Raimund Mannhold Drug Selectivity. An Evolving Concept in Medicinal Chemistry Новинка

Raimund Mannhold Drug Selectivity. An Evolving Concept in Medicinal Chemistry

19560.84 руб.
The book «Drug Selectivity – An Evolving Concept in Medicinal Chemistry» provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.
Tsaioun Katya ADMET for Medicinal Chemists. A Practical Guide Tsaioun Katya ADMET for Medicinal Chemists. A Practical Guide Новинка

Tsaioun Katya ADMET for Medicinal Chemists. A Practical Guide

12165.89 руб.
This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.
Florencio Dörwald Zaragoza Lead Optimization for Medicinal Chemists. Pharmacokinetic Properties of Functional Groups and Organic Compounds Florencio Dörwald Zaragoza Lead Optimization for Medicinal Chemists. Pharmacokinetic Properties of Functional Groups and Organic Compounds Новинка

Florencio Dörwald Zaragoza Lead Optimization for Medicinal Chemists. Pharmacokinetic Properties of Functional Groups and Organic Compounds

2222.46 руб.
Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and synonyms to facilitate the location of any drug or functional group in the book. This compact working guide provides a wealth of information on the ways small structural modifications affect the pharmacokinetic properties of organic compounds, and offers plentiful, fact-based inspiration for the development of new drugs. This book is mainly aimed at medicinal chemists, but may also be of interest to graduate students in chemical or pharmaceutical sciences, preparing themselves for a job in the pharmaceutical industry, and to healthcare professionals in need of pharmacokinetic data.
David Crich Modern Synthetic Methods in Carbohydrate Chemistry. From Monosaccharides to Complex Glycoconjugates David Crich Modern Synthetic Methods in Carbohydrate Chemistry. From Monosaccharides to Complex Glycoconjugates Новинка

David Crich Modern Synthetic Methods in Carbohydrate Chemistry. From Monosaccharides to Complex Glycoconjugates

15649.39 руб.
The fields of glycochemistry and glycoscience are rich and varied and where much can be learned from Nature. As Nature is not always able to produce carbohydrates in quantities useful for not only in research but also as therapeutic agents, new ways need to be found to optimize the yield. This book presents an overview of the latest developments in the field of carbohydrates, ranging from de-novo approaches via cyclodextrin chemistry to the synthesis of such highly complex glycoconjugates as glycosphingolipids and GPI anchors. The main emphasis remains on the synthetic aspects making the book an excellent source of information for those already involved in carbohydrate chemistry, as well as for those organic chemists who are beginners in this field. Equally of interest to synthetic chemists, as well as medicinal chemists and biochemists.
Robert A. Goodnow, Jr. A Handbook for DNA-Encoded Chemistry. Theory and Applications for Exploring Chemical Space and Drug Discovery Robert A. Goodnow, Jr. A Handbook for DNA-Encoded Chemistry. Theory and Applications for Exploring Chemical Space and Drug Discovery Новинка

Robert A. Goodnow, Jr. A Handbook for DNA-Encoded Chemistry. Theory and Applications for Exploring Chemical Space and Drug Discovery

9993.65 руб.
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
Jacek Lipkowski Bioelectrochemistry. Fundamentals, Applications and Recent Developments Jacek Lipkowski Bioelectrochemistry. Fundamentals, Applications and Recent Developments Новинка

Jacek Lipkowski Bioelectrochemistry. Fundamentals, Applications and Recent Developments

16810.67 руб.
Bioelectrochemistry is a fast growing field at the interface between electrochemistry and other sciences such as biochemistry, analytical chemistry and medicinal chemistry. In the recent years, the methods and the understanding of the fundamentals have seen significant progress, which has led to rapid development in the field. Here, the expert editors have carefully selected contributions to best reflect the latest developments in this hot and rapidly growing interdisciplinary topic. The resulting excellent and timely overview of this multifaceted field covers recent methodological advances, as well as a range of new applications for analytical detection, drug screening, tumor therapy, and for energy conversion in biofuel cells. This book is a must-have for all Electrochemists, Biochemists, Analytical Chemists, and Medicinal Chemists.
Hugo Kubinyi Microwaves in Organic and Medicinal Chemistry Hugo Kubinyi Microwaves in Organic and Medicinal Chemistry Новинка

Hugo Kubinyi Microwaves in Organic and Medicinal Chemistry

18980.36 руб.
Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed, almost doubling the amount of chemical information with an additional volume. As in the predecessor, a short introductory section covers the theoretical background and evaluates currently available instrumentation and equipment. The main part of the book then goes on to systematically survey the complete range of published microwave-assisted synthesis methods from their beginnings in the 1990s to mid-2011, drawing on data from more than 5,000 reports and publications. Throughout, the focus is on those reactions, reagents and reaction conditions that work, and that are the most relevant for medicinal and natural products chemistry. A much expanded section is devoted to combinatorial, highthroughput and flow chemistry methods.
Hartwig John F. Catalyzed Carbon-Heteroatom Bond Formation Hartwig John F. Catalyzed Carbon-Heteroatom Bond Formation Новинка

Hartwig John F. Catalyzed Carbon-Heteroatom Bond Formation

18209.07 руб.
Written by an experienced editor widely acclaimed within the scientific community, this book covers everything from oxygen to nitrogen functionalities. From the contents: * Palladium-Catalyzed Syntheses of Five-Membered Saturated Heterocycles * The Formation of Carbon-Sulfur and Carbon-Selenium Bonds by Substitution and Addition Reactions Catalyzed by Transition Metal Complexes * Palladium-Catalysis for Oxidative 1,2-Difunctionalization of Alkenes * Palladium-Catalyzed Formation of Aromatic Heterocycles * Rhodium-Catalyzed Amination of C-H-Bonds * Transition Metal-Catalyzed Synthesis of Heterocycles * Copper-Catalyzed Synthesis of Azoles * Palladium(II)-Catalyzed C-N Bond Formation Involving Aminopalladation of Aklenes * Carbon-Heteroatom Bond Formation by Rh(I)-Catalyzed Ring-Opening Reactions * Recent Advances in Homogeneous Gold Catalysis: Formation of Carbon-Heteroatom Bonds The result is an indispensable source of information for the strategic planning of the synthetic routes for organic, catalytic and medicinal chemists, as well as chemists in industry.
Young Richard Drug Discrimination. Applications to Medicinal Chemistry and Drug Studies Young Richard Drug Discrimination. Applications to Medicinal Chemistry and Drug Studies Новинка

Young Richard Drug Discrimination. Applications to Medicinal Chemistry and Drug Studies

13593.19 руб.
Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agents Drug discrimination can be described as a «drug detection» procedure that uses a pharmacologically active agent as the subjective stimulus. Although the procedure does require some effort to implement, it can be an extremely important tool for understanding drug action. Whereas medicinal chemists should come to learn the types of information that drug discrimination studies can offer, pharmacologists and psychologists might come to realize how medicinal chemists can apply the types of information that the paradigm routinely provides. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies provides in-depth analyses of the nature and use of drugs as discriminative stimuli and bridges some of the numerous gaps between medicinal chemistry, pharmacology, and psychology. Stressing the practical aspects of drug discrimination, including types of procedures, study design, data, and interpretation, the book details the advantages and limitations of drug discrimination studies versus other pharmacologic evaluations. Practical information from leading researchers in the field addresses specific topics and techniques that are of interest in drug discovery, evaluation, and development. A groundbreaking new guide to the applications of drug discrimination studies for medicinal chemistry and neuroscience, Drug Discrimination is essential for any scientist, researcher, or student whose interests involve the design, development, and/or action of drugs acting at the level of the central nervous system.
Peter G. M. Wuts Greene's Protective Groups in Organic Synthesis Peter G. M. Wuts Greene's Protective Groups in Organic Synthesis Новинка

Peter G. M. Wuts Greene's Protective Groups in Organic Synthesis

7976.1 руб.
An indispensable reference for any practicing synthetic organic or medicinal chemist, this book continues the tradition of Greene’s as comprehensive in the overall scope of coverage, providing the most relevant and useful examples to illustrate each methodology. • Presents valuable material, on the application of protective groups in organic chemistry, that is not easily found by casual searching • Helps chemists to plan, investigate, and carry out organic syntheses in an efficient manner • Adds over 2800 new references to update since the publication of the last edition • Reviews of the prior edition: «An essential bible for the library or personal bookshelf of chemists performing complex synthesis.» (CHOICE, May 2007) «…the most up-to-date compilation available…should be an integral part of all institutional libraries…it is also highly recommended that individuals…maintain their own copy…» (Journal of Medicinal Chemistry, March 8, 2007) «…continues to be a comprehensive guide to the techniques for the formation and cleavage of protective groups.» (Journal of the American Chemical Society, January 31, 2007)
Tim Storr Ligand Design in Medicinal Inorganic Chemistry Tim Storr Ligand Design in Medicinal Inorganic Chemistry Новинка

Tim Storr Ligand Design in Medicinal Inorganic Chemistry

15106.96 руб.
Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.
Tomasz Janecki Natural Lactones and Lactams. Synthesis, Occurrence and Biological Activity Tomasz Janecki Natural Lactones and Lactams. Synthesis, Occurrence and Biological Activity Новинка

Tomasz Janecki Natural Lactones and Lactams. Synthesis, Occurrence and Biological Activity

2222.46 руб.
While there are numerous books on heterocycles and natural products, this text fills the need for an up-to-date summary focusing on recently developed and improved synthetic methods for the preparation of the most important classes of lactones and lactams – all in one volume. Comprehensive in its coverage, this book also provides readers with a brief description of the occurrence and biological or pharmaceutical activity of the compounds, and each chapter deals with a certain class of lactones or lactames to enable quick access to the information needed. A valuable resource for organic chemists, biochemists and medicinal chemists in academia and industry wanting to learn about successful synthetic routes leading to important natural products and use this as inspiration for their own work in the lab.
Leo Paquette A. Handbook of Reagents for Organic Synthesis, Sulfur-Containing Reagents Leo Paquette A. Handbook of Reagents for Organic Synthesis, Sulfur-Containing Reagents Новинка

Leo Paquette A. Handbook of Reagents for Organic Synthesis, Sulfur-Containing Reagents

15664.57 руб.
There are a lot of books available about the chemistry and biology of sulfur. However, this is the first book with a compilation of all relevant Sulfur containing reagents. Synthetic chemists, most particularly in the medicinal and pharmaceutical chemists, are often called upon to prepare compounds that contain Sulfur as a key structural feature. In the past, this seemed to be a domain for specialists; today every synthetic chemist working in these area is expected to synthesize compounds containing sulfides, sulfates, sulfones, etc. This book offers an important source of information for the selection and handling of the right reagents.
Peter Langer Asymmetric Synthesis of Non-Proteinogenic Amino Acids Peter Langer Asymmetric Synthesis of Non-Proteinogenic Amino Acids Новинка

Peter Langer Asymmetric Synthesis of Non-Proteinogenic Amino Acids

15880.91 руб.
Authored by two internationally recognized experts with an excellent track record, this much-needed reference summarizes latest research in the rapidly developing field of stereoselective synthesis of enantiomerically enriched amino acids, particularly of non-proteinogenic origin. It highlights several different catalytic and stoichiometric asymmetric methods for their synthesis and also provides information on origin, biological properties, different synthetic strategies and important applications in medicine and pharmacology. Essential reading for synthetic chemists working in the field of asymmetric synthesis, natural products and peptide synthesis, stereochemistry, medicinal chemistry, biochemistry, pharmacology, and biotechnology.
Ahmed Mushtaq Some Potential Medicinal Plants of North West Himalaya Ahmed Mushtaq Some Potential Medicinal Plants of North West Himalaya Новинка

Ahmed Mushtaq Some Potential Medicinal Plants of North West Himalaya

8377 руб.
Ayurvedic formulations of medicinal plants to combat human diseases are an attractive alternative to the synthetic drugs that have several limitations. Demand for medicinal plants all over the globe has increased due to growing recognition of natural products having no side effects and being easily available at affordable prices to the poor. Himalaya being one of the 34 biodiversity hot spots of the world is exceptionally rich in medicinal flora. Pir Panjal range of Kashmir Himalaya is notable for the presence of the nomadic tribes inhabiting upper reaches of the region and using many native plants for curing different diseases. This book approaches to highlight the need for research efforts that are needed for exploration, exploitation, documentation and conservation of the medicinal flora of Himalaya.
Eric Marsault Practical Medicinal Chemistry with Macrocycles. Design, Synthesis, and Case Studies Eric Marsault Practical Medicinal Chemistry with Macrocycles. Design, Synthesis, and Case Studies Новинка

Eric Marsault Practical Medicinal Chemistry with Macrocycles. Design, Synthesis, and Case Studies

17431 руб.
Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. • Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations • Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts • Covers design criteria, typical profile of current macrocycles, applications, and limitations
Sandra Gemma Structure-based Design of Drugs and Other Bioactive Molecules. Tools and Strategies Sandra Gemma Structure-based Design of Drugs and Other Bioactive Molecules. Tools and Strategies Новинка

Sandra Gemma Structure-based Design of Drugs and Other Bioactive Molecules. Tools and Strategies

10690.42 руб.
Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medicine. Traditionally, focus has been placed on computational, structural or synthetic methods only in isolation. This one-of-akind guide integrates all three skill sets for a complete picture of contemporary structure-based design. This practical approach provides the tools to develop a high-affinity ligand with drug-like properties for a given drug target for which a high-resolution structure exists. The authors use numerous examples of recently developed drugs to present «best practice» methods in structurebased drug design with both newcomers and practicing researchers in mind. By way of a carefully balanced mix of theoretical background and case studies from medicinal chemistry applications, readers will quickly and efficiently master the basic skills of successful drug design. This book is aimed at new and active medicinal chemists, biochemists, pharmacologists, natural product chemists and those working in drug discovery in the pharmaceutical industry. It is highly recommended as a desk reference to guide students in medicinal and chemical sciences as well as to aid researchers engaged in drug design today.
Wolfgang Fritzsche Molecular Plasmonics Wolfgang Fritzsche Molecular Plasmonics Новинка

Wolfgang Fritzsche Molecular Plasmonics

11232.84 руб.
Adopting a novel approach, this book provides a unique «molecular perspective» on plasmonics, concisely presenting the fundamentals and applications in a way suitable for beginners entering this hot field as well as for experienced researchers and practitioners. It begins by introducing readers to the optical effects that occur at the nanoscale and particularly their modification in the presence of biomolecules, followed by a concise yet thorough overview of the different methods for the actual fabrication of nanooptical materials. Further chapters address the relevant nanooptics, as well as the various approaches to combining nanostructures and biomolecules to achieve certain desired functionalities for applications in the fields of probing, sensing and particle manipulation. For analytical biologists, physical chemists, materials scientists and medicinal chemists.
Bahgat Hussein Synthesis and Reactions of Some New s-Triazole Derivatives Bahgat Hussein Synthesis and Reactions of Some New s-Triazole Derivatives Новинка

Bahgat Hussein Synthesis and Reactions of Some New s-Triazole Derivatives

5787 руб.
Various 1,2,4-triazoles found extensive investigations due to their useful application in different areas of biological activity and as industrial intermediates such as antiasthmatic, antiviral, antifungal, antimicrobial, antibacterial, insecticidal, amoebicidal, hypnotic,cytotoxic and hypotensive activities. This moiety was also found in potent agonist and antagonist receptor ligands, in HIV-1 protease inhibitors and in thrombin inhibitors. Along with these significant pharmaceutical uses, 1,2,4-triazole derivatives are effectively used in polymers, dyestuff, photographic chemicals and agricultural chemicals. In view of these findings and in continuation of our work in the same field we provide in this book, the synthesis of some new s-triazole derivatives and tested for antibacterial activity.
Elhassan Eiman, M. Ahmed Elhadi, S. Khalid Hassan Quality Assurance of Selected Sudanese Medicinal Plants Elhassan Eiman, M. Ahmed Elhadi, S. Khalid Hassan Quality Assurance of Selected Sudanese Medicinal Plants Новинка

Elhassan Eiman, M. Ahmed Elhadi, S. Khalid Hassan Quality Assurance of Selected Sudanese Medicinal Plants

8927 руб.
Medicinal plants are important in health and economic component of the floras in developed as well as developing countries. Increasing world-wide interest in herbal remedies, expanding reliance of local health care on traditional remedies, and a renewed interest in the development of pharmaceuticals from plant source have greatly increased trade in medicinal plant materials.The book is an inventory of the quality assurance of the selected Sudanese medicinal plants. It contains an introduction to medicinal plants importance as therapeutic source, economic value of phytomedicine, and medicinal plants local trade structure in Sudan. The book reveals the definition of quality assurance of the herbal medicinal plants products, and the quality standards of herbal products. It includes the material, methods and equipments used in the work. Both consumers and health-care professionals need up-to-date authoritative information on the safety and efficacy of medicinal plants. Academics and Pharmaceutical Companies have to devote themselves to research in medicinal plants quality assurance.
Karen Lackey Medicinal Chemistry Approaches to Personalized Medicine Karen Lackey Medicinal Chemistry Approaches to Personalized Medicine Новинка

Karen Lackey Medicinal Chemistry Approaches to Personalized Medicine

15184.14 руб.
Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues. Numerous case studies from the first generation of «personalized drugs» are presented, highlighting the challenges and opportunities for pharmaceutical development. While the majority of these examples are taken from the field of cancer treatment, other key emerging areas, such as neurosciences and inflammation, are also covered. With its careful balance of current and future approaches, this handbook is a prime knowledge source for every drug developer, and one that will remain up to date for some time to come. From the content: * Discovery of Predictive Biomarkers for Anticancer Drugs * Discovery and Development of Vemurafenib * Targeting Basal-Cell Carcinoma * G-Quadruplexes as Therapeutic Targets in Cancer * From Human Genetics to Drug Candidates: An Industrial Perspective on LRRK2 Inhibition as a Treatment for Parkinson's Disease * Therapeutic Potential of Kinases in Asthma * DNA Damage Repair Pathways and Synthetic Lethality * Medicinal Chemistry in the Context of the Human Genome and many more
Zhang Wei Green Techniques for Organic Synthesis and Medicinal Chemistry Zhang Wei Green Techniques for Organic Synthesis and Medicinal Chemistry Новинка

Zhang Wei Green Techniques for Organic Synthesis and Medicinal Chemistry

17016.34 руб.
An updated overview of the rapidly developing field of green engineering techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.
Nunes Suzana Pereira Membrane Technology, Volume 4. Membranes for Water Treatment Nunes Suzana Pereira Membrane Technology, Volume 4. Membranes for Water Treatment Новинка

Nunes Suzana Pereira Membrane Technology, Volume 4. Membranes for Water Treatment

19004.23 руб.
This ready reference on Membrane Technologies for Water Treatment, is an invaluable source detailing sustainable, emerging processes, to provide clean, energy saving and cost effective alternatives to conventional processes. The editors are internationally renowned leaders in the field, who have put together a first-class team of authors from academia and industry to present a highly approach to the subject. The book is an instrumental tool for Process Engineers, Chemical Engineers, Process Control Technicians, Water Chemists, Environmental Chemists, Materials Scientists and Patent Lawyers.
Baró Arturo M. Atomic Force Microscopy in Liquid. Biological Applications Baró Arturo M. Atomic Force Microscopy in Liquid. Biological Applications Новинка

Baró Arturo M. Atomic Force Microscopy in Liquid. Biological Applications

12324.92 руб.
About 40 % of current atomic force microscopy (AFM) research is performed in liquids, making liquid-based AFM a rapidly growing and important tool for the study of biological materials. This book focuses on the underlying principles and experimental aspects of AFM under liquid, with an easy-to-follow organization intended for new AFM scientists. The book also serves as an up-to-date review of new AFM techniques developed especially for biological samples. Aimed at physicists, materials scientists, biologists, analytical chemists, and medicinal chemists. An ideal reference book for libraries. From the contents: Part I: General Atomic Force Microscopy * AFM: Basic Concepts * Carbon Nanotube Tips in Atomic Force Microscopy with * Applications to Imaging in Liquid * Force Spectroscopy * Atomic Force Microscopy in Liquid * Fundamentals of AFM Cantilever Dynamics in Liquid * Environments * Single-Molecule Force Spectroscopy * High-Speed AFM for Observing Dynamic Processes in Liquid * Integration of AFM with Optical Microscopy Techniques Part II: Biological Applications * DNA and Protein-DNA Complexes * Single-Molecule Force Microscopy of Cellular Sensors * AFM-Based Single-Cell Force Spectroscopy * Nano-Surgical Manipulation of Living Cells with the AFM
Enzo Alessio Bioinorganic Medicinal Chemistry Enzo Alessio Bioinorganic Medicinal Chemistry Новинка

Enzo Alessio Bioinorganic Medicinal Chemistry

17413.92 руб.
This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.
Bruno Pignataro Molecules at Work. Selfassembly, Nanomaterials, Molecular Machinery Bruno Pignataro Molecules at Work. Selfassembly, Nanomaterials, Molecular Machinery Новинка

Bruno Pignataro Molecules at Work. Selfassembly, Nanomaterials, Molecular Machinery

12007.52 руб.
This book contains the contributions of selected young chemists from the field of nanotechnology and material sciences. The contributions are grouped under the following umbrella topics: Self assembly Nanomaterials Molecular Machinery This volume is an indispensable read for all materials scientists, organic, and inorganic chemists, Ph.D. students in chemistry and material sciences interested in seeing what tomorrow's chemistry will look like.
Christian Rojas M. Molecular Rearrangements in Organic Synthesis Christian Rojas M. Molecular Rearrangements in Organic Synthesis Новинка

Christian Rojas M. Molecular Rearrangements in Organic Synthesis

15106.96 руб.
Designed for practitioners of organic synthesis, this book helps chemists understand and take advantage of rearrangement reactions to enhance the synthesis of useful chemical compounds. Provides ready access to the genesis, mechanisms, and synthetic utility of rearrangement reactions Emphasizes strategic synthetic planning and implementation Covers 20 different rearrangement reactions Includes applications for synthesizing compounds useful as natural products, medicinal compounds, functional materials, and physical organic chemistry
Lavkush Dwivedi Important Medicinal Plants of India Lavkush Dwivedi Important Medicinal Plants of India Новинка

Lavkush Dwivedi Important Medicinal Plants of India

4500 руб.
India is a great repository of variety of medicinal plants. Presence of nearly 8000 species of medicinal plants has proved it one of the richest genetic resources of the world. Moreover, about 45000 plants species i.e. 12 % of global wealth of flowering plants are reported to occur in India, out of which nearly 33% are endemic. However, the use of plants as medicine is as old as human civilization and reported from 400-500 BC but, in the last couple of decades, global demand of herbal medicine has led to a quantum jump with 7% annual growth rate. However, several of them due to lack of scientific attention and acknowledgement are yet to be evaluated. Hence, an attempt is made in the present book to systematically compile the taxonomic, therapeutic and other detail of 52 important medicinal plants of India, so that they can be known, conserved, cropped and further researched for their maximum therapeutic utilization.
A. Stephen K. Hashmi Modern Gold Catalyzed Synthesis A. Stephen K. Hashmi Modern Gold Catalyzed Synthesis Новинка

A. Stephen K. Hashmi Modern Gold Catalyzed Synthesis

16459.73 руб.
With its impressive features, gold has led to completely new reaction types in recent years, which in turn have strongly influenced both organic catalysis and material science. Other fields where a significant amount of new results has been obtained include nanotechnology, self assembly/supramolecular systems and biochemical/medicinal chemistry. As a result, gold is one of the hottest topics in catalysis at the moment, with an increasing amount of research being carried out in this field. While focusing on homogeneous catalysis, this monograph also covers the main applications in heterogeneous catalysis. Following a look at the gold-catalyzed addition of heteroatom nucleophiles to alkynes, it goes on to discuss gold-catalyzed additions to allenes and alkenes, gold-catalyzed benzannulations, cycloisomerization and rearrangement reactions, as well as oxidation and reduction reactions. The whole is finished off with a section on gold-catalyzed aldol and related reactions and the application of gold-catalyzed reactions to natural product synthesis. Of interest to synthetic chemists and inorganic chemists, as well as organic chemists working in homogeneous catalysis, physical and technical chemists.
Peter Jacobi A. Introduction to Heterocyclic Chemistry Peter Jacobi A. Introduction to Heterocyclic Chemistry Новинка

Peter Jacobi A. Introduction to Heterocyclic Chemistry

5301.04 руб.
A unique approach to a core topic in organic chemistry presented by an experienced teacher to students and professionals Heterocyclic rings are present in the majority of known natural products, contributing to enormous structural diversity. In addition, they often possess significant biological activity. Medicinal chemists have embraced this last property in designing most of the small molecule drugs in use today. This book offers readers a fundamental understanding of the basics of heterocyclic chemistry and their occurrence in natural products such as amino acids, DNA, vitamins, and antibiotics. Based on class lectures that the author has developed over more than 40 years of teaching, it focuses on the chemistry of such heterocyclic substances and how they differ from carbocyclic systems. Introductory Heterocyclic Chemistry offers in-depth chapters covering naturally occurring heterocycles; properties of aromatic heterocycles; π-deficient heterocycles; π-excessive heterocycles; and ring transformations of heterocycles. It then offers an overview of 1,3-dipolar cycloadditions before finishing up with a back-to-basics section on nitriles and amidines. Presents a conversational approach to a fundamental topic in organic chemistry teaching Offers a unique look at this core organic chemistry topic via important naturally occurring and/or biologically active heterocycles Based on the author's many years of class lectures for teaching at the undergraduate and graduate level as well as pharmaceutical-industry courses Clear, concise, and accessible for advanced students of chemistry to gain a fundamental understanding of the basics of heterocyclic chemistry Introductory Heterocyclic Chemistry is an excellent text for undergraduate and graduate students as well as chemists in industrial environments in chemistry, pharmacy, medicinal chemistry, and biology.
Viktor Iaroshenko Organophosphorus Chemistry. From Molecules to Applications Viktor Iaroshenko Organophosphorus Chemistry. From Molecules to Applications Новинка

Viktor Iaroshenko Organophosphorus Chemistry. From Molecules to Applications

19560.84 руб.
Filling the gap for an up-to-date reference that presents the field of organophosphorus chemistry in a comprehensive and clearly structured way, this one-stop source covers the chemistry, properties, and applications from life science and medicine. Divided into two parts, the first presents the chemistry of various phosphorus-containing compounds and their synthesis, including ylides, acids, and heterocycles. The second part then goes on to look at applications in life science and bioorganic chemistry. Last but not least, such important practical aspects as 31P-NMR and protecting strategies for these compounds are presented. For organic, bioinorganic, and medicinal chemists, as well as those working on organometallics, and for materials scientists. The book, a contributed work, features a team of renowned scientists from around the world whose expertise spans the many aspects of modern organophosphorus chemistry.
Hugo Kubinyi Thermodynamics and Kinetics of Drug Binding Hugo Kubinyi Thermodynamics and Kinetics of Drug Binding Новинка

Hugo Kubinyi Thermodynamics and Kinetics of Drug Binding

14719.62 руб.
This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors.
Jacek Mlynarski Chiral Lewis Acids in Organic Synthesis Jacek Mlynarski Chiral Lewis Acids in Organic Synthesis Новинка

Jacek Mlynarski Chiral Lewis Acids in Organic Synthesis

14331.55 руб.
A complete overview covering the application of metal-based chiral Lewis acids from all parts of the periodic table, the Author emphasizes the most recent contributions to the field as well as prominent direction of development. The book discusses the design of chiral complexes as well as a wide spectrum of reactions promoted by various chiral Lewis acids, including water-compatible acids as well as the most important applications in the chemical and pharmaceutical industries. A must-have for catalytic and organic chemists working in the field, both in academia and industry, as well as pharmaceutical and medicinal chemists.
Kaladhar Dsvgk, M. a. Prasad, S. Sri Krishna Keerthi Ayurmedbase. an Ayurvedic Medicinal Database for Traditional and Ayurvedic Medicinal Systems Kaladhar Dsvgk, M. a. Prasad, S. Sri Krishna Keerthi Ayurmedbase. an Ayurvedic Medicinal Database for Traditional and Ayurvedic Medicinal Systems Новинка

Kaladhar Dsvgk, M. a. Prasad, S. Sri Krishna Keerthi Ayurmedbase. an Ayurvedic Medicinal Database for Traditional and Ayurvedic Medicinal Systems

1514 руб.
Skript aus dem Jahr 2014 im Fachbereich Informatik - Software, , Sprache: Deutsch, Abstract: In recent times focus on plant research has increased all over the world and a large body of evidence has been accumulated to highlight the immense potential of medicinal plants used in various traditional system of medicine. AyurMedBase is a medicinal plant database providing information and treatment of diseases. The database provides 147 plants information and their uses. The common name, scientific name and other details with ayurvedic uses have been presented. This database is highly useful to people in the treatment and cure of diseases naturally from plants of Andhra Pradesh.
Werngard Czechtizky Small Molecule Medicinal Chemistry. Strategies and Technologies Werngard Czechtizky Small Molecule Medicinal Chemistry. Strategies and Technologies Новинка

Werngard Czechtizky Small Molecule Medicinal Chemistry. Strategies and Technologies

11620.18 руб.
Stressing strategic and technological solutions to medicinal chemistry challenges, this book presents methods and practices for optimizing the chemical aspects of drug discovery. Chapters discuss benefits, challenges, case studies, and industry perspectives for improving drug discovery programs with respect to quality and costs. • Focuses on small molecules and their critical role in medicinal chemistry, reviewing chemical and economic advantages, challenges, and trends in the field from industry perspectives • Discusses novel approaches and key topics, like screening collection enhancement, risk sharing, HTS triage, new lead finding approaches, diversity-oriented synthesis, peptidomimetics, natural products, and high throughput medicinal chemistry approaches • Explains how to reduce design-make-test cycle times by integrating medicinal chemistry, physical chemistry, and ADME profiling techniques • Includes descriptive case studies, examples, and applications to illustrate new technologies and provide step-by-step explanations to enable them in a laboratory setting
Meier Michael A.R. Green Polymerization Methods. Renewable Starting Materials, Catalysis and Waste Reduction Meier Michael A.R. Green Polymerization Methods. Renewable Starting Materials, Catalysis and Waste Reduction Новинка

Meier Michael A.R. Green Polymerization Methods. Renewable Starting Materials, Catalysis and Waste Reduction

17811.49 руб.
Designing polymers and developing polymerization processes that are safe, prevent pollution, and are more efficient in the use of materials and engergy is an important topic in modern chemistry. Today, green polymer research can be seen increasingly in academia nd industry. It tackles all aspects of polymers and polymerization – everything from chemical feedstocks, synthetic pathways, and reaction media to the nature of the final polymer as related to its inherent nontoxicity or degradability. This book summarizes and evaluates the latest developments in green polymerization methods. Specifically, new catalytic methods and processes which incorporate renewable resources will be discussed by leading experts in the field of polymer chemistry. This book is a must-have for Polymer Chemists, Chemists Working with/on Organometallics, Biochemists, Physical Chemists, Chemical Engineers, Biotechnologists, Materials Scientists, and Catalytic Chemists.
Hugo Kubinyi Prodrugs and Targeted Delivery. Towards Better ADME Properties Hugo Kubinyi Prodrugs and Targeted Delivery. Towards Better ADME Properties Новинка

Hugo Kubinyi Prodrugs and Targeted Delivery. Towards Better ADME Properties

16268.25 руб.
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.
Albini Angelo Handbook of Synthetic Photochemistry Albini Angelo Handbook of Synthetic Photochemistry Новинка

Albini Angelo Handbook of Synthetic Photochemistry

15664.57 руб.
Unique in its focus on preparative impact rather than mechanistic details, this handbook provides an overview of photochemical reactions classed according to the structural feature that is built in the photochemical step, so as to facilitate use by synthetic chemists unfamiliar with this topic. An introductory section covers practical questions on how to run a photochemical reaction, while all classes of the most important photocatalytic reactions are also included. Perfect for organic synthetic chemists in academia and industry.
Bert Popping Molecular Biological and Immunological Techniques and Applications for Food Chemists Bert Popping Molecular Biological and Immunological Techniques and Applications for Food Chemists Новинка

Bert Popping Molecular Biological and Immunological Techniques and Applications for Food Chemists

12395.59 руб.
A guide to using molecular biology and immunological methods for the analysis of food Many of the analytical problems that food chemists face in the lab cannot be solved by chemistry alone, and so analytical chemists are turning to molecular biology and immunology for alternative approaches. Molecular Biological and Immunological Techniques and Applications for Food Chemists comprehensively explains the most important molecular biology and immunology methods, and illustrates their application in food analysis. Written by a distinguished group of experts, the coverage includes: Molecular Biological Methods—techniques explained, laboratory layout, PCR, real-time PCR, RFLP, SSCP, and sequencing Molecular Biology Applications—meat, genetically modified organisms (GMOs), food allergens, offal, and fish Immunological Methods—techniques explained and antibody-based detection methods Immunology Applications—animal speciation, international food allergen regulations (except Japanese), Japanese regulations and buckwheat allergen detection, egg allergen detection, soy allergen detection, milk allergen detection, gluten allergen detection, nut allergen detection, fish allergen detection, lupin allergen detection, mustard allergen detection, and celery allergen detection Clearly written and consistently edited to provide information to a wide range of readers, Molecular Biological and Immunological Techniques and Applications for Food Chemists offers an up-to-date reference for food scientists in government and industry, policymakers, and graduate-level students of food science, technology, and engineering. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.
Gunter Mayer The Chemical Biology of Nucleic Acids Gunter Mayer The Chemical Biology of Nucleic Acids Новинка

Gunter Mayer The Chemical Biology of Nucleic Acids

15267 руб.
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
H. Bennett The Chemical Formulary, Volume 1 H. Bennett The Chemical Formulary, Volume 1 Новинка

H. Bennett The Chemical Formulary, Volume 1

7002 руб.
There is hardly any technical library in the world in which the volumes of the Chemical Formulary (Volumes 1-34) do not occupy a prominent place. Chemists both experienced and beginner, continually refer to them. It does not duplicate any of the formulas included in previous volumes, but lists a wide array of modern and salable products from all branches of the chemical industries. An excellent reference for formulation problems.PREFACE - Chemistry, as taught in our schools and colleges, concerns chieflysynthesis, analysis, and engineering-and properly so. It is part of the rightfoundation for the education of the chemist.Many a chemist entering an Industry soon finds that most of the productsmanufactured by his concern are not synthetic or definite complex compounds,but are mixtures, blends, or highly complex compounds of whichhe knows little or nothing. The literature in this field, if any, may bemeager, scattered, or obsolete.Even chemists with years of experience In one or more Industries spendconsiderable time and effort in acquainting themselves with any new fieldwhich they may enter. Consulting chemists similarly have to solve problemsbrought to them from industries foreign to them. There was a definiteneed for an up-to-date compilation of formulae for chemical compoundingand treatment. Since the fields to be covered are many and varied, aneditorial board of chemists and engineers engaged in many industries wasformed.Many publications, laboratories, manufacturing firms...
Gunter Mayer The Chemical Biology of Nucleic Acids Gunter Mayer The Chemical Biology of Nucleic Acids Новинка

Gunter Mayer The Chemical Biology of Nucleic Acids

14873.97 руб.
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Halligan Katherine Troubletops and the New Baby Halligan Katherine Troubletops and the New Baby Новинка

Halligan Katherine Troubletops and the New Baby

683 руб.
Troubletops is always causing trouble - he just loves being the centre of attention! But when his mummy and daddy have a new baby, no-one even notices him anymore. How can Troubletops tell his fmily how he feels? This warm, funny tale will appeal to all children who have a new brother or sister on the way!
Gerd Folkers Protein Therapeutics Gerd Folkers Protein Therapeutics Новинка

Gerd Folkers Protein Therapeutics

26339.8 руб.
In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.
Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology Новинка

Goutam Brahmachari Bioactive Natural Products. Chemistry and Biology

17043.66 руб.
Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.
Alexandre Varnek Tutorials in Chemoinformatics Alexandre Varnek Tutorials in Chemoinformatics Новинка

Alexandre Varnek Tutorials in Chemoinformatics

7359.44 руб.
30 tutorials and more than 100 exercises in chemoinformatics, supported by online software and data sets Chemoinformatics is widely used in both academic and industrial chemical and biochemical research worldwide. Yet, until this unique guide, there were no books offering practical exercises in chemoinformatics methods. Tutorials in Chemoinformatics contains more than 100 exercises in 30 tutorials exploring key topics and methods in the field. It takes an applied approach to the subject with a strong emphasis on problem-solving and computational methodologies. Each tutorial is self-contained and contains exercises for students to work through using a variety of software packages. The majority of the tutorials are divided into three sections devoted to theoretical background, algorithm description and software applications, respectively, with the latter section providing step-by-step software instructions. Throughout, three types of software tools are used: in-house programs developed by the authors, open-source programs and commercial programs which are available for free or at a modest cost to academics. The in-house software and data sets are available on a dedicated companion website. Key topics and methods covered in Tutorials in Chemoinformatics include: Data curation and standardization Development and use of chemical databases Structure encoding by molecular descriptors, text strings and binary fingerprints The design of diverse and focused libraries Chemical data analysis and visualization Structure-property/activity modeling (QSAR/QSPR) Ensemble modeling approaches, including bagging, boosting, stacking and random subspaces 3D pharmacophores modeling and pharmacological profiling using shape analysis Protein-ligand docking Implementation of algorithms in a high-level programming language Tutorials in Chemoinformatics is an ideal supplementary text for advanced undergraduate and graduate courses in chemoinformatics, bioinformatics, computational chemistry, computational biology, medicinal chemistry and biochemistry. It is also a valuable working resource for medicinal chemists, academic researchers and industrial chemists looking to enhance their chemoinformatics skills.
Jan Gul, Hamayun Muhammad, Gul Jan Farzana Medicinal flora of Kumrate Valley KP Pakistan Jan Gul, Hamayun Muhammad, Gul Jan Farzana Medicinal flora of Kumrate Valley KP Pakistan Новинка

Jan Gul, Hamayun Muhammad, Gul Jan Farzana Medicinal flora of Kumrate Valley KP Pakistan

8039 руб.
This book covering the medicinal flora of the Kumrate valley. The book is focused on the importance of flora, threats to the flora and recommendation for the conservation of flora of Kumrate valley. This book will helps in the field of botany and forestry. The book has beautiful pictures and recommendation for the sustainable utilization of medicinal flora.This book has market value and valuable for Universities students and teachers.
Akter MD Alamgir Indigenous Medicinal Plant Species in Bangladesh Akter MD Alamgir Indigenous Medicinal Plant Species in Bangladesh Новинка

Akter MD Alamgir Indigenous Medicinal Plant Species in Bangladesh

9202 руб.
Once there was enormous number of medicinal plant species in Bangladesh and it is now in alarming situation. Though still now there is vast number of medicinal plant species present in some parts of the country. The reader can learn many things from this book and he or she will be gained a lot of knowledge from it. It is very much helpful for researchers specially for Forest Scientist, Environmental Specialist, Ecologist, Biodiversity Specialist, Herbal Medicine Doctors etc. So, it is for everybody who want to know about South Asia (Bangladesh)
Moe Kamal Plant Foods for Life. A New Method for Assessing the Nutritional Quality and Dietary Wellness of 100 Vegetables Moe Kamal Plant Foods for Life. A New Method for Assessing the Nutritional Quality and Dietary Wellness of 100 Vegetables Новинка

Moe Kamal Plant Foods for Life. A New Method for Assessing the Nutritional Quality and Dietary Wellness of 100 Vegetables

1327 руб.
"Plant Foods for Life" is a one-of-a-kind reference book written to help consumers around the world. An indispensable companion to improve a lifestyle, maintain a good health and restore wellness.The author exposes his new approach to assess nutritional and Medicinal foods.A resource book that shows what crop to choose, to avoid and which one is best to eat."Plant Foods for Life" is an encyclopedia, a produce market manual and natural health store. The book offers an impressive compendium of information of more than 100 vegetables.Topics include:- Botany, market and cuisine- Overall appraisal score- Food risks and benefits- Nutritional quality- Medicinal information...
Walter Korfmacher A. Mass Spectrometry for Drug Discovery and Drug Development Walter Korfmacher A. Mass Spectrometry for Drug Discovery and Drug Development Новинка

Walter Korfmacher A. Mass Spectrometry for Drug Discovery and Drug Development

10225.9 руб.
Facilitates the discovery and development of new, effective therapeutics With coverage of the latest mass spectrometry technology, this book explains how mass spectrometry can be used to enhance almost all phases of drug discovery and drug development, including new and emerging applications. The book's fifteen chapters have been written by leading pharmaceutical and analytical scientists. Their contributions are based on a thorough review of the current literature as well as their own experience developing new mass spectrometry techniques to improve the ability to discover and develop new and effective therapeutics. Mass Spectrometry for Drug Discovery and Drug Development begins with an overview of the types of mass spectrometers that facilitate drug discovery and development. Next it covers: HPLC–high-resolution mass spectrometry for quantitative assays Mass spectrometry for siRNA Quantitative analysis of peptides Mass spectrometry analysis of biological drugs Applications that support medicinal chemistry investigations Mass spectrometry imaging and profiling Throughout the book, detailed examples underscore the growing role of mass spectrometry throughout the drug discovery and development process. In addition, images of mass spectra are provided to explain how results are interpreted. Extensive references at the end of each chapter guide readers to the primary literature in the field. Mass Spectrometry for Drug Discovery and Drug Development is recommended for readers in pharmaceutics, including medicinal chemists, analytical chemists, and drug metabolism scientists. All readers will discover how mass spectrometry can streamline and advance new drug discovery and development efforts.
Antonio de la Hoz Microwaves in Organic Synthesis, 2 Volume Set Antonio de la Hoz Microwaves in Organic Synthesis, 2 Volume Set Новинка

Antonio de la Hoz Microwaves in Organic Synthesis, 2 Volume Set

38269.41 руб.
The third edition of the bestselling two-volume reference covers everything you need to know about microwave technology for synthesis – from the best equipment to nonthermal effects, from solid-support reactions to catalysis. Completely revised and updated with half of the authors completely new to the project, this comprehensive work is clearly divided into two parts on the fundamentals of microwave irradiation, and application of microwaves and synergies with other enabling techniques. Also new to this edition are chapters on on-line monitoring, flow chemistry, combination with ultrasounds and natural products, including multicomponent reactions. An indispensable source for organic, catalytic, physical, and medicinal chemists.
Daniel Hagn, Oliver Schöffski Orphan Drugs Daniel Hagn, Oliver Schöffski Orphan Drugs Новинка

Daniel Hagn, Oliver Schöffski Orphan Drugs

3089 руб.
"The promotion and development of medicinal products for the treatment of rare diseases require our particular attention, as health is our most valuable possession," said Ursula Schleicher, former Vice-President of the European Parliament.According to estimates, around 25 million people in Europe are suffering from 5,000 to 8,000 orphan diseases. Many of them are still waiting for medicines that will allow them to at least be able to lead a pain-free life, if not always a normal life. From a purely business-management viewpoint, the development of drugs for rare diseases is not always economical for the pharmaceutical industry. Nor can sufferers raise the funds themselves for research into the drugs that for them are vitally necessary. It is, therefore, a question of moral values and national priorities as to what extent society is prepared to help those affected.In 1999 the European Union adopted the Orphan Medicinal Products Regulation. This offers the biopharmaceutical and pharmaceutical industry incentives to develop orphan drugs. This book presents the European Orphan Medicinal Products Regulation and compares it with the rules of other countries. It also discusses the possibilities of creating further incentives.
Henry Trimen Medicinal Plants: Being Descriptions with Original Figures of the Principal Plants Employed in Medicine and an Account of the Characters, Properties, . and Products of Medicinal Value, Volume 1 Henry Trimen Medicinal Plants: Being Descriptions with Original Figures of the Principal Plants Employed in Medicine and an Account of the Characters, Properties, . and Products of Medicinal Value, Volume 1 Новинка

Henry Trimen Medicinal Plants: Being Descriptions with Original Figures of the Principal Plants Employed in Medicine and an Account of the Characters, Properties, . and Products of Medicinal Value, Volume 1

993 руб.
Эта книга — репринт оригинального издания, созданный на основе электронной копии высокого разрешения, которую очистили и обработали вручную, сохранив структуру и орфографию оригинального издания. Редкие, забытые и малоизвестные книги, изданные с петровских времен до наших дней, вновь доступны в виде печатных книг.
Andreas Winter Terpyridine-based Materials. For Catalytic, Optoelectronic and Life Science Applications Andreas Winter Terpyridine-based Materials. For Catalytic, Optoelectronic and Life Science Applications Новинка

Andreas Winter Terpyridine-based Materials. For Catalytic, Optoelectronic and Life Science Applications

16810.67 руб.
In recent years, the utilization of terpyridines both in macromolecular structure assembly and device chemistry has exploded, enabling, for example, supramolecular polymer architectures with switchable chemical and physical properties as well as novel functional materials for optoelectronic applications such as light-emitting diodes and solar cells. Further applications include the usage of terpyridines and their metal complexes as catalysts for asymmetric organic reactions and, in a biological context, as anti-tumor agents or biolabels. This book covers terpyridine-based materials topics ranging from syntheses, chemistry, and multinuclear metal complexes, right up to functionalized polymers, 3D-architectures, and surfaces. Aimed at materials scientists, (in)organic chemists, polymer chemists, complex chemists, physical chemists, biochemists, and libraries.
Robert Bentley Medicinal plants. Being descriptions with original figures of the principal plants employed in medicine and an account of the characters, properties, . their parts and products of medicinal value Robert Bentley Medicinal plants. Being descriptions with original figures of the principal plants employed in medicine and an account of the characters, properties, . their parts and products of medicinal value Новинка

Robert Bentley Medicinal plants. Being descriptions with original figures of the principal plants employed in medicine and an account of the characters, properties, . their parts and products of medicinal value

1042 руб.
Эта книга — репринт оригинального издания, созданный на основе электронной копии высокого разрешения, которую очистили и обработали вручную, сохранив структуру и орфографию оригинального издания. Редкие, забытые и малоизвестные книги, изданные с петровских времен до наших дней, вновь доступны в виде печатных книг.
Suresh Gor and Rajkumari Parwani Exploring the treasure of Ethnobotany Suresh Gor and Rajkumari Parwani Exploring the treasure of Ethnobotany Новинка

Suresh Gor and Rajkumari Parwani Exploring the treasure of Ethnobotany

3212 руб.
As plants are believed to have healing powers people have been using plants for the medicinal purpose since ancient times.Now in the modern era the scientific interest in the plants used for medicinal purpose has been reawakened.This book dwells into various aspects of ethnobotany and provides documentation of certain traditional ethnomedicinal plants which are also known for their commercial utilization.
Robert Liska Multiphoton Lithography. Techniques, Materials, and Applications Robert Liska Multiphoton Lithography. Techniques, Materials, and Applications Новинка

Robert Liska Multiphoton Lithography. Techniques, Materials, and Applications

14719.62 руб.
This first book on this fascinating, interdisciplinary topic meets the much-felt need for an up-to-date overview of the field. Written with both beginners and professionals in mind, this ready reference begins with an introductory section explaining the basics of the various multi-photon and photochemical processes together with a description of the equipment needed. A team of leading international experts provides the latest research results on such materials as new photoinitiators, hybrid photopolymers, and metallic carbon nanotube composites. They also cover promising applications and prospective trends, including photonic crystals, microfluidic devices, biological scaffolds, metamaterials, waveguides, and functionalized hydrogels. By bringing together the essentials for both industrial and academic researchers, this is an invaluable companion for materials scientists, polymer chemists, surface chemists, surface physicists, biophysicists, and medical scientists working with 3D micro- and nanostructures.
Ramesh Patel N. Green Biocatalysis Ramesh Patel N. Green Biocatalysis Новинка

Ramesh Patel N. Green Biocatalysis

17431 руб.
Green Biocatalysis presents an exciting green technology that uses mild and safe processes with high regioselectivity and enantioselectivity. Bioprocesses are carried out under ambient temperature and atmospheric pressure in aqueous conditions that do not require any protection and deprotection steps to shorten the synthetic process, offering waste prevention and using renewable resources. Drawing on the knowledge of over 70 internationally renowned experts in the field of biotechnology, Green Biocatalysis discusses a variety of case studies with emphases on process R&D and scale-up of enzymatic processes to catalyze different types of reactions. Random and directed evolution under process conditions to generate novel highly stable and active enzymes is described at length. This book features: A comprehensive review of green bioprocesses and application of enzymes in preparation of key compounds for pharmaceutical, fine chemical, agrochemical, cosmetic, flavor, and fragrance industries using diverse enzymatic reactions Discussion of the development of efficient and stable novel biocatalysts under process conditions by random and directed evolution and their applications for the development of environmentally friendly, efficient, economical, and sustainable green processes to get desired products in high yields and enantiopurity The most recent technological advances in enzymatic and microbial transformations and cuttingedge topics such as directed evolution by gene shuffling and enzyme engineering to improve biocatalysts With over 3000 references and 800 figures, tables, equations, and drawings, Green Biocatalysis is an excellent resource for biochemists, organic chemists, medicinal chemists, chemical engineers, microbiologists, pharmaceutical chemists, and undergraduate and graduate students in the aforementioned disciplines.
Joshua Brooks Playing for an Audience of One Joshua Brooks Playing for an Audience of One Новинка

Joshua Brooks Playing for an Audience of One

877 руб.
Learn to play for an Audience of One! Amidst the competing voices of the world, become attuned to hear God's voice. You soon will find your eyes and ears more drawn than ever to the One who most deserves your attention.

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30 tutorials and more than 100 exercises in chemoinformatics, supported by online software and data sets Chemoinformatics is widely used in both academic and industrial chemical and biochemical research worldwide. Yet, until this unique guide, there were no books offering practical exercises in chemoinformatics methods. Tutorials in Chemoinformatics contains more than 100 exercises in 30 tutorials exploring key topics and methods in the field. It takes an applied approach to the subject with a strong emphasis on problem-solving and computational methodologies. Each tutorial is self-contained and contains exercises for students to work through using a variety of software packages. The majority of the tutorials are divided into three sections devoted to theoretical background, algorithm description and software applications, respectively, with the latter section providing step-by-step software instructions. Throughout, three types of software tools are used: in-house programs developed by the authors, open-source programs and commercial programs which are available for free or at a modest cost to academics. The in-house software and data sets are available on a dedicated companion website. Key topics and methods covered in Tutorials in Chemoinformatics include: Data curation and standardization Development and use of chemical databases Structure encoding by molecular descriptors, text strings and binary fingerprints The design of diverse and focused libraries Chemical data analysis and visualization Structure-property/activity modeling (QSAR/QSPR) Ensemble modeling approaches, including bagging, boosting, stacking and random subspaces 3D pharmacophores modeling and pharmacological profiling using shape analysis Protein-ligand docking Implementation of algorithms in a high-level programming language Tutorials in Chemoinformatics is an ideal supplementary text for advanced undergraduate and graduate courses in chemoinformatics, bioinformatics, computational chemistry, computational biology, medicinal chemistry and biochemistry. It is also a valuable working resource for medicinal chemists, academic researchers and industrial chemists looking to enhance their chemoinformatics skills.
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